UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation.

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Published in Br J Pharmacol on April 01, 1999

Authors

D C Hanson1, A Nguyen, R J Mather, H Rauer, K Koch, L E Burgess, J P Rizzi, C B Donovan, M J Bruns, P C Canniff, A C Cunningham, K A Verdries, E Mena, J C Kath, G A Gutman, M D Cahalan, S Grissmer, K G Chandy

Author Affiliations

1: Pfizer Inc., Central Research Division, Groton, Connecticut 06340, USA.

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