Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 10233036)

Published in Am J Physiol on May 01, 1999

Authors

G van Dijk1, R J Seeley, T E Thiele, M I Friedman, H Ji, C W Wilkinson, P Burn, L A Campfield, R Tenenbaum, D G Baskin, S C Woods, M W Schwartz

Author Affiliations

1: Department of Animal Physiology, University of Groningen, 9750 AA Haren, The Netherlands. g.van.dijk@bio.rug.nl

Articles by these authors

Central nervous system control of food intake. Nature (2000) 15.85

Epigenetic memory in induced pluripotent stem cells. Nature (2010) 14.31

Central nervous system control of food intake and body weight. Nature (2006) 11.89

Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell (1997) 11.35

Identification and expression cloning of a leptin receptor, OB-R. Cell (1995) 9.74

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science (1995) 9.09

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes (1993) 5.70

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity (1999) 5.38

Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors. J Exp Med (2001) 4.27

Intranasal insulin improves cognition and modulates beta-amyloid in early AD. Neurology (2007) 4.14

Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature (1979) 4.08

Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature (2001) 3.70

TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol (2001) 3.53

Identification of targets of leptin action in rat hypothalamus. J Clin Invest (1996) 3.49

Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nat Genet (1999) 3.37

Diabetes complications: why is glucose potentially toxic? Science (1996) 3.34

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat Neurosci (1998) 3.17

Pneumatosis intestinalis and portomesenteric venous gas in intestinal ischemia: correlation of CT findings with severity of ischemia and clinical outcome. AJR Am J Roentgenol (2001) 2.84

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes (1996) 2.83

Signals that regulate food intake and energy homeostasis. Science (1998) 2.70

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology (1998) 2.61

Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res (2003) 2.57

Fatal septicaemia after fibroid embolisation. Lancet (1999) 2.48

Degradation of transcription factor RFX5 during the inhibition of both constitutive and interferon gamma-inducible major histocompatibility complex class I expression in chlamydia-infected cells. J Exp Med (2000) 2.40

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes (1997) 2.32

Insulin increases CSF Abeta42 levels in normal older adults. Neurology (2003) 2.27

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation. Science (1993) 2.25

Origin of nanomechanical cantilever motion generated from biomolecular interactions. Proc Natl Acad Sci U S A (2001) 2.22

Neural control of the endocrine pancreas. Physiol Rev (1974) 2.21

Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men. J Clin Endocrinol Metab (2000) 2.19

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity. EMBO J (1992) 2.16

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation. Science (1993) 2.10

Insulin in the brain: a hormonal regulator of energy balance. Endocr Rev (1992) 2.03

Melanocortin receptors in leptin effects. Nature (1997) 2.01

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes (1990) 2.00

Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis. Am J Hum Genet (1997) 1.94

Molecular classification of the inherited hamartoma polyposis syndromes: clearing the muddied waters. Am J Hum Genet (1998) 1.92

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. Proc Natl Acad Sci U S A (1996) 1.80

Increased CSF cortisol in AD is a function of APOE genotype. Neurology (2001) 1.78

Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL. Proc Natl Acad Sci U S A (1995) 1.78

Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma. Eur Respir J (2011) 1.74

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest (1993) 1.67

Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade. Am J Physiol Regul Integr Comp Physiol (2000) 1.66

Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology (1992) 1.65

Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res (1999) 1.64

Obesity, diabetes and the central nervous system. Diabetologia (1998) 1.62

Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res (1998) 1.62

The usefulness of lateral neck roentgenograms in laryngotracheobronchitis. Am J Dis Child (1979) 1.62

Transport function and regulation of mitochondrial uncoupling proteins 2 and 3. J Biol Chem (1999) 1.61

Gender differences in age-related changes in HPA axis reactivity. Psychoneuroendocrinology (2001) 1.60

A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat Struct Biol (2001) 1.60

Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60

Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypothalamo-pituitary-adrenal axis. Alcohol Clin Exp Res (2000) 1.58

The OB protein (leptin) pathway--a link between adipose tissue mass and central neural networks. Horm Metab Res (1996) 1.57

Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose. Arch Gen Psychiatry (1999) 1.57

Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. Diabetes (1999) 1.57

Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception. Br J Nutr (1999) 1.56

Food intake and the regulation of body weight. Annu Rev Psychol (2000) 1.55

Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. J Neurosci (1998) 1.54

Effect of prolonged moderate and severe energy restriction and refeeding on plasma leptin concentrations in obese women. Am J Clin Nutr (1999) 1.52

Activation in brain energy regulation and reward centers by food cues varies with choice of visual stimulus. Int J Obes (Lond) (2009) 1.50

Regulation of src family tyrosine kinases in lymphocytes. Trends Biochem Sci (1993) 1.49

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes (2000) 1.48

Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy. Science (1982) 1.47

Cloning and expression of a novel angiotensin II receptor subtype. J Biol Chem (1992) 1.47

Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes (1995) 1.44

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A (1997) 1.44