W K Yung

Author PubWeight™ 149.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997 15.38
2 The somatic genomic landscape of glioblastoma. Cell 2013 11.73
3 Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol 1999 8.69
4 MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res 1997 3.38
5 A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 2000 2.81
6 The development and psychometric validation of a brain cancer quality-of-life questionnaire for use in combination with general cancer-specific questionnaires. Qual Life Res 1996 2.76
7 Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 2000 2.22
8 Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res 1999 1.95
9 Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. Cancer Res 1999 1.88
10 Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis. Cancer Res 1999 1.66
11 Cognitive function as a predictor of survival in patients with recurrent malignant glioma. J Clin Oncol 2000 1.66
12 Response and progression in recurrent malignant glioma. Neuro Oncol 1999 1.57
13 Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res 1998 1.52
14 Outcome and patterns of failure following limited-volume irradiation for malignant astrocytomas. Radiother Oncol 1991 1.47
15 Suppression of human glioma growth by adenovirus-mediated Rb gene transfer. Neurology 1998 1.46
16 Isolation, karyotype, and clonal growth of heterogeneous subpopulations of human malignant gliomas. Cancer Res 1981 1.44
17 Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme. Int J Radiat Oncol Biol Phys 1995 1.41
18 The autocrine loop of TGF-alpha/EGFR and brain tumors. J Neurooncol 1997 1.40
19 The use of significant others as proxy raters of the quality of life of patients with brain cancer. Med Care 1997 1.37
20 Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. J Clin Oncol 2000 1.35
21 Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res 1999 1.28
22 Effect of disease burden on health-related quality of life in patients with malignant gliomas. Neuro Oncol 2000 1.27
23 Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis. Cancer Res 1996 1.21
24 Two tumor suppressive loci on chromosome 10 involved in human glioblastomas. Genes Chromosomes Cancer 1995 1.21
25 Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide. Eur J Cancer 2000 1.19
26 A reliability test of standard-based quantitative PCR: exogenous vs endogenous standards. Mol Cell Probes 2000 1.18
27 Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nat Med 1998 1.18
28 Analysis of the functional role of chromosome 10 loss in human glioblastomas. Cancer Res 1993 1.15
29 Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene 2001 1.14
30 An intermediate filament-associated protein, p50, recognized by monoclonal antibodies. J Cell Biol 1983 1.11
31 Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2. Cancer Res 2001 1.07
32 Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis. J Natl Cancer Inst 1997 1.07
33 Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma. Oncogene 1997 1.06
34 Heterogeneous chemosensitivities of subpopulations of human glioma cells in culture. Cancer Res 1982 1.05
35 Capecitabine for 5-fluorouracil-resistant brain metastases from breast cancer. Am J Clin Oncol 2001 1.03
36 Altered expression and distribution of heparan sulfate proteoglycans in human gliomas. Cancer Res 1989 1.02
37 Clinical trial end points in malignant glioma: need for effective trial design strategy. Semin Oncol 2000 1.01
38 Effect of neurological dysfunction on health-related quality of life in patients with high-grade glioma. J Neurooncol 1997 0.99
39 Use of [18F]fluorodeoxyglucose positron emission tomography in patients with primary malignant brain tumors. Ann Neurol 1993 0.99
40 Vimentin and glial fibrillary acidic protein in human brain tumors. J Neurooncol 1985 0.99
41 The treatment of recurrent unresectable and malignant meningiomas with interferon alpha-2B. Neurosurgery 1997 0.98
42 Expression of an altered epidermal growth factor receptor by human glioblastoma cells. Cancer Res 1988 0.98
43 Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998. Neuro Oncol 2001 0.98
44 Growth inhibitory effects of interferon-beta but not interferon-alpha on human glioma cells: correlation of receptor binding, 2',5'-oligoadenylate synthetase and protein kinase activity. J Interferon Res 1990 0.98
45 Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. J Biol Chem 2001 0.97
