Deficits in female reproductive function in GH-R-KO mice; role of IGF-I.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMID 10342852)

Published in Endocrinology on June 01, 1999

Authors

N Danilovich1, D Wernsing, K T Coschigano, J J Kopchick, A Bartke

Author Affiliations

1: Department of Physiology, Southern Illinois University, Carbondale 62901-6512, USA.

Articles citing this

Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci (2009) 2.08

Somatotropic signaling: trade-offs between growth, reproductive development, and longevity. Physiol Rev (2013) 1.50

Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocr Rev (2010) 1.44

Divergent roles of growth factors in the GnRH regulation of puberty in mice. J Clin Invest (2010) 1.13

Insulin-like growth factor-I activates KiSS-1 gene expression in the brain of the prepubertal female rat. Endocrinology (2008) 1.12

Jak2 is necessary for neuroendocrine control of female reproduction. J Neurosci (2011) 0.99

Insulin-like growth factor-1 stimulation of hypothalamic KiSS-1 gene expression is mediated by Akt: effect of alcohol. Neuroscience (2009) 0.97

Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action. J Physiol (2006) 0.97

Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice. Endocrinology (2003) 0.94

Prepubertal exposure to arsenic(III) suppresses circulating insulin-like growth factor-1 (IGF-1) delaying sexual maturation in female rats. Reprod Toxicol (2013) 0.91

Short-term alcohol administration alters KiSS-1 gene expression in the reproductive hypothalamus of prepubertal female rats. Alcohol Clin Exp Res (2009) 0.89

Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1. J Ovarian Res (2012) 0.89

Effects of SERM (selective estrogen receptor modulator) treatment on growth and proliferation in the rat uterus. Reprod Biol Endocrinol (2003) 0.86

The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1). Front Neuroendocrinol (2014) 0.85

Hypothalamic actions and interactions of alcohol and IGF-1 on the expression of glial receptor protein tyrosine phosphatase-β during female pubertal development. Alcohol Clin Exp Res (2011) 0.84

Actions and interactions of alcohol and insulin-like growth factor-1 on female pubertal development. Alcohol Clin Exp Res (2009) 0.84

Gene-environment interactions, not neonatal growth hormone deficiency, time puberty in female rhesus monkeys. Biol Reprod (2007) 0.82

Aging-related characteristics of growth hormone receptor/binding protein gene-disrupted mice. Age (Dordr) (2006) 0.79

Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries. Age (Dordr) (2014) 0.77

Growth hormone actions during development influence adult phenotype and longevity. Exp Gerontol (2016) 0.76

Effects of human growth hormone on gonadotropin-releasing hormone neurons in mice. Korean J Pediatr (2010) 0.75

Prenatal Alcohol Exposure and Pair Feeding Differentially Impact Puberty and Reproductive Development in Female Rats: Role of the Kisspeptin System. Alcohol Clin Exp Res (2016) 0.75

Sex-specific regulation of weight and puberty by the Lin28/let-7 axis. J Endocrinol (2015) 0.75

Rising maternal circulating GH during murine pregnancy suggests placental regulation. Endocr Connect (2017) 0.75

Alcohol and Puberty. Alcohol Res (2017) 0.75

Articles by these authors

Dwarf mice and the ageing process. Nature (1996) 6.12

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology (2000) 3.67

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc Natl Acad Sci U S A (1997) 3.42

Essential role of growth hormone in ischemia-induced retinal neovascularization. Science (1997) 2.11

The doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J (1991) 2.02

Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice. J Endocrinol (2002) 1.94

Differences in intracellular DNA ligation after microinjection and transfection. Mol Cell Biol (1984) 1.73

Cell-free synthesis of a precursor polyprotein containing both gag and pol gene products by Rauscher murine leukemia virus 35S RNA. Cell (1978) 1.71

Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects. Dev Biol (2001) 1.66

Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse. Exp Biol Med (Maywood) (2001) 1.64

Endodeoxyribonuclease activity associated with Rauscher murine leukemia virus. J Virol (1981) 1.61

Tryptic peptide analysis of gag and gag-pol gene products of Rauscher murine leukemia virus. J Virol (1979) 1.61

Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. Horm Behav (2001) 1.57

Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol Behav (2001) 1.56

Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene. Endocrinology (1999) 1.52

Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: effect of lactogenic hormones. Endocrinology (1995) 1.52

Effect of intron size on splicing efficiency in retroviral transcripts. Nucleic Acids Res (1982) 1.46

Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights. Biogerontology (2003) 1.40

Growth hormone gene expression in eukaryotic cells directed by the Rous sarcoma virus long terminal repeat or cytomegalovirus immediate-early promoter. Gene (1985) 1.39

Antioxidative mechanisms and plasma growth hormone levels: potential relationship in the aging process. Endocrine (1999) 1.31

Biological activity of cloned retroviral DNA in microinjected cells. Proc Natl Acad Sci U S A (1981) 1.29

Decreased survival of embryos in yellow (A-y-a) female mice. J Hered (1966) 1.29

Evidence supporting dual, IGF-I-independent and IGF-I-dependent, roles for GH in promoting longitudinal bone growth. J Endocrinol (2004) 1.28

Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm Metab Res (2002) 1.25

Low body temperature in long-lived Ames dwarf mice at rest and during stress. Physiol Behav (1999) 1.25

Studies of aging in ames dwarf mice: Effects of caloric restriction. J Am Aging Assoc (2000) 1.23

Higher number of stem cells in the bone marrow of circulating low Igf-1 level Laron dwarf mice--novel view on Igf-1, stem cells and aging. Leukemia (2011) 1.20

Postnatal development of the Sertoli cell barrier, tubular lumen, and cytoskeleton of Sertoli and myoid cells in the rat, and their relationship to tubular fluid secretion and flow. Am J Anat (1989) 1.18

Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology (1999) 1.17

Biosynthesis of reverse transcriptase from Rauscher murine leukemia virus by synthesis and cleavage of a gag-pol read-through viral precursor polyprotein. Proc Natl Acad Sci U S A (1978) 1.17

Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Mol Cell Biol (2000) 1.16

The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol (1995) 1.16

Premature ageing in transgenic mice expressing different growth hormone genes. J Reprod Fertil Suppl (1993) 1.16

The response of two types of dwarf mice to growth hormone, thyrotropin, and thyroxine. Gen Comp Endocrinol (1965) 1.14

Strange females increase plasma testosterone levels in male mice. Science (1975) 1.10

Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Mol Endocrinol (1991) 1.10

Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. J Endocrinol (2000) 1.10

Pituitary and testicular function in growth hormone receptor gene knockout mice. Endocrinology (1999) 1.09

Transgenic models of growth hormone action. Annu Rev Nutr (1999) 1.09

Growth hormone (GH)-induced dimerization inhibits phorbol ester-stimulated GH receptor proteolysis. J Biol Chem (2001) 1.08

Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice. Endocrinology (1991) 1.07

Etiology of growth hormone deficiency in little, Ames, and Snell dwarf mice. Endocrinology (1983) 1.06

The role of prolactin in the regulation of testis function: the effects of prolactin and luteinizing hormone on the plasma levels of testosterone and androstenedione in hypophysectomized rats. J Endocrinol (1972) 1.06

Ethanol, nicotine, amphetamine, and aspartame consumption and preferences in C57BL/6 and DBA/2 mice. Pharmacol Biochem Behav (1995) 1.05

The use of proteomics to study infectious diseases. Infect Disord Drug Targets (2008) 1.04

Apoptosis of male germ cells, a generalized or a cell type-specific phenomenon? Endocrinology (1995) 1.03

Effects of growth hormone on hypothalamic catalase and Cu/Zn superoxide dismutase. Free Radic Biol Med (2000) 1.03

Purification and physiochemical properties of a recombinant bovine growth hormone produced by cultured murine fibroblasts. Endocrinology (1986) 1.02

Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology (1973) 1.01

Glomerulosclerosis and body growth are mediated by different portions of bovine growth hormone. Studies in transgenic mice. Lab Invest (1993) 1.01

Could a deficiency in growth hormone signaling be beneficial to the aging brain? Physiol Behav (2004) 1.00

Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH-induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization. J Biol Chem (1999) 0.99

Growth hormone improves body composition, fasting blood glucose, glucose tolerance and liver triacylglycerol in a mouse model of diet-induced obesity and type 2 diabetes. Diabetologia (2009) 0.99

Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist. Br J Cancer (2001) 0.99

Effects of growth hormone overexpression and growth hormone resistance on neuroendocrine and reproductive functions in transgenic and knock-out mice. Proc Soc Exp Biol Med (1999) 0.98

Reduced number of VSELs in the bone marrow of growth hormone transgenic mice indicates that chronically elevated Igf1 level accelerates age-dependent exhaustion of pluripotent stem cell pool: a novel view on aging. Leukemia (2011) 0.97

Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice. Horm Metab Res (2004) 0.97

Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse. Proc Soc Exp Biol Med (1995) 0.96

Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice. Proc Natl Acad Sci U S A (1990) 0.96

Induction of endogenous insulin-like growth factor-I secretion alters the hypothalamic-pituitary-testicular function in growth hormone-deficient adult dwarf mice. Biol Reprod (1993) 0.96

Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice. Endocrinology (2000) 0.95

Rapid analysis of small nucleic acid samples by gel electrophoresis. Anal Biochem (1981) 0.95

In vitro and in vivo studies of antagonistic effects of human growth hormone analogs. J Biol Chem (1994) 0.94

Increased sensitivity of seminal vesicles to testosterone in a mouse strain with low plasma testosterone levels. J Endocrinol (1974) 0.93

Sertoli cells in testes containing or lacking germ cells: a comparative study of paracrine effects using the W (c-kit) gene mutant mouse model. Anat Rec (1994) 0.92

Ultrastructural aspects of the goiter in cog/cog mice. J Hered (1988) 0.92

Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span. J Gerontol A Biol Sci Med Sci (2001) 0.92

Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice. J Endocrinol (1999) 0.92

Effects of streptozotocin treatment in growth hormone (GH) and GH antagonist transgenic mice. Endocrinology (1995) 0.91

cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. Biochem J (2000) 0.91

A growth hormone (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary rat adipocytes. Endocrinology (1992) 0.91

The effects of weight cycling on lifespan in male C57BL/6J mice. Int J Obes (Lond) (2012) 0.91

A comparison of bovine growth-hormone gene expression in mouse L cells directed by the Moloney murine-leukemia virus long terminal repeat, simian virus-40 early promoter or cytomegalovirus immediate-early promoter. Gene (1988) 0.90

The growth hormone (GH)-axis of GH receptor/binding protein gene-disrupted and metallothionein-human GH-releasing hormone transgenic mice: hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback. Endocrinology (2001) 0.90

Evidence for growth hormone (GH) autoregulation in pituitary somatotrophs in GH antagonist-transgenic mice and GH receptor-deficient mice. Am J Pathol (2000) 0.90

Immunohistological study of the anterior pituitary gland - pars distalis and pars intermedia - in dwarf mice. Cell Tissue Res (1982) 0.90

Morphometric studies on hamster testes in gonadally active and inactive states: light microscope findings. Biol Reprod (1988) 0.90

A comparison of bovine growth hormone expression directed by bGH genomic or intronless DNA in transiently transfected eukaryotic cells. Gene (1987) 0.90

Porcine growth hormone receptor cDNA sequence. Nucleic Acids Res (1990) 0.89

Gonadotropin secretion, synthesis, and gene expression in human growth hormone transgenic mice and in Ames dwarf mice. Endocrinology (1993) 0.89

Inhibitory avoidance and appetitive learning in aged normal mice: comparison with transgenic mice having elevated plasma growth hormone levels. Neurobiol Learn Mem (1997) 0.89

Testicular function in mouse strains with different age of sexual maturation. J Hered (1974) 0.89

Co-expression of bovine growth hormone (GH) and human GH antagonist genes in transgenic mice. Endocrinology (1997) 0.88

Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation. Mol Endocrinol (1996) 0.88

Correlative morphology and endocrinology of Sertoli cells in hamster testes in active and inactive states of spermatogenesis. Endocrinology (1989) 0.88

Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice. Am J Physiol (1999) 0.88

Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene. Kidney Int Suppl (1993) 0.88

Evidence for episodic secretion of testosterone in laboratory mice. Steroids (1975) 0.88

Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation. J Biol Chem (1996) 0.88

Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin, increased aortic eNOS expression, and altered cardiovascular structure and function. Am J Physiol Endocrinol Metab (2007) 0.87