PubRank

J Ghrayeb

Author PubWeight™ 91.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science 1999 21.24
2 HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope. Science 1986 6.33
3 Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 1993 5.05
4 Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J Virol 2001 3.40
5 Expression of the art/trs protein of HIV and study of its role in viral envelope synthesis. Science 1987 3.25
6 Secretion cloning vectors in Escherichia coli. EMBO J 1984 2.58
7 Human immunodeficiency virus: the eighth gene. AIDS Res Hum Retroviruses 1987 2.45
8 Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine 1995 2.34
9 Cytoplasmic localization of the HTLV-III 3' orf protein in cultured T cells. Virology 1986 2.25
10 A nonhuman primate model for the selective elimination of CD8+ lymphocytes using a mouse-human chimeric monoclonal antibody. Am J Pathol 1999 2.16
11 Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc Natl Acad Sci U S A 1989 2.15
12 Synthesis and secretion of multiple forms of beta 2-interferon/B-cell differentiation factor 2/hepatocyte-stimulating factor by human fibroblasts and monocytes. J Biol Chem 1988 1.80
13 Regulation of the acute phase and immune responses in viral disease. Enhanced expression of the beta 2-interferon/hepatocyte-stimulating factor/interleukin 6 gene in virus-infected human fibroblasts. J Exp Med 1988 1.74
14 IL-6/IFN-beta 2 in synovial effusions of patients with rheumatoid arthritis and other arthritides. Identification of several isoforms and studies of cellular sources. J Immunol 1989 1.56
15 Rapid, easy, and economical screening test for antibodies to human immunodeficiency virus. Lancet 1987 1.54
16 Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina. Eur J Immunol 1996 1.27
17 An HTLV-III peptide produced by recombinant DNA is immunoreactive with sera from patients with AIDS. Nature 1985 1.26
18 Nine amino acid residues at the NH2-terminal of lipoprotein are sufficient for its modification, processing, and localization in the outer membrane of Escherichia coli. J Biol Chem 1984 1.25
19 Biological activity of human-mouse IgG1, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity. Proc Natl Acad Sci U S A 1988 1.22
20 The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo. Cytokine 1995 1.17
21 Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A. Proc Natl Acad Sci U S A 1987 1.15
22 Human T-cell lymphotropic virus type III (HTLV-III) core antigens: synthesis in Escherichia coli and immunoreactivity with human sera. DNA 1986 1.07
23 Multiplicity strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes. Biochemistry 1982 1.06
24 Expression of the protein encoded by the 3' open reading frame of human T-cell lymphotropic virus type III in bacteria: demonstration of its immunoreactivity with human sera. Proc Natl Acad Sci U S A 1986 1.06
25 T-cell response towards HIV in infected individuals with and without zidovudine therapy, and in HIV-exposed sexual partners. AIDS 1989 1.05
26 The expression in Escherichia coli of recombinant human platelet factor 4, a protein with immunoregulatory activity. J Biol Chem 1988 1.00
27 The immunogenicity of the 7E3 murine monoclonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions. Mol Immunol 1995 0.99
28 Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4. Immunology 1995 0.98
29 Characterization of a mouse/human chimeric monoclonal antibody (17-1A) to a colon cancer tumor-associated antigen. J Immunol 1987 0.98
30 Wild type and mutant signal peptides of Escherichia coli outer membrane lipoprotein interact with equal efficiency with mammalian signal recognition particle. J Biol Chem 1987 0.96
31 Localization of B-cell stimulatory activity of HIV-1 to the carboxyl terminus of gp41. AIDS Res Hum Retroviruses 1990 0.96
32 Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis. Arthritis Rheum 1993 0.95
33 Lipopolysaccharide (LPS) neutralizing peptides reveal a lipid A binding site of LPS binding protein. J Biol Chem 1995 0.94
34 Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 1995 0.93
35 Phosphorylation of secreted forms of human beta 2-interferon/hepatocyte stimulating factor/interleukin-6. Biochem Biophys Res Commun 1988 0.92
36 Chimeric antibodies with 17-1A-derived variable and human constant regions. Hybridoma 1986 0.91
37 Functional comparisons of different tumour necrosis factor receptor/IgG fusion proteins. Cytokine 1995 0.88
38 Multiple forms of human interleukin-6. Phosphoglycoproteins secreted by many different tissues. Ann N Y Acad Sci 1989 0.87
39 An alternate pathway for the processing of the prolipoprotein signal peptide in Escherichia coli. J Biol Chem 1985 0.86
40 Post-translational modifications of human interleukin-6. Arch Biochem Biophys 1989 0.86
41 TNF receptor fusion proteins are effective inhibitors of TNF-mediated cytotoxicity on human KYM-1D4 rhabdomyosarcoma cells. Cytokine 1994 0.85
42 Expression and characterization of cM-T413, a chimeric anti-CD4 antibody with in vitro immunosuppressive activity. J Immunother Emphasis Tumor Immunol 1994 0.84
43 Human lymphocyte and monocyte lysis of tumor cells mediated by a mouse/human IgG1 chimeric monoclonal antibody. J Biol Response Mod 1988 0.83
44 Apolipoprotein, an intermediate in the processing of the major lipoprotein of the Escherichia coli outer membrane. J Biol Chem 1984 0.82
45 Proalbumin is bound to the membrane of rat liver smooth microsomes. Biochem Biophys Res Commun 1980 0.82
46 Biological characterization of a chimeric mouse-human IgM antibody directed against the 17-1A antigen. Cancer Immunol Immunother 1989 0.79
47 Neutralization of TNF by the antibody cA2 reveals differential regulation of adhesion molecule expression on TNF-activated endothelial cells. Cell Adhes Commun 1998 0.78
48 Minimal tumor necrosis factor receptor binding protein: optimum biological activity of a truncated p55 soluble tumor necrosis factor receptor-IgG fusion protein. Eur Cytokine Netw 1998 0.76
49 Stable expression of cloned human antibody genes in murine myeloma cells. Hum Antibodies Hybridomas 1992 0.75
50 High-level expression and characterization of a mouse-human chimeric CD4 antibody with therapeutic potential. Hum Antibodies Hybridomas 1992 0.75
51 Effects of isotype and Fc region on in vitro function of a mouse/human chimeric CD4 antibody. Int Immunol 1993 0.75
52 Pharmacokinetics of a mouse/human chimeric monoclonal antibody (C-17-1A) in metastatic adenocarcinoma patients. Pharm Res 1990 0.75
53 Nonrandom distribution of antibodies to the TRS protein of human immunodeficiency virus in infected people with different clinical status. AIDS Res Hum Retroviruses 1988 0.75