Published in J Gen Physiol on June 01, 1999
Control of calcium oscillations by membrane fluxes. Proc Natl Acad Sci U S A (2004) 1.72
A dynamic model of the type-2 inositol trisphosphate receptor. Proc Natl Acad Sci U S A (2002) 1.57
Calcium oscillations. Cold Spring Harb Perspect Biol (2011) 1.56
On the role of stochastic channel behavior in intracellular Ca2+ dynamics. Biophys J (2003) 1.40
Hybrid stochastic and deterministic simulations of calcium blips. Biophys J (2007) 1.40
Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation. Biochim Biophys Acta (2008) 1.27
Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells. J Physiol (2005) 1.19
A model of calcium waves in pancreatic and parotid acinar cells. Biophys J (2003) 1.13
Cytosolic Ca(2+) and Ca(2+)-activated Cl(-) current dynamics: insights from two functionally distinct mouse exocrine cells. J Physiol (2002) 1.11
Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase. J Biol Chem (2010) 1.08
The type 2 inositol (1,4,5)-trisphosphate (InsP3) receptor determines the sensitivity of InsP3-induced Ca2+ release to ATP in pancreatic acinar cells. J Biol Chem (2008) 1.02
A buffering SERCA pump in models of calcium dynamics. Biophys J (2006) 0.95
Regulation of the type III InsP(3) receptor by InsP(3) and ATP. Biophys J (2000) 0.95
Dynamics of a three-variable nonlinear model of vasomotion: comparison of theory and experiment. Biophys J (2007) 0.90
Stabilizing role of calcium store-dependent plasma membrane calcium channels in action-potential firing and intracellular calcium oscillations. Biophys J (2005) 0.87
Modelling calcium microdomains using homogenisation. J Theor Biol (2007) 0.86
Inhibition of serine/threonine phosphatase enhances arachidonic acid-induced [Ca2+]i via protein kinase A. Am J Physiol Cell Physiol (2008) 0.82
Spatiotemporal organization of Ca dynamics: a modeling-based approach. HFSP J (2010) 0.78
Comparison of models for IP3 receptor kinetics using stochastic simulations. PLoS One (2013) 0.77
Computational Model of Ca2+ Wave Propagation in Human Retinal Pigment Epithelial ARPE-19 Cells. PLoS One (2015) 0.75
Modelling mechanism of calcium oscillations in pancreatic acinar cells. J Bioenerg Biomembr (2014) 0.75
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release. Science (1991) 6.13
Elementary and global aspects of calcium signalling. J Physiol (1997) 5.08
A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration. Proc Natl Acad Sci U S A (1992) 4.41
Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature (1989) 3.65
Calcium oscillations. J Biol Chem (1990) 3.55
Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate. Cell (1993) 3.53
Type I, II, and III inositol 1,4,5-trisphosphate receptors are unequally susceptible to down-regulation and are expressed in markedly different proportions in different cell types. J Biol Chem (1995) 3.20
Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas. Cell (1993) 3.20
Inhibition by Ca2+ of inositol trisphosphate-mediated Ca2+ liberation: a possible mechanism for oscillatory release of Ca2+. Proc Natl Acad Sci U S A (1990) 3.14
Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps. J Biol Chem (1992) 3.09
A single-pool model for intracellular calcium oscillations and waves in the Xenopus laevis oocyte. Biophys J (1993) 3.08
Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux. Cell (1995) 2.89
Cyclic AMP-dependent phosphorylation of a brain inositol trisphosphate receptor decreases its release of calcium. Proc Natl Acad Sci U S A (1988) 2.63
Equations for InsP3 receptor-mediated [Ca2+]i oscillations derived from a detailed kinetic model: a Hodgkin-Huxley like formalism. J Theor Biol (1994) 2.41
Type III InsP3 receptor channel stays open in the presence of increased calcium. Nature (1998) 2.26
Inositol 1,4,5-trisphosphate-gated channels in cerebellum: presence of multiple conductance states. J Neurosci (1991) 2.01
Inositol 1,4,5-trisphosphate (InsP3) and calcium interact to increase the dynamic range of InsP3 receptor-dependent calcium signaling. J Gen Physiol (1997) 2.00
Localization of the type 3 inositol 1,4,5-trisphosphate receptor in the Ca2+ wave trigger zone of pancreatic acinar cells. J Biol Chem (1994) 1.95
The inositol 1,4,5-trisphosphate (InsP3) receptor. J Membr Biol (1995) 1.89
Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol (1978) 1.80
The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate. Nature (1994) 1.76
