|
1
|
Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization.
|
Am J Pathol
|
1997
|
2.73
|
|
2
|
Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization.
|
Am J Pathol
|
2000
|
2.41
|
|
3
|
VEGF is major stimulator in model of choroidal neovascularization.
|
Invest Ophthalmol Vis Sci
|
2000
|
2.38
|
|
4
|
Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model.
|
Am J Pathol
|
1998
|
2.33
|
|
5
|
Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression.
|
Invest Ophthalmol Vis Sci
|
1999
|
2.23
|
|
6
|
Subretinal fluid stimulation of retinal pigment epithelial cell migration and proliferation is dependent on certain features of the detachment or its treatment.
|
Arch Ophthalmol
|
1989
|
1.98
|
|
7
|
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization.
|
J Cell Physiol
|
2001
|
1.94
|
|
8
|
Upregulation of vascular endothelial growth factor in ischemic and non-ischemic human and experimental retinal disease.
|
Histol Histopathol
|
1997
|
1.90
|
|
9
|
Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.
|
Gene Ther
|
2006
|
1.86
|
|
10
|
An exploratory study of the safety, tolerability and bioactivity of a single intravitreal injection of vascular endothelial growth factor Trap-Eye in patients with diabetic macular oedema.
|
Br J Ophthalmol
|
2009
|
1.82
|
|
11
|
Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors.
|
Invest Ophthalmol Vis Sci
|
1998
|
1.68
|
|
12
|
Intravitreal sustained release of VEGF causes retinal neovascularization in rabbits and breakdown of the blood-retinal barrier in rabbits and primates.
|
Exp Eye Res
|
1997
|
1.58
|
|
13
|
Bevacizumab suppresses choroidal neovascularisation caused by pathological myopia.
|
Br J Ophthalmol
|
2005
|
1.49
|
|
14
|
Clinical risk factors for proliferative vitreoretinopathy.
|
Arch Ophthalmol
|
1989
|
1.49
|
|
15
|
Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors.
|
Invest Ophthalmol Vis Sci
|
2000
|
1.48
|
|
16
|
Oxidative damage in age-related macular degeneration.
|
Histol Histopathol
|
2007
|
1.44
|
|
17
|
Eye pain after vitreoretinal surgery: a prospective study of 185 patients.
|
Retina
|
2001
|
1.44
|
|
18
|
Immunohistochemical localization of blood-retinal barrier breakdown in human diabetics.
|
Am J Pathol
|
1989
|
1.38
|
|
19
|
Dramatic inhibition of retinal and choroidal neovascularization by oral administration of a kinase inhibitor.
|
Am J Pathol
|
1999
|
1.34
|
|
20
|
Cellular mechanisms of blood-retinal barrier dysfunction in macular edema.
|
Doc Ophthalmol
|
1999
|
1.31
|
|
21
|
Retinal pigment epithelial cells release an inhibitor of neovascularization.
|
Arch Ophthalmol
|
1985
|
1.30
|
|
22
|
Blood-retinal barrier (BRB) breakdown in experimental autoimmune uveoretinitis: comparison with vascular endothelial growth factor, tumor necrosis factor alpha, and interleukin-1beta-mediated breakdown.
|
J Neurosci Res
|
1997
|
1.29
|
|
23
|
Angiopoietin 2 expression in the retina: upregulation during physiologic and pathologic neovascularization.
|
J Cell Physiol
|
2000
|
1.28
|
|
24
|
The extracellular matrix of human retinal pigment epithelial cells in vivo and its synthesis in vitro.
|
Invest Ophthalmol Vis Sci
|
1986
|
1.28
|
|
25
|
Ultrastructural and electron-immunocytochemical characterization of cells in epiretinal membranes.
|
Invest Ophthalmol Vis Sci
|
1990
|
1.26
|
|
26
|
Cryotherapy causes extensive breakdown of the blood-retinal barrier. A comparison with argon laser photocoagulation.
|
Arch Ophthalmol
|
1985
|
1.21
|
|
27
|
Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization.
|
Am J Pathol
|
1998
|
1.20
|
|
28
|
Role of hypoxia and extracellular matrix-integrin binding in the modulation of angiogenic growth factors secretion by retinal pigmented epithelial cells.
|
J Cell Biochem
|
1999
|
1.19
|
|
29
|
Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin.
|
Am J Pathol
|
2001
|
1.18
|
|
30
|
Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin.
|
Arch Ophthalmol
|
1986
|
1.17
|
|
31
|
Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model.
|
Lab Invest
|
1996
|
1.16
|
|
32
|
Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier.
|
Gene Ther
|
2004
|
1.15
|
|
33
|
Hyperoxia causes decreased expression of vascular endothelial growth factor and endothelial cell apoptosis in adult retina.
