Published in Jpn J Pharmacol on April 01, 1999
Depression and osteoporosis: epidemiology and potential mediating pathways. Osteoporos Int (2007) 1.18
Pentoxifylline attenuates nociceptive sensitization and cytokine expression in a tibia fracture rat model of complex regional pain syndrome. Eur J Pain (2008) 1.13
Association between a variation in the phosphodiesterase 4D gene and bone mineral density. BMC Med Genet (2005) 1.05
EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis. BMC Pharmacol (2004) 0.80
Cyclic nucleotides and phosphodiesterases in monocytic differentiation. Handb Exp Pharmacol (2011) 0.79
KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways. PLoS One (2013) 0.77
Rolipram, a phosphodiesterase 4 inhibitor, stimulates inducible cAMP early repressor expression in osteoblasts. Yonsei Med J (2005) 0.76
Phosphodiesterase 4 inhibitor rolipram potentiates the inhibitory effect of calcitonin on osteoclastogenesis. J Bone Miner Metab (2006) 0.76
A novel T-cell line derived from adult T-cell leukemia. Gan (1980) 3.21
VEGF-initiated blood-retinal barrier breakdown in early diabetes. Invest Ophthalmol Vis Sci (2001) 3.08
Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49
A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res (1997) 2.46
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta (2001) 2.41
Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. J Biol Chem (1999) 2.12
Clinical studies of de novo aneurysms. Neurosurgery (1993) 2.10
Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetes. Invest Ophthalmol Vis Sci (2000) 2.05
Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA). Br J Cancer (2007) 2.00
2/8 translocation in a Japanese Burkitt's lymphoma. Experientia (1979) 1.91
VEGF increases retinal vascular ICAM-1 expression in vivo. Invest Ophthalmol Vis Sci (1999) 1.89
Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc Natl Acad Sci U S A (1992) 1.76
Involvement of tumor necrosis factor-alpha in the pathogenesis of activated macrophage-mediated hepatitis in mice. Gastroenterology (1990) 1.70
Cloning, sequence, and expression of a chitinase gene from a marine bacterium, Altermonas sp. strain O-7. J Bacteriol (1993) 1.67
Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage (2006) 1.64
Lyme disease spirochetes in Japan: enzootic transmission cycles in birds, rodents, and Ixodes persulcatus ticks. J Infect Dis (1994) 1.60
Endothelial cells actively synthesize and secrete adrenomedullin. Biochem Biophys Res Commun (1994) 1.60
Prolonged paraplegia after iohexol myelography. Lancet (1991) 1.58
Mixed infection of different Borrelia species among Apodemus speciosus mice in Hokkaido, Japan. J Clin Microbiol (1995) 1.58
Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS. Biochemistry (1991) 1.57
Photosensitivity of a protoporphyrin-accumulating, light-sensitive mutant (visA) of Escherichia coli K-12. Proc Natl Acad Sci U S A (1991) 1.54
Usefulness of enzyme-linked immunosorbent assay using recombinant desmogleins 1 and 3 for serodiagnosis of pemphigus. Br J Dermatol (1999) 1.52
Adrenocorticotropin-independent macronodular adrenocortical hyperplasia associated with multiple colon adenomas/carcinomas which showed a point mutation in the APC gene. Intern Med (1997) 1.50
Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology (Oxford) (2008) 1.48
Organic-solvent-tolerant bacterium which secretes organic-solvent-stable lipolytic enzyme. Appl Environ Microbiol (1994) 1.47
Incidence and properties of renal masses and asymptomatic renal cell carcinoma detected by abdominal ultrasonography. J Urol (1990) 1.47
Haemophagocytic syndrome in a patient with dermatomyositis. Br J Rheumatol (1998) 1.43
Association between up-regulation of stress-responsive genes and hypomethylation of genomic DNA in tobacco plants. Mol Genet Genomics (2004) 1.38
[Does lung age help smokers quit?]. Nihon Kokyuki Gakkai Zasshi (2011) 1.38
Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species. Proc Natl Acad Sci U S A (1984) 1.38
Purification, properties, and partial amino acid sequences of thermostable xylanases from Streptomyces thermoviolaceus OPC-520. Appl Environ Microbiol (1992) 1.38