46 Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells. Clin Cancer Res 2001 0.97
47 Efficient inhibition of in vivo human malignant glioma growth and angiogenesis by interferon-beta treatment at early stage of tumor development. Clin Cancer Res 2000 0.95
48 Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas. Cancer Res 1997 0.95
49 The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin). J Neurooncol 1997 0.95
50 Imaging patterns of multifocal gliomas. Eur J Radiol 1993 0.94
51 The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity in human glioma cell lines. Clin Cancer Res 2000 0.94
52 Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells. Oncogene 1996 0.93
53 Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades. Clin Exp Metastasis 2000 0.93
54 Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance. Clin Cancer Res 1998 0.92
55 Functional and molecular analyses of 10q deletions in human gliomas. Genes Chromosomes Cancer 1999 0.91
56 Central nervous system toxicity with high-dose Ara-C. Neurology 1985 0.91
57 TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors. J Clin Oncol 1997 0.91
58 Differentiation of residual or recurrent tumors from post-treatment changes with F-18 FDG PET. Radiographics 1992 0.91
59 Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro. Oncogene 1997 0.90
60 Diffuse bone marrow metastasis by glioblastoma: premortem diagnosis by peroxidase-antiperoxidase staining for glial fibrillary acidic protein. Ann Neurol 1983 0.90
61 The treatment of anaplastic oligodendrogliomas and mixed gliomas. Neurosurgery 1993 0.90
62 MR of toxic effects of accelerated fractionation radiation therapy and carboplatin chemotherapy for malignant gliomas. AJNR Am J Neuroradiol 1995 0.89
63 Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. Clin Cancer Res 2001 0.88
64 Advances in chemotherapy for brain tumors. Neurol Clin 1995 0.88
65 Toward a molecular classification of the gliomas: histopathology, molecular genetics, and gene expression profiling. Histol Histopathol 2000 0.88
66 Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas. Oncogene 1996 0.87
67 Prognostic significance of p53 immunoreactivity in patients with glioma. Clin Cancer Res 1995 0.87
68 A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme. Int J Radiat Oncol Biol Phys 1999 0.87
69 All-trans-retinoic acid: a phase II Radiation Therapy Oncology Group study (RTOG 91-13) in patients with recurrent malignant astrocytoma. J Neurooncol 1997 0.86
70 Delivery of cell cycle genes to block astrocytoma growth. J Neurooncol 2001 0.85
71 Irinotecan: promising activity in the treatment of malignant glioma. Oncology (Williston Park) 2003 0.85
72 Inhibition of breast cancer growth in vivo by antiangiogenesis gene therapy with adenovirus-mediated antisense-VEGF. Br J Cancer 2001 0.85
73 'Glioblastoma'. Induction of a reproducible autochonous tumor in rats with murine sarcoma virus. Neurology 1976 0.84
74 Correlation between dynamic MRI and outcome in patients with malignant gliomas. Neurology 1998 0.84
75 Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis. Neuro Oncol 2001 0.84
76 Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses. Exp Cell Res 1999 0.84
77 Expression of epidermal growth factor receptor and associated glycoprotein on cultured human brain tumor cells. J Cell Biochem 1986 0.83
78 Two primitive neuroectodermal tumor cell lines require an activated insulin-like growth factor I receptor for growth in vitro. Neurosurgery 1996 0.83
79 Adenovirus-mediated p53 gene therapy for human gliomas. Neurosurgery 1999 0.83
80 Treatment of recurrent gliomas with eflornithine. J Natl Cancer Inst 1992 0.83
81 Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336. Neuro Oncol 2000 0.82
82 Growth regulatory activities of endothelial extracellular matrix: mediation by transforming growth factor-beta. Exp Cell Res 1990 0.82
83 Targeting in gene therapy for gliomas. Arch Neurol 1999 0.81
84 Intracarotid infusion of cis-diamminedichloroplatinum in the treatment of recurrent malignant brain tumors. Cancer 1984 0.81
85 Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth. J Neurooncol 1999 0.81
86 Multifocal cerebral gliomas associated with secondary malignancies. Lancet 1992 0.80
87 A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients. J Neurooncol 2016 0.80
88 A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes. Int J Oncol 1998 0.79