|
J Cell Physiol
|
1999
|
1.14
|
|
34
|
Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/vascular permeability factor.
|
Am J Pathol
|
1995
|
1.13
|
|
35
|
Localization of TIMP-3 mRNA expression to the retinal pigment epithelium.
|
Invest Ophthalmol Vis Sci
|
1996
|
1.13
|
|
36
|
Nonviral ocular gene transfer.
|
Gene Ther
|
2005
|
1.13
|
|
37
|
Vitreous aspirates from patients with proliferative vitreoretinopathy stimulate retinal pigment epithelial cell migration.
|
Arch Ophthalmol
|
1985
|
1.13
|
|
38
|
Growth factor responsiveness of human retinal pigment epithelial cells.
|
Invest Ophthalmol Vis Sci
|
1990
|
1.12
|
|
39
|
Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice.
|
Am J Pathol
|
2001
|
1.11
|
|
40
|
Serum contains chemoattractants for human retinal pigment epithelial cells.
|
Arch Ophthalmol
|
1984
|
1.10
|
|
41
|
Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium.
|
Invest Ophthalmol Vis Sci
|
2000
|
1.09
|
|
42
|
Expression and permeation properties of the K(+) channel Kir7.1 in the retinal pigment epithelium.
|
J Physiol
|
2001
|
1.09
|
|
43
|
Retinal thinning and regression of neovascularization.
|
Arch Ophthalmol
|
1988
|
1.07
|
|
44
|
Improved visual results after surgical repair of cytomegalovirus-related retinal detachments.
|
Ophthalmology
|
1994
|
1.07
|
|
45
|
Photoreceptor-specific expression of platelet-derived growth factor-B results in traction retinal detachment.
|
Am J Pathol
|
2000
|
1.07
|
|
46
|
Platelet-derived growth factor is chemotactic for human retinal pigment epithelial cells.
|
Arch Ophthalmol
|
1985
|
1.06
|
|
47
|
Localisation of vascular endothelial growth factor and its receptors to cells of vascular and avascular epiretinal membranes.
|
Br J Ophthalmol
|
1997
|
1.04
|
|
48
|
Neurotrophic signaling in normal and degenerating rodent retinas.
|
Exp Eye Res
|
2001
|
1.04
|
|
49
|
Blood-retinal barrier breakdown in retinitis pigmentosa: light and electron microscopic immunolocalization.
|
Histol Histopathol
|
1995
|
1.03
|
|
50
|
Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.
|
Hum Mol Genet
|
1999
|
1.02
|
|
51
|
Gentamicin toxicity in the primate retina.
|
Arch Ophthalmol
|
1989
|
1.01
|
|
52
|
Macular oedema: the role of soluble mediators.
|
Br J Ophthalmol
|
2000
|
0.98
|
|
53
|
Intravitreal chemotactic and mitogenic activity. Implication of blood-retinal barrier breakdown.
|
Arch Ophthalmol
|
1986
|
0.98
|
|
54
|
TIMP-1 promotes VEGF-induced neovascularization in the retina.
|
Histol Histopathol
|
2001
|
0.96
|
|
55
|
An adenosine agonist and prostaglandin E1 cause breakdown of the blood-retinal barrier by opening tight junctions between vascular endothelial cells.
|
Invest Ophthalmol Vis Sci
|
1992
|
0.96
|
|
56
|
Isoforms of platelet-derived growth factor and its receptors in epiretinal membranes: immunolocalization to retinal pigmented epithelial cells.
|
Exp Eye Res
|
1995
|
0.95
|
|
57
|
Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype.
|
J Neurosci
|
1997
|
0.95
|
|
58
|
Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors.
|
Invest Ophthalmol Vis Sci
|
1998
|
0.95
|
|
59
|
Ultrastructural and immunocytochemical changes in retinal pigment epithelium, retinal glia, and fibroblasts in vitreous culture.
|
Invest Ophthalmol Vis Sci
|
1990
|
0.94
|
|
60
|
Retinal pigment epithelial cells release inhibitors of neovascularization.
|
Ophthalmology
|
1987
|
0.94
|
|
61
|
Aldose reductase expression in human diabetic retina and retinal pigment epithelium.
|
Diabetes
|
1988
|
0.94
|
|
62
|
Perfluoroperhydrophenanthrene versus perfluoro-n-octane in vitreoretinal surgery.
|
Ophthalmology
|
2000
|
0.93
|
|
63
|
Cryotherapy enhances intravitreal dispersion of viable retinal pigment epithelial cells.
|
Arch Ophthalmol
|
1985
|
0.92
|
|
64
|
Deletion (13)(q14.1q14.3) in two generations: variability of ocular manifestations and definition of the phenotype.
