Effects of (-)-tertatolol, (-)-penbutolol and (+/-)-pindolol in combination with paroxetine on presynaptic 5-HT function: an in vivo microdialysis and electrophysiological study.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 1566011)

Published in Br J Pharmacol on May 01, 1999

Authors

S E Gartside1, E M Clifford, P J Cowen, T Sharp

Author Affiliations

1: Oxford University Department of Clinical Pharmacology, Radcliffe Infirmary.

Articles cited by this

Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry (1990) 3.57

Current advances and trends in the treatment of depression. Trends Pharmacol Sci (1994) 3.49

Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet (1997) 3.12

Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors. Arch Gen Psychiatry (1994) 2.54

Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists. Trends Neurosci (1996) 2.22

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635. Eur J Pharmacol (1995) 1.64

Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression. J Clin Psychopharmacol (1995) 1.63

Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial. Am J Psychiatry (1997) 1.59

Pindolol augmentation of antidepressant therapy. Br J Psychiatry (1998) 1.59

Direct evidence for an interaction of beta-adrenergic blockers with the 5-HT receptor. Nature (1977) 1.38

The serotoninergic innervation of cerebral cortex: different classes of axon terminals arise from dorsal and median raphe nuclei. Synapse (1987) 1.31

Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT. Br J Pharmacol (1995) 1.26

Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain. Naunyn Schmiedebergs Arch Pharmacol (1986) 1.22

Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure. J Neurosci (1982) 1.16

Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis. J Neurochem (1997) 1.11

Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain. Neuropsychopharmacology (1996) 1.01

How long should pindolol be associated with paroxetine to improve the antidepressant response? J Clin Psychopharmacol (1997) 1.00

Effect of 5-HT1A receptor antagonists on citalopram-induced increase in extracellular serotonin in the frontal cortex, striatum and dorsal hippocampus. Neuropharmacology (1997) 0.96

Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. J Neurochem (1993) 0.96

Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo. Br J Pharmacol (1997) 0.92

Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors? Eur J Pharmacol (1986) 0.92

Induction of hypothermia as a model of 5-hydroxytryptamine1A receptor-mediated activity in the rat: a pharmacological characterization of the actions of novel agonists and antagonists. J Pharmacol Exp Ther (1993) 0.91

5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. Eur J Pharmacol (1994) 0.91

The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain. Neurosci Lett (1996) 0.90

Anpirtoline, a novel, highly potent 5-HT1B receptor agonist with antinociceptive/antidepressant-like actions in rodents. Br J Pharmacol (1992) 0.88

Autoreceptor antagonists enhance the effect of the reuptake inhibitor citalopram on extracellular 5-HT: this effect persists after repeated citalopram treatment. Neuropharmacology (1997) 0.87

(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain. Naunyn Schmiedebergs Arch Pharmacol (1993) 0.87

Serotonin-containing neurons in brain: depression of firing by monoamine oxidase inhibitors. Science (1970) 0.86

Agonist and antagonist actions of (-)pindolol at recombinant, human serotonin1A (5-HT1A) receptors. Neuropsychopharmacology (1998) 0.86

Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo. Br J Pharmacol (1998) 0.86

Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. Eur J Pharmacol (1996) 0.84

Effect of various antidepressant drugs on the spontaneous firing rate of locus coeruleus and dorsal raphe neurons of the rat. Eur J Pharmacol (1979) 0.83

(-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors. Neuropharmacology (1996) 0.83

Modulation of the activity of central serotoninergic neurons by novel serotonin1A receptor agonists and antagonists: a comparison to adrenergic and dopaminergic neurons in rats. J Pharmacol Exp Ther (1995) 0.83

WAY 100,135 and (-)-tertatolol act as antagonists at both 5-HT1A autoreceptors and postsynaptic 5-HT1A receptors in vivo. Eur J Pharmacol (1993) 0.83

Assessment of relative efficacies of 5-HT1A receptor ligands by means of in vivo animal models. Eur J Pharmacol (1996) 0.82

Pindolol augmentation of treatment-resistant depressed patients. J Clin Psychiatry (1997) 0.82

In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. J Pharmacol Exp Ther (1993) 0.82

Inhibition of 5-HT cell firing in the DRN by non-selective 5-HT reuptake inhibitors: studies on the role of 5-HT1A autoreceptors and noradrenergic mechanisms. Psychopharmacology (Berl) (1997) 0.81

Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors. Eur J Pharmacol (1993) 0.81

(-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine. Eur J Pharmacol (1996) 0.79

Sumatriptan inhibits the release of CGRP and substance P from the rat spinal cord. Neuroreport (1996) 0.79

Tertatolol, a new beta-blocker, is a serotonin (5-hydroxytryptamine1A) receptor antagonist in rat brain. J Pharmacol Exp Ther (1993) 0.78

Effects of imipramine on raphe nuclei and prefrontal cortex extracellular serotonin levels in the rat. Psychopharmacology (Berl) (1997) 0.77

Effects of co-administration of a monoamine oxidase inhibitor and a 5-HT1A receptor antagonist on 5-hydroxytryptamine cell firing and release. Eur J Pharmacol (1997) 0.77

