Published in J Virol on July 01, 1999
Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector. J Virol (2000) 2.63
Dependence of adenovirus infectivity on length of the fiber shaft domain. J Virol (2000) 2.14
The first step of adenovirus type 2 disassembly occurs at the cell surface, independently of endocytosis and escape to the cytosol. J Virol (2000) 1.95
Current advances and future challenges in Adenoviral vector biology and targeting. Curr Gene Ther (2007) 1.94
Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein. J Virol (2001) 1.70
Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3. EMBO J (2008) 1.59
Adenovirus receptors. J Virol (2005) 1.55
The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses. J Virol (2003) 1.49
Cytoplasmic dynein mediates adenovirus binding to microtubules. J Virol (2004) 1.36
Cytoplasmic trafficking of the canine parvovirus capsid and its role in infection and nuclear transport. J Virol (2000) 1.34
Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs. J Virol (2005) 1.31
Genetically targeted adenovirus vector directed to CD40-expressing cells. J Virol (2003) 1.18
Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses (2010) 1.17
Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner. J Virol (2004) 1.15
Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber. J Virol (2003) 1.13
Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. J Virol (2007) 1.13
Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses. J Virol (2004) 1.11
Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX. J Virol (2004) 1.08
Surface loop dynamics in adeno-associated virus capsid assembly. J Virol (2008) 1.04
Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome. Virology (2011) 0.98
Infectious virions produced from a human papillomavirus type 18/16 genomic DNA chimera. J Virol (2002) 0.98
Gene transduction and cell entry pathway of fiber-modified adenovirus type 5 vectors carrying novel endocytic peptide ligands selected on human tracheal glandular cells. J Virol (2004) 0.97
Adenovirus type-5 entry and disassembly followed in living cells by FRET, fluorescence anisotropy, and FLIM. Biophys J (2004) 0.95
Association of adenovirus with the microtubule organizing center. J Virol (2003) 0.95
Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors. Mol Ther (2009) 0.95
Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis. PLoS One (2008) 0.93
A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes. J Virol (2006) 0.93
Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells. J Virol (2004) 0.93
Adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2. J Virol (2001) 0.92
Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway. J Virol (2006) 0.92
Adenovirus dodecahedron allows large multimeric protein transduction in human cells. J Virol (2003) 0.92
Core labeling of adenovirus with EGFP. Virology (2006) 0.91
Improved gene delivery to intestinal mucosa by adenoviral vectors bearing subgroup B and d fibers. J Virol (2006) 0.89
Adenovirus recruits dynein by an evolutionary novel mechanism involving direct binding to pH-primed hexon. Viruses (2011) 0.88
Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction. PLoS One (2011) 0.87
Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5-based Constructs. Mol Ther (2015) 0.87
Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. J Virol (2014) 0.86
Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol (2014) 0.86
Microtubule-mediated and microtubule-independent transport of adenovirus type 5 in HEK293 cells. J Virol (2007) 0.85
The amphipathic helix of adenovirus capsid protein VI contributes to penton release and postentry sorting. J Virol (2014) 0.82
Adenovirus membrane penetration: Tickling the tail of a sleeping dragon. Virology (2015) 0.81
Development of adenovirus capsid proteins for targeted therapeutic delivery. Ther Deliv (2013) 0.79
Emerging roles for ubiquitin in adenovirus cell entry. Biol Cell (2012) 0.77
Human papillomavirus type 18 chimeras containing the L2/L1 capsid genes from evolutionarily diverse papillomavirus types generate infectious virus. Virus Res (2011) 0.76
Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron. PLoS One (2012) 0.76
Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses (2014) 0.76
Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking. Viruses (2014) 0.76
Influence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35. Sci Rep (2016) 0.75
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science (1997) 14.41
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell (1993) 13.21
Endocytosis. Physiol Rev (1997) 7.33
HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci U S A (1997) 6.92
Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell (1984) 6.50
Stepwise dismantling of adenovirus 2 during entry into cells. Cell (1993) 6.34
Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo. Science (1991) 6.28
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell (1992) 5.85
Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J Virol (1996) 4.97
Virus-receptor interaction in an adenovirus system. J Virol (1968) 4.69
Human adenovirus-host cell interactions: comparative study with members of subgroups B and C. J Virol (1990) 4.32
Transfer of genes to humans: early lessons and obstacles to success. Science (1995) 3.64
Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells. J Virol (1993) 3.29
Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues. J Virol (1996) 3.01
