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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 1994 5.49
2 Recombinant glycoprotein vaccine for the prevention of genital HSV-2 infection: two randomized controlled trials. Chiron HSV Vaccine Study Group. JAMA 1999 4.91
3 Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 1999 2.78
4 Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. JAMA 1995 2.71
5 Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma. Blood 1999 2.10
6 An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science 2000 2.03
7 Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nat Med 1998 1.79
8 Immune responses to AAV in a phase I study for Canavan disease. J Gene Med 2006 1.74
9 Patients attending STD clinics in an evolving health care environment. Demographics, insurance coverage, preferences for STD services, and STD morbidity. Sex Transm Dis 1997 1.69
10 Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies. J Pharmacol Exp Ther 1993 1.38
11 Elevations of nucleus accumbens dopamine and DOPAC levels during intravenous heroin self-administration. Synapse 1995 1.34
12 Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes. Gene Ther 2001 1.34
13 Delayed presentation to clinics for sexually transmitted diseases by symptomatic patients. A potential contributor to continuing STD morbidity. Sex Transm Dis 1997 1.27
14 Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P). Vaccine 2001 1.26
15 Porokeratosis--a mutant clonal keratosis of the epidermis. I. Histogenesis. Arch Dermatol 1970 1.24
16 Weight loss in postmenopausal obesity: no adverse alterations in body composition and protein metabolism. Am J Physiol Endocrinol Metab 2000 1.20
17 Concordance of chlamydia trachomatis infections within sexual partnerships. Sex Transm Infect 2007 1.16
18 In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Ther 1998 1.16
19 Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels. J Clin Invest 1995 1.13
20 The effect of leptin is enhanced by microinjection into the ventromedial hypothalamus. Diabetes 1997 1.09
21 Effects of a flexibility and relaxation programme, walking, and nordic walking on Parkinson's disease. J Aging Res 2011 1.06
22 Activation of matrix-metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability in vivo by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor. Mol Biol Cell 2001 1.06
23 Alpha interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cells. J Virol 1999 1.04
24 Verrucous lesion in patients with discoid lupus erythematosus. Clinical, histopathological and immunofluorescence studies. Br J Dermatol 1978 1.02
25 Long range restriction analysis of the bovine casein genes. Nucleic Acids Res 1990 1.01
26 Prevalence, incidence and correlates of HHV-8/KSHV infection and Kaposi's sarcoma in renal and liver transplant recipients. J Infect 2001 1.00
27 Identification and characterization of novel mutations of the aspartoacylase gene in non-Jewish patients with Canavan disease. J Inherit Metab Dis 2002 0.99
28 Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in skeletal muscle. J Clin Invest 1995 0.97
29 SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade? Psychopharmacology (Berl) 1989 0.96
30 Angiopoietin 2 concentrations in infants developing bronchopulmonary dysplasia: attenuation by dexamethasone. J Perinatol 2007 0.95
31 Direct measurement of extracellular lactate in the human hippocampus during spontaneous seizures. J Neurochem 1994 0.94
32 Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI. Neuropediatrics 2006 0.94
33 Chromosomal localization and molecular characterization of 53 cosmid-derived bovine microsatellites. Mamm Genome 1995 0.93
34 Viral-based gene transfer to the mammalian CNS for functional genomic studies. Trends Neurosci 2001 0.90
35 5-HT3 receptor antagonists block morphine- and nicotine-induced place-preference conditioning. Eur J Pharmacol 1988 0.89
36 Effects of AAV-2-mediated aspartoacylase gene transfer in the tremor rat model of Canavan disease. Brain Res Mol Brain Res 2005 0.89
