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1
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Differences in stereoselectivity and catalytic efficiency of three human glutathione transferases in the conjugation of glutathione with 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
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Cancer Res
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1986
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1.20
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2
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Differences in detection of DNA adducts in the 32P-postlabelling assay after either 1-butanol extraction or nuclease P1 treatment.
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Cancer Lett
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1989
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1.02
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3
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Differences in the occurrence of glutathione transferase isoenzymes in rat lung and liver.
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Biochem Biophys Res Commun
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1985
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0.91
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4
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Glutathione transferases in rat lung: the presence of transferase 7-7, highly efficient in the conjugation of glutathione with the carcinogenic (+)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
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Carcinogenesis
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1986
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0.91
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5
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Activation of some aromatic amines to mutagenic products by prostaglandin endoperoxide synthetase.
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Cancer Res
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1983
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0.86
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6
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Evaluation of potential health effects of 10 kHz magnetic fields: a rodent reproductive study.
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Bioelectromagnetics
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1998
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0.84
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7
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The enzymatic conjugation of glutathione with bay-region diol-epoxides of benzo[a]pyrene, benz[a]anthracene and chrysene.
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Carcinogenesis
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1986
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0.83
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8
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The relationship between increases in the hepatic content of cytochrome P-450, form 5, and in the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbital.
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Mol Pharmacol
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1983
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0.83
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9
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Inter-species variation in the metabolism and inhibition of N-[(2'-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidase.
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Biochem Pharmacol
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2000
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0.82
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10
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Selective activation of some dihydrodiols of several polycyclic aromatic hydrocarbons to mutagenic products by prostaglandin synthetase.
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Cancer Res
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1982
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0.82
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11
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A rapid and simple scheme for confirmation of Salmonella tester strain phenotype.
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Environ Mutagen
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1981
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0.81
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12
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Fetal phenytoin exposure, hypoplastic nails, and jitteriness.
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Arch Dis Child
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1991
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0.81
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13
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Oxidative metabolism of amsacrine by the neutrophil enzyme myeloperoxidase.
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Biochem Pharmacol
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1992
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0.81
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14
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Metabolism of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in cancer patients undergoing a phase I clinical trial.
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Cancer Chemother Pharmacol
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1999
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0.80
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15
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Intraperitoneal administration of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in the mouse: bioavailability, pharmacokinetics and toxicity after a single dose.
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Cancer Chemother Pharmacol
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1992
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0.79
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16
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Pharmacokinetics of acridine-4-carboxamide in the rat, with extrapolation to humans.
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Cancer Chemother Pharmacol
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1993
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0.79
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17
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Pharmacokinetics and toxicity of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide after i.v. administration in the mouse.
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Cancer Chemother Pharmacol
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1992
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0.79
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18
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Giant cell arteritis of the female genital tract.
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Br J Obstet Gynaecol
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1979
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0.78
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19
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Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1.
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Carcinogenesis
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1983
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0.78
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20
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Tumour profile of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide after intraperitoneal administration in the mouse.
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Cancer Chemother Pharmacol
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1993
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0.78
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21
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Cranial nerve agenesis in a fetus exposed to carbamazepine.
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Dev Med Child Neurol
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1983
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0.78
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22
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Plasma protein binding of the experimental antitumour agent acridine-4-carboxamide in man, dog, rat and rabbit.
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J Pharm Pharmacol
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1994
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0.77
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23
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Disposition of amsacrine and its analogue 9-([2-methoxy-4-[(methylsulfonyl)amino]phenyl]amino)-N,5-dimethyl-4- acridinecarboxamide (CI-921) in plasma, liver, and Lewis lung tumors in mice.
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Cancer Res
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1990
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0.77
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24
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A comparison of the requirements for antitumour activity and antibacteriophage lambda activity for a series of non-intercalative DNA-binding agents.
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Eur J Cancer Clin Oncol
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1982
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0.76
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25
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Thiolytic cleavage and binding of the antitumour agent CI-921 in blood.
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Drug Metabol Drug Interact
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1988
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0.75
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26
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Age-related changes in mutagen activation by rat tissues.
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Chem Biol Interact
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1982
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0.75
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27
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Inhibition of T4 bacteriophage yield by 9-anilinoacridines; comparison with in vivo antitumour activity.
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Eur J Cancer
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1980
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0.75
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28
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Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2'-(dimethylamino)ethyl]acridine-4-carboxamide.
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Xenobiotica
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1993
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0.75
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29
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Interactions between xenobiotics that increase or decrease the levels of cytochrome P-450 isozymes in rabbit lung and liver.
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J Biol Chem
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1983
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0.75
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30
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Acute hepatic encephalopathy with acute pancreatitis in pregnancy.
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J Obstet Gynaecol
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2006
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0.75
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31
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The importance of 2-aminofluorene in the mutagenic activation of 2-acetylaminofluorene.
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Mutat Res
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1986
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0.75
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32
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Prescribing in pregnancy. Epilepsy in pregnancy.
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Clin Obstet Gynaecol
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1986
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0.75
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