Leishmania-specific T cells expressing interferon-gamma (IFN-gamma) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMC 1905302)

Published in Clin Exp Immunol on June 01, 1999

Authors

K Kemp1, M Kemp, A Kharazmi, A Ismail, J A Kurtzhals, L Hviid, T G Theander

Author Affiliations

1: Centre for Medical Parasitology at Laboratory Centre and RHIMA Centre, Copenhagen University Hospital (Rigshospitalet), Denmark. kkcmp@rh.dk

Articles citing this

Regulation of adaptive immunity; the role of interleukin-10. Front Immunol (2013) 1.38

Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil. Genes Immun (2006) 1.08

Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo. Vet Res (2008) 1.05

Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination. Infect Immun (2002) 1.00

IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog (2012) 1.00

Evaluation of ex vivo human immune response against candidate antigens for a visceral leishmaniasis vaccine. Am J Trop Med Hyg (2010) 0.93

Evaluation of Leishmania donovani protein disulfide isomerase as a potential immunogenic protein/vaccine candidate against visceral Leishmaniasis. PLoS One (2012) 0.87

Biomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications. Front Immunol (2014) 0.82

Evaluation of nephroprotective and immunomodulatory activities of antioxidants in combination with cisplatin against murine visceral leishmaniasis. PLoS Negl Trop Dis (2012) 0.81

Identification of Leishmania donovani antigens stimulating cellular immune responses in exposed immune individuals. Clin Exp Immunol (2006) 0.80

One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis. BMC Vet Res (2015) 0.78

Immunostimulatory properties of dendritic cells after Leishmania donovani infection using an in vitro model of liver microenvironment. PLoS Negl Trop Dis (2010) 0.78

Immunoprotective responses of T helper type 1 stimulatory protein-S-adenosyl-L-homocysteine hydrolase against experimental visceral leishmaniasis. Clin Exp Immunol (2016) 0.75

Glycyrrhizic Acid-Mediated Subdual of Myeloid-Derived Suppressor Cells Induces Antileishmanial Immune Responses in a Susceptible Host. Infect Immun (2015) 0.75

Articles cited by this

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 16.28

Detection of intracellular cytokines by flow cytometry. J Immunol Methods (1993) 4.54

Human TH1 and TH2 subsets: doubt no more. Immunol Today (1991) 3.81

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods (1995) 3.54

Absence of gamma interferon and interleukin 2 production during active visceral leishmaniasis. J Clin Invest (1985) 3.41

Interleukin 10 production correlates with pathology in human Leishmania donovani infections. J Clin Invest (1993) 3.28

New perspectives on a subclinical form of visceral leishmaniasis. J Infect Dis (1986) 2.92

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. J Clin Invest (1993) 2.84

Th1-Th2: reliable paradigm or dangerous dogma? Immunol Today (1997) 2.83

An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci U S A (1997) 2.67

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10. J Exp Med (1996) 2.36

Th1 and Th2 subsets: paradigms lost? Immunol Today (1995) 2.21

Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis. J Immunol (1991) 2.00

IL-12 enhances Th1-type responses in human Leishmania donovani infections. J Immunol (1995) 1.69

Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J Immunol (1998) 1.53

Potential role for interleukin-10 in the immunosuppression associated with kala azar. J Clin Invest (1993) 1.47

IL-12 induces human T cells secreting IL-10 with IFN-gamma. J Immunol (1996) 1.32

A new portable device for automatic controlled-gradient cryopreservation of blood mononuclear cells. J Immunol Methods (1993) 1.29

Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis. Clin Exp Immunol (1994) 1.16

Recognition of Leishmania antigens by T lymphocytes from nonexposed individuals. Infect Immun (1992) 1.13

In vivo and in vitro cytokine profiles and mononuclear cell subsets in Sicilian patients with active visceral leishmaniasis. Cytokine (1995) 1.13

Measurement of intracellular cytokines. Immunol Today (1996) 1.12

The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example. Immunol Today (1996) 1.10

Dichotomy of the human T cell response to Leishmania antigens. II. Absent or Th2-like response to gp63 and Th1-like response to lipophosphoglycan-associated protein in cells from cured visceral leishmaniasis patients. Clin Exp Immunol (1994) 1.08