|
Am J Med Genet
|
1987
|
0.92
|
|
65
|
Localization of blood-retinal barrier breakdown in human pathologic specimens by immunohistochemical staining for albumin.
|
Lab Invest
|
1990
|
0.91
|
|
66
|
Cryotherapy during surgery for giant retinal tears and intravitreal dispersion of viable retinal pigment epithelial cells.
|
Ophthalmology
|
1993
|
0.91
|
|
67
|
Increased vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGFbeta) in experimental autoimmune uveoretinitis: upregulation of VEGF without neovascularization.
|
J Neuroimmunol
|
1998
|
0.91
|
|
68
|
Management of endophthalmitis in a silicone oil-filled eye.
|
Retina
|
1997
|
0.90
|
|
69
|
Intravitreous fibronectin and platelet-derived growth factor. New model for traction retinal detachment.
|
Arch Ophthalmol
|
1986
|
0.90
|
|
70
|
Successful treatment of gram-negative endophthalmitis with intravitreous ceftazidime.
|
Arch Ophthalmol
|
1992
|
0.90
|
|
71
|
Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularization.
|
Gene Ther
|
2003
|
0.90
|
|
72
|
Sustained expression after nonviral ocular gene transfer using mammalian promoters.
|
Gene Ther
|
2006
|
0.90
|
|
73
|
Immunohistochemical localization of blood-retinal barrier breakdown sites associated with post-surgical macular oedema.
|
Histochem J
|
1994
|
0.89
|
|
74
|
Human retinal pigment epithelial cells possess muscarinic receptors coupled to calcium mobilization.
|
Brain Res
|
1988
|
0.88
|
|
75
|
Electron microscopic immunocytochemical evidence for the mechanism of blood-retinal barrier breakdown in galactosemic rats and its association with aldose reductase expression and inhibition.
|
Exp Eye Res
|
1993
|
0.87
|
|
76
|
Class III beta-tubulin in human retinal pigment epithelial cells in culture and in epiretinal membranes.
|
Exp Eye Res
|
1995
|
0.87
|
|
77
|
Ultrastructural localization of blood-retinal barrier breakdown in diabetic and galactosemic rats.
|
J Histochem Cytochem
|
1990
|
0.86
|
|
78
|
Retinal vascular occlusion without retrobulbar or optic nerve sheath hemorrhage after retrobulbar injection of lidocaine.
|
Ophthalmic Surg
|
1988
|
0.86
|
|
79
|
Cell injury unmasks a latent proangiogenic phenotype in mice with increased expression of FGF2 in the retina.
|
J Cell Physiol
|
2000
|
0.86
|
|
80
|
The effect of oral 13-cis-retinoic acid on retinal redetachment after surgical repair in eyes with proliferative vitreoretinopathy.
|
Ophthalmology
|
1995
|
0.85
|
|
81
|
Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.
|
Am J Pathol
|
2000
|
0.85
|
|
82
|
Endothelial cells release a chemoattractant for retinal pigment epithelial cells in vitro.
|
Arch Ophthalmol
|
1985
|
0.85
|
|
83
|
Retinal pigment epithelial cells release an inhibitor of neovascularization.
|
Birth Defects Orig Artic Ser
|
1988
|
0.84
|
|
84
|
Human retinal pigment epithelial cells in culture possess A2-adenosine receptors.
|
Brain Res
|
1989
|
0.84
|
|
85
|
The role of breakdown of the blood-retinal barrier in cell-injection models of proliferative vitreoretinopathy.
|
Arch Ophthalmol
|
1988
|
0.84
|
|
86
|
Characterization of adenylate cyclase in human retinal pigment epithelial cells in vitro.
|
Exp Eye Res
|
1987
|
0.83
|
|
87
|
Neurotrophic factors, cytokines and stress increase expression of basic fibroblast growth factor in retinal pigmented epithelial cells.
|
Exp Eye Res
|
1997
|
0.83
|
|
88
|
Sequence and expression analysis of bovine pigment epithelium-derived factor.
|
Biochim Biophys Acta
|
1998
|
0.83
|
|
89
|
Progressive ultrastructural damage and thickening of the basement membrane of the retinal pigment epithelium in spontaneously diabetic BB rats.
|
Exp Eye Res
|
1988
|
0.82
|
|
90
|
A splice variant of trkB and brain-derived neurotrophic factor are co-expressed in retinal pigmented epithelial cells and promote differentiated characteristics.
|
Brain Res
|
1998
|
0.82
|
|
91
|
Implication of protein carboxymethylation in retinal pigment epithelial cell chemotaxis.