Effect of anti-macrophage migration inhibitory factor antibody on lipopolysaccharide-induced pulmonary neutrophil accumulation. Am J Respir Crit Care Med (1998) 1.35
Isolation of porcine follicular fluid inhibin of 32K daltons. Biochem Biophys Res Commun (1985) 1.34
The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine. J Bone Miner Res (1999) 1.31
Enhanced expression of the protein kinase substrate annexin in human hepatocellular carcinoma. Hepatology (1996) 1.30
Cloning, expression and characterization of the human transcription elongation factor, TFIIS. Nucleic Acids Res (1991) 1.30
Long-term results of anterior interbody fusion for treatment of degenerative spondylolisthesis. Spine (Phila Pa 1976) (1990) 1.28
Visualization and quantitative analysis of leukocyte dynamics in retinal microcirculation of rats. Invest Ophthalmol Vis Sci (1996) 1.27
Diabetic myopia--is it lens-induced? An oculometric study comprising ultrasound measurements. Acta Ophthalmol (Copenh) (1987) 1.27
Comparative studies between pathogenesis of street and fixed rabies infection. J Exp Med (1967) 1.27
Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema. Thorax (2002) 1.26
Nicotinamide inhibits sodium-dependent phosphate cotransport activity in rat small intestine. Nephrol Dial Transplant (1999) 1.22
Relation of oxygen delivery, mixed venous oxygenation, and pulmonary hemodynamics to prognosis in chronic obstructive pulmonary disease. N Engl J Med (1983) 1.21
Comparison of the epidemiology of acne vulgaris among Caucasian, Asian, Continental Indian and African American women. J Eur Acad Dermatol Venereol (2010) 1.20
Characterization of Borrelia burgdorferi isolated from Ixodes persulcatus and Ixodes ovatus ticks in Japan. Am J Trop Med Hyg (1992) 1.18
Hexagonally deformed Fermi surface of the 3D topological insulator Bi2Se3. Phys Rev Lett (2010) 1.18
Biological studies on bleomycin A. J Antibiot (Tokyo) (1967) 1.18
Differentiation by immunoferritin of herpes simplex antigens with the use of rabbit 7S and 19S antibodies from early (7-day) and late (7-week) immune sera. J Natl Cancer Inst (1971) 1.17
In situ hybridisation study of type I, II, X collagens and aggrecan mRNas in the developing condylar cartilage of fetal mouse mandible. J Anat (1999) 1.17
Mammalian nuclear transplantation to Germinal Vesicle stage Xenopus oocytes - a method for quantitative transcriptional reprogramming. Methods (2010) 1.17
Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice. Hepatology (1990) 1.17
Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3. Biochem J (1999) 1.16
Cysteine proteinases and cystatin C in bronchoalveolar lavage fluid from subjects with subclinical emphysema. Eur Respir J (1998) 1.15
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol (2002) 1.14
Isolation and characterization of chicken hypothalamic luteinizing hormone-releasing hormone. Biochem Biophys Res Commun (1982) 1.14
Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone. J Bacteriol (1992) 1.13
Intramedullary teratoma of the spine: report of two adult cases. Spinal Cord (2002) 1.13
Cloning and sequence analysis of genes encoding xylanases and acetyl xylan esterase from Streptomyces thermoviolaceus OPC-520. Appl Environ Microbiol (1997) 1.13
Sp family members and nuclear factor-Y cooperatively stimulate transcription from the rat pyruvate kinase M gene distal promoter region via their direct interactions. J Biol Chem (2000) 1.12
Selective delivery of estradiol to bone by aspartic acid oligopeptide and its effects on ovariectomized mice. Endocrinology (2001) 1.12
[Transition of occurrence of anisakiasis and its paratenic host fishes in Japan, with pathogenesis of anisakiasis]. Hokkaido Igaku Zasshi (1988) 1.12
Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. Am J Respir Crit Care Med (1999) 1.12
Electron microscopic studies of tumor viruses. I. Entry of murine leukemia virus into mouse embryo fibroblasts. J Virol (1971) 1.12
Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms. Neurology (2002) 1.11
