Published in Transgenic Res on November 01, 1998
Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis. J Exp Med (2008) 1.70
Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis. J Natl Cancer Inst (2012) 1.47
Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues. Am J Pathol (2008) 1.38
Keratinocyte but not endothelial cell-specific overexpression of Tie2 leads to the development of psoriasis. Am J Pathol (2009) 1.32
Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep (2001) 1.28
A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice. Am J Pathol (2005) 1.04
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proc Natl Acad Sci U S A (2012) 0.95
Cutaneous manipulation of vascular growth factors leads to alterations in immunocytes, blood vessels and nerves: Evidence for a cutaneous neurovascular unit. J Dermatol Sci (2010) 0.93
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature. BMC Dev Biol (2010) 0.90
Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease. Am J Pathol (2004) 0.90
Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells. Mol Cell Biol (2013) 0.89
A new mouse model for temporal- and tissue-specific control of extracellular superoxide dismutase. Genesis (2009) 0.82
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation. J Clin Invest (2016) 0.82
RUNX3 maintains the mesenchymal phenotype after termination of the Notch signal. J Biol Chem (2011) 0.82
Tie1 controls angiopoietin function in vascular remodeling and inflammation. J Clin Invest (2016) 0.81
Cell-cell interactions influence vascular reprogramming by Prox1 during embryonic development. PLoS One (2013) 0.79
CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy. Diabetes (2016) 0.79
Vasculotide, an Angiopoietin-1 mimetic, ameliorates several features of experimental atopic dermatitis-like disease. BMC Res Notes (2016) 0.75
Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems. Exp Ther Med (2014) 0.75
flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development (1993) 3.66
A murine model of hereditary hemorrhagic telangiectasia. J Clin Invest (1999) 2.64
Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis. Immunity (1998) 2.46
SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival. Genes Dev (1999) 2.31
Tie receptors: new modulators of angiogenic and lymphangiogenic responses. Nat Rev Mol Cell Biol (2001) 2.05
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. Cardiovasc Res (2001) 1.95
The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling. J Exp Med (1998) 1.88
Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J Biol Chem (1999) 1.60
The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene (1998) 1.57
Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins. J Biol Chem (2001) 1.29
Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep (2001) 1.28
Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. EMBO J (2001) 1.23
Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation. Curr Biol (1999) 1.18
Functions of Tie1 and Tie2 receptor tyrosine kinases in vascular development. Curr Top Microbiol Immunol (1999) 1.09
The SH2-containing inositol polyphosphate 5-phosphatase, ship, is expressed during hematopoiesis and spermatogenesis. Blood (1998) 1.08
VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis. Blood (2000) 1.05
Tek/Tie2 signaling: new and old partners. Cancer Metastasis Rev (2000) 1.00
Chronic systemic delivery of angiopoietin-2 reveals a possible independent angiogenic effect. Am J Physiol Heart Circ Physiol (2006) 0.94
Analysis of phosphorylation sites in the exon 1 region of E1A proteins of human adenovirus type 5. Virology (1989) 0.87
Molecular mechanisms in lymphangiogenesis: model systems and implications in human disease. Clin Genet (2003) 0.86
The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor. J Biol Chem (2000) 0.86
Molecular cloning of multiple isoforms of synaptojanin 2 and assignment of the gene to mouse chromosome 17A2-3.1. Biochem Biophys Res Commun (1998) 0.79
Molecular cloning and chromosomal localization in human and mouse of the SH2-containing inositol phosphatase, INPP5D (SHIP). Amgen EST Program. Genomics (1997) 0.78
A negative regulatory role for Y1111 on the Tie-2 RTK. Cell Signal (2009) 0.75
Assignment of the Dokr gene to mouse chromosome 14D2-D3 by fluorescence in situ hybridization. Genomics (1998) 0.75