Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
|
Science
|
1997
|
11.53
|
2
|
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
|
J Neurosci
|
2000
|
3.16
|
3
|
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits.
|
Proc Natl Acad Sci U S A
|
2007
|
3.07
|
4
|
Early and progressive accumulation of reactive microglia in the Huntington disease brain.
|
J Neuropathol Exp Neurol
|
2001
|
2.17
|
5
|
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy.
|
Ann Intern Med
|
1984
|
2.01
|
6
|
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.
|
Proc Natl Acad Sci U S A
|
2001
|
1.99
|
7
|
Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways.
|
Exp Neurol
|
1998
|
1.85
|
8
|
Huntingtin localization in brains of normal and Huntington's disease patients.
|
Ann Neurol
|
1997
|
1.82
|
9
|
Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease.
|
J Neurosci
|
2001
|
1.52
|
10
|
Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.
|
Proc Natl Acad Sci U S A
|
1990
|
1.41
|
11
|
Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.
|
J Neurosci
|
1999
|
1.40
|
12
|
Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus.
|
Proc Natl Acad Sci U S A
|
1992
|
1.27
|
13
|
Expression of normal and mutant huntingtin in the developing brain.
|
J Neurosci
|
1996
|
1.21
|
14
|
Fast transport and retrograde movement of huntingtin and HAP 1 in axons.
|
Neuroreport
|
1997
|
1.20
|
15
|
Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?
|
Lancet
|
1998
|
1.17
|
16
|
Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation.
|
J Biol Chem
|
2000
|
1.15
|
17
|
Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease.
|
J Neuropathol Exp Neurol
|
1999
|
1.10
|
18
|
Analysis of Huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons.
|
J Comp Neurol
|
1999
|
1.07
|
19
|
Differential regulation of fos family genes in the ventrolateral and dorsomedial subdivisions of the rat suprachiasmatic nucleus.
|
Neuroscience
|
2000
|
1.05
|
20
|
Localization of immunoreactive enkephalins in GABA synthesizing neurons of the rat neostriatum.
|
Brain Res
|
1984
|
1.03
|
21
|
Light and electron microscopic localization of immunoreactive Leu-enkephalin in the monkey basal ganglia.
|
J Neurosci
|
1982
|
0.99
|
22
|
Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons.
|
Brain Res
|
1993
|
0.96
|
23
|
Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin.
|
Neuroscience
|
1999
|
0.90
|
24
|
Ultrastructural features of immunoreactive somatostatin neurons in the rat caudate nucleus.
|
J Neurosci
|
1982
|
0.89
|
25
|
A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13.
|
J Clin Endocrinol Metab
|
1997
|
0.89
|
26
|
Functional role for Sp1 in the transcriptional amplification of a cell cycle regulated histone H4 gene.
|
Biochemistry
|
1995
|
0.87
|
27
|
Sustained remission of Nelson's syndrome after stopping cyproheptadine treatment.
|
N Engl J Med
|
1980
|
0.87
|
28
|
Ultrastructural localization of immunoreactive calbindin-D28k in the rat and monkey basal ganglia, including subcellular distribution with colloidal gold labeling.
|
J Comp Neurol
|
1989
|
0.86
|
29
|
Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.
|
Exp Neurol
|
2002
|
0.86
|
30
|
Substance P and neurotensin: their roles in the regulation of anterior pituitary function.
|
Annu Rev Physiol
|
1986
|
0.84
|
31
|
The distribution of substance P-containing neurons in the cat Edinger-Westphal nucleus: relationship to efferent projection systems.
|
Brain Res
|
1983
|
0.84
|
32
|
Does capsaicin relieve the pain of diabetic neuropathy?
|
Pain
|
1990
|
0.84
|
33
|
Fluorescent and biotin probes for dopamine receptors: D1 and D2 receptor affinity and selectivity.
|
Mol Pharmacol
|
1990
|
0.83
|
34
|
Temporal regulation of light-induced Fos and Fos-like protein expression in the ventrolateral subdivision of the rat suprachiasmatic nucleus.
|
Neuroscience
|
1994
|
0.82
|
35
|
Substance P and neurotensin.
|
Recent Prog Horm Res
|
1982
|
0.81
|
36
|
Compositional changes of AP-1 DNA-binding proteins are regulated by light in a mammalian circadian clock.
|
Neuron
|
1993
|
0.80
|
37
|
Monoamines in the brain cerebrospinal fluid of facial pain patients.
|
Anesth Prog
|
1992
|
0.80
|
38
|
Downregulation of histone H4 gene transcription during postnatal development in transgenic mice and at the onset of differentiation in transgenically derived calvarial osteoblast cultures.
|
J Cell Biochem
|
1992
|
0.80
|
39
|
Ultrastructural localization and biochemical features of immunoreactive LEU-enkephalin in monkey dorsal horn.