Characterization of chitinase C from a marine bacterium, Alteromonas sp. strain O-7, and its corresponding gene and domain structure. Appl Environ Microbiol (1998) 1.10
Experimental evaluation of atrial function in right atrium--pulmonary artery conduit operation for tricuspid atresia. J Thorac Cardiovasc Surg (1981) 1.10
Selective drug delivery system to bone: small peptide (Asp)6 conjugation. J Bone Miner Res (2000) 1.10
Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines. Cancer Lett (2000) 1.10
Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci (2000) 1.10
Antigenic and genetic characterization of Borrelia species isolated from Ixodes persulcatus in Hokkaido, Japan. J Clin Microbiol (1993) 1.09
Experimental realization of a three-dimensional topological insulator phase in ternary chalcogenide TlBiSe₂. Phys Rev Lett (2010) 1.09
Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein. J Biol Chem (1999) 1.08
Use of local cerebral blood flow monitoring to predict brain damage after disturbance to the venous circulation: cortical vein occlusion model by photochemical dye. Neurosurgery (1995) 1.08
Chromosome translocations in Burkitt's lymphoma. N Engl J Med (1981) 1.08
Serologic classification of Herpes simplex viruses. J Immunol (1971) 1.08
Regulation of osteopontin expression in osteoblasts. Ann N Y Acad Sci (1995) 1.08
Vascular smooth muscle cell growth-promoting factor/F-spondin inhibits angiogenesis via the blockade of integrin alphavbeta3 on vascular endothelial cells. J Cell Physiol (2001) 1.07
Beneficial effect of the active form of vitamin D3 against LPS-induced DIC but not against tissue-factor-induced DIC in rat models. Thromb Haemost (2001) 1.07
Formation of vinblastine in multiple shoot culture of Catharanthus roseus. Planta Med (1988) 1.06
Ethanol-induced hepatic fibrosis in the rat: role of the amount of dietary fat. Alcohol Clin Exp Res (1986) 1.06
Molecular cloning of a second human stanniocalcin homologue (STC2). Biochem Biophys Res Commun (1998) 1.05
Characterization of spirochetes isolated from ticks (Ixodes tanuki, Ixodes turdus, and Ixodes columnae) and comparison of the sequences with those of Borrelia burgdorferi sensu lato strains. Appl Environ Microbiol (1996) 1.05
Perfluoroether liquid as a long-term vitreous substitute. An experimental study. Retina (1985) 1.05
A study on postoperative enteritis caused by methicillin-resistant Staphylococcus aureus. Surg Today (1993) 1.05
Subjective complaints in orthopedists and general surgeons. Int Arch Occup Environ Health (1995) 1.04
Surface scattering via bulk continuum states in the 3D topological insulator Bi2Se3. Phys Rev Lett (2011) 1.04
Purification and characterization of two types of alkaline serine proteases produced by an alkalophilic actinomycete. J Appl Bacteriol (1990) 1.04
Cloning, gene structure and dietary regulation of the type-IIc Na/Pi cotransporter in the mouse kidney. Pflugers Arch (2003) 1.04
Radioimmunoassay of inhibin in various mammals. J Endocrinol (1989) 1.04
Gene sequence, purification and characterization of N-acetyl-beta-glucosaminidase from a marine bacterium, Alteromonas sp. strain O-7. Gene (1994) 1.03
Serum response factor has functional roles both in indirect binding to the CArG box and in the transcriptional activation function of human T-cell leukemia virus type I Tax. J Virol (1994) 1.03
Complement activation in patients with primary antiphospholipid syndrome. Ann Rheum Dis (2008) 1.03
Experimental verification of PbBi2Te4 as a 3D topological insulator. Phys Rev Lett (2012) 1.03
Extracellular role of S100A4 calcium-binding protein in the periodontal ligament. Biochem Biophys Res Commun (1999) 1.03
Multiple coronary artery aneurysms resulting in myocardial infarction in a young man: treatment by double aorta-coronary saphenous vein bypass grafting. J Thorac Cardiovasc Surg (1975) 1.03
Cloning and sequence analysis of the gene encoding a thermostable chitinase from Streptomyces thermoviolaceus OPC-520. Gene (1993) 1.03
Effect of aminophylline on brain tissue oxygenation in patients with chronic obstructive lung disease. Thorax (1992) 1.03