Interferon-gamma production by human T cells and natural killer cells in vitro in response to antigens from the two intracellular pathogens Mycobacterium tuberculosis and Leishmania major. Scand J Immunol (1997) 0.93

Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections. Clin Exp Immunol (1995) 0.92

Interleukin-4 and interferon-gamma production by Leishmania stimulated peripheral blood mononuclear cells from nonexposed individuals. Scand J Immunol (1995) 0.89

Production of interferon-gamma and interleukin-4 by human T cells recognizing Leishmania lipophosphoglycan-associated protein. Immunol Lett (1993) 0.82

Interferon-gamma and interleukin-4 production by human T cells recognizing Leishmania donovani antigens separated by SDS-PAGE. APMIS (1995) 0.81

Articles by these authors

Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A. J Immunol (2000) 3.74

Excretion of ciprofloxacin in sweat and multiresistant Staphylococcus epidermidis. Lancet (1997) 3.35

Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol (1995) 3.30

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung. Microbiology (1999) 3.03

Endotoxin and immune activation in chronic heart failure: a prospective cohort study. Lancet (1999) 3.01

A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan. J Immunol (1998) 2.94

Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry. Cytometry (1999) 2.87

Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan. Am J Trop Med Hyg (1996) 2.72

Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth. Microbes Infect (2001) 2.50

Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. Lancet (1998) 2.39

A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics (1994) 2.31

Cholangiocarcinoma in patients with primary sclerosing cholangitis: a multicenter case-control study. Hepatology (2000) 2.21

Maintaining the immunological balance in parasitic infections: a role for TGF-beta? Parasitol Today (2000) 2.19

Plasma cytokine parameters and mortality in patients with chronic heart failure. Circulation (2000) 2.18

Predicting pressure ulcer risk: a multisite study of the predictive validity of the Braden Scale. Nurs Res (1998) 2.17

Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria. Infect Immun (1999) 2.16

Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia. J Infect Dis (2001) 2.15

Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm. Antimicrob Agents Chemother (1991) 2.09

Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol (1986) 2.06

Antileishmanial chalcones: statistical design, synthesis, and three-dimensional quantitative structure-activity relationship analysis. J Med Chem (1998) 2.06

The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response. Clin Exp Immunol (1992) 1.98

Predictors of large esophageal varices in patients with cirrhosis. Am J Gastroenterol (1999) 1.93

Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis. Br J Radiol (2003) 1.92

Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections. Immunol Lett (2000) 1.89

Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms. Infect Immun (1990) 1.81

The antileishmanial activity of novel oxygenated chalcones and their mechanism of action. J Antimicrob Chemother (1999) 1.77

Naturally acquired antibodies to the glutamate-rich protein are associated with protection against Plasmodium falciparum malaria. J Infect Dis (2000) 1.76

Inflammatory cytokines and the possible immunological role for lipoproteins in chronic heart failure. Int J Cardiol (2001) 1.71

Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children. Infect Immun (2001) 1.69

Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria. Immunology (1993) 1.64

Anthropogenic impacts on the distribution and biodiversity of benthic macroinvertebrates and water quality of the Langat River, Peninsular Malaysia. Ecotoxicol Environ Saf (2005) 1.61

Immunological features of kala-azar. Am J Trop Med Hyg (1978) 1.61

Nine-year longitudinal study of antibodies to variant antigens on the surface of Plasmodium falciparum-infected erythrocytes. Infect Immun (1999) 1.59

Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity. Immunology (1994) 1.55

The epidemiology of febrile malaria episodes in an area of unstable and seasonal transmission. Trans R Soc Trop Med Hyg (2001) 1.53

Pseudomonas aeruginosa alginate in cystic fibrosis sputum and the inflammatory response. Infect Immun (1990) 1.51

Intraoperative release of troponin T in coronary venous and arterial blood and its relation to recovery of left ventricular function and oxidative metabolism following coronary artery surgery. Heart (1998) 1.51

Increases in serum concentrations of cardiac proteins and the prediction of early postoperative cardiovascular complications in noncardiac surgery patients. Anaesthesia (2000) 1.51