89 Gamma-ray mutagen sensitivity and survival in patients with glioma. Clin Cancer Res 1998 0.79
90 Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells. Mol Carcinog 1999 0.79
91 Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas. Neurosurgery 1996 0.79
92 Co-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells. Int J Oncol 2001 0.78
93 Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene. J Neurosurg 1998 0.78
94 The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies. Neurology 1998 0.78
95 Resolution of recurrent malignant ganglioglioma after treatment with cis-retinoic acid. J Neurooncol 1996 0.78
96 Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy. Int J Oncol 1998 0.78
97 Inhibition of epidermal growth factor receptor activity by retinoic acid in glioma cells. J Cell Biochem 1990 0.78
98 Phase II trial of mitogauzone in malignant primary brain tumors. Cancer Treat Rep 1985 0.78
99 Factors influencing the mode of delivery and associated pregnancy outcomes for twins: a retrospective cohort study in a public hospital. Hong Kong Med J 2012 0.78
100 Delayed neurotoxicity of intraventricular interleukin-2: a case report. J Neurooncol 1993 0.77
101 Chemotherapy with dexamethasone, high-dose cytarabine, and cisplatin for parenchymal brain lymphoma. J Natl Cancer Inst 1988 0.77
102 Glioblastoma multiforme: treatment with radiation and triiodothyronine. Int J Radiat Oncol Biol Phys 1977 0.77
103 Intracarotid VP-16 in malignant brain tumors. J Neurooncol 1987 0.77
104 Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis. Int J Mol Med 1999 0.77
105 Anguidine potentiates cis-platinum in human brain tumor cells. J Neurooncol 1986 0.77
106 The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen. J Neurooncol 1989 0.77
107 New drugs and new delivery techniques. Prog Exp Tumor Res 1985 0.76
108 Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma. Oncogene 1997 0.76
109 High dose Ara-C related leukoencephalopathy. J Neurooncol 1986 0.76
110 Phase II trial of intracarotid BCNU and cisplatin in primary malignant brain tumors. Cancer Drug Deliv 1986 0.76
111 Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells. Genes Chromosomes Cancer 1997 0.76
112 Potentials and limitations of adenovirus-p53 gene therapy for brain tumors. J Korean Med Sci 2000 0.76
113 Phase-I trial of intracarotid BCNU and cisplatin in patients with malignant intracerebral tumors. Cancer Drug Deliv 1984 0.76
114 BUdR radiosensitization in anaplastic astrocytoma. Int J Radiat Oncol Biol Phys 1999 0.75
115 Modulation of serine proteinases and metalloproteinases during morphogenic glial-endothelial interactions. J Neurochem 1996 0.75
116 Assessing response to chemotherapy in malignant glioma: the role of steroids. Neurology 1998 0.75
117 In vitro effects of ACNU, BCNU, CDDP, and bleomycin on human glioma cells. Neurol Med Chir (Tokyo) 1988 0.75
118 Radiation Therapy Oncology Group. Research Plan 2002-2006. Medical Oncology Committee. Int J Radiat Oncol Biol Phys 2001 0.75
119 A frequent polymorphism in exon 1 of the p16/CDKN2 gene. Mol Cell Probes 1995 0.75
120 A phase II trial of 2,5,-diaziridinyl 3,6-bis (carboethoxy amino) 1,4-benzoquinone (AZQ, NSC 182986) in recurrent primary brain tumors. J Neurooncol 1984 0.75
121 Regional nerve injury after intra-arterial chemotherapy. Neurology 1987 0.75
122 Radiation Therapy Oncology Group. Research Plan 2002-2006. Brain Tumor Committee. Int J Radiat Oncol Biol Phys 2001 0.75
123 Meningeal gliomatosis: a review of twelve cases. Trans Am Neurol Assoc 1979 0.75
124 A pilot study of cis-diamminedichloroplatinum and radiation therapy in patients with high grade astrocytomas. J Neurooncol 1983 0.75
125 Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity. J Neurovirol 1998 0.75
126 Molecular genetics and tumour suppressor genes in gliomas. Baillieres Clin Neurol 1996 0.75
127 Planned conservative management of placenta accreta - experience of a regional general hospital. J Matern Fetal Neonatal Med 2013 0.75
128 Altered expression of glycosaminoglycans in metastatic 13762NF rat mamma adenocarcinoma cells. Biochemistry 1987 0.75
129 DNA synthesis in fast- and slow-growing C57BL ascites tumors. Cancer Res 1974 0.75
130 Brain and meningeal biopsy in patients with acquired immunodeficiency syndrome. Tex Med 1986 0.75
131 Neurotoxicity of high-dose Ara-C and intracarotid chemotherapy. Prog Exp Tumor Res 1985 0.75