J D Helmann

Author PubWeight™ 75.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors. Mol Microbiol 1998 3.62
2 DNA sequence analysis suggests that expression of flagellar and chemotaxis genes in Escherichia coli and Salmonella typhimurium is controlled by an alternative sigma factor. Proc Natl Acad Sci U S A 1987 3.53
3 Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions. Proc Natl Acad Sci U S A 1995 2.91
4 Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis. J Bacteriol 1998 2.70
5 The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility sigma factor of B. subtilis. Cell 1989 2.62
6 Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes. J Bacteriol 1996 2.57
7 Studies of sigma D-dependent functions in Bacillus subtilis. J Bacteriol 1990 2.53
8 Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins. Mol Microbiol 2000 2.38
9 A promoter melting region in the primary sigma factor of Bacillus subtilis. Identification of functionally important aromatic amino acids. J Mol Biol 1994 2.27
10 The A. tumefaciens transcriptional activator OccR causes a bend at a target promoter, which is partially relaxed by a plant tumor metabolite. Cell 1992 2.13
11 Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA. Mol Microbiol 2001 2.07
12 Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions. J Bacteriol 1993 2.07
13 OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis. J Bacteriol 2001 1.98
14 Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search. J Mol Biol 1998 1.98
15 Bacillus subtilis MrgA is a Dps(PexB) homologue: evidence for metalloregulation of an oxidative-stress gene. Mol Microbiol 1995 1.94
16 Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter. Mol Microbiol 2000 1.94
17 Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W. Mol Microbiol 1999 1.89
18 Promoter recognition by Bacillus subtilis sigmaW: autoregulation and partial overlap with the sigmaX regulon. J Bacteriol 1998 1.83
19 Bacterial Ohr and OsmC paralogues define two protein families with distinct functions and patterns of expression. Microbiology 2001 1.83
20 FosB, a cysteine-dependent fosfomycin resistance protein under the control of sigma(W), an extracytoplasmic-function sigma factor in Bacillus subtilis. J Bacteriol 2001 1.83
21 The Bacillus subtilis sigma(X) protein is an extracytoplasmic function sigma factor contributing to survival at high temperature. J Bacteriol 1997 1.76
22 Open complex formation by Escherichia coli RNA polymerase: the mechanism of polymerase-induced strand separation of double helical DNA. Mol Microbiol 1995 1.68
23 Promoter architecture in the flagellar regulon of Bacillus subtilis: high-level expression of flagellin by the sigma D RNA polymerase requires an upstream promoter element. Proc Natl Acad Sci U S A 1995 1.60
24 Interaction of Bacillus subtilis Fur (ferric uptake repressor) with the dhb operator in vitro and in vivo. J Bacteriol 1999 1.43
25 Dual chemotaxis signaling pathways in Bacillus subtilis: a sigma D-dependent gene encodes a novel protein with both CheW and CheY homologous domains. J Bacteriol 1994 1.39
26 The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT. J Bacteriol 1994 1.37
27 The delta subunit of Bacillus subtilis RNA polymerase. An allosteric effector of the initiation and core-recycling phases of transcription. J Mol Biol 1994 1.25
28 FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant. J Bacteriol 1996 1.25
29 Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury(II) binding domains. Biochemistry 1989 1.19
30 DNA-melting at the Bacillus subtilis flagellin promoter nucleates near -10 and expands unidirectionally. J Mol Biol 1997 1.15
31 Structural analysis of the Bacillus subtilis delta factor: a protein polyanion which displaces RNA from RNA polymerase. J Mol Biol 1995 1.14
32 Chemotaxis in Bacillus subtilis requires either of two functionally redundant CheW homologs. J Bacteriol 1994 1.14
33 Mutations in multidrug efflux homologs, sugar isomerases, and antimicrobial biosynthesis genes differentially elevate activity of the sigma(X) and sigma(W) factors in Bacillus subtilis. J Bacteriol 2000 1.11
34 The -10 region is a key promoter specificity determinant for the Bacillus subtilis extracytoplasmic-function sigma factors sigma(X) and sigma(W). J Bacteriol 2001 1.11
35 Restoration of motility to an Escherichia coli fliA flagellar mutant by a Bacillus subtilis sigma factor. Proc Natl Acad Sci U S A 1992 1.09
36 Expression, abundance, and RNA polymerase binding properties of the delta factor of Bacillus subtilis. J Biol Chem 1999 1.06
37 The Bacillus subtilis flagellar regulatory protein sigma D: overproduction, domain analysis and DNA-binding properties. J Mol Biol 1995 1.05
38 Genetic and physiological studies of Bacillus subtilis sigma A mutants defective in promoter melting. J Bacteriol 1994 1.03
39 sigma factor mutations affecting the sequence-selective interaction of RNA polymerase with -10 region single-stranded DNA. Nucleic Acids Res 1997 1.01
40 Pathway of promoter melting by Bacillus subtilis RNA polymerase at a stable RNA promoter: effects of temperature, delta protein, and sigma factor mutations. Biochemistry 1995 1.00
41 A mismatch bubble in double-stranded DNA suffices to direct precise transcription initiation by Escherichia coli RNA polymerase. J Biol Chem 1994 1.00
42 Mutations in sigma factor that affect the temperature dependence of transcription from a promoter, but not from a mismatch bubble in double-stranded DNA. Biochemistry 1994 0.99
43 Adenines at -11, -9 and -8 play a key role in the binding of Bacillus subtilis Esigma(A) RNA polymerase to -10 region single-stranded DNA. Nucleic Acids Res 1999 0.94
44 RNA polymerase sigma factor determines start-site selection but is not required for upstream promoter element activation on heteroduplex (bubble) templates. Proc Natl Acad Sci U S A 1997 0.94
45 Interactions between the promoter regions of nitrogenase structural genes (nifHDK2) and DNA-binding proteins from N2- and ammonium-grown cells of the archaeon Methanosarcina barkeri 227. J Bacteriol 1998 0.83