Mechanism of Ca2+ wave propagation in pancreatic acinar cells. J Biol Chem (1992) 1.66
Minimal requirements for calcium oscillations driven by the IP3 receptor. EMBO J (1997) 1.60
Mechanisms of calcium oscillations and waves: a quantitative analysis. FASEB J (1995) 1.60
Ca2+ oscillations induced by hormonal stimulation of individual fura-2-loaded hepatocytes. J Biol Chem (1989) 1.59
Inositol trisphosphate receptors: Ca2+-modulated intracellular Ca2+ channels. Biochim Biophys Acta (1998) 1.57
Molecular and functional evidence for multiple Ca2+-binding domains in the type 1 inositol 1,4,5-trisphosphate receptor. J Biol Chem (1997) 1.54
Differential regulation of types-1 and -3 inositol trisphosphate receptors by cytosolic Ca2+. Biochem J (1997) 1.49
Oscillating intracellular Ca2+ signals evoked by activation of receptors linked to inositol lipid hydrolysis: mechanism of generation. J Membr Biol (1990) 1.49
Calcium and inositol trisphosphate receptors. J Membr Biol (1995) 1.41
The inositol triphosphate receptor family. Cell Signal (1996) 1.40
Oscillations of cytosolic calcium in single pancreatic acinar cells stimulated by acetylcholine. FEBS Lett (1988) 1.38
Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptors. Biochem J (1997) 1.38
Inositol 1,4,5-trisphosphate and calcium regulate the calcium channel function of the hepatic inositol 1,4,5-trisphosphate receptor. J Biol Chem (1997) 1.33
Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells. J Biol Chem (1998) 1.31
Reversible desensitization of inositol trisphosphate-induced calcium release provides a mechanism for repetitive calcium spikes. J Biol Chem (1996) 1.29
Simplification and analysis of models of calcium dynamics based on IP3-sensitive calcium channel kinetics. Biophys J (1996) 1.29
Theoretical analysis of calcium wave propagation based on inositol (1,4,5)-trisphosphate (InsP3) receptor functional properties. Cell Calcium (1994) 1.28
Calcium oscillations in pituitary gonadotrophs: comparison of experiment and theory. Proc Natl Acad Sci U S A (1994) 1.27
Biphasic effects of cytosolic Ca2+ on Ins(1,4,5)P3-stimulated Ca2+ mobilization in hepatocytes. J Biol Chem (1993) 1.22
Synchronized oscillation of Ca2+ entry and Ca2+ release in agonist-stimulated AR42J cells. J Biol Chem (1991) 1.15
Rapid activation and partial inactivation of inositol trisphosphate receptors by inositol trisphosphate. Biochemistry (1998) 1.14
Quantal release, incremental detection, and long-period Ca2+ oscillations in a model based on regulatory Ca2+-binding sites along the permeation pathway. Biophys J (1996) 1.11
Acetylcholine and cholecystokinin induce different patterns of oscillating calcium signals in pancreatic acinar cells. Cell Calcium (1991) 1.09
Oscillatory mode of calcium signaling in rat pancreatic acinar cells. Am J Physiol (1990) 1.08
Intercellular calcium waves in rat pancreatic acini: mechanism of transmission. Am J Physiol (1996) 1.08
Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release. II. Effect of cAMP-dependent protein kinase. Am J Physiol (1990) 1.07
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell. Proc Natl Acad Sci U S A (1998) 1.06
Multiple mechanisms by which protein kinase A potentiates inositol 1,4,5-trisphosphate-induced Ca2+ mobilization in permeabilized hepatocytes. Biochem J (1993) 1.04
Ca2+ oscillations in pancreatic acinar cells: spatiotemporal relationships and functional implications. Cell Calcium (1993) 1.02
Phosphorylation of the inositol trisphosphate receptor in isolated rat hepatocytes. J Biol Chem (1993) 1.02
Gap junction communication modulates [Ca2+]i oscillations and enzyme secretion in pancreatic acini. J Biol Chem (1993) 1.00
Receptor-activated cytoplasmic Ca2+ oscillations in pancreatic acinar cells: generation and spreading of Ca2+ signals. Cell Calcium (1991) 0.99
Sensing and refilling calcium stores in an excitable cell. Biophys J (1997) 0.97
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase. Biochemistry (1996) 0.96
Cyclic AMP-dependent phosphorylation of the inositol-1,4,5-trisphosphate receptor inhibits Ca2+ release from platelet membranes. Biochem Biophys Res Commun (1992) 0.95
Activation of the plasma membrane Ca2+ pump during agonist stimulation of pancreatic acini. J Biol Chem (1992) 0.94
Spacial compartmentalization of Ca2+ signaling complexes in pancreatic acini. J Biol Chem (1996) 0.92
Two different spatiotemporal patterns for Ca2+ oscillations in pancreatic acinar cells: evidence of a role for protein kinase C in Ins(1,4,5)P3-mediated Ca2+ signalling. Cell Calcium (1993) 0.90
nNOS and Ca2+ influx in rat pancreatic acinar and submandibular salivary gland cells. Cell Calcium (1997) 0.89
Structure and function of inositol 1,4,5-trisphosphate receptor. Jpn J Pharmacol (1997) 0.88
Inositol trisphosphate analogues induce different oscillatory patterns in Xenopus oocytes. Cell Regul (1990) 0.88
Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors. Biochem J (1997) 0.87
Regulation of the inositol 1,4,5-trisphosphate-activated Ca2+ channel by activation of G proteins. J Biol Chem (1996) 0.87
Differential regulation of Ca2+ release-activated Ca2+ influx by heterotrimeric G proteins. J Biol Chem (1995) 0.86
A cloned CCK-A receptor transduces multiple signals in response to full and partial agonists. Am J Physiol (1993) 0.85
Signal-induced Ca2+ oscillations through the regulation of the inositol 1,4,5-trisphosphate-gated Ca2+ channel: an allosteric model. J Theor Biol (1997) 0.82
Relationship between hormonal, GTP and Ins(1,4,5)P3-stimulated Ca2+ uptake and release in pancreatic acinar cells. Biochem J (1989) 0.81
Simultaneous presence of cAMP and cGMP exert a co-ordinated inhibitory effect on the agonist-evoked Ca2+ signal in pancreatic acinar cells. Pflugers Arch (1996) 0.80
Regulation of intracellular calcium in epithelial cells. Semin Cell Biol (1990) 0.76
A single-pool model for intracellular calcium oscillations and waves in the Xenopus laevis oocyte. Biophys J (1993) 3.08
Control of calcium oscillations by membrane fluxes. Proc Natl Acad Sci U S A (2004) 1.72
Identification of a ryanodine receptor in rat heart mitochondria. J Biol Chem (2001) 1.67
Signaling pathways through which insulin regulates CCAAT/enhancer binding protein alpha (C/EBPalpha) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression. J Biol Chem (1997) 1.60
Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. J Biol Chem (1998) 1.36
Calcium wave propagation in pancreatic acinar cells: functional interaction of inositol 1,4,5-trisphosphate receptors, ryanodine receptors, and mitochondria. J Gen Physiol (2000) 1.35
Targeted phosphorylation of inositol 1,4,5-trisphosphate receptors selectively inhibits localized Ca2+ release and shapes oscillatory Ca2+ signals. J Biol Chem (2000) 1.29
Comparison of the action of isoproterenol and several related compounds on blood pressure, heart and bronchioles. Arch Int Pharmacodyn Ther (1966) 1.15
Two-dimensional model of calcium waves reproduces the patterns observed in Xenopus oocytes. Biophys J (1992) 1.14
A model of calcium waves in pancreatic and parotid acinar cells. Biophys J (2003) 1.13
Transient oscillatory force-length behavior of activated airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2009) 1.13
Acetylsalicylic acid: inhibition of platelet aggregation in the rabbit. J Pharmacol Exp Ther (1971) 1.13
A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini. J Biol Chem (1998) 1.13
Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice. J Clin Invest (1997) 1.09
A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations. Proc Natl Acad Sci U S A (2006) 1.07
A biomechanical model of agonist-initiated contraction in the asthmatic airway. Respir Physiol Neurobiol (2009) 1.04
Secretagogues cause ubiquitination and down-regulation of inositol 1, 4,5-trisphosphate receptors in rat pancreatic acinar cells. Gastroenterology (1999) 1.01
Calcium oscillations in a triplet of pancreatic acinar cells. Biophys J (2004) 1.01
Receptor-activated cytoplasmic Ca2+ oscillations in pancreatic acinar cells: generation and spreading of Ca2+ signals. Cell Calcium (1991) 0.99
Phototransduction in cones: an inverse problem in enzyme kinetics. Bull Math Biol (1989) 0.96
Analysis of a reduced model of corticotroph action potentials. J Theor Biol (1998) 0.93
Optical measurement of stimulus-evoked membrane dynamics in single pancreatic acinar cells. Am J Physiol (1998) 0.92
Modeling of the modulation by buffers of Ca2+ release through clusters of IP3 receptors. Biophys J (2009) 0.92
Stress distributions in vascular aneurysms: factors affecting risk of aneurysm rupture. J Surg Res (1993) 0.91
Ultrastructure and cell-cell coupling of cardiac myocytes differentiating in embryonic stem cell cultures. Cell Motil Cytoskeleton (1997) 0.90
Regulation of protein synthesis by cholecystokinin in rat pancreatic acini involves PHAS-I and the p70 S6 kinase pathway. Gastroenterology (1998) 0.90
Halothane and octanol block Ca2+ oscillations in pancreatic acini by multiple mechanisms. Am J Physiol (1995) 0.90
Paracrine mediation of calcium signaling in human SK-N-MCIXC neuroepithelioma cells. Am J Physiol (1996) 0.90
A mathematical analysis of obstructed diffusion within skeletal muscle. Biophys J (2009) 0.90
CRHSP-28 regulates Ca(2+)-stimulated secretion in permeabilized acinar cells. J Biol Chem (2001) 0.89
Light adaptation in turtle cones. Testing and analysis of a model for phototransduction. Biophys J (1991) 0.88
Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells. Am J Physiol (1997) 0.88
p70s6k is activated by CCK in rat pancreatic acini. Am J Physiol (1997) 0.87
Intracellular calcium waves. Adv Second Messenger Phosphoprotein Res (1995) 0.86
Substance P and bombesin elevate cytosolic Ca2+ by different molecular mechanisms in a rat pancreatic acinar cell line. J Physiol (1990) 0.86
Comparison of fura-2 imaging and electrophysiological analysis of murine calcium channel alpha 1 subunits coexpressed with novel beta 2 subunit isoforms. Mol Pharmacol (1995) 0.85
Intercellular spiral waves of calcium. J Theor Biol (1998) 0.85
Effects of okadaic acid indicate a role for dephosphorylation in pancreatic stimulus-secretion coupling. Am J Physiol (1992) 0.84
Endothelin-activated calcium signaling in enteric glia derived from neonatal guinea pig. Am J Physiol (1997) 0.84
Modulation of InsP3 receptor properties by phosphorylation: targeting of PKA to InsP3 receptors shapes oscillatory calcium signals in pancreatic acinar cells. J Korean Med Sci (2000) 0.83
Extracellular ATP mediates Ca2+ signaling in cultured myenteric neurons via a PLC-dependent mechanism. Am J Physiol (1996) 0.83
Mutation of carboxyl-terminal threonine residues in human m3 muscarinic acetylcholine receptor modulates the extent of sequestration and desensitization. Mol Pharmacol (1995) 0.83
Stimulus-secretion coupling of pancreatic digestive enzyme secretion. Digestion (1997) 0.83
Multiple inhibitory effects of genistein on stimulus-secretion coupling in rat pancreatic acini. Am J Physiol (1994) 0.82
Cromakalim (BRL 34915) and diazoxide activate ATP-regulated potassium channels in insulin-secreting cells. Pflugers Arch (1989) 0.82
Effects of alanine on insulin-secreting cells: patch-clamp and single cell intracellular Ca2+ measurements. Biochim Biophys Acta (1990) 0.82
Heterotrimeric G-protein Gq/11 localized on pancreatic zymogen granules is involved in calcium-regulated amylase secretion. J Biol Chem (1997) 0.81
Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells. Regul Pept (1995) 0.81
A simple method for high temporal resolution calcium imaging with dual excitation dyes. Biophys J (1998) 0.81
Comparative study of the effects of cromakalim (BRL 34915) and diazoxide on membrane potential, [Ca2+]i and ATP-sensitive potassium currents in insulin-secreting cells. J Membr Biol (1990) 0.80
Caffeine- and ryanodine-sensitive Ca2+ stores in cultured guinea pig myenteric neurons. Am J Physiol (1996) 0.79
Generation of action potentials in a mathematical model of corticotrophs. Biophys J (1997) 0.79
CCK activates p90rsk in rat pancreatic acini through protein kinase C. Am J Physiol (1997) 0.78
Spontaneous calcium oscillations in clonal endocrine pancreatic glucagon-secreting cells. Biochem Biophys Res Commun (1994) 0.78
Mathematical modelling of prolactin-receptor interaction and the corollary for prolactin receptor gene expression in skin. J Theor Biol (2005) 0.77
Agonist-specific calcium signaling and phosphoinositide hydrolysis in human SK-N-MCIXC neuroepithelioma cells. J Neurochem (1994) 0.76
Stimulant-evoked depolarization and increase in [Ca2+]i in insulin-secreting cells is dependent on external Na+. J Membr Biol (1990) 0.76
Intra- and intercellular calcium signaling in human neuroepithelioma cells. J Lipid Mediat Cell Signal (1996) 0.75
Characterization of cholecystokininA receptor agonist activity by a family of cholecystokininB receptor antagonists. J Pharmacol Exp Ther (1994) 0.75
Cassaine analogs. II. 7-deoxy basic esters. J Med Chem (1967) 0.75
Cassaine analogs. IV. Distant analogs of cassaine. J Med Chem (1967) 0.75
Chronic and multigeneration toxicities of small concentrations of cadmium in the diet of rats. Ecotoxicol Environ Saf (1981) 0.75