The alteration of serum potassium level during sample transit. Practitioner (1989) 1.51

Leishmania donovani-reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis. Infect Immun (1993) 1.50

Anaemia caused by asymptomatic Plasmodium falciparum infection in semi-immune African schoolchildren. Trans R Soc Trop Med Hyg (2000) 1.49

Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village. Parasitology (1998) 1.48

Diagnosis of cystic fibrosis related diabetes: a selective approach in performing the oral glucose tolerance test based on a combination of clinical and biochemical criteria. Thorax (1999) 1.46

Evaluation of the efficacy of Iran leishmanin and comparison with leishmanins from Wellcome (UK) and Roma (Italy) in cured cutaneous leishmaniasis patients. Trans R Soc Trop Med Hyg (1994) 1.45

Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria. Infect Immun (1997) 1.45

Transient depletion of T cells with high LFA-1 expression from peripheral circulation during acute Plasmodium falciparum malaria. Eur J Immunol (1991) 1.44

Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum. Infect Immun (2001) 1.44

Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg (1994) 1.42

Random amplified polymorphic DNA for the differentiation of Leishmania donovani isolates from Sudan. Trans R Soc Trop Med Hyg (1996) 1.41

Prolongation of prothrombin time with ivermectin. Lancet (1988) 1.41

Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria. Br J Haematol (1997) 1.41

Peginterferon {alpha}-2b and ribavirin therapy in chronic hepatitis C genotype 4: impact of treatment duration and viral kinetics on sustained virological response. Gut (2005) 1.40

High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis. Clin Exp Immunol (1998) 1.40

A drawing for the Fabrica; and some thoughts upon the Vesalius muscle-men. Med Hist (1970) 1.39

Comparison of the immune profile of nonhealing cutaneous Leishmaniasis patients with those with active lesions and those who have recovered from infection. Infect Immun (2000) 1.39

[Effort phlebitis of the upper limb. Report of 5 cases]. J Mal Vasc (2001) 1.39

Effects of short-term supplementation with coenzyme Q10 on myocardial protection during cardiac operations. Ann Thorac Surg (1996) 1.39

Recommendations regarding total daily fluoride intake for Canadians. J Can Dent Assoc (1994) 1.39

Placement and replacement of restorations in a military population. J Can Dent Assoc (1991) 1.38

Pseudomonas aeruginosa exoproteases inhibit human neutrophil chemiluminescence. Infect Immun (1984) 1.37

Diallelic polymorphism may explain variations of the blood concentration of mannan-binding protein in Eskimos, but not in black Africans. Eur J Immunogenet (1992) 1.35

Effect of cyclosporin A on human neutrophil and monocyte function. Scand J Immunol (1985) 1.35

Interaction of Pseudomonas aeruginosa alkaline protease and elastase with human polymorphonuclear leukocytes in vitro. Infect Immun (1984) 1.34

The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type. APMIS (2000) 1.33

A new portable device for automatic controlled-gradient cryopreservation of blood mononuclear cells. J Immunol Methods (1993) 1.29

1,25-Dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level. Cytokine (1992) 1.29

Socio-economic and dietary influences on leg length and trunk length in childhood: a reanalysis of the Carnegie (Boyd Orr) survey of diet and health in prewar Britain (1937-39). Paediatr Perinat Epidemiol (1998) 1.27

Vertebral deformities and low bone mineral density in adults with cystic fibrosis: a cross-sectional study. Osteoporos Int (2001) 1.27

Ischaemic preconditioning reduces troponin T release in patients undergoing coronary artery bypass surgery. Heart (1997) 1.25

Increased plasma levels of soluble ICAM-1 and ELAM-1 (E-selectin) during acute Plasmodium falciparum malaria. Immunol Lett (1993) 1.25

Chronic Plasmodium falciparum infections in an area of low intensity malaria transmission in the Sudan. Parasitology (2000) 1.25

Endocytosis and vesicle trafficking during tip growth of root hairs. Protoplasma (2005) 1.24

Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida. Planta Med (1999) 1.24

What is the cause of lymphopenia in malaria? Infect Immun (2000) 1.23