Published in JAMA on June 09, 1999
Phase I Trial of Smallpox Vaccine | NCT00046397
Phase I/II Trial of Modified Vaccinia Virus Ankara (MVA) Vaccine Against Smallpox | NCT00053742
Public health assessment of potential biological terrorism agents. Emerg Infect Dis (2002) 8.49
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Modeling potential responses to smallpox as a bioterrorist weapon. Emerg Infect Dis (2001) 3.39
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Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox. Proc Natl Acad Sci U S A (2004) 2.36
Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. J Virol (2005) 2.18
Modified vaccinia virus Ankara protects macaques against respiratory challenge with monkeypox virus. J Virol (2005) 2.11
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Ring vaccination and smallpox control. Emerg Infect Dis (2004) 1.88
The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. Proc Natl Acad Sci U S A (2004) 1.85
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. J Virol (2008) 1.77
Smallpox and pan-orthopox virus detection by real-time 3'-minor groove binder TaqMan assays on the roche LightCycler and the Cepheid smart Cycler platforms. J Clin Microbiol (2004) 1.77
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Detection of smallpox virus DNA by LightCycler PCR. J Clin Microbiol (2002) 1.62
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Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246. Antimicrob Agents Chemother (2009) 1.52
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The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies. Proc Natl Acad Sci U S A (2005) 1.24
Risks of serious complications and death from smallpox vaccination: a systematic review of the United States experience, 1963-1968. BMC Public Health (2003) 1.24
Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor. Antimicrob Agents Chemother (2008) 1.24
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A Canadian national survey of attitudes and knowledge regarding preventive vaccines. J Immune Based Ther Vaccines (2003) 1.11
A simulation analysis to characterize the dynamics of vaccinating behaviour on contact networks. BMC Infect Dis (2009) 1.10
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Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol (2008) 1.06
Smallpox vaccine: the good, the bad, and the ugly. Clin Med Res (2003) 1.05
Endemic, notifiable bioterrorism-related diseases, United States, 1992-1999. Emerg Infect Dis (2003) 1.05
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Inactivation of poxviruses by upper-room UVC light in a simulated hospital room environment. PLoS One (2008) 1.04
Statistical approach to estimate vaccinia-specific neutralizing antibody titers using a high-throughput assay. Clin Vaccine Immunol (2009) 1.04
Logistics of community smallpox control through contact tracing and ring vaccination: a stochastic network model. BMC Public Health (2004) 1.03
Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice. Proc Natl Acad Sci U S A (2009) 1.03
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model. Antivir Ther (2010) 1.02
Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase. Nucleic Acids Res (2003) 1.01
Protection against vaccinia virus challenge by CD8 memory T cells resolved by molecular mimicry. J Virol (2006) 1.01
Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein. Virology (2007) 1.00
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Vaccinia viruses: vaccines against smallpox and vectors against infectious diseases and tumors. Expert Rev Vaccines (2011) 0.98
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Transcriptomic profiles of high and low antibody responders to smallpox vaccine. Genes Immun (2013) 0.94
Characterization of UVC light sensitivity of vaccinia virus. Appl Environ Microbiol (2007) 0.93
CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol (2012) 0.93
Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001. J Infect Dis (2012) 0.93
Diverse recognition of conserved orthopoxvirus CD8+ T cell epitopes in vaccinated rhesus macaques. Vaccine (2009) 0.92
Rapid and high-throughput pan-Orthopoxvirus detection and identification using PCR and mass spectrometry. PLoS One (2009) 0.92
Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein. J Virol (2014) 0.89
Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation. Virology (2006) 0.88
Extracting key information from historical data to quantify the transmission dynamics of smallpox. Theor Biol Med Model (2008) 0.88
Role for CCR5 in dissemination of vaccinia virus in vivo. J Virol (2008) 0.88
Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization. Virol J (2009) 0.87
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5-(Dimethoxymethyl)-2'-deoxyuridine: a novel gem diether nucleoside with anti-orthopoxvirus activity. J Med Chem (2006) 0.87
Aerosolized cidofovir is retained in the respiratory tract and protects mice against intranasal cowpox virus challenge. Antimicrob Agents Chemother (2003) 0.87
Progression of pathogenic events in cynomolgus macaques infected with variola virus. PLoS One (2011) 0.87
Risks and benefits of preexposure and postexposure smallpox vaccination. Emerg Infect Dis (2003) 0.86
Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans. Hum Immunol (2008) 0.86
A novel high-throughput vaccinia virus neutralization assay and preexisting immunity in populations from different geographic regions in China. PLoS One (2012) 0.86
Smallpox during pregnancy and maternal outcomes. Emerg Infect Dis (2006) 0.85
Persisting humoral antiviral immunity within the Japanese population after the discontinuation in 1976 of routine smallpox vaccinations. Clin Diagn Lab Immunol (2005) 0.85
The heterogeneity of human antibody responses to vaccinia virus revealed through use of focused protein arrays. Vaccine (2009) 0.85
Emerging illness and bioterrorism: implications for public health. J Urban Health (2001) 0.85
Coadministration of cidofovir and smallpox vaccine reduced vaccination side effects but interfered with vaccine-elicited immune responses and immunity to monkeypox. J Virol (2008) 0.84
Smallpox and biological warfare: a disease revisited. Proc (Bayl Univ Med Cent) (2005) 0.84
Should the US and Russia destroy their stocks of smallpox virus? BMJ (2007) 0.84
Uncertain benefit: the public policy of approving smallpox vaccine research. Am J Public Health (2004) 0.83
Traditional smallpox vaccination with reduced risk of inadvertent contact spread by administration of povidone iodine ointment. Vaccine (2007) 0.83
The structure of G4, the poxvirus disulfide oxidoreductase essential for virus maturation and infectivity. J Virol (2006) 0.83
Synthesis and early development of hexadecyloxypropylcidofovir: an oral antipoxvirus nucleoside phosphonate. Viruses (2010) 0.83
Development of the small-molecule antiviral ST-246 as a smallpox therapeutic. Future Virol (2011) 0.82
CD4+ T cells provide intermolecular help to generate robust antibody responses in vaccinia virus-vaccinated humans. J Immunol (2013) 0.82
Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. J Virol (2012) 0.82
Educating health professionals to respond to bioterrorism. Public Health Rep (2005) 0.81
The identification of HLA class II-restricted T cell epitopes to vaccinia virus membrane proteins. Virology (2010) 0.81
Contacting passengers after exposure to measles on an international flight: Implications for responding to new disease threats and bioterrorism. Public Health Rep (2004) 0.81
Use of internally controlled real-time genome amplification for detection of variola virus and other orthopoxviruses infecting humans. J Clin Microbiol (2006) 0.81
Real-time PCR assay for detection of a new simulant for poxvirus biothreat agents. Appl Environ Microbiol (2009) 0.81
Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers. Antimicrob Agents Chemother (2012) 0.81
In vitro inhibition of monkeypox virus production and spread by Interferon-β. Virol J (2012) 0.81
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Tularemia as a biological weapon: medical and public health management. JAMA (2001) 13.23
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Botulinum toxin as a biological weapon: medical and public health management. JAMA (2001) 9.18
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Plague as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA (2000) 8.45
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