An electron microscope study of the early association between two mammalian viruses and their hosts. J Cell Biol (1962) 2.99
Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types. Nat Biotechnol (1996) 2.69
Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J Virol (1997) 2.64
Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J (1998) 2.63
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J Virol (1996) 2.52
Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol (1996) 2.46
The role of the adenovirus protease on virus entry into cells. EMBO J (1996) 2.44
Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J Virol (1995) 2.41
Early events in the interaction of adenoviruses with HeLa cells. I. Penetration of type 5 and intracellular release of the DNA genome. Virology (1970) 2.40
Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells. J Virol (1996) 2.38
The role of the nuclear pore complex in adenovirus DNA entry. EMBO J (1997) 2.37
Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther (1998) 2.27
Adenoviruses as gene-delivery vehicles. N Engl J Med (1996) 2.20
Targeted gene delivery by tropism-modified adenoviral vectors. Nat Biotechnol (1996) 2.14
Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway. J Virol (1995) 2.05
Adenovirus-mediated gene transfer to ciliated airway epithelia requires prolonged incubation time. J Virol (1996) 1.98
Human adenovirus serotypes 3 and 5 bind to two different cellular receptors via the fiber head domain. J Virol (1995) 1.88
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J Virol (1998) 1.88
Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol (1996) 1.85
Role of vesicles during adenovirus 2 internalization into HeLa cells. J Virol (1985) 1.81
Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein. J Virol (1997) 1.79
Adenovirus internalization and infection require dynamin. J Virol (1998) 1.78
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A (1993) 1.72
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector. Nat Biotechnol (1997) 1.66
Virus-receptor interaction in the adenovirus system: characterization of the positive cooperative binding of virions on HeLa cells. J Virol (1985) 1.52
Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector. Gene Ther (1995) 1.44
Chromosomal organization of the herpes simplex virus genome during acute infection of the mouse central nervous system. J Virol (1986) 1.41
Early events in the interaction of adenoviruses with HeLa cells. II. Comparative observations on the penetration of types 1, 5, 7, and 12. Virology (1970) 1.22
Nuclear targeting of SV40 and adenovirus. Trends Cell Biol (1996) 1.19
Efficient adenovirus-mediated gene transfer to basal but not columnar cells of cartilaginous airway epithelia. Hum Gene Ther (1996) 1.16
Targeted adenovirus-mediated gene delivery to T cells via CD3. J Virol (1997) 1.09
Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor. Cancer Res (1997) 1.08
Construction of an adenovirus type 7a E1A- vector. J Virol (1997) 1.04
Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. Am J Respir Cell Mol Biol (1999) 0.99
Use of a novel cross-linking method to modify adenovirus tropism. Gene Ther (1997) 0.91
High-efficiency gene transfer into ex vivo expanded human hematopoietic progenitors and precursor cells by adenovirus vectors. Blood (1998) 0.90
Early events in the infection process of adenovirus type 5 in HeLa cells. Virology (1967) 0.85
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med (2001) 9.53
Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J Appl Physiol (1985) (1986) 6.86
Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am J Pathol (1979) 5.94
Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation. Nature (1992) 5.45
Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann Intern Med (1976) 4.85
Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. J Clin Invest (1977) 4.21
Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. N Engl J Med (1981) 4.02
Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts). N Engl J Med (1984) 3.73
Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons. Proc Natl Acad Sci U S A (1984) 3.67
Normal alveolar epithelial lining fluid contains high levels of glutathione. J Appl Physiol (1985) (1987) 3.51
Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis. J Clin Invest (1985) 3.40
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38
Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med (2001) 3.25
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA. Nat Genet (1993) 3.22
Interstitial lung disease: current concepts of pathogenesis, staging and therapy. Am J Med (1981) 3.08
Systemic glutathione deficiency in symptom-free HIV-seropositive individuals. Lancet (1989) 3.01
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood (2001) 3.01
Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity. Nature (1986) 2.94
Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema. N Engl J Med (1987) 2.81
Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. Am J Respir Cell Mol Biol (2000) 2.81
Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. N Engl J Med (1983) 2.71
Respiratory disease rates and pulmonary function in children associated with NO2 exposure. Am Rev Respir Dis (1980) 2.63
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum Gene Ther (1997) 2.62
Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis. N Engl J Med (1987) 2.62
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J Clin Invest (1992) 2.62
A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis. N Engl J Med (1992) 2.57
Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol (1996) 2.46
Evaluation of clinical parameters to predict Mycobacterium tuberculosis in inpatients. Arch Intern Med (2000) 2.46
Gene therapy strategies for tumor antiangiogenesis. J Natl Cancer Inst (1998) 2.44
Molecular basis of alpha-1-antitrypsin deficiency. Am J Med (1988) 2.40
Bronchoalveolar lavage in interstitial lung disease. Ann Intern Med (1978) 2.36
Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Proc Natl Acad Sci U S A (1981) 2.34
Human alveolar macrophage growth factor for fibroblasts. Regulation and partial characterization. J Clin Invest (1982) 2.33
Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor. J Clin Invest (1992) 2.33
Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract. N Engl J Med (1984) 2.30
Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell (1985) 2.29
Human type III collagen gene expression is coordinately modulated with the type I collagen genes during fibroblast growth. Biochemistry (1986) 2.28
Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. J Clin Invest (1983) 2.27
Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther (1998) 2.27
Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. Am J Respir Crit Care Med (1994) 2.26
Interleukin-8 gene expression in human bronchial epithelial cells. J Biol Chem (1991) 2.26
Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse beta-globin (major) gene. Nucleic Acids Res (1984) 2.24
Rapid, nonradioactive detection of mutations in the human genome by allele-specific amplification. J Lab Clin Med (1989) 2.22
Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. Science (1979) 2.20
Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema. J Clin Invest (1981) 2.20
Accurate quantification of cells recovered by bronchoalveolar lavage. Am Rev Respir Dis (1984) 2.17
Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis. N Engl J Med (1979) 2.13
Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity. J Exp Med (1997) 2.12
Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis. Proc Natl Acad Sci U S A (1991) 2.12
Intraluminal fibrosis in interstitial lung disorders. Am J Pathol (1986) 2.10
Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis. J Clin Invest (1981) 2.10
Maintenance of granuloma formation in pulmonary sarcoidosis by T lymphocytes within the lung. N Engl J Med (1980) 2.07
Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. Lancet (1991) 2.05
Human alveolar macrophage-derived chemotactic factor for neutrophils. Stimuli and partial characterization. J Clin Invest (1980) 2.04
Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol (1995) 2.02
Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog. J Clin Invest (1999) 2.02
Increased vascular permeability produced by human platelet granule cationic extract. J Clin Invest (1970) 1.98
Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther (2000) 1.97
Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers. Am Rev Respir Dis (1983) 1.97
Characterization of hematopoietic cells arising on the textured surface of left ventricular assist devices. Ann Thorac Surg (1995) 1.96
Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders. Lab Invest (1979) 1.94
Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood (1995) 1.94
Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J Immunol (1985) 1.92
DNA sequence of a small plasmid from Halobacterium strain GN101. Nucleic Acids Res (1989) 1.91
Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood (1994) 1.90
Familial idiopathic pulmonary fibrosis. Evidence of lung inflammation in unaffected family members. N Engl J Med (1986) 1.90
Systemic deficiency of glutathione in cystic fibrosis. J Appl Physiol (1985) (1993) 1.88
Granulocyte collagenase: selective digestion of type I relative to type III collagen. Proc Natl Acad Sci U S A (1977) 1.86
The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther (1994) 1.82
Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation (1999) 1.82
Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. J Clin Invest (1986) 1.82
Neurological deterioration in late infantile neuronal ceroid lipofuscinosis. Neurology (2007) 1.80
Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. J Clin Invest (1986) 1.80
Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science (1981) 1.80
The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function. Am Rev Respir Dis (1983) 1.76
Localization of the immune response in sarcoidosis. Am Rev Respir Dis (1979) 1.74
Sphingomyelinase treatment induces ATP-independent endocytosis. J Cell Biol (1998) 1.72
Iodination of the human platelet membrane. Studies of the major surface glycoprotein. J Biol Chem (1973) 1.72
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A (1993) 1.72
Control of collagen production by human diploid lung fibroblasts. J Biol Chem (1980) 1.72
Alveolitis: the key to the interstitial lung disorders. Thorax (1982) 1.71
"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype. Hum Gene Ther (1996) 1.70
The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin. J Biol Chem (1991) 1.70
Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein. J Virol (2001) 1.70
Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung. J Clin Invest (1984) 1.68
Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis (1979) 1.67
Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1. Ann N Y Acad Sci (2001) 1.67
Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J Clin Invest (1987) 1.64