PubRank

H V Aposhian

Author PubWeight™ 69.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Arsenic: health effects, mechanisms of actions, and research issues. Environ Health Perspect 1999 3.07
2 DMSA and DMPS--water soluble antidotes for heavy metal poisoning. Annu Rev Pharmacol Toxicol 1983 1.76
3 Monomethylarsonous acid (MMA(III)) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem Res Toxicol 2001 1.72
4 Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily. Chem Res Toxicol 2001 1.65
5 Speciation of key arsenic metabolic intermediates in human urine. Anal Chem 2000 1.65
6 Pharmacokinetics of meso-2,3-dimercaptosuccinic acid in patients with lead poisoning and in healthy adults. J Pediatr 1994 1.58
7 Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine. Environ Health Perspect 2000 1.58
8 Choroid plexus protects cerebrospinal fluid against toxic metals. FASEB J 1991 1.27
9 Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. Chem Res Toxicol 1995 1.26
10 Rabbit muscle creatine phosphokinase. CDNA cloning, primary structure and detection of human homologues. J Biol Chem 1984 1.24
11 The enigma of arsenic carcinogenesis: role of metabolism. Toxicol Sci 1999 1.16
12 Neurobehavioral effects from exposure to dental amalgam Hg(o): new distinctions between recent exposure and Hg body burden. FASEB J 1998 1.10
13 N-(2,3-dimercaptopropyl)phthalamidic acid (DMPA) increases polonium-210 excretion. Biol Met 1990 1.07
14 DNA and gene therapy: uncoating of polyoma pseudovirus in mouse embryo cells. Proc Natl Acad Sci U S A 1970 1.04
15 A deoxyribonuclease found after infection of Bacillus subtilis with phage SP3. Proc Natl Acad Sci U S A 1965 1.04
16 Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase. Chem Res Toxicol 1999 1.04
17 Enzymatic methylation of arsenic compounds. III. The marmoset and tamarin, but not the rhesus, monkeys are deficient in methyltransferases that methylate inorganic arsenic. Toxicol Appl Pharmacol 1996 1.02
18 DNA and gene therapy: transfer of mouse DNA to human and mouse embryonic cells by polyoma pseudovirions. Proc Natl Acad Sci U S A 1971 1.02
19 Formation of nucleoprotein complexes between polyoma empty capsides and DNA. J Virol 1975 1.01
20 Determination and metabolism of dithiol chelating agents. XVI: Pharmacokinetics of 2,3-dimercapto-1-propanesulfonate after intravenous administration to human volunteers. J Pharmacol Exp Ther 1994 0.98
21 Determination and metabolism of dithiol chelating agents. XII. Metabolism and pharmacokinetics of sodium 2,3-dimercaptopropane-1-sulfonate in humans. J Pharmacol Exp Ther 1991 0.97
22 Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase. Chem Res Toxicol 2000 0.97
23 Central nervous system toxicity of manganese. I. Inhibition of spontaneous motor activity in rats after intrathecal administration of manganese chloride. Fundam Appl Toxicol 1995 0.96
24 Structural basis of the antagonism between inorganic mercury and selenium in mammals. Chem Res Toxicol 2000 0.96
25 Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes. Toxicol Appl Pharmacol 1999 0.95
26 Central nervous system toxicity of manganese. II: Cocaine or reserpine inhibit manganese concentration in the rat brain. Neurotoxicology 1999 0.95
27 The deoxycytidylate deaminase found in Bacillus subtilis infected with phage SP8. Biochemistry 1967 0.95
28 Deoxythymidylate 5'-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C. J Biol Chem 1966 0.94
29 Polyoma pseudovirions. I. Sequence of events in primary mouse embryo cells leading to pseudovirus production. J Virol 1972 0.93
30 Arsenite methylation by methylvitamin B12 and glutathione does not require an enzyme. Toxicol Appl Pharmacol 1999 0.92
31 Determination and metabolism of dithiol chelating agents. XV. The meso-2,3-dimercaptosuccinic acid-cysteine (1:2) mixed disulfide, a major urinary metabolite of DMSA in the human, increases the urinary excretion of lead in the rat. J Pharmacol Exp Ther 1993 0.91
32 Arsenic binding proteins of mammalian systems: I. Isolation of three arsenite-binding proteins of rabbit liver. Toxicology 1994 0.91
33 Determination and metabolism of dithiol chelating agents: X. In humans, meso-2,3-dimercaptosuccinic acid is bound to plasma proteins via mixed disulfide formation. J Pharmacol Exp Ther 1990 0.91
34 Behavioral effects of low-level exposure to Hg0 among dental professionals: a cross-study evaluation of psychomotor effects. Neurotoxicol Teratol 1998 0.89
35 Fluorometric determination of 2,3-dimercaptopropane-1-sulfonic acid and other dithiols by precolumn derivatization with bromobimane and column liquid chromatography. J Chromatogr 1986 0.88
36 Determination and metabolism of dithiol chelating agents. VIII. Metal complexes of meso-dimercaptosuccinic acid. Toxicol Appl Pharmacol 1989 0.87
37 DMSA, DMPS, and DMPA--as arsenic antidotes. Fundam Appl Toxicol 1984 0.87
38 Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid. Biochem Biophys Res Commun 1980 0.86
39 Cell-free assembly of a polyoma-like particle from empty capsids and DNA. Virology 1979 0.86
40 Monomethylarsonic acid reductase and monomethylarsonous acid in hamster tissue. Chem Res Toxicol 2000 0.86
41 Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides. J Pharmacol Exp Ther 1996 0.85
42 Determination and metabolism of dithiol chelating agents. VII. Biliary excretion of dithiols and their interactions with cadmium and metallothionein. Fundam Appl Toxicol 1990 0.85
43 The use of DNA for gene therapy--the need, experimental approach, and implications. Perspect Biol Med 1970 0.83
44 Sodium 2,3-dimercaptopropane-1-sulfonate challenge test for mercury in humans. III. Urinary mercury after exposure to mercurous chloride. J Pharmacol Exp Ther 1996 0.83
45 Enzymatic methylation of arsenic compounds. VI. Characterization of hamster liver arsenite and methylarsonic acid methyltransferase activities in vitro. Toxicol Appl Pharmacol 1998 0.83
46 Polyoma pseudovirions. II. Influence of host cell on pseudovirus production. J Virol 1973 0.83
47 DMPS (2,3-dimercaptopropane-1-sulfonate, dimaval) decreases the body burden of mercury in humans exposed to mercurous chloride. J Pharmacol Exp Ther 1998 0.83
48 Enzymatic methylation of arsenic compounds: IV. In vitro and in vivo deficiency of the methylation of arsenite and monomethylarsonic acid in the guinea pig. Mutat Res 1997 0.83
49 Diversity of inorganic arsenite biotransformation. Biol Trace Elem Res 1999 0.83
50 Determination and metabolism of dithiol-chelating agents: electrolytic and chemical reduction of oxidized dithiols in urine. Anal Biochem 1987 0.82
51 Protection of mice against lethal effects of sodium arsenite--a quantitative comparison of a number of chelating agents. Toxicol Appl Pharmacol 1981 0.81
52 Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid. Adv Enzyme Regul 1982 0.81
53 Determination and metabolism of dithiol chelating agents. VI. Isolation and identification of the mixed disulfides of meso-2,3-dimercaptosuccinic acid with L-cysteine in human urine. Toxicol Appl Pharmacol 1989 0.81