|
Ophthalmic Res
|
1988
|
0.81
|
|
92
|
Inhibition of growth factor effects in retinal pigment epithelial cells.
|
Invest Ophthalmol Vis Sci
|
1991
|
0.81
|
|
93
|
Simultaneous expression of keratin and glial fibrillary acidic protein by the same cells in epiretinal membranes.
|
Invest Ophthalmol Vis Sci
|
1992
|
0.81
|
|
94
|
Sensitivity of different vascular beds in the eye to neovascularization and blood-retinal barrier breakdown in VEGF transgenic mice.
|
Adv Exp Med Biol
|
2000
|
0.81
|
|
95
|
Electron microscopic immunocytochemical demonstration of blood-retinal barrier breakdown in human diabetics and its association with aldose reductase in retinal vascular endothelium and retinal pigment epithelium.
|
Histochem J
|
1993
|
0.80
|
|
96
|
Candidal endophthalmitis after lithotripsy of renal calculi.
|
South Med J
|
1992
|
0.80
|
|
97
|
A retina-derived stimulator(s) of retinal pigment epithelial cell and astrocyte proliferation.
|
Exp Eye Res
|
1986
|
0.80
|
|
98
|
Histopathological features of vitreous removed at macular hole surgery.
|
Arch Ophthalmol
|
1999
|
0.79
|
|
99
|
Evolution of morphologic changes after intravitreous injection of gentamicin.
|
Curr Eye Res
|
1993
|
0.79
|
|
100
|
Human retinal pigment epithelial cells possess V1 vasopressin receptors.
|
Curr Eye Res
|
1991
|
0.79
|
|
101
|
A morphological and immunohistochemical study of human retinal pigment epithelial cells, retinal glia, and fibroblasts grown on Gelfoam matrix in an organ culture system. A comparison of structural and nonstructural proteins and their application to cell type identification.
|
Graefes Arch Clin Exp Ophthalmol
|
1993
|
0.78
|
|
102
|
Dexamethasone and indomethacin attenuate cryopexy. Induced breakdown of the blood-retinal barrier.
|
Graefes Arch Clin Exp Ophthalmol
|
1987
|
0.78
|
|
103
|
Experimental models of growth factor-mediated angiogenesis and blood-retinal barrier breakdown.
|
Gen Pharmacol
|
2000
|
0.78
|
|
104
|
Thrombin is a stimulator of retinal pigment epithelial cell proliferation.
|
Exp Eye Res
|
1991
|
0.78
|
|
105
|
Stimulation of cyclic adenosine monophosphate accumulation causes breakdown of the blood-retinal barrier.
|
Invest Ophthalmol Vis Sci
|
1991
|
0.77
|
|
106
|
Intravitreous injection of adenosine or its agonists causes breakdown of the blood-retinal barrier.
|
Arch Ophthalmol
|
1989
|
0.76
|
|
107
|
Modulation of plasminogen activator inhibitor-1 and urokinase in retinal pigmented epithelial cells.
|
Invest Ophthalmol Vis Sci
|
1993
|
0.76
|
|
108
|
Mechanisms involved in retinal pigment epithelial cell chemotaxis.
|
Arch Ophthalmol
|
1986
|
0.76
|
|
109
|
Cyclic 3',5'-adenosine monophosphate modulates retinal pigment epithelial cell migration in vitro.
|
Arch Ophthalmol
|
1986
|
0.76
|
|
110
|
A retinal pigment epithelial cell-derived growth factor(s).
|
Arch Ophthalmol
|
1986
|
0.76
|
|
111
|
The Silicone Study. A small piece of the PVR puzzle is put into place.
|
Arch Ophthalmol
|
1997
|
0.76
|
|
112
|
Prevention or moderation of some ultrastructural changes in the RPE and retina of galactosemic rats by aldose reductase inhibition.
|
Exp Eye Res
|
1989
|
0.75
|
|
113
|
Oil and gas on troubled waters. The proliferative vitreoretinopathy studies.
|
Arch Ophthalmol
|
1992
|
0.75
|
|
114
|
Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro.
|
Arch Ophthalmol
|
1996
|
0.75
|
|
115
|
Cyclic 3',5'-adenosine monophosphate modulates vascular endothelial cell migration in vitro.
|
Cell Biol Int Rep
|
1987
|
0.75
|
|
116
|
High glucose concentrations inhibit protein synthesis in retinal pigment epithelium in vitro.
|
Exp Eye Res
|
1987
|
0.75
|
|
117
|
Ultrastructural localization of RPE-associated epitopes recognized by monoclonal antibodies in human RPE and their induction in human fibroblasts by vitreous.
|
Graefes Arch Clin Exp Ophthalmol
|
1993
|
0.75
|