Published in Stem Cells on January 01, 1999
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A (2003) 3.46
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med (2010) 2.42
STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3. Proc Natl Acad Sci U S A (2005) 2.32
Essential role of STAT3 in body weight and glucose homeostasis. Mol Cell Biol (2004) 1.74
Reduction of Stat3 activity attenuates HIV-induced kidney injury. J Am Soc Nephrol (2009) 1.70
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. J Mol Med (Berl) (2013) 1.64
Pathogenesis and immune response of Crimean-Congo hemorrhagic fever virus in a STAT-1 knockout mouse model. J Virol (2010) 1.49
Therapeutic modulators of STAT signalling for human diseases. Nat Rev Drug Discov (2013) 1.33
MicroRNAs and STAT interplay. Semin Cancer Biol (2011) 1.28
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3. Proc Natl Acad Sci U S A (2007) 1.21
In vivo identification of novel STAT5 target genes. Nucleic Acids Res (2008) 1.19
Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis. Proc Natl Acad Sci U S A (2011) 1.16
Stat3 directly controls the expression of Tbx5, Nkx2.5, and GATA4 and is essential for cardiomyocyte differentiation of P19CL6 cells. J Biol Chem (2010) 1.16
Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis. Mol Carcinog (2010) 1.12
STATs get their move on. JAKSTAT (2013) 1.08
Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice. Infect Immun (2006) 1.05
STAT signaling in mammary gland differentiation, cell survival and tumorigenesis. Mol Cell Endocrinol (2013) 1.04
Estrogen and progesterone are critical regulators of Stat5a expression in the mouse mammary gland. Endocrinology (2007) 1.02
PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway. Mol Vis (2008) 0.99
Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration. J Biol Chem (2011) 0.98
Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice. Neoplasia (2011) 0.95
STAT3 in Cancer-Friend or Foe? Cancers (Basel) (2014) 0.93
Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors. Biochemistry (2010) 0.90
STAT 5a expression in various lesions of the breast. Virchows Arch (2005) 0.90
The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis. JAKSTAT (2013) 0.90
Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level. Toxicol Sci (2012) 0.89
STATs: An Old Story, Yet Mesmerizing. Cell J (2015) 0.89
Gene targeting in mice: a review. Methods Mol Biol (2013) 0.88
Helminth regulation of host IL-4Ralpha/Stat6 signaling: mechanism underlying NOS-2 inhibition by Trichinella spiralis. Proc Natl Acad Sci U S A (2005) 0.85
LIF-STAT signaling and trophoblast biology. JAKSTAT (2013) 0.84
Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients. J Immunother Cancer (2014) 0.83
Punta Toro virus (Bunyaviridae, Phlebovirus) infection in mice: strain differences in pathogenesis and host interferon response. Virology (2009) 0.82
Role of STAT3 in in vitro transformation triggered by TRK oncogenes. PLoS One (2010) 0.82
Dysregulation of janus kinases and signal transducers and activators of transcription in cancer. Am J Cancer Res (2011) 0.80
Dietary aflatoxin-induced stunting in a novel rat model: evidence for toxin-induced liver injury and hepatic growth hormone resistance. Pediatr Res (2015) 0.80
The Role of STAT3 in Thyroid Cancer. Cancers (Basel) (2014) 0.80
Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast. J Exp Med (2013) 0.80
Modulation of PKCdelta signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3. Am J Physiol Lung Cell Mol Physiol (2008) 0.80
Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy. Oncotarget (2016) 0.79
STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection. Sci Rep (2016) 0.79
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling. Mol Carcinog (2014) 0.79
Constitutive activation of signal transducer and activator of transcription 3 regulates expression of vascular endothelial growth factor in human meningioma differentiation. J Cancer Res Clin Oncol (2010) 0.78
STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects. J Inflamm (Lond) (2012) 0.78
Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma Multiforme. Biomed Res Int (2015) 0.78
Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses. PLoS One (2016) 0.77
Working out mechanisms of controlled/physiologic inflammation in the GI tract. Immunol Res (2012) 0.77
Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition. J Exp Clin Cancer Res (2013) 0.77
Laboratory animal models to study foot-and-mouth disease: a review with emphasis on natural and vaccine-induced immunity. J Gen Virol (2014) 0.76
Protein malnutrition alters spleen cell proliferation and IL-2 and IL-10 production by affecting the STAT-1 and STAT-3 balance. Inflammation (2014) 0.76
Reversed Expression of the JAK/STAT Pathway Related Proteins Prolactin Receptor and STAT5a in Normal and Abnormal Breast Epithelial Cells. Breast Cancer (Auckl) (2008) 0.76
Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells. JAKSTAT (2013) 0.76
A Crimean-Congo hemorrhagic fever (CCHF) viral vaccine expressing nucleoprotein is immunogenic but fails to confer protection against lethal disease. Hum Vaccin Immunother (2016) 0.76
A developmentally controlled competitive STAT5-PU.1 DNA binding mechanism regulates activity of the Ig κ E3' enhancer. J Immunol (2012) 0.76
Ketamine Corrects Stress-Induced Cognitive Dysfunction through JAK2/STAT3 Signaling in the Orbitofrontal Cortex. Neuropsychopharmacology (2016) 0.75
Effects of cereal fiber on leptin resistance and sensitivity in C57BL/6J mice fed a high-fat/cholesterol diet. Food Nutr Res (2016) 0.75
Extracellular vesicle-mediated phenotype switching in malignant and non-malignant colon cells. BMC Cancer (2015) 0.75
STATdb: a specialised resource for the STATome. PLoS One (2014) 0.75
Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex. Mol Cancer Res (2017) 0.75
A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models. PLoS Negl Trop Dis (2017) 0.75
Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug. Mol Cell Biochem (2017) 0.75
Development of vaccines against Crimean-Congo haemorrhagic fever virus. Vaccine (2017) 0.75