54 Polyoma-like particle: characterization of the DNA encapsidated in vitro by polyoma empty capsids. J Biol Chem 1982 0.81
55 Evaluation of Drosophila melanogaster as an alternative animal for studying the neurotoxicity of heavy metals. Biometals 1992 0.80
56 The synthesis and breakdown of nucleic acids in mammalian cells transformed by oncogenic viruses. I. Purification and properties of an endonuclease from baby hamster kidney cells transformed by polyoma virus. J Biol Chem 1970 0.80
57 Sodium 2,3-dimercapto-1-propanesulfonate (DMPS) treatment does not redistribute lead or mercury to the brain of rat. Toxicology 1996 0.79
58 The polyoma pseudovirion--its properties, production, and use in transferring DNA to mouse and human cells. Johns Hopkins Med J Suppl 1973 0.79
59 Sequential cleavage of dinucleotides from DNA by phage Sp3 DNAse. Proc Natl Acad Sci U S A 1968 0.79
60 BAL increases the arsenic-74 content of rabbit brain. Toxicol Appl Pharmacol 1983 0.78
61 Degradation of pseudoviral DNA after infection of mouse cells with polyoma pseudovirions. Proc Natl Acad Sci U S A 1974 0.78
62 Anti-lewisite activity and stability of meso-dimercaptosuccinic acid and 2,3-dimercapto-1-propanesulfonic acid. Life Sci 1982 0.78
63 Determination and metabolism of dithiol chelating agents. IV. Urinary excretion of meso-2,3-dimercaptosuccinic acid and mercaptosuccinic acid in rabbits given meso-2,3-dimercaptosuccinic acid. Biochem Pharmacol 1989 0.77
64 N-(2,3-dimercaptopropyl)phthalamidic acid: protection, in vivo and in vitro, against arsenic intoxication. Toxicol Appl Pharmacol 1984 0.77
65 Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidney. Toxicology 1997 0.77
66 Gene therapy systems: the need, experimental approach, and implications. Ann N Y Acad Sci 1971 0.76
67 Penicillamine and analogous chelating agents. Ann N Y Acad Sci 1971 0.76
68 Synthesis and properties of the monomethyl ester of meso-dimercaptosuccinic acid and its chelates of lead (II), cadmium(II), and mercury(II). Chem Res Toxicol 1991 0.76
69 Lead chelates of meso- and racemic-dimercaptosuccinic acid. J Inorg Biochem 1989 0.76
70 Experimental gene delivery systems for mammalian cells-the polyoma pseudovirus system. Adv Enzyme Regul 1978 0.75
71 DL- and meso-dimercaptosuccinic acid: in vitro and in vivo studies with sodium arsenite. Toxicol Appl Pharmacol 1983 0.75
72 Dimercaptan metal-binding agents influence the biotransformation of arsenite in the rabbit. Toxicol Appl Pharmacol 1985 0.75
73 Polyoma pseudovirions: an experimental model for the development of DNA for gene therapy. Fed Proc 1972 0.75
74 Water soluble dithiol metal binding agents--efficacies and biotransformation. Acta Pharmacol Toxicol (Copenh) 1986 0.75
75 Optical isomers of 2,3-dimercapto-1-propanesulfonate: antidotal activity, in vitro and in vivo, against sodium arsenite. J Pharmacol Exp Ther 1983 0.75
76 The dimethyl ester of meso-2,3-dimercaptosuccinic acid and its interactions with Cd2+ and rabbit liver metallothionein I. Chem Res Toxicol 1992 0.75
77 Determination and metabolism of dithiol chelating agents. III. Formation of oxidized metabolites of 2,3-dimercaptopropane-1-sulfonic acid in rabbit. Drug Metab Dispos 1988 0.75
78 Sequential cleavage of dinucleotides from DNA by SP3 DNase. 3. Substrate specificity and initiation of the hydrolysis from the 5-terminus of polynucleotides. J Mol Biol 1970 0.75
79 Gene transfer by polyoma-like particles assembled in a cell-free system. Science 1983 0.75
80 Assembly of a polyoma-like particle from empty capsids and DNA in a cell-free system. Adv Enzyme Regul 1980 0.75