J H Krystal

Author PubWeight™ 126.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000 10.91
2 Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc Natl Acad Sci U S A 1996 3.28
3 Measurement of dissociative states with the Clinician-Administered Dissociative States Scale (CADSS). J Trauma Stress 1998 3.07
4 Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists. Arch Gen Psychiatry 2000 2.92
5 Abnormal noradrenergic function in posttraumatic stress disorder. Arch Gen Psychiatry 1993 2.89
6 Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch Gen Psychiatry 1999 2.78
7 A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry 2001 2.58
8 Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am J Psychiatry 1997 2.22
9 Clinical phenomenology and neurobiology of cocaine abstinence: a prospective inpatient study. Am J Psychiatry 1991 2.17
10 Report of the Institute of Medicine Committee on the Efficacy and Safety of Halcion. Arch Gen Psychiatry 1999 2.03
11 Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies. Synapse 1996 1.97
12 Psychobiologic mechanisms of posttraumatic stress disorder. Arch Gen Psychiatry 1993 1.88
13 Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Preliminary observations. Arch Gen Psychiatry 1989 1.86
14 Activation of human prefrontal cortex during spatial and nonspatial working memory tasks measured by functional MRI. Cereb Cortex 1996 1.82
15 Noradrenergic mechanisms in stress and anxiety: II. Clinical studies. Synapse 1996 1.75
16 Toward a neurobiology of delusions. Prog Neurobiol 2010 1.70
17 Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. Arch Gen Psychiatry 1990 1.56
18 Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. Am J Psychiatry 1993 1.56
19 First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients. Mol Psychiatry 2006 1.49
20 Clinical and medication outcome after short-term alprazolam and behavioral group treatment in panic disorder. 2.5 year naturalistic follow-up study. Arch Gen Psychiatry 1989 1.47
21 Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Arch Gen Psychiatry 2001 1.43
22 Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology. Mol Psychiatry 2012 1.41
23 Rapid detoxification from opioid dependence. Am J Psychiatry 1989 1.40
24 Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates. J Neurosci 1990 1.34
25 Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans. Mol Psychiatry 2013 1.31
26 Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. Arch Gen Psychiatry 1997 1.31
27 Quantitative morphology of the caudate and putamen in patients with cocaine dependence. Am J Psychiatry 2001 1.30
28 NMDA receptor regulation of memory and behavior in humans. Hippocampus 2001 1.30
29 Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices". Biol Psychiatry 1999 1.25
30 Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry 1999 1.25
31 Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action. Biol Psychiatry 1999 1.20
32 Neuroleptic addition in fluvoxamine-refractory obsessive-compulsive disorder. Am J Psychiatry 1990 1.17
33 Transcranial magnetic stimulation and auditory hallucinations in schizophrenia. Lancet 2000 1.16
34 The NMDA antagonist model for schizophrenia: promise and pitfalls. Pharmacopsychiatry 1998 1.14
35 Impairment of GABAergic transmission in depression: new insights from neuroimaging studies. Crit Rev Neurobiol 2000 1.13
36 Functional neuroanatomical correlates of the effects of stress on memory. J Trauma Stress 1995 1.12
37 Dissociation of mnemonic and perceptual processes during spatial and nonspatial working memory using fMRI. Hum Brain Mapp 1998 1.11
38 Complications of alcohol withdrawal: pathophysiological insights. Alcohol Health Res World 1998 1.11
39 Multiple mechanisms of withdrawal from opioid drugs. Annu Rev Neurosci 1984 1.10
40 Neurotransmitter alterations in PTSD: catecholamines and serotonin. Semin Clin Neuropsychiatry 1999 1.08
41 Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Arch Gen Psychiatry 1997 1.08
42 Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Arch Gen Psychiatry 1996 1.08
43 Noradrenergic and serotonergic function in posttraumatic stress disorder. Arch Gen Psychiatry 1997 1.05
44 Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation. Semin Clin Neuropsychiatry 1999 1.05
45 IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans. Biol Psychiatry 2000 1.03
46 Ethanol-like effects of thiopental and ketamine in healthy humans. J Psychopharmacol 2008 0.97
47 Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. J Neuropsychiatry Clin Neurosci 1996 0.97
48 Noradrenergic neuronal dysregulation in panic disorder: the effects of intravenous yohimbine and clonidine in panic disorder patients. Acta Psychiatr Scand 1992 0.96
49 Neurobiological correlates of the disposition and maintenance of alcoholism. Pharmacopsychiatry 2003 0.96
50 Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients. Am J Psychiatry 1993 0.95
51 Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology (Berl) 2012 0.92
52 Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia. Schizophr Res 1991 0.91
53 Opioid antagonist challenges in buprenorphine maintained patients. Drug Alcohol Depend 1990 0.91
54 Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression. Psychopharmacol Bull 1991 0.90
55 Lack of behavioral effects of monoamine depletion in healthy subjects. Biol Psychiatry 1997 0.90
56 Lamotrigine in the treatment of depersonalization disorder. J Clin Psychiatry 2001 0.89
57 Excitatory amino acids and morphine withdrawal: differential effects of central and peripheral kynurenic acid administration. Psychopharmacology (Berl) 1991 0.88
58 Yohimbine-facilitated acoustic startle reflex in humans. Psychopharmacology (Berl) 1993 0.88
59 Affective reactivity of language in schizophrenia. J Nerv Ment Dis 1994 0.88
60 Serotonin function and human anxiety disorders. Ann N Y Acad Sci 1990 0.87
61 Effects of rapid tryptophan depletion in patients with seasonal affective disorder in remission after light therapy. Arch Gen Psychiatry 1996 0.87
62 Noradrenergic alterations in posttraumatic stress disorder. Ann N Y Acad Sci 1997 0.86
63 Mazindol treatment for cocaine dependence. Drug Alcohol Depend 1995 0.86
64 Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry 1995 0.86
65 Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology. Mol Psychiatry 2012 0.86
66 Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil. Am J Psychiatry 1998 0.85
67 [123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia. Psychiatry Res 1999 0.85
68 Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists. Neuropsychopharmacology 2001 0.85
69 Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biol Psychiatry 1997 0.84
70 Yohimbine facilitated acoustic startle in combat veterans with post-traumatic stress disorder. Psychopharmacology (Berl) 1995 0.84
71 Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology (Berl) 2001 0.84
72 Naltrexone augmentation of neuroleptics in schizophrenia. J Clin Psychopharmacol 1998 0.84
73 Recurrent self-injurious behavior in forensic patients. Psychiatr Q 1996 0.84
74 Assessment of alexithymia in posttraumatic stress disorder and somatic illness: introduction of a reliable measure. Psychosom Med 1986 0.84
75 Neural mechanisms in dissociative amnesia for childhood abuse: relevance to the current controversy surrounding the "false memory syndrome". Am J Psychiatry 1996 0.84
76 Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation. Biol Psychiatry 2001 0.83
77 Serotonin-specific drugs for anxiety and depressive disorders. Annu Rev Med 1990 0.83
78 Clinical predictors of self-mutilation in hospitalized forensic patients. J Nerv Ment Dis 1994 0.83
79 Effects of tryptophan depletion on responses to yohimbine in healthy human subjects. Biol Psychiatry 1995 0.82
80 Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans. Eur J Pharmacol 1999 0.81
81 Effects of cocaine on hospital course in schizophrenia. J Nerv Ment Dis 1993 0.81
82 Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus. Mol Psychiatry 2004 0.81
83 SPECT regional cerebral blood flow and neuropsychological testing in non-demented HIV-positive drug abusers: preliminary results. Prog Neuropsychopharmacol Biol Psychiatry 1991 0.80
84 Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology (Berl) 1995 0.80
85 Prolonged postictal encephalopathy in two patients with clozapine-induced seizures. J Neuropsychiatry Clin Neurosci 1992 0.80
86 Symptom provocation studies in psychiatric disorders: scientific value, risks, and future. Biol Psychiatry 1999 0.80
87 Psychobiologic research in post-traumatic stress disorder. Psychiatr Clin North Am 1994 0.80
88 Noradrenergic function in panic disorder. J Clin Psychiatry 1990 0.79
89 Effects of sleep deprivation on serotonin function in depression. Biol Psychiatry 1994 0.79
90 A preliminary description of acute physical dependence on morphine in the vervet monkey. Pharmacol Biochem Behav 1983 0.78
91 Clinical studies of 5-HT function using i.v. L-tryptophan. Prog Neuropsychopharmacol Biol Psychiatry 1990 0.78
92 Behavioral, biochemical, and cardiovascular responses to the benzodiazepine receptor antagonist flumazenil in panic disorder. Psychiatry Res 1991 0.77
93 Effect of tryptophan depletion on alcohol cue-induced craving in abstinent alcoholic patients. Alcohol Clin Exp Res 2001 0.77
94 D-serine and the therapeutic challenge posed by the N-methyl-D-aspartate antagonist model of schizophrenia. Biol Psychiatry 1998 0.77
95 Long-term outcome of panic disorder after short-term imipramine and behavioral group treatment: 2.9-year naturalistic follow-up study. J Clin Psychopharmacol 1993 0.77
96 Effects of the benzodiazepine antagonist flumazenil in PTSD. Biol Psychiatry 1995 0.77
97 Continuous intravenous infusion of iodine-123-IBZM for SPECT determination of human brain dopamine receptor occupancy by antipsychotic agent RWJ-37796. J Nucl Med 1996 0.77
98 Visual stimulation increases technetium-99m-HMPAO distribution in human visual cortex. J Nucl Med 1991 0.77
99 Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects. Psychiatry Res 1991 0.76
100 Comment on "Ketamine has equal affinity for NMDA receptors and the high-affinity state of the dopamine D(2) receptor". Biol Psychiatry 2001 0.75
101 SPECT regional cerebral blood flow alterations in naltrexone-precipitated withdrawal from buprenorphine. Psychiatry Res 1994 0.75
102 A review of behavioral and pharmacologic studies relevant to the application of CO2 as a human subject model of anxiety. Psychopharmacol Bull 1988 0.75
103 Precipitation of a psychoneuromotor syndrome by fluoxetine in a haloperidol-treated schizophrenic patient. J Clin Psychopharmacol 1994 0.75
104 Marijuana (cannabis) use is anecdotally said to precipitate anxiety symptoms in patients with panic disorder. Is there any research evidence to support this? Also, can marijuana use precipitate or expose paranoia in patients with an underlying bipolar disorder? J Clin Psychopharmacol 1990 0.75
105 Discontinuing anticonvulsant treatment of aggression. J Neuropsychiatry Clin Neurosci 1995 0.75
106 Responses to i.v. L-tryptophan in MDMA users. NIDA Res Monogr 1989 0.75
107 Mazindol and cocaine addiction in schizophrenia. Biol Psychiatry 1992 0.75
108 CSF monoamine metabolite and beta endorphin levels in recently detoxified alcoholics and healthy controls: prediction of alcohol cue-induced craving? Alcohol Clin Exp Res 1999 0.75
109 Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder. J Clin Psychopharmacol 1992 0.75
110 Short-term use of disulfiram with clozapine. J Clin Psychopharmacol 1994 0.75
111 Effects of alprazolam and clonidine on carbon dioxide-induced increases in anxiety ratings in healthy human subjects. Life Sci 1989 0.75
112 Use of yohimbine to counteract nortriptyline-induced orthostatic hypotension. J Clin Psychopharmacol 1989 0.75
113 Creatine kinase elevations and aggressive behavior in hospitalized forensic patients. Psychiatr Q 1998 0.75
114 Clinical data on the role of serotonin in the mechanism(s) of action of antidepressant drugs. J Clin Psychiatry 1990 0.75
115 Valproate management of psychosis in a patient with carbamazepine-induced hyponatremia. J Clin Psychopharmacol 1992 0.75