PubRank

Y Haupt

Author PubWeight™ 32.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 c-Jun and p53 activity is modulated by SUMO-1 modification. J Biol Chem 2000 2.71
2 Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J 1999 2.64
3 The cellular response to p53: the decision between life and death. Oncogene 1999 2.31
4 A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res 1995 2.23
5 Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J 1996 2.12
6 A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol Cell Biol 1996 1.98
7 Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene 1999 1.56
8 The Mdm2 oncoprotein interacts with the cell fate regulator Numb. Mol Cell Biol 1998 1.53
9 AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy. Oncogene 2011 1.45
10 E6AP promotes the degradation of the PML tumor suppressor. Cell Death Differ 2009 1.24
11 A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J 1997 1.24
12 c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination. Mol Cell Biol 2001 1.19
13 Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53. Oncogene 2001 1.15
14 c-Abl neutralizes the inhibitory effect of Mdm2 on p53. J Biol Chem 1999 1.09
15 Tumor suppressor p53 regulates heparanase gene expression. Oncogene 2006 1.07
16 PML enhances the regulation of p53 by CK1 in response to DNA damage. Oncogene 2008 1.05
17 A role for the polyproline domain of p53 in its regulation by Mdm2. J Biol Chem 2000 1.01
18 Clues from worms: a Slug at Puma promotes the survival of blood progenitors. Cell Death Differ 2006 0.88
19 Interplay between p53 and VEGF: how to prevent the guardian from becoming a villain. Cell Death Differ 2013 0.81
20 Apoptosis by p53: mechanisms, regulation, and clinical implications. Springer Semin Immunopathol 1998 0.79
21 p53 controls hPar1 function and expression. Oncogene 2008 0.79
22 E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts. Oncogene 2011 0.77
23 p53 and thymic 'death by neglect': thymic epithelial cell-induced apoptosis of CD4+8+ thymocytes is p53-independent. Cell Death Differ 2000 0.77
24 The E6AP E3 ubiquitin ligase regulates the cellular response to oxidative stress. Oncogene 2012 0.76
25 Stimulating p53 down-under: a report from the 1st Australian p53 Workshop. Cell Death Differ 2013 0.75