|
J Neurosci
|
1981
|
0.79
|
40
|
Prognostic differences in subgroups of patients with electrographic evidence of subendocardial or transmural myocardial infarction. The favorable outlook for patients with an initially normal QRS complex.
|
Am J Med
|
1980
|
0.79
|
41
|
The stability and metabolism of intravenously administered neurotensin in the rat.
|
Peptides
|
1982
|
0.78
|
42
|
Frequency of painless myocardial ischemia during exercise tolerance testing in patients with and without diabetes mellitus.
|
Am J Cardiol
|
1987
|
0.78
|
43
|
Comparative metabolic clearance rates of beta-endorphin and beta-lipotropin in humans.
|
Life Sci
|
1981
|
0.78
|
44
|
The differential effects of thyroid and gonadal hormones on substance P content in the anterior pituitary of the prepubertal rat.
|
Endocrinology
|
1985
|
0.78
|
45
|
c-Fos expression in the rat intergeniculate leaflet: photic regulation, co-localization with Fos-B, and cellular identification.
|
Brain Res
|
1996
|
0.78
|
46
|
Plasma immunoreactive beta-endorphin is elevated in uraemia.
|
Clin Endocrinol (Oxf)
|
1983
|
0.77
|
47
|
Immunohistochemical evidence for neural mediation of VIP activity in the dogfish rectal gland.
|
Peptides
|
1988
|
0.77
|
48
|
Regulation by thyroid hormone of the concentration of substance P in the rat anterior pituitary.
|
Endocrinology
|
1984
|
0.77
|
49
|
Unexpected c-fos gene expression in the suprachiasmatic nucleus of mice entrained to a skeleton photoperiod.
|
J Biol Rhythms
|
1996
|
0.77
|
50
|
Somatostatin is increased in the basal ganglia in Huntington disease.
|
Ann Neurol
|
1983
|
0.77
|
51
|
In vitro stimulation of c-Fos protein expression in the suprachiasmatic nucleus of hypothalamic slices.
|
Brain Res Mol Brain Res
|
1996
|
0.77
|
52
|
Diabetes mellitus and silent myocardial ischemia.
|
Adv Cardiol
|
1990
|
0.76
|
53
|
A Golgi study of the monkey paraventricular nucleus: neuronal types, afferent and efferent fibers.
|
J Comp Neurol
|
1987
|
0.76
|
54
|
Synaptic interactions between GABAergic neurons and trigeminothalamic cells in the rat trigeminal nucleus caudalis.
|
Synapse
|
1990
|
0.76
|
55
|
Immunoreactive leu-enkephalin in the monkey hypothalamus including observations on its ultrastructural localization in the paraventricular nucleus.
|
J Comp Neurol
|
1984
|
0.76
|
56
|
Dde-I restriction endonuclease fragmentation: a novel method of generating cDNA probes for in situ hybridization in brain.
|
J Histochem Cytochem
|
1997
|
0.76
|
57
|
The effects of gonadal steroids on the content of substance P in the rat anterior pituitary.
|
Endocrinology
|
1984
|
0.76
|
58
|
The myopathy of Cushing's syndrome.
|
Muscle Nerve
|
1993
|
0.75
|
59
|
Ultrastructural localization of immunoreactive neurotensin in the monkey superficial dorsal horn.
|
J Comp Neurol
|
1984
|
0.75
|
60
|
Impaired clearance of beta-lipotropin in uremia.
|
J Clin Endocrinol Metab
|
1981
|
0.75
|
61
|
Metastatic papillary thyroid carcinoma to lung diagnosed by bronchoalveolar lavage.
|
J Clin Endocrinol Metab
|
1996
|
0.75
|
62
|
Circadian regulation of Fos B is different from c-Fos in the rat suprachiasmatic nucleus.
|
Brain Res Mol Brain Res
|
1994
|
0.75
|
63
|
Light microscopic and ultrastructural localization of immunoreactive substance P in the dorsal horn of monkey spinal cord.
|
Neuroscience
|
1982
|
0.75
|
64
|
Immunoreactive substance P in the substantia nigra of the monkey: light and electron microscopic localization.
|
Brain Res
|
1982
|
0.75
|
65
|
Glutamic acid decarboxylase and enkephalin immunoreactive axon terminals in the rat neostriatum synapse with striatonigral neurons.
|
Brain Res
|
1986
|
0.75
|
66
|
Quantitative electron microscopic study of immunoreactive somatostatin axons in the rat neostriatum.
|
Neurosci Lett
|
1984
|
0.75
|
67
|
Transient myocardial perfusion abnormalities in diabetic patients: a prospective study using thallium exercise tolerance testing.
|
Cardiology
|
1991
|
0.75
|
68
|
Failure of bromocriptine to lower plasma catecholamines in normal men and women.
|
J Clin Endocrinol Metab
|
1982
|
0.75
|