T B Kornberg

Author PubWeight™ 68.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions. Cell 1990 7.99
2 Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 1997 4.43
3 Expression of engrailed proteins in arthropods, annelids, and chordates. Cell 1989 3.98
4 Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 1999 3.45
5 Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 1994 2.94
6 Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 1997 2.72
7 Isolation of the proto-oncogene c-myb from D. melanogaster. Cell 1985 2.57
8 Isolation of cDNAs encoding the Drosophila GAGA transcription factor. Mol Cell Biol 1993 2.20
9 The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev 1992 2.18
10 Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter. Genes Dev 1990 2.05
11 Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 2000 1.83
12 GFP-tagged balancer chromosomes for Drosophila melanogaster. Mech Dev 2000 1.83
13 Expression of engrailed during segmentation in grasshopper and crayfish. Development 1989 1.78
14 Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. Development 1995 1.59
15 Small nuclear RNA transcription and ribonucleoprotein assembly in early Xenopus development. J Cell Biol 1983 1.46
16 GFP-tagged balancer chromosomes for Drosophila melanogaster. Mech Dev 1999 1.46
17 Repression of ci-D in posterior compartments of Drosophila by engrailed. Genes Dev 1990 1.42
18 Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila. Nature 1983 1.38
19 Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development. J Biol Chem 2000 1.29
20 Analysis of cubitus interruptus regulation in Drosophila embryos and imaginal disks. Development 1995 1.25
21 Ci: a complex transducer of the hedgehog signal. Trends Genet 1999 1.25
22 Reduction of transcription by homologue asynapsis in Drosophila imaginal discs. Nature 1996 1.25
23 Phosphorylation of the fused protein kinase in response to signaling from hedgehog. Proc Natl Acad Sci U S A 1996 1.23
24 Signaling reaches to new dimensions in Drosophila imaginal discs. Cell 2000 1.21
25 The Drosophila engrailed and invected genes: partners in regulation, expression and function. Genetics 1996 1.18
26 Blistered: a gene required for vein/intervein formation in wings of Drosophila. Development 1994 1.14
27 Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins. Nucleic Acids Res 2000 1.09
28 The Drosophila engrailed protein is phosphorylated by a serine-specific protein kinase. Nucleic Acids Res 1988 1.03
29 On the range of hedgehog signaling. Curr Opin Genet Dev 2000 0.97
30 Phosphorylation of the Drosophila engrailed protein at a site outside its homeodomain enhances DNA binding. J Biol Chem 1995 0.97
31 fushi tarazu protein expression in the cellular blastoderm of Drosophila detected using a novel imaging technique. Development 1989 0.97
32 Allele-specific quantification of Drosophila engrailed and invected transcripts. Proc Natl Acad Sci U S A 1994 0.96
33 Modifying expression of the engrailed gene of Drosophila melanogaster. Development 1988 0.92
34 polyhomeotic appears to be a target of engrailed regulation in Drosophila. Development 1995 0.89
35 Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster. Mech Dev 1995 0.87
36 Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc. Mol Cell 2000 0.87
37 Development of the D. melanogaster caudal segments involves suppression of the ventral regions of A8, A9 and A10. Development 1992 0.82
38 Analysis of the genes involved in organizing the tail segments of the Drosophila melanogaster embryo. Mech Dev 1995 0.80
39 Selection and characterization of sequences with high affinity for the engrailed protein of Drosophila. Mech Dev 1995 0.78
40 Proto-oncogenes of Drosophila melanogaster. Cold Spring Harb Symp Quant Biol 1985 0.77
41 DR-78, a novel Drosophila melanogaster genomic DNA fragment highly homologous to the DNA-binding domain of thyroid hormone-retinoic acid-vitamin D receptor subfamily. Biochim Biophys Acta 1993 0.75