PubRank

P De Camilli

Author PubWeight™ 295.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminals. Nature 1995 7.81
2 Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 1983 7.55
3 Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 1990 6.71
4 Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25. Nature 1993 5.73
5 Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis. Nat Cell Biol 1999 5.56
6 Generation of high curvature membranes mediated by direct endophilin bilayer interactions. J Cell Biol 2001 5.37
7 Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections. J Cell Biol 1983 4.73
8 Accessory factors in clathrin-dependent synaptic vesicle endocytosis. Nat Rev Neurosci 2000 4.72
9 Essential role of phosphoinositide metabolism in synaptic vesicle recycling. Cell 1999 4.70
10 Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis. Nature 1998 4.24
11 Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells. J Cell Biol 1986 3.68
12 Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis. Neuron 1999 3.64
13 Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes. Cell 1998 3.62
14 Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions. Science 1997 3.59
15 A presynaptic inositol-5-phosphatase. Nature 1996 3.54
16 Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes. J Cell Biol 1983 3.49
17 Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain. EMBO J 1989 3.44
18 Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome. N Engl J Med 1990 3.21
19 Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor. Nature 1989 3.17
20 Dynamin and its partners: a progress report. Curr Opin Cell Biol 1998 3.15
21 A functional link between dynamin and the actin cytoskeleton at podosomes. J Cell Biol 2000 3.12
22 The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Proc Natl Acad Sci U S A 1997 3.11
23 The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin. J Cell Biol 1996 3.03
24 Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin. Neuron 2000 2.80
25 Endocytosis and signaling. an inseparable partnership. Cell 2001 2.79
26 GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J 1991 2.69
27 Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. Science 1989 2.61
28 Role of phosphorylation in regulation of the assembly of endocytic coat complexes. Science 1998 2.60
29 Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis. J Cell Biol 1991 2.59
30 Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway. J Cell Biol 1985 2.53
31 The role of Rab3A in neurotransmitter release. Nature 1994 2.48
32 Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells. J Cell Biol 1994 2.46
33 Phosphoinositides in membrane traffic at the synapse. J Cell Sci 2001 2.44
34 Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus. N Engl J Med 1988 2.44
35 Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs. J Cell Biol 1978 2.31
36 The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture. J Neurosci 1991 2.31
37 The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J Biol Chem 1997 2.16
38 Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. EMBO J 1999 2.15
39 PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse. Neuron 2001 2.13
40 Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons. J Cell Biol 1992 2.09
41 A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin. Proc Natl Acad Sci U S A 1994 2.07
42 Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience 1984 2.04
43 Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle. J Cell Biol 1997 2.04
44 Antiamphiphysin antibodies are associated with various paraneoplastic neurological syndromes and tumors. Arch Neurol 1999 2.03
45 rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin. J Cell Biol 1995 2.02
46 Widespread distribution of protein I in the central and peripheral nervous systems. Proc Natl Acad Sci U S A 1979 1.98
47 Membrane fusion machinery: insights from synaptic proteins. Cell 1993 1.96
48 Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer. N Engl J Med 1993 1.95
49 The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module. J Biol Chem 1999 1.91
50 Association of Rab3A with synaptic vesicles at late stages of the secretory pathway. J Cell Biol 1991 1.91
51 Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites. J Biol Chem 2000 1.89
52 Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate. Neuron 1989 1.85
53 Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin. J Neurosci 1995 1.84
54 p145, a major Grb2-binding protein in brain, is co-localized with dynamin in nerve terminals where it undergoes activity-dependent dephosphorylation. J Biol Chem 1994 1.75
55 Synaptophysin is targeted to similar microvesicles in CHO and PC12 cells. EMBO J 1989 1.75
56 Synaptic vesicle endocytosis. Curr Opin Neurobiol 1997 1.71
57 The calcineurin-dynamin 1 complex as a calcium sensor for synaptic vesicle endocytosis. J Biol Chem 1999 1.70
58 Synapsin I in nerve terminals: selective association with small synaptic vesicles. Science 1984 1.67
59 AP-2 recruitment to synaptotagmin stimulated by tyrosine-based endocytic motifs. Science 1999 1.67
60 Markedly elevated GAD antibodies in SPS: effects of age and illness duration. Neurology 2004 1.65
61 Amphiphysin I is associated with coated endocytic intermediates and undergoes stimulation-dependent dephosphorylation in nerve terminals. J Biol Chem 1997 1.63
62 Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of Brefeldin A in axon and dendrites. J Cell Biol 1993 1.60
63 Inositol 1,4,5-trisphosphate receptor causes formation of ER cisternal stacks in transfected fibroblasts and in cerebellar Purkinje cells. Neuron 1994 1.58
64 Dual interaction of synaptotagmin with mu2- and alpha-adaptin facilitates clathrin-coated pit nucleation. EMBO J 2000 1.57
65 Ca2+ stores in Purkinje neurons: endoplasmic reticulum subcompartments demonstrated by the heterogeneous distribution of the InsP3 receptor, Ca(2+)-ATPase, and calsequestrin. J Neurosci 1992 1.55
66 Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF). J Cell Biol 2000 1.55
67 Synapsin I: a synaptic vesicle-associated neuronal phosphoprotein. Biochem Pharmacol 1986 1.54
68 The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals. J Biol Chem 1999 1.49
69 A role for synaptic vesicles in non-neuronal cells: clues from pancreatic beta cells and from chromaffin cells. FASEB J 1994 1.48
70 Disruption of three phosphatidylinositol-polyphosphate 5-phosphatase genes from Saccharomyces cerevisiae results in pleiotropic abnormalities of vacuole morphology, cell shape, and osmohomeostasis. Eur J Cell Biol 1997 1.45
71 Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161. FEBS Lett 1994 1.41
72 Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex. J Cell Biol 1986 1.41
73 Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein. J Neurosci 1994 1.41
74 Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15. FEBS Lett 1997 1.41
75 Synapsins in the vertebrate retina: absence from ribbon synapses and heterogeneous distribution among conventional synapses. Neuron 1990 1.41
76 Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proc Natl Acad Sci U S A 1982 1.40
77 Synaptogenesis in hippocampal cultures: evidence indicating that axons and dendrites become competent to form synapses at different stages of neuronal development. J Neurosci 1994 1.37
78 Differential expression of endophilin 1 and 2 dimers at central nervous system synapses. J Biol Chem 2001 1.36
79 Synaptojanin family members are implicated in endocytic membrane traffic in yeast. J Cell Sci 1998 1.36
80 Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I. Proc Natl Acad Sci U S A 1994 1.35
81 A mammalian guanine-nucleotide-releasing protein enhances function of yeast secretory protein Sec4. Nature 1993 1.34
82 Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain. Proc Natl Acad Sci U S A 1981 1.34
83 Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome. J Exp Med 1993 1.34
84 Localization of Rab5 to synaptic vesicles identifies endosomal intermediate in synaptic vesicle recycling pathway. Eur J Cell Biol 1994 1.32
85 Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2. J Biol Chem 2000 1.31
86 Glutamate regulates actin-based motility in axonal filopodia. Nat Neurosci 2001 1.31
87 Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C. Neuron 1994 1.31
88 Coxsackieviruses and diabetes. Nat Med 1995 1.30
89 Epidermal growth factor pathway substrate 15, Eps15. Int J Biochem Cell Biol 1999 1.29
90 Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells. J Cell Biol 1995 1.28
91 Autoimmunity to glutamic acid decarboxylase (GAD) in Stiff-Man syndrome and insulin-dependent diabetes mellitus. Trends Neurosci 1991 1.26
92 Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix. Eur J Cell Biol 1996 1.25
93 Endocytosis proteins and cancer: a potential link? Trends Cell Biol 1998 1.24
94 Amphiphysin I antisense oligonucleotides inhibit neurite outgrowth in cultured hippocampal neurons. J Neurosci 1998 1.23
95 Association of GAD-65, but not of GAD-67, with the Golgi complex of transfected Chinese hamster ovary cells mediated by the N-terminal region. Proc Natl Acad Sci U S A 1993 1.22
96 Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity. J Biol Chem 2000 1.22
97 Differential effect of alpha-latrotoxin on exocytosis from small synaptic vesicles and from large dense-core vesicles containing calcitonin gene-related peptide at the frog neuromuscular junction. Proc Natl Acad Sci U S A 1988 1.22
98 Autoimmunity to gephyrin in Stiff-Man syndrome. Neuron 2000 1.21
99 The V0 sector of the V-ATPase, synaptobrevin, and synaptophysin are associated on synaptic vesicles in a Triton X-100-resistant, freeze-thawing sensitive, complex. J Biol Chem 1996 1.20
100 Identification and characterization of homologues of the Exocyst component Sec10p. FEBS Lett 1997 1.20
101 Specific interactions of Mss4 with members of the Rab GTPase subfamily. EMBO J 1994 1.19
102 Synaptojanin 1 contributes to maintaining the stability of GABAergic transmission in primary cultures of cortical neurons. J Neurosci 2001 1.19
103 The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling. Nat Cell Biol 2001 1.18
104 Mobility of synaptic vesicles in nerve endings monitored by recovery from photobleaching of synaptic vesicle-associated fluorescence. J Neurosci 1996 1.18
105 Relative properties and localizations of synaptic vesicle protein isoforms: the case of the synaptophysins. J Neurosci 1993 1.18
106 P29: a novel tyrosine-phosphorylated membrane protein present in small clear vesicles of neurons and endocrine cells. J Cell Biol 1990 1.18
107 Synaptotagmin: a membrane constituent of neuropeptide-containing large dense-core vesicles. J Neurosci 1993 1.17
108 Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction. J Cell Biol 1990 1.16
109 Yeast protein translocation complex: isolation of two genes SEB1 and SEB2 encoding proteins homologous to the Sec61 beta subunit. Yeast 1996 1.16
110 Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas. Nature 1979 1.14
111 Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase. J Biol Chem 1995 1.14
112 Chronic blockade of glutamate receptors enhances presynaptic release and downregulates the interaction between synaptophysin-synaptobrevin-vesicle-associated membrane protein 2. J Neurosci 2001 1.14
113 Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals. J Biol Chem 2001 1.14
114 Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze-fracture study. J Cell Biol 1976 1.11
115 Cellular and subcellular localization of protein I in the peripheral nervous system. Proc Natl Acad Sci U S A 1982 1.09
116 Alzheimer amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway. J Biol Chem 1996 1.08
117 Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve terminals. J Cell Biol 1989 1.06
118 Anatomy of cerebellar Purkinje cells in the rat determined by a specific immunohistochemical marker. Neuroscience 1984 1.04
119 Anti-amphiphysin I antibodies in patients with paraneoplastic neurological disorders associated with small cell lung carcinoma. J Neurol Neurosurg Psychiatry 1999 1.03
120 Localization of synapsin I at the frog neuromuscular junction. Neuroscience 1988 1.03
121 A signal located within amino acids 1-27 of GAD65 is required for its targeting to the Golgi complex region. J Cell Biol 1994 1.02
122 Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity. Proc Natl Acad Sci U S A 1997 1.02
123 Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis. J Biol Chem 1998 1.01
124 Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. Mol Med 1998 0.97
125 Differential expression of synapsins I and II among rat retinal synapses. J Neurosci 1992 0.97
126 Structural difference between luminal and lateral plasmalemma in pancreatic acinar cells. Nature 1974 0.96
127 v- and t-SNAREs in neuronal exocytosis: a need for additional components to define sites of release. Neuropharmacology 1995 0.95
128 Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons. J Neurosci 1999 0.94
129 InsP3 receptor turnaround. Nature 1990 0.94
130 A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells. Proc Natl Acad Sci U S A 1993 0.93
131 Interactions of dynamin and amphiphysin with liposomes. Methods Enzymol 2001 0.92
132 Membrane interactions between secretion granules and plasmalemma in three exocrine glands. J Cell Biol 1980 0.90
133 Exocytosis goes with a SNAP. Nature 1993 0.89
134 Mechanisms of synaptogenesis in hippocampal neurons in primary culture. J Physiol Paris 1995 0.88
