PubRank

R B Dickson

Author PubWeight™ 147.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Evidence that transforming growth factor-beta is a hormonally regulated negative growth factor in human breast cancer cells. Cell 1987 3.45
2 Multicolour spectral karyotyping of mouse chromosomes. Nat Genet 1996 2.90
3 Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J Biol Chem 2000 2.47
4 Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells. Proc Natl Acad Sci U S A 1984 2.42
5 c-Myc in breast cancer. Endocr Relat Cancer 2000 2.32
6 alpha 2-macroglobulin adsorbed to colloidal gold: a new probe in the study of receptor-mediated endocytosis. J Cell Biol 1981 2.19
7 C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance. Br J Cancer 2000 2.14
8 Estrogenic regulation of growth and polypeptide growth factor secretion in human breast carcinoma. Endocr Rev 1987 2.07
9 Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk. J Biol Chem 1999 1.93
10 Amantadine and dansylcadaverine inhibit vesicular stomatitis virus uptake and receptor-mediated endocytosis of alpha 2-macroglobulin. Proc Natl Acad Sci U S A 1982 1.76
11 Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol Endocrinol 1987 1.72
12 Isolation and characterization of a highly enriched preparation of receptosomes (endosomes) from a human cell line. Proc Natl Acad Sci U S A 1983 1.68
13 Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity. J Biol Chem 1999 1.62
14 Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. Proc Natl Acad Sci U S A 1987 1.61
15 Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance. Mol Endocrinol 1988 1.59
16 Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells. Cancer Res 1986 1.58
17 Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo. Am J Pathol 2001 1.57
18 Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor. Eur J Biochem 2001 1.49
19 Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis. Oncogene 2008 1.48
20 Prelysosomal divergence of transferrin and epidermal growth factor during receptor-mediated endocytosis. Biochemistry 1983 1.46
21 Characterization of estrogen responsive transforming activity in human breast cancer cell lines. Cancer Res 1986 1.44
22 Matrix metalloproteinase inhibitors. Invest New Drugs 1997 1.43
23 Estrogen-induced factors of breast cancer cells partially replace estrogen to promote tumor growth. Science 1986 1.41
24 Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization. J Biol Chem 1997 1.36
25 Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells. J Natl Cancer Inst 1992 1.36
26 Receptor-mediated endocytosis in cultured fibroblasts: cryptic coated pits and the formation of receptosomes. J Histochem Cytochem 1981 1.35
27 Dual regulation of proliferation and apoptosis: c-myc in bitransgenic murine mammary tumor models. Oncogene 2000 1.29
28 A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV-cmyc transgenic mice. Genes Chromosomes Cancer 1999 1.26
29 Estrogen receptor in adult male rat liver. Endocrinology 1978 1.26
30 Oncogene-induced basement membrane invasiveness in human mammary epithelial cells. Clin Exp Metastasis 1994 1.24
31 Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene. Proc Natl Acad Sci U S A 1987 1.22
32 Induction of epidermal growth factor-related polypeptides by 17 beta-estradiol in MCF-7 human breast cancer cells. Endocrinology 1986 1.19
33 Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. Br J Cancer 2004 1.19
34 Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo. Proc Natl Acad Sci U S A 1989 1.19
35 Binding and internalization of 125I-alpha 2-macroglobulin by cultured fibroblasts. J Biol Chem 1981 1.17
36 Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-alpha genes on in vitro transformation of human mammary epithelial cells. Mol Carcinog 1992 1.17
37 Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells. Cancer Res 1993 1.14
38 Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions. Crit Rev Oncol Hematol 1992 1.13
39 Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice. Cancer Res 1993 1.12
40 Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ. Cancer Res 1993 1.12
41 Estrogen and phorbol esters regulate amphiregulin expression by two separate mechanisms in human breast cancer cell lines. Endocrinology 1995 1.11
42 The EGF receptor system as a target for antitumor therapy. Cancer Invest 1991 1.11
43 8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer. Breast Cancer Res Treat 1986 1.11
44 Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis. Cell Growth Differ 1995 1.10
45 Roles of the matrix metalloproteinases in mammary gland development and cancer. Breast Cancer Res Treat 1998 1.09
46 Control of human breast cancer by estrogen, growth factors, and oncogenes. Cancer Treat Res 1988 1.08
47 A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo. Mol Endocrinol 1988 1.08
48 Induction of ductal morphogenesis and lobular hyperplasia by amphiregulin in the mouse mammary gland. Cell Growth Differ 1996 1.08
49 A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine. J Biol Chem 1992 1.08
50 Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability. Oncogene 1998 1.07
51 Growth factors, apoptosis, and survival of mammary epithelial cells. J Mammary Gland Biol Neoplasia 1999 1.06
52 ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness. Cancer Res 1989 1.06
53 Autocrine and paracrine growth regulation of human breast cancer. J Steroid Biochem 1986 1.06
54 Production of and responsiveness to transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. Cancer Res 1989 1.05
55 EGF receptor expression, regulation, and function in breast cancer. Breast Cancer Res Treat 1994 1.03
56 Transforming growth factors type beta 1 and beta 2 are equipotent growth inhibitors of human breast cancer cell lines. J Cell Physiol 1989 1.03
57 Expression and ligand binding of alpha 2 beta 1 integrin on breast carcinoma cells. Clin Exp Metastasis 1995 1.01
58 The role of cathepsin D in the invasiveness of human breast cancer cells. Cancer Res 1993 1.01
59 Internalization of alpha 2 macroglobulin in receptosomes. Studies with monovalent electron microscopic markers. Exp Cell Res 1981 0.99
60 Regulation of motility and protease expression in PKC-mediated induction of MCF-7 breast cancer cell invasiveness. Exp Cell Res 1999 0.98
61 Transforming growth factor beta 1 induces cachexia and systemic fibrosis without an antitumor effect in nude mice. Cancer Res 1991 0.98
62 Defining a role for c-Myc in breast tumorigenesis. Breast Cancer Res Treat 1997 0.97
63 Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis. Oncogene 2000 0.97
64 Tyrosine kinase receptor--nuclear protooncogene interactions in breast cancer. Cancer Treat Res 1992 0.97
65 Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase. J Med Chem 2001 0.97
66 Growth regulation of human breast carcinoma occurs through regulated growth factor secretion. J Cell Biochem 1987 0.96
67 Differential alteration of stem and other cell populations in ducts and lobules of TGFalpha and c-Myc transgenic mouse mammary epithelium. Tissue Cell 2005 0.95
68 Post-transcriptional destabilization of estrogen receptor mRNA in MCF-7 cells by 12-O-tetradecanoylphorbol-13-acetate. J Biol Chem 1991 0.95
69 Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase. Bioorg Med Chem Lett 2001 0.95
70 The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo. Mol Endocrinol 1989 0.95
71 Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens. Cancer Res 1988 0.94
72 Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cells. Endocrinology 1990 0.94
73 c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells. Br J Cancer 2003 0.94
74 Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells. Mol Endocrinol 1989 0.94
75 Mechanisms of growth control in normal and malignant breast epithelium. Recent Prog Horm Res 1989 0.93
76 The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice. Clin Cancer Res 1996 0.93
77 The process of malignant progression in human breast cancer. Ann Oncol 1990 0.93
78 Multihormonal regulation of insulin-like growth factor-I-related protein in MCF-7 human breast cancer cells. Mol Endocrinol 1988 0.93
79 Cooperation of TGF alpha and c-Myc in mouse mammary tumorigenesis: coordinated stimulation of growth and suppression of apoptosis. Oncogene 1996 0.92
80 Tissue culture conditions determine the effects of estrogen and growth factors on the anchorage independent growth of human breast cancer cell lines. J Steroid Biochem Mol Biol 1991 0.91
81 Ultrastructure of the putative stem cell niche in rat mammary epithelium. Tissue Cell 2003 0.91
82 Receptor-mediated endocytosis of alpha 2-macroglobulin: inhibition by ionophores and stimulation by Na+ and HCO3(-). Ann N Y Acad Sci 1982 0.91
83 Reversible and irreversible inhibitors of clustering of alpha 2M in clathrin-coated pits on the surface of fibroblasts. Exp Cell Res 1982 0.90
84 Tamoxifen-resistant fibroblast growth factor-transfected MCF-7 cells are cross-resistant in vivo to the antiestrogