PubRank

R B Sartor

Author PubWeight™ 110.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998 7.86
2 Experimental models of inflammatory bowel disease. Gastroenterology 1995 6.28
3 Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J Clin Invest 1996 4.59
4 Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification. Gastroenterology 1992 3.04
5 Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J Biol Chem 1999 2.79
6 Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol 1999 2.55
7 Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2. J Clin Invest 2000 2.27
8 The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection. Am J Physiol Cell Physiol 2000 2.21
9 Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor. Hepatology 1998 2.18
10 Mechanisms of acute and chronic intestinal inflammation induced by indomethacin. Inflammation 1993 2.03
11 Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment. Gut 2003 2.02
12 Different subsets of enteric bacteria induce and perpetuate experimental colitis in rats and mice. Infect Immun 2001 1.94
13 Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect Immun 1999 1.85
14 IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation. Am J Physiol 1999 1.83
15 Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells. J Immunol 1997 1.80
16 Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone. Gastroenterology 2001 1.77
17 Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline. Gastroenterology 1991 1.72
18 Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth. Gastroenterology 1990 1.59
19 Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments. Gastroenterology 1985 1.57
20 Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats. Gastroenterology 1993 1.54
21 Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. J Immunol 1998 1.51
22 Interplay of commensal and pathogenic bacteria, genetic mutations, and immunoregulatory defects in the pathogenesis of inflammatory bowel diseases. J Intern Med 2008 1.48
23 Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats. Gastroenterology 1999 1.47
24 Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats. Gastroenterology 1994 1.45
25 Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in Tg(epsilon26) mice. Gastroenterology 2001 1.43
26 Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10-deficient mice. Infect Immun 2000 1.33
27 Interleukin 10 suppresses experimental chronic, granulomatous inflammation induced by bacterial cell wall polymers. Gut 1996 1.31
28 Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells. Am J Physiol 1998 1.29
29 Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors. Gut 1998 1.25
30 IGF-I and procollagen alpha1(I) are coexpressed in a subset of mesenchymal cells in active Crohn's disease. Am J Physiol Gastrointest Liver Physiol 2000 1.24
31 Bacterial cell wall polymers promote intestinal fibrosis by direct stimulation of myofibroblasts. Am J Physiol 1999 1.22
32 Lipopolysaccharide induces recurrence of arthritis in rat joints previously injured by peptidoglycan-polysaccharide. J Exp Med 1987 1.21
33 Murine model of Clostridium difficile infection with aged gnotobiotic C57BL/6 mice and a BI/NAP1 strain. J Infect Dis 2010 1.19
34 Antibiotics with a selective aerobic or anaerobic spectrum have different therapeutic activities in various regions of the colon in interleukin 10 gene deficient mice. Gut 2003 1.17
35 Subtherapeutic corticosteroids potentiate the ability of interleukin 10 to prevent chronic inflammation in rats. Gastroenterology 1998 1.14
36 Probiotics and inflammatory bowel diseases. Am J Gastroenterol 2000 1.10
37 Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. J Clin Invest 1992 1.07
38 Postoperative recurrence of Crohn's disease: the enemy is within the fecal stream. Gastroenterology 1998 1.06
39 Biliary tract disease in rats with experimental small bowel bacterial overgrowth. Hepatology 1991 1.04
40 Evidence for peptidoglycan absorption in rats with experimental small bowel bacterial overgrowth. Infect Immun 1991 1.04
41 Reactivation of arthritis induced by small bowel bacterial overgrowth in rats: role of cytokines, bacteria, and bacterial polymers. Infect Immun 1995 1.04
42 Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells. Immunology 2004 0.98
43 TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells. J Immunol 1999 0.97
44 Insulinlike growth factor I and interleukin 1 beta messenger RNA in a rat model of granulomatous enterocolitis and hepatitis. Gastroenterology 1993 0.97
45 Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats. Clin Exp Immunol 2004 0.96
46 Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection. Am J Physiol Gastrointest Liver Physiol 2008 0.96
47 Keratinocyte growth factor-2 (FGF-10) promotes healing of experimental small intestinal ulceration in rats. Am J Physiol Gastrointest Liver Physiol 2000 0.96
48 NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases. Inflamm Bowel Dis 2000 0.95
49 Role of kallikrein-kinin system in pathogenesis of bacterial cell wall-induced inflammation. Am J Physiol 1991 0.94
50 Local production of corticotropin releasing hormone is increased in experimental intestinal inflammation in rats. Gut 1996 0.94
51 The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLA-B27 transgenic rats. J Exp Med 1998 0.92
52 Cellular differentiation causes a selective down-regulation of interleukin (IL)-1beta-mediated NF-kappaB activation and IL-8 gene expression in intestinal epithelial cells. J Biol Chem 2000 0.90
53 Identification and characterization of rat intestinal lamina propria cells: consequences of microbial colonization. Vet Immunol Immunopathol 1992 0.89
54 Inhibition of plasma kallikrein prevents peptidoglycan-induced arthritis in the Lewis rat. FASEB J 1995 0.88
55 Disrupted B-lymphocyte development and survival in interleukin-2-deficient mice. Immunology 2001 0.87
56 Importance of intestinal mucosal immunity and luminal bacterial cell wall polymers in the aetiology of inflammatory joint diseases. Baillieres Clin Rheumatol 1989 0.87
57 Kininogens are antithrombotic proteins In vivo. Arterioscler Thromb Vasc Biol 1999 0.85
58 Development of a scoring system to predict mortality from upper gastrointestinal bleeding. Am J Med Sci 1987 0.84
59 Bacterial cell wall polymers (peptidoglycan-polysaccharide) cause reactivation of arthritis. Infect Immun 1993 0.84
60 Expression and localization of IL-1beta mRNA is interrelated with cytoskeletal rearrangement in monocytes stimulated by adherence: a light microscopy in situ hybridization study. Immunol Cell Biol 2001 0.83
61 Differential expression of interleukin 1 receptor antagonist isoforms in human intestinal epithelial cells. Gastroenterology 1998 0.83
62 Specific inhibition of plasma kallikrein modulates chronic granulomatous intestinal and systemic inflammation in genetically susceptible rats. FASEB J 1998 0.83
63 New therapeutic approaches to Crohn's disease. N Engl J Med 2000 0.83
64 Endoscopic appearance of cancer metastatic to the stomach. J Clin Gastroenterol 1981 0.82
65 Examining the role of inflammatory cytokines in chronic inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1993 0.82
66 Localized gut-associated lymphoid tissue hemorrhage induced by intravenous peptidoglycan-polysaccharide polymers. Infect Immun 1986 0.82
67 Kallikrein-kininogen system activation and bradykinin (B2) receptors in indomethacin induced enterocolitis in genetically susceptible Lewis rats. Gut 1998 0.81
68 Expression of intrinsic factor in rat and murine gastric mucosal cell lineages is modified by inflammation. Am J Pathol 2000 0.81
69 The plasma kallikrein-kinin system in sepsis, inflammatory arthritis, and enterocolitis. Clin Rev Allergy Immunol 1998 0.81
70 Selective plasma kallikrein inhibitor attenuates acute intestinal inflammation in Lewis rat. Dig Dis Sci 1996 0.80
71 Multimodal optical and Gd-based nanoparticles for imaging in inflammatory arthritis. Clin Exp Rheumatol 2009 0.80
72 A rat model of ileal pouch-rectal anastomosis. Inflamm Bowel Dis 1998 0.80
73 Bradykinin receptor antagonists type 2 attenuate the inflammatory changes in peptidoglycan-induced acute arthritis in the Lewis rat. Inflamm Res 2001 0.79
74 Adoptive transfer of nontransgenic mesenteric lymph node cells induces colitis in athymic HLA-B27 transgenic nude rats. Clin Exp Immunol 2006 0.79
75 Hepatobiliary injury associated with experimental small-bowel bacterial overgrowth in rats. Immunol Res 1991 0.79
76 Activation of the kallikrein-kinin system in arthritis and enterocolitis in genetically susceptible rats: modulation by a selective plasma kallikrein inhibitor. Proc Assoc Am Physicians 1997 0.78
77 Probiotics in chronic pouchitis: restoring luminal microbial balance. Gastroenterology 2000 0.77
78 Regulatory CD4+CD25+ cells reverse imbalances in the T cell pool of bone marrow transplanted TGepsilon26 mice leading to the prevention of colitis. Gut 2005 0.77
79 Low endogenous prostaglandin E2 predisposes to relapsing inflammation in experimental rat enterocolitis. Dig Dis Sci 1999 0.77
80 Localization and secretion of tissue kallikrein in peptidoglycan-induced enterocolitis in Lewis rats. Am J Physiol 1998 0.76
81 Cyclosporine therapy for inflammatory bowel disease. N Engl J Med 1994 0.75
82 Duct proliferation following biliary obstruction in the rat. Gastroenterology 1991 0.75
83 Eicosanoid regulation of acute intestinal vascular permeability induced by intravenous peptidoglycan-polysaccharide polymers. Agents Actions 1989 0.75
84 Role of kallikrein-kinin system in the pathogenesis of bacterial cell wall-induced inflammation and enterocolitis. Trans Assoc Am Physicians 1992 0.75
85 Low endogenous prostaglandin E2 predisposes to relapsing inflammation in experimental rat enterocolitis. Dig Dis Sci 2000 0.75
86 The contact system in experimental enterocolitis. Immunopharmacology 1996 0.75