N J Klein

Author PubWeight™ 65.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Infection and sudden unexpected death in infancy: a systematic retrospective case review. Lancet 2008 3.44
2 Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition. Infect Immun 2000 2.71
3 Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease. Br J Surg 2012 2.61
4 Deficiency of mannose-binding lectin and burden of infection in children with malignancy: a prospective study. Lancet 2001 2.60
5 Management of Kawasaki disease. Arch Dis Child 2013 2.30
6 Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis. Immunol Rev 2001 1.90
7 Disruption of sulphated glycosaminoglycans in intestinal inflammation. Lancet 1993 1.64
8 Mannose-binding lectin is present in the infected airway: a possible pulmonary defence mechanism. Thorax 2008 1.54
9 Endotoxin immunity and the development of the systemic inflammatory response syndrome in critically ill children. Intensive Care Med 2006 1.52
10 Emergency management of meningitis. J R Soc Med 2000 1.49
11 Autoimmune enteropathy with distinct mucosal features in T-cell activation deficiency: the contribution of T cells to the mucosal lesion. J Pediatr Gastroenterol Nutr 1999 1.47
12 Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitidis serogroup B. J Infect Dis 2001 1.35
13 Activation of complement by mannose-binding lectin on isogenic mutants of Neisseria meningitidis serogroup B. J Immunol 1998 1.13
14 Whole blood model of meningococcal bacteraemia--a method for exploring host-bacterial interactions. Microb Pathog 1995 1.07
15 Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing. Br J Haematol 1999 1.07
16 Poststreptococcal acute disseminated encephalomyelitis with basal ganglia involvement and auto-reactive antibasal ganglia antibodies. Ann Neurol 2001 1.06
17 The lipopolysaccharide structures of Salmonella enterica serovar Typhimurium and Neisseria gonorrhoeae determine the attachment of human mannose-binding lectin to intact organisms. Infect Immun 2000 1.03
18 Assessment of immune response to meningococcal disease: comparison of a whole-blood assay and the serum bactericidal assay. Microb Pathog 1999 1.02
19 Deficiency of prostacyclin production in meningococcal shock. Arch Dis Child 1991 1.01
20 Platelet and leucocyte activation in childhood sickle cell disease: association with nocturnal hypoxaemia. Br J Haematol 2000 1.01
21 Endothelial injury and repair in systemic vasculitis of the young. Arthritis Rheum 2010 0.97
22 Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes. Immunology 2000 0.96
23 Randomised controlled trial of inhaled corticosteroids (fluticasone propionate) in cystic fibrosis. Arch Dis Child 1997 0.93
24 Upregulation of intercellular adhesion molecule-1 expression on human endothelial cells by tumour necrosis factor-alpha in an in vitro model of the blood-brain barrier. Brain Res 1999 0.92
25 Early production of macrophage inflammatory protein-1 alpha occurs in respiratory distress syndrome and is associated with poor outcome. Pediatr Res 1996 0.92
26 Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS. Gastroenterology 2000 0.91
27 Effect of cytochalasin B on the biphasic release of insulin in perifused rat islets. Endocrinology 1973 0.91
28 Thromboembolic disease in systemic vasculitis is associated with enhanced microparticle-mediated thrombin generation. J Thromb Haemost 2011 0.90
29 Severe combined immunodeficiency with abnormalities in expression of the common leucocyte antigen, CD45. Arch Dis Child 1997 0.87
30 Severe meningococcal disease is characterized by early neutrophil but not platelet activation and increased formation and consumption of platelet-neutrophil complexes. J Leukoc Biol 2003 0.86
31 Total parenteral nutrition directly impairs cytokine production after bacterial challenge. J Pediatr Surg 1999 0.86
32 Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: an ex vivo human organ culture study. Inflamm Bowel Dis 2010 0.85
33 Platelet satellitism. N Engl J Med 1998 0.85
34 Induction of human endothelial tissue factor expression by Neisseria meningitidis: the influence of bacterial killing and adherence to the endothelium. Microb Pathog 1997 0.85
35 Susceptibility to infection in patients with neutropenia: the role of the innate immune system. Br J Haematol 2005 0.85
36 High-level endothelial E-selectin (CD62E) cell adhesion molecule expression by a lipopolysaccharide-deficient strain of Neisseria meningitidis despite poor activation of NF-kappaB transcription factor. Clin Exp Immunol 2004 0.84
37 Bactericidal activity against coagulase-negative staphylococci is impaired in infants receiving long-term parenteral nutrition. Ann Surg 2000 0.84
38 Investigation of platelet-neutrophil interactions in whole blood by flow cytometry. J Immunol Methods 1997 0.83
39 Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay. Thromb Res 1992 0.83
40 Potential Trace Metal Co-Limitation Controls on N2 Fixation and [Formula: see text] Uptake in Lakes with Varying Trophic Status. Front Microbiol 2013 0.82
41 Differential recognition of obligate anaerobic bacteria by human mannose-binding lectin. Clin Exp Immunol 2001 0.81
42 Congenital enterocyte heparan sulphate deficiency with massive albumin loss, secretory diarrhoea, and malnutrition. Lancet 1996 0.81
43 Neutrophil response to Neisseria meningitidis: inhibition of adhesion molecule expression and phagocytosis by recombinant bactericidal/permeability-increasing protein (rBPI21). J Infect Dis 1999 0.81
44 Gut overgrowth with abnormal flora: the missing link in parenteral nutrition-related sepsis in surgical neonates. Eur J Clin Nutr 2003 0.81
45 Interleukin-4 increases the permeability of human endothelial cells in culture. Clin Exp Allergy 2004 0.80
46 Mannose-binding lectin accelerates complement activation and increases serum killing of Neisseria meningitidis serogroup C. J Infect Dis 2001 0.80
47 Inflammatory mediators in human renal dysplasia. Nephrol Dial Transplant 2000 0.80
48 Detection of fibronectin expression by human endothelial cells using a enzyme-linked immunosorbent assay (ELISA): enzymatic degradation by activated plasminogen. J Immunol Methods 1997 0.80
49 MBL2 deficiency is associated with higher genomic bacterial loads during meningococcemia in young children. Clin Microbiol Infect 2014 0.79
50 The link between rotavirus vaccination and intussusception: implications for vaccine strategies. Gut 2002 0.79
51 Mucosal tumor necrosis factor-alpha production and extensive disruption of sulfated glycosaminoglycans begin within hours of birth in neonatal respiratory distress syndrome. Pediatr Res 1996 0.78
52 Staphylococcal toxins in sudden unexpected death in infancy: experience from a single specialist centre. Forensic Sci Med Pathol 2010 0.77
53 Absence of platelet CD40L identifies patients with X-linked hyper IgM syndrome. Clin Exp Immunol 2000 0.77
54 Tumor necrosis factor-alpha inhibits epithelial differentiation and morphogenesis in the mouse metanephric kidney in vitro. Int J Dev Biol 1998 0.76
55 Modulation of the endothelial procoagulant response to lipopolysaccharide and tumour necrosis factor-alpha in-vitro: the effects of dexamethasone, pentoxifylline, iloprost and a polyclonal anti-human IL-1 alpha antibody. Inflamm Res 1995 0.76
56 Interactions of meningococci with endothelium. Methods Mol Med 2001 0.76
57 Asthma in the developing world. Pediatr Ann 1999 0.75
58 Mechanisms of pulmonary hypertension in Bordetella pertussis. Arch Dis Child 2003 0.75
59 Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis. Arch Dis Child 1992 0.75
60 Peter Paul Rickham Prize--1998. Neutrophil dysfunction the cellular mechanism of impaired immunity during total parenteral nutrition in infancy. J Pediatr Surg 1999 0.75
61 Decreased monocyte class II MHC expression following major abdominal surgery in children is related to operative stress. Pediatr Surg Int 2006 0.75
62 Relationship of diapers to diaper rash. J Pediatr 1980 0.75