J E Barker

Author PubWeight™ 83.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 2000 5.78
2 Treatment of murine mucopolysaccharidosis type VII by syngeneic bone marrow transplantation in neonates. Lab Invest 1993 1.81
3 Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes. Cell 1984 1.77
4 Novel inheritance of the murine severe combined anemia and thrombocytopenia (Scat) phenotype. Cell 1993 1.72
5 Development of the mouse hematopoietic system. I. Types of hemoglobin produced in embryonic yolk sac and liver. Dev Biol 1968 1.72
6 Percutaneous intravenous injection in neonatal mice. Lab Anim Sci 1999 1.65
7 Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation. Blood 1991 1.61
8 Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice. Proc Natl Acad Sci U S A 2000 1.57
9 Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer. Nature 1993 1.55
10 Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice. Arterioscler Thromb Vasc Biol 2001 1.40
11 Red cell membranes of ankyrin-deficient nb/nb mice lack band 3 tetramers but contain normal membrane skeletons. Biochemistry 1997 1.37
12 Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. J Cell Biol 1991 1.32
13 Enzyme replacement in murine mucopolysaccharidosis type VII: neuronal and glial response to beta-glucuronidase requires early initiation of enzyme replacement therapy. Pediatr Res 1999 1.31
14 Small, membrane-bound, alternatively spliced forms of ankyrin 1 associated with the sarcoplasmic reticulum of mammalian skeletal muscle. J Cell Biol 1997 1.27
15 Ankyrin and the hemolytic anemia mutation, nb, map to mouse chromosome 8: presence of the nb allele is associated with a truncated erythrocyte ankyrin. Proc Natl Acad Sci U S A 1990 1.26
16 Hemopoietic stem cells in murine embryonic yolk sac and peripheral blood. Proc Natl Acad Sci U S A 1989 1.23
17 Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione. Free Radic Biol Med 1996 1.14
18 Hemoglobin switching in sheep and goats. Preparation and characterization of complementary DNAs specific for the alpha-, beta-, and gamma-globin messenger RNAs of sheep. J Biol Chem 1977 1.11
19 Brain spectrin: of mice and men. Brain Res Bull 1995 1.09
20 Complex patterns of sequence variation and multiple 5' and 3' ends are found among transcripts of the erythroid ankyrin gene. J Biol Chem 1993 1.07
21 Na,K-ATPase in skeletal muscle: two populations of beta-spectrin control localization in the sarcolemma but not partitioning between the sarcolemma and the transverse tubules. J Cell Sci 2001 1.06
22 Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin. Proc Natl Acad Sci U S A 1985 1.06
23 An alternative first exon in the distal end of the erythroid ankyrin gene leads to production of a small isoform containing an NH2-terminal membrane anchor. Genomics 1998 1.04
24 Downeast anemia (dea), a new mouse model of severe nonspherocytic hemolytic anemia caused by hexokinase (HK(1)) deficiency. Blood Cells Mol Dis 2002 1.02
25 Nonablative neonatal marrow transplantation attenuates functional and physical defects of beta-glucuronidase deficiency. Blood 2001 0.98
26 Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis. Blood 1997 0.95
27 Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo. Proc Natl Acad Sci U S A 1992 0.95
28 Increased cation permeability in mutant mouse red blood cells with defective membrane skeletons. Blood 1995 0.94
29 Fetal compensation of the hemolytic anemia in mice homozygous for the normoblastosis (nb) mutation. Blood 1992 0.93
30 Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation. Bone 2000 0.92
31 Murine recessive hereditary spherocytosis, sph/sph, is caused by a mutation in the erythroid alpha-spectrin gene. Hematol J 2000 0.91
32 Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. Am J Physiol 1995 0.91
33 Development of the mouse hematopoietic system. II. Estimation of spleen and liver "stem" cell number. J Cell Physiol 1969 0.91
34 Genetic modifiers of polycystic kidney disease in intersubspecific KAT2J mutants. Genomics 1999 0.89
35 Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival. Br J Pharmacol 2001 0.89
36 Nitric oxide synthase II gene disruption: implications for tumor growth and vascular endothelial growth factor production. Cancer Res 2001 0.89
37 Chromosomal location of three spectrin genes: relationship to the inherited hemolytic anemias of mouse and man. Proc Natl Acad Sci U S A 1988 0.88
38 The treatment of paediatric infections with the lincomycins. Br J Clin Pract 1973 0.88
39 Heritable severe combined anemia and thrombocytopenia in the mouse: description of the disease and successful therapy. Blood 1990 0.88
40 Nitric oxide, energy metabolism and neurological disease. Biochem Soc Trans 1997 0.87
41 The role of mast cells in ischaemia-reperfusion injury in murine skeletal muscle. J Pathol 2000 0.87
42 Hemoglobin switching in sheep and goats. V. Effect of erythropoietin concentration on in vitro erythroid colony growth and globin synthesis. J Cell Biol 1975 0.86