135 Calcium dependence of synaptic vesicle recycling before and after synaptogenesis. J Neurochem 1998 0.88
136 Synaptophysin immunoreactivity and small clear vesicles in neuroendocrine cells and related tumours. Mol Cell Probes 1987 0.88
137 A novel mammalian guanine nucleotide exchange factor (GEF) specific for rab proteins. Adv Second Messenger Phosphoprotein Res 1994 0.88
138 Emergence of cyclic guanosine 3':5'-monophosphate-dependent protein kinase immunoreactivity in developing rhesus monkey cerebellum: correlative immunocytochemical and electron microscopic analysis. J Neurosci 1984 0.87
139 Sudden death and paroxysmal autonomic dysfunction in stiff-man syndrome. J Neurol 1991 0.87
140 Presence of synapsin I in afferent and efferent nerve endings of vestibular sensory epithelia. Brain Res 1986 0.86
141 Molecular mechanisms in neurotransmitter release. Curr Opin Neurobiol 1991 0.86
142 Formation of synaptic vesicles. Curr Opin Cell Biol 1994 0.86
143 Autoimmunity to beta IV spectrin in paraneoplastic lower motor neuron syndrome. Proc Natl Acad Sci U S A 2001 0.85
144 A radioimmunoassay to monitor synaptic activity in hippocampal neurons in vitro. Eur J Cell Biol 1995 0.85
145 Traffic of synaptic vesicle proteins in polarized and nonpolarized cells. J Cell Sci Suppl 1993 0.84
146 Molecular mechanisms in synaptic vesicle recycling. J Neurocytol 1996 0.83
147 Type II cAMP-dependent protein kinase regulatory subunit-binding proteins. Methods Enzymol 1988 0.83
148 Synaptic targeting domains of synapsin I revealed by transgenic expression in photoreceptor cells. EMBO J 1994 0.83
149 Specificity of the binding of synapsin I to Src homology 3 domains. J Biol Chem 2000 0.83
150 Secretory function of the vestibular nerve calyx suggested by presence of vesicles, synapsin I, and synaptophysin. J Neurosci 1988 0.82
151 Secretory organelles of neurons and their relationship to organelles of other cells. Cell Biol Int Rep 1989 0.81
152 Membrane interactions in secretory cell systems. Symp Soc Exp Biol 1979 0.80
153 Substance P-like immunoreactivity at the frog neuromuscular junction. Neuroscience 1990 0.79
154 Association of HLA-DQB1*0201 with stiff-man syndrome. J Clin Endocrinol Metab 1993 0.79
155 Immunohistochemical localization of secretogranin II in the rat cerebellum. Neuroscience 1989 0.79
156 Assignment of SYNJ1 to human chromosome 21q22.2 and Synj12 to the murine homologous region on chromosome 16C3-4 by in situ hybridization. Cytogenet Cell Genet 2000 0.79
157 GAD, diabetes, and Stiff-Man syndrome: some progress and more questions. J Endocrinol Invest 1995 0.78
158 A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer. Neurology 1999 0.78
159 Subcellular distribution of the PI effect in the pancreas of the guinea pig. Life Sci 1974 0.77
160 Diabetes. Spotlight on a neuronal enzyme. Nature 1993 0.77
161 The effect of extracellular calcium on the topological organization of the plasmalemma in two secretory systems. Ann N Y Acad Sci 1978 0.77
162 Neurotransmission. Keeping synapses up to speed. Nature 1995 0.77
163 Recycling of synaptic vesicles. Adv Pharmacol 1998 0.77
164 Genetics of susceptibility and resistance to insulin-dependent diabetes in stiff-man syndrome. Lancet 1994 0.77
165 Molecular mechanisms in synaptic vesicle endocytosis. Cold Spring Harb Symp Quant Biol 1995 0.76
166 The stimulatory effect of rabphilin 3a on regulated exocytosis from insulin-secreting cells does not require an association-dissociation cycle with membranes mediated by Rab 3. Eur J Cell Biol 1997 0.76
167 Intraneuronal trafficking and distribution of amphiphysin and synaptojanin in the rat peripheral nervous system and the spinal cord. Eur J Neurosci 1997 0.75
168 Synaptic autoimmunity and the Salk factor. Neuron 2000 0.75
169 From Th1 to Th2: diabetes immunotherapy shifts gears. Nat Med 1996 0.75
170 Studies on rat pituitary homografts. I. In vitro biosynthesis and release of growth hormone and prolactin. Endocrinology 1979 0.75
171 Paraneoplastic stiff-person syndrome: no tumor progression over 5 years. Neurology 2002 0.75
172 Expression, purification, and functional assay of Mss4. Methods Enzymol 1995 0.75
173 Immunocytochemistry as a tool in the study of protein phosphorylation in the nervous system. Adv Cyclic Nucleotide Protein Phosphorylation Res 1984 0.75
174 Membrane events during stimulated exocytosis in exocrine glands [proceedings]. J Physiol 1978 0.75
175 [Demonstration and localization of synapsin I in vestibular receptors in the cat: immunocytochemical study]. C R Acad Sci III 1986 0.75