37 Mesolimbic dopamine neurotransmission is increased by administration of mu-opioid receptor antagonists. Eur J Pharmacol 1993 0.88
38 Ventral tegmental area opioid mechanisms and modulation of ingestive behavior. Brain Res 1995 0.88
39 Dual infection with different strains of the same HIV-1 subtype. AIDS 1997 0.88
40 5HT3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward. Psychopharmacology (Berl) 1989 0.88
41 Human intrathecal transplantation of peripheral blood stem cells in amyotrophic lateral sclerosis. J Hematother Stem Cell Res 2001 0.88
42 Overexpression of GluR6 in rat hippocampus produces seizures and spontaneous nonsynaptic bursting in vitro. Neurobiol Dis 2000 0.85
43 Transverse changes determined by rapid and slow maxillary expansion--a low-dose CT-based randomized controlled trial. Orthod Craniofac Res 2012 0.85
44 Blockade of D-1 receptors by SCH 23390 antagonizes morphine- and amphetamine-induced place preference conditioning. Eur J Pharmacol 1987 0.82
45 Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy. Epilepsia 1997 0.81
46 Aspergilloma: an unusual cause of late failure of aortocoronary bypass graft. Chest 1973 0.81
47 Substrate characterization for underwater gamma spectrometry: tank measurement results utilizing efficiencies calculated via Monte-Carlo code. Appl Radiat Isot 2004 0.81
48 Ventral mesencephalic delta opioid receptors are involved in modulation of basal mesolimbic dopamine neurotransmission: an anatomical localization study. Brain Res 1993 0.80
49 Adeno-associated virus vectors for gene therapy of neurodegenerative disorders. Clin Neurosci 1997 0.80
50 Hepatitis B virus mother-to-child transmission among HIV-infected women receiving lamivudine-containing antiretroviral regimens during pregnancy and breastfeeding. J Viral Hepat 2014 0.79
51 5-HT3 receptors antagonists block morphine- and nicotine- but not amphetamine-induced place-preference conditioning. Pharmacol Res Commun 1988 0.79
52 Targets for gene therapy of Parkinson's disease: growth factors, signal transduction, and promoters. Exp Neurol 1997 0.79
53 Lytic growth of human herpesvirus 8: morphological aspects. Ultrastruct Pathol 2001 0.78
54 Rapid detection of three large novel deletions of the aspartoacylase gene in non-Jewish patients with Canavan disease. Mol Genet Metab 2006 0.78
55 Selective inhibition of trypsins by insect peptides: role of P6-P10 loop. Biochemistry 2003 0.78
56 Direct characterization of bovine microsatellites from cosmids: polymorphism and synteny mapping. Anim Genet 1994 0.77
57 Genetic analysis of metamorphic and premetamorphic Xenopus ciliary marginal zone. Dev Dyn 2005 0.77
58 Molecular abnormalities of chromosome-19 in malignant gliomas - preferential involvement of the 19q13.2-q13.4 region. Int J Oncol 1995 0.77
59 Intra-VTA injections of the mu-opioid antagonist CTOP enhance locomotor activity. Brain Res 1995 0.76
60 Polyamines found in the inflamed periodontium inhibit priming and apoptosis in human polymorphonuclear leukocytes. J Periodontol 1999 0.76
61 Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy. Exp Neurol 1997 0.76
62 Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea. Trovafloxacin Gonorrhea Study Group. Am J Med 1998 0.75
63 Striatal tissue preparation facilitates early sampling in microdialysis and reveals an index of neuronal damage. J Neurochem 1993 0.75
64 [Serum aldolase and creatine phosphokinase in progressive muscular dystrophy]. Clin Pediatr (Bologna) 1967 0.75
65 [Preliminary observations on the incidence of respiratory syncytial virus infection in acute respiratory diseases in childhood. Statistics of the Pediatric Clinic, November 1967-April 1968]. Riv Clin Pediatr 1970 0.75
66 [The Stellenbosch triangle in three-dimensional cephalometric analysis]. Arch Stomatol (Napoli) 1988 0.75
67 [Immunotherapy in the management of metastatic renal carcinoma]. Minerva Urol Nefrol 2002 0.75
68 [Virological and serological studies of a series of cases of acute respiratory infections of pediatric age and of a control group]. Riv Ist Sieroter Ital 1970 0.75
69 Extended colonic lymphangiomatosis. Computed tomographic colonography in addition to optical endoscopy. Minerva Chir 2009 0.75
70 [Postprostatectomy erectile dysfunction]. Minerva Urol Nefrol 2001 0.75
71 [On 3 cases of congenital hypothyroidism with lingual ectopic thyroid]. Clin Pediatr (Bologna) 1969 0.75
72 [Stenosis of the new bladder neck, a complication of radical prostatectomy: personal experience]. Minerva Urol Nefrol 2002 0.75
73 Primary effusion lymphoma cells undergoing human herpesvirus type 8 productive infection produce C-type retroviral particles. Int J Immunopathol Pharmacol 2009 0.75
74 [On spontaneous pneumothorax due to neoplastic metastasis in the lung]. Rass Int Clin Ter 1967 0.75
75 [Primary absolute anorgasmy in the male. Report of three clinical cases]. Minerva Urol Nefrol 1999 0.75
76 Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-alpha therapy: a case report. Clin Infect Dis 2001 0.75
77 [The destroyed lung. Findings concerning cardiovascular physiopathology]. Arch Tisiol Mal Appar Respir 1968 0.75
78 Construction of a library of bovine genomic fragments enriched in CpG islands. Anim Genet 1993 0.75
79 Gamma knife radiosurgery in brain metastases from testicular tumors. Med Oncol 2005 0.75
80 Adenocarcinoma of kidney implicated by urinary cytologic study. Urology 1975 0.75
81 Hospice contracted service arrangements: pitfalls and potential. Caring 1985 0.75
82 [Control of the time of recovery from pulmonary tuberculosis obtained with specific antimycobacterial therapy alone]. Lotta Tuberc 1972 0.75
83 [Rothmund-Thomson syndrome (histochemical, biochemical and radiographical findings)]. Arch Ital Pediatr Pueric 1971 0.75
84 [The pulmonary-venous complex: behavior of the functional and anatomical component in certain pathologic conditions of the respiratory system]. Arch Tisiol Mal Appar Respir 1967 0.75
85 [On primary malignant tumors of the pleura (clinico-radiological contribution)]. Arch Tisiol Mal Appar Respir 1967 0.75
86 [Clinical and hematological considerations on a case of chronic juvenile myeloid leukemia]. Minerva Pediatr 1969 0.75
87 [Aspects of ventilatory physio-mechanics in evaluation of functional damage caused by destroyed lung]. Arch Tisiol Mal Appar Respir 1968 0.75
88 [Clinico-hematological considerations on a case of juvenile chronic myeloid leukemia]. Minerva Pediatr 1969 0.75
89 Genetic variation and distances of five Italian native sheep breeds. Anim Genet 1990 0.75
90 [On a case of eosinophilic granuloma]. Minerva Pediatr 1970 0.75
91 Long-term evaluation of cellular immunity during antiretroviral therapy and immunization with human immunodeficiency virus type 1 (HIV-1) Env glycoprotein in HIV-1-infected persons. J Infect Dis 1997 0.75
92 [Carbohydrate separation by thin-layer chromatography]. Riv Clin Pediatr 1971 0.75
93 [Clinical aspects of pulmonary tuberculosis in the first 20 years of life]. Arch Tisiol Mal Appar Respir 1967 0.75
94 Orthodontic finalization strategies in dysfunctional adult patients. Cranio 2001 0.75
95 [The treatment of progressive muscular dystrophy with nucleosides and nucleotides. Clinical and serologic findings (aldolase and creatinphosphokinase)]. Clin Pediatr (Bologna) 1967 0.75
96 Single-dose gatifloxacin compared with ofloxacin for the treatment of uncomplicated gonorrhea: a randomized, double-blind, multicenter trial. Sex Transm Dis 2001 0.75
97 Affective differences among undergraduate students. Ment Retard 1977 0.75
98 [Analysis of urine carbohydrates by thin-layer chromatography]. Riv Clin Pediatr 1971 0.75
99 Direct sequencing and bidirectional allele specific polymerase chain reaction of the bovine beta-casein B variant. Anim Genet 1992 0.75
100 [Cellular enzymes and mongolism. Study on the glucose-6-phosphate dehydrogenase erythrocytes activity]. Minerva Pediatr 1969 0.75
101 [Studies of tuberculosis in the first 12 years of life in subjects with initially detected in the Centro Diagnostico dell'Istitute Principi di Piemonte di Napoli]. Arch Tisiol Mal Appar Respir 1967 0.75