43 Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice. Blood 1993 0.86
44 Hemogloblin switching in sheep and goats: erythropoietin-dependent synthesis of hemoglobin C in goat bone-marrow cultures. Proc Natl Acad Sci U S A 1973 0.86
45 Murine erythrocyte ankyrin cDNA: highly conserved regions of the regulatory domain. Mamm Genome 1992 0.86
46 Enzyme replacement therapy improves reproductive performance in mucopolysaccharidosis type VII mice but does not prevent postnatal losses. Pediatr Res 1999 0.85
47 Hertwig's anemia: characterization of the stem cell defect. Blood 1983 0.85
48 Hemoglobin switching in sheep: commitment of erythroid stem cells to expression of the betaC-globin gene and accumulation of betaC-globin mRNA. Cell 1978 0.85
49 The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences. Brain Res Mol Brain Res 1993 0.85
50 Reduced incidence of thrombosis in mice with hereditary spherocytosis following neonatal treatment with normal hematopoietic cells. Blood 2001 0.85
51 Brain alpha erythroid spectrin: identification, compartmentalization, and beta spectrin associations. Brain Res 1994 0.83
52 The flaky skin (fsn) mutation in mice: map location and description of the anemia. Blood 1995 0.83
53 A field study of the survival of Legionella pneumophila in a hospital hot-water system. Epidemiol Infect 1990 0.82
54 Hematopoietic cells from -spectrin-deficient mice are sufficient to induce thrombotic events in hematopoietically ablated recipients. Blood 1998 0.82
55 Complete nucleotide sequence of the murine erythroid beta-spectrin cDNA and tissue-specific expression in normal and jaundiced mice. Blood 1993 0.81
56 A genetically myeloablated MPS VII model detects the expansion and curative properties of as few as 100 enriched murine stem cells. Exp Hematol 1999 0.81
57 Mouse models of genetic diseases. Birth Defects Orig Artic Ser 1987 0.81
58 Gene therapy for murine mucopolysaccharidosis type VII. Neuromuscul Disord 1997 0.81
59 Hemoglobin switching in sheep and goats. VI. Commitment of erythroid colony-forming cells to the synthesis of betaC globin. J Cell Biol 1976 0.81
60 Hemoglobin switching in sheep: a comparison of the erythropoietin-induced switch to HbC and the fetal to adult hemoglobin switch. Blood 1980 0.81
61 The competitive ability of stem cells from mice with Hertwig's anemia. J Cell Physiol 1982 0.81
62 Defective spectrin integrity and neonatal thrombosis in the first mouse model for severe hereditary elliptocytosis. Blood 2001 0.80
63 Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11. Mamm Genome 1992 0.80
64 Electrocardiographic and other cardiac anomalies in beta-glucuronidase-null mice corrected by nonablative neonatal marrow transplantation. Proc Natl Acad Sci U S A 2004 0.80
65 Hemoglobin switching in sheep and goats: induction of hemoglobin C synthesis in cultures of sheep fetal erythroid cells. Proc Natl Acad Sci U S A 1977 0.80
66 Embryonic mouse peripheral blood colony-forming units. Nature 1970 0.80
67 The hematopoietic stem cells of alpha-thalassemic mice. Blood 1985 0.80
68 Changes in Clara cell 10 kDa protein (CC10)-positive cell distribution in acute lung injury following repeated lipopolysaccharide challenge in the rat. Toxicol Pathol 2008 0.79
69 Mapping of the murine and rat Facc genes and assessment of flexed-tail as a candidate mouse homolog of Fanconi anemia group C. Mamm Genome 1993 0.78
70 Overview: mechanisms of the regulation of hemoglobin synthesis at the cellular level. Ann N Y Acad Sci 1980 0.78
71 Chromosome abnormalities in mice with Hertwig's anemia. Blood 1984 0.78
72 Deleterious effects of irradiation and bone marrow transplantation therapy in the genetically anemic an/an mouse. Blood 1989 0.78
73 Decreased endothelial cell glutathione and increased sensitivity to oxidative stress in an in vitro blood-brain barrier model system. Brain Res 1998 0.78
74 Gene transfer to ankyrin-deficient bone marrow corrects spherocytosis in vitro. Exp Hematol 2000 0.77
75 Erythroid phosphatidyl serine exposure is not predictive of thrombotic risk in mice with hemolytic anemia. Blood Cells Mol Dis 2000 0.77
76 Percutaneous intravenous injection in neonatal mice. Comp Med 2000 0.77
77 Structure-based design of novel, urea-containing FKBP12 inhibitors. J Med Chem 1996 0.77
78 The murine mutation jaundiced is caused by replacement of an arginine with a stop codon in the mRNA encoding the ninth repeat of beta-spectrin. Proc Natl Acad Sci U S A 1994 0.77
79 Hemoglobin switching in sheep and goats: aspects of the molecular mechanism. Ann N Y Acad Sci 1974 0.76
80 Hemoglobin switching in sheep: characteristics of BFU-E-derived colonies from fetal liver. Blood 1980 0.76
81 A method to enrich mouse hematopoietic stem cells. Blood 1983 0.75
82 Activation and inactivation of genes determining hemoglobin types.20s. J Cell Physiol 1975 0.75
83 Mouse globin gene nomenclature. J Hered 1988 0.75