The antiaggressive potency of (-)-penbutolol involves both 5-HT1A and 5-HT1B receptors and beta-adrenoceptors. Eur J Pharmacol (1996) 0.77

Articles by these authors

A review of central 5-HT receptors and their function. Neuropharmacology (1999) 6.13

Relapse of depression after rapid depletion of tryptophan. Lancet (1997) 2.61

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. J Neurosci (2004) 2.35

Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment. Arch Gen Psychiatry (2000) 2.25

Acute SSRI administration affects the processing of social cues in healthy volunteers. Neuropsychopharmacology (2003) 2.14

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol (2008) 2.11

Cross infection control measures and the treatment of patients at risk of Creutzfeldt Jakob disease in UK general dental practice. Br Dent J (2001) 2.08

The role of breakfast in the treatment of obesity: a randomized clinical trial. Am J Clin Nutr (1992) 1.83

Covariation of activity in habenula and dorsal raphé nuclei following tryptophan depletion. Neuroimage (1999) 1.65

Neurochemical and anatomical identification of fast- and slow-firing neurones in the rat dorsal raphe nucleus using juxtacellular labelling methods in vivo. Neuroscience (2003) 1.61

Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease. Lancet (1990) 1.61

In vivo measurement of dopamine and its metabolites by intracerebral dialysis: changes after d-amphetamine. J Neurochem (1983) 1.60

Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort. Psychopharmacology (Berl) (2004) 1.58

The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers. Psychopharmacology (Berl) (2002) 1.56

Brain 5-HT neurotransmission during paroxetine treatment. Br J Psychiatry (1998) 1.48

Fluoxetine and suicidal behaviour. Some clinical and theoretical aspects of a controversy. Br J Psychiatry (1992) 1.48

An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat. Neuroscience (1998) 1.47

Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Mol Psychiatry (2004) 1.45

A single dose of citalopram increases fear recognition in healthy subjects. J Psychopharmacol (2007) 1.43

The effect of prolonged pneumoperitoneum on renal function in an animal model. J Am Coll Surg (1996) 1.41

The effect of the serotonin transporter polymorphism (5-HTTLPR) on amygdala function: a meta-analysis. Mol Psychiatry (2012) 1.40

Brain 5-HT function in obsessive-compulsive disorder. Prolactin responses to d-fenfluramine. Br J Psychiatry (1997) 1.40

Evaluation of first night effect using ambulatory monitoring and automatic sleep stage analysis. Sleep (1988) 1.39

Abstinence symptoms after withdrawal of tranquillising drugs: is there a common neurochemical mechanism? Lancet (1982) 1.39

A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis. Brain Res (1987) 1.36

Oxytocin enhances processing of positive versus negative emotional information in healthy male volunteers. J Psychopharmacol (2008) 1.34

Evidence for a role of GABA interneurones in the cortical modulation of midbrain 5-hydroxytryptamine neurones. Neuroscience (2001) 1.30

Confounding effects of anesthesia on functional activation in rodent brain: a study of halothane and alpha-chloralose anesthesia. Neuroimage (2005) 1.30

Abnormalities of sleep in patients with the chronic fatigue syndrome. BMJ (1993) 1.29

Tryptophan depletion decreases the recognition of fear in female volunteers. Psychopharmacology (Berl) (2003) 1.28

Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT. Br J Pharmacol (1995) 1.26

Tryptophan depletion in normal volunteers produces selective impairments in learning and memory. Neuropharmacology (1994) 1.26

'It's not over when it's over': persistent neurobiological abnormalities in recovered depressed patients. Psychol Med (2008) 1.23

In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC. Eur J Pharmacol (1988) 1.14

Slow wave sleep in humans: role of 5-HT2A and 5-HT2C receptors. Neuropharmacology (1994) 1.14

Electrophysiological evidence for convergence of inputs from the medial prefrontal cortex and lateral habenula on single neurons in the dorsal raphe nucleus. Eur J Neurosci (2003) 1.13

Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brain. J Biol Chem (2000) 1.12

Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release. Psychopharmacology (Berl) (1999) 1.12

Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis. J Neurochem (1997) 1.11

Role of the medial prefrontal cortex in 5-HT1A receptor-induced inhibition of 5-HT neuronal activity in the rat. Br J Pharmacol (1999) 1.10

Short-term SSRI treatment normalises amygdala hyperactivity in depressed patients. Psychol Med (2012) 1.09

Unusual interactions of benzodiazepine receptor antagonists. Nature (1982) 1.08

Tyrosine depletion attenuates dopamine function in healthy volunteers. Psychopharmacology (Berl) (2001) 1.08

The effects of chronic administration of hydrocortisone on cognitive function in normal male volunteers. Psychopharmacology (Berl) (1999) 1.07

Dieting reduces plasma tryptophan and alters brain 5-HT function in women. Psychol Med (1990) 1.07

Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience (2000) 1.06

Studies on the post-ictal rise in seizure threshold. Eur J Pharmacol (1981) 1.05

Administration of the beta-adrenoceptor blocker propranolol impairs the processing of facial expressions of sadness. Psychopharmacology (Berl) (2001) 1.04

Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry. Neuroscience (2000) 1.04

Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness. Br J Psychiatry (2001) 1.04

Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience (1995) 1.03

Cortisol, serotonin and depression: all stressed out? Br J Psychiatry (2002) 1.03

Use of a dietary manipulation to deplete plasma tyrosine and phenylalanine in healthy subjects. J Psychopharmacol (1996) 1.03

The effects of chronic ritanserin treatment on sleep and the neuroendocrine response to L-tryptophan. Psychopharmacology (Berl) (1987) 1.02

Measurement of the proportion of free to total prostate-specific antigen improves diagnostic performance of prostate-specific antigen in the diagnostic gray zone of total prostate-specific antigen. Urology (1995) 1.02

In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism. Br J Pharmacol (2006) 1.02

Effect of pharmacologic treatments on the sleep of depressed patients. Biol Psychiatry (1995) 1.02

Increased neural response to fear in patients recovered from depression: a 3T functional magnetic resonance imaging study. Psychol Med (2009) 1.01

Atenolol reduces plasma melatonin concentration in man. Br J Clin Pharmacol (1983) 1.01

Power of exclusion for parentage verification and probability of match for identity in American Kennel Club breeds using 17 canine microsatellite markers. Anim Genet (2004) 1.01

Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine. Naunyn Schmiedebergs Arch Pharmacol (1995) 1.01

Biological mesh reconstruction of perineal wounds following enhanced abdominoperineal excision of rectum (APER). Int J Colorectal Dis (2011) 1.01

Serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) do not affect the availability of 5-HTT to [11C] DASB binding in the living human brain. Neuroimage (2010) 1.00

Not fade away: the HPA axis and depression. Psychol Med (2010) 0.99

Nutrient balance in humans: effects of diet composition. Am J Clin Nutr (1991) 0.98

The development and use of standardized assessment of abnormal personality. Psychol Med (1981) 0.98

SSRI administration reduces resting state functional connectivity in dorso-medial prefrontal cortex. Mol Psychiatry (2011) 0.98

Changes in blood lipids during six days of overfeeding with medium or long chain triglycerides. J Lipid Res (1990) 0.98

Comparative studies of Cu-64-ATSM and C-11-acetate in an acute myocardial infarction model: ex vivo imaging of hypoxia in rats. Nucl Med Biol (1999) 0.98

Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats. Nature (1981) 0.97

Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. Lancet (1983) 0.96

Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion. Br J Psychiatry (1999) 0.96

Welfare aspects of vertebrate pest control and culling: ranking control techniques for humaneness. Rev Sci Tech (2014) 0.96

Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. Life Sci (1991) 0.96

A study of attachment loss patterns in survivor teeth at 18 months, 36 months and 5 years in community-dwelling older adults. J Periodontal Res (1997) 0.95

5-HT2C receptor activation decreases appetite and body weight in obese subjects. Psychopharmacology (Berl) (1997) 0.95

On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock. Neuropharmacology (1980) 0.95

Acute administration of nutritionally sourced tryptophan increases fear recognition. Psychopharmacology (Berl) (2003) 0.93

A cognitive neuropsychological model of antidepressant drug action. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.93

Direct effects of diazepam on emotional processing in healthy volunteers. Psychopharmacology (Berl) (2008) 0.93

Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function. Neuropharmacology (2007) 0.93

Low-dose citalopram as a 5-HT neuroendocrine probe. Psychopharmacology (Berl) (2001) 0.93

Measuring endogenous changes in serotonergic neurotransmission in humans: a [11C]CUMI-101 PET challenge study. Mol Psychiatry (2012) 0.93

Cerebellar responses during anticipation of noxious stimuli in subjects recovered from depression. Functional magnetic resonance imaging study. Br J Psychiatry (2002) 0.93

Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635. Nucl Med Biol (2000) 0.93

The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study. Mol Psychiatry (2007) 0.92

Dose-related effects of selective 5-HT2 receptor antagonists on slow wave sleep in humans. Psychopharmacology (Berl) (1990) 0.92

Plasma concentrations of tryptophan and dieting. BMJ (1990) 0.92

Evaluation of an alternating-calorie diet with and without exercise in the treatment of obesity. Am J Clin Nutr (1989) 0.92

Evidence that central 5-HT2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat. Br J Pharmacol (2003) 0.91

A comparison of the locomotor effects induced by centrally injected TRH and TRH analogues. Regul Pept (1984) 0.91

Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo. Br J Pharmacol (2009) 0.91

Acute citalopram administration produces correlated increases in plasma and salivary cortisol. Psychopharmacology (Berl) (2002) 0.91

Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors. Br J Pharmacol (1990) 0.91

Comparison of the effects of alpha-methyl-p-tyrosine and a tyrosine-free amino acid load on extracellular noradrenaline in the rat hippocampus in vivo. J Psychopharmacol (1999) 0.91

Lithium increases slow wave sleep: possible mediation by brain 5-HT2 receptors? Psychopharmacology (Berl) (1989) 0.91

Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers. Psychopharmacology (Berl) (2008) 0.91