Published in Prog Neurobiol on July 01, 1999
Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice. J Clin Invest (2009) 1.90
Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. J Neurosci (2014) 1.28
Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors. J Med Chem (2006) 1.16
Induced association of mu opioid (MOP) and type 2 cholecystokinin (CCK2) receptors by novel bivalent ligands. J Med Chem (2009) 1.06
Cholecystokinin receptor subtypes: role in the modulation of anxiety-related and reward-related behaviours in animal models. J Psychiatry Neurosci (2003) 1.02
Bidirectional modulation of GABAergic transmission by cholecystokinin in hippocampal dentate gyrus granule cells of juvenile rats. J Physiol (2006) 0.99
Structural basis of cholecystokinin receptor binding and regulation. Pharmacol Ther (2008) 0.95
Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells. J Neurosci (2011) 0.95
Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors. J Med Chem (2007) 0.94
Radiolabelled peptides for oncological diagnosis. Eur J Nucl Med Mol Imaging (2012) 0.93
Cholecystokinin facilitates neuronal excitability in the entorhinal cortex via activation of TRPC-like channels. J Neurophysiol (2011) 0.93
Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors. Amino Acids (2010) 0.90
Sensitivity of cholecystokinin receptors to membrane cholesterol content. Front Endocrinol (Lausanne) (2012) 0.87
N-methyl-D-aspartate receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce mu-opioid receptor internalization in the rat spinal cord. Neuroscience (2005) 0.85
Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ. Nat Neurosci (2016) 0.83
Effect of intranasally administered cholecystokinin on encoding of controlled and automatic memory processes. Psychopharmacology (Berl) (2008) 0.83
Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors. Peptides (2008) 0.83
Synthesis and evaluation of cholecystokinin trimers: a multivalent approach to pancreatic cancer detection and treatment. Bioorg Med Chem Lett (2013) 0.81
Requirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior. Hippocampus (2011) 0.79
Candidate genes in ocular dominance plasticity. Front Neurosci (2012) 0.78
Expression and cell-specific localization of cholecystokinin receptors in rat lung. World J Gastroenterol (2003) 0.78
New CCK2 agonists confirming the heterogeneity of CCK2 receptors: characterisation of BBL454. Naunyn Schmiedebergs Arch Pharmacol (2004) 0.78
The role of Sonic Hedgehog as a regulator of gastric function and differentiation. Vitam Horm (2012) 0.77
Cholecystokinin: an excitatory modulator of mitral/tufted cells in the mouse olfactory bulb. PLoS One (2013) 0.77
Cholecystokinin octapeptide improves cardiac function by activating cholecystokinin octapeptide receptor in endotoxic shock rats. World J Gastroenterol (2005) 0.76
Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue. Oncotarget (2016) 0.75
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature (1996) 7.15
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science (1999) 4.31
First glimpses at structure-function relationships of the nucleocapsid protein of retroviruses. J Mol Biol (1995) 3.63
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med (2000) 2.62
Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding. Nature (2000) 2.57
Determination of the structure of the nucleocapsid protein NCp7 from the human immunodeficiency virus type 1 by 1H NMR. EMBO J (1992) 2.21
The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice. Nature (1980) 2.13
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. J Exp Med (2001) 2.07
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science (1996) 2.01
Basic amino acids flanking the zinc finger of Moloney murine leukemia virus nucleocapsid protein NCp10 are critical for virus infectivity. J Virol (1993) 1.91
First large scale chemical synthesis of the 72 amino acid HIV-1 nucleocapsid protein NCp7 in an active form. Biochem Biophys Res Commun (1991) 1.88
High-affinity enkephalin-degrading peptidase in brain is increased after morphine. Nature (1978) 1.87
DNA Bifunctional intercalators. 2. Fluorescence properties and DNA binding interaction of an ethidium homodimer and an acridine ethidium heterodimer. Biochemistry (1978) 1.86
Ethidium dimer: a new reagent for the fluorimetric determination of nucleic acids. Anal Biochem (1979) 1.81
Two rotameric forms of open ring 7-methylguanine are present in alkylated polynucleotides. Nucleic Acids Res (1984) 1.74
International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev (1999) 1.74
NCp7 activates HIV-1Lai RNA dimerization by converting a transient loop-loop complex into a stable dimer. J Biol Chem (1996) 1.73
Absence of opiate rewarding effects in mice lacking dopamine D2 receptors. Nature (1997) 1.72
NMR structure of the HIV-1 regulatory protein VPR. J Mol Biol (2003) 1.64
DNA bifunctional intercalators. I. Synthesis and conformational properties of an ethidium homodimer and of an acridine ethidium heterodimer. Biochemistry (1978) 1.51
Conformational behaviour of the active and inactive forms of the nucleocapsid NCp7 of HIV-1 studied by 1H NMR. J Mol Biol (1994) 1.49
Solid phase synthesis of the retroviral nucleocapsid protein NCp10 of Moloney murine leukaemia virus and related "zinc-fingers" in free SH forms. Influence of zinc chelation on structural and biochemical properties. Int J Pept Protein Res (1990) 1.48
Expression of neutral endopeptidase (enkephalinase) in heterologous COS-1 cells. Characterization of the recombinant enzyme and evidence for a glutamic acid residue at the active site. J Biol Chem (1988) 1.40
Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein. Biopolymers (1997) 1.39
Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study. Biochemistry (1999) 1.39
Human immunodeficiency virus type 1 nucleocapsid protein specifically stimulates Mg2+-dependent DNA integration in vitro. J Virol (1997) 1.37
Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor. J Neurosci (1998) 1.35
DNA intercalating compounds as potential antitumor agents. 2. Preparation and properties of 7H-pyridocarbazole dimers. J Med Chem (1980) 1.34
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord. Brain Res (1990) 1.33
Evidence of interactions between the nucleocapsid protein NCp7 and the reverse transcriptase of HIV-1. J Biol Chem (1999) 1.27
The gag precursor contains a specific HIV-1 protease cleavage site between the NC (P7) and P1 proteins. FEBS Lett (1993) 1.27
Involvement of HIV-I nucleocapsid protein in the recruitment of reverse transcriptase into nucleoprotein complexes formed in vitro. J Biol Chem (1998) 1.26
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release. Proc Natl Acad Sci U S A (1996) 1.26
Conformation of Met5-enkephalin determined by high field PMR spectroscopy. Nature (1976) 1.26
Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors. Biochem Biophys Res Commun (1983) 1.23
NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions. J Mol Biol (1999) 1.23
Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: an electron microscopy investigation. Biopolymers (1998) 1.22
High-throughput fluorogenic assay for determination of botulinum type B neurotoxin protease activity. Anal Biochem (2001) 1.21
D-Tyr--Ser-Gly--Phe--Leu--Thr, a highly preferential ligand for delta-opiate receptors. FEBS Lett (1980) 1.15
Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid delta and dopamine D1 receptor stimulation. Eur J Pharmacol (1992) 1.14
Structure of the complex between the HIV-1 nucleocapsid protein NCp7 and the single-stranded pentanucleotide d(ACGCC). J Mol Biol (1998) 1.14
The zinc fingers of HIV nucleocapsid protein NCp7 direct interactions with the viral regulatory protein Vpr. J Biol Chem (1997) 1.14
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors. Neuroscience (2005) 1.14
NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos. Nat Struct Biol (1994) 1.13
The annealing of tRNA3Lys to human immunodeficiency virus type 1 primer binding site is critically dependent on the NCp7 zinc fingers structure. J Biol Chem (1998) 1.11
Aminopeptidase A inhibitors as potential central antihypertensive agents. Proc Natl Acad Sci U S A (1999) 1.11
Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with delta-9-tetrahydrocannabinol. Br J Pharmacol (1998) 1.10
Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect. Eur J Neurosci (2001) 1.08
Identification of glutamic acid 646 as a zinc-coordinating residue in endopeptidase-24.11. J Biol Chem (1991) 1.08
A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity. FASEB J (1999) 1.07
Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. J Neurochem (1997) 1.07
Primary structure homologies between two zinc metallopeptidases, the neutral endopeptidase 24.11 ("enkephalinase") and thermolysin, through clustering analysis. Biochemistry (1988) 1.07
DNA tris-intercalation: first acridine trimer with DNA affinity in the range of DNA regulatory proteins. Kinetic studies. Biochemistry (1985) 1.07
Two short basic sequences surrounding the zinc finger of nucleocapsid protein NCp10 of Moloney murine leukemia virus are critical for RNA annealing activity. Nucleic Acids Res (1993) 1.06
Involvement of delta-opioid receptors in the effects induced by endogenous enkephalins on learned helplessness model. Eur J Pharmacol (1998) 1.06
Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells. J Biol Chem (1989) 1.05
A highly sensitive fluorometric assay for "enkephalinase," a neutral metalloendopeptidase that releases tyrosine-glycine-glycine from enkephalins. Anal Biochem (1984) 1.04
Investigation of zinc-binding affinities of Moloney murine leukemia virus nucleocapsid protein and its related zinc finger and modified peptides. Biopolymers (1991) 1.04
Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain. Proc Natl Acad Sci U S A (1986) 1.04
Geometry of the antitumor drug ditercalinium bisintercalated into d(CpGpCpG)2 by 1H NMR. Proc Natl Acad Sci U S A (1987) 1.03
The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli. J Mol Biol (1999) 1.03
Zinc binding to the HIV-1 nucleocapsid protein: a thermodynamic investigation by fluorescence spectroscopy. Biochemistry (1996) 1.03
Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11). J Biol Chem (1991) 1.02
In vitro evidence for the interaction of tRNA(3)(Lys) with U3 during the first strand transfer of HIV-1 reverse transcription. Nucleic Acids Res (2000) 1.02
Complete differentiation between enkephalinase and angiotensin-converting enzyme inhibition by retro-thiorphan. Proc Natl Acad Sci U S A (1983) 1.01
Measurement of the expected DNA lengthening caused by mono-and bisintercalating drugs using electron microscopy. Biopolymers (1978) 1.01
NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol. Comparison with the Vpr N-terminal (1-51) and C-terminal (52-96) domains. Eur J Biochem (2002) 1.01
Radioimmunoassay of methionine- and leucine-enkephalins in regions of rat brain and comparison with endorphins estimated by a radioreceptor assay. J Neurochem (1978) 1.01
A model of PSI dimerization: destabilization of the C278-G303 stem-loop by the nucleocapsid protein (NCp10) of MoMuLV. Biochemistry (1996) 1.01
Cooperative exosite-dependent cleavage of synaptobrevin by tetanus toxin light chain. J Biol Chem (1997) 1.00
Binding of the HIV-1 nucleocapsid protein to the primer tRNA(3Lys), in vitro, is essentially not specific. J Biol Chem (1995) 1.00
Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway. J Biol Chem (1998) 1.00
Enkephalin dipeptidyl carboxypeptidase (enkephalinase) activity: selective radioassay, properties, and regional distribution in human brain. J Neurochem (1982) 0.99
Synthesis of 11H-pyridocarbazoles and derivatives. Comparison of their DNA binding and antitumor activity with those of 6H- and 7H-pyridocarbazoles. J Med Chem (1986) 0.99
Effects of kelatorphan and other peptidase inhibitors on the in vitro and in vivo release of methionine-enkephalin-like material from the rat spinal cord. J Pharmacol Exp Ther (1986) 0.98
Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction. Br J Pharmacol (2001) 0.97
Solution structure of GAP SH3 domain by 1H NMR and spatial arrangement of essential Ras signaling-involved sequence. EMBO J (1994) 0.97
Centrally administered cholecystokinin suppresses feeding through a peripheral-type receptor mechanism. J Pharmacol Exp Ther (1991) 0.96
Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr. FEBS Lett (1997) 0.96
Characterization of neutral endopeptidase in vascular cells, modulation of vasoactive peptide levels. Eur J Pharmacol (1998) 0.96
Induction of an abortive and futile DNA repair process in E. coli by the antitumor DNA bifunctional intercalator, ditercalinium: role in polA in death induction. Nucleic Acids Res (1988) 0.96
Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action. Biochemistry (1998) 0.96
Heteronuclear NMR studies of the interaction of tRNA(Lys)3 with HIV-1 nucleocapsid protein. J Mol Biol (2001) 0.96
Preferential conformation of the endogenous opiate-like pentapeptide Met-enkephalin in DMSO-D6 solution determined by high field H NMR. Biochem Biophys Res Commun (1976) 0.95
NMR structure of the (1-51) N-terminal domain of the HIV-1 regulatory protein Vpr. Eur J Biochem (1999) 0.95
The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia. Eur J Pharmacol (1984) 0.94
New kelatorphan-related inhibitors of enkephalin metabolism: improved antinociceptive properties. J Med Chem (1989) 0.94
Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats. J Pharmacol Exp Ther (1992) 0.94
Structural requirements for specific recognition of mu or delta opiate receptors. Mol Pharmacol (1981) 0.94
Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein R. J Virol (2000) 0.93
Chronic morphine administration causes region-specific increase of brain type VIII adenylyl cyclase mRNA. Eur J Pharmacol (1994) 0.93
Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [35S]GTPgammaS binding assays. Eur J Pharmacol (1999) 0.92
The use of a monoclonal antibody for the rapid purification of kidney neutral endopeptidase ("enkephalinase") solubilized in octyl glucoside. Biochem Cell Biol (1987) 0.92
A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity. Proc Natl Acad Sci U S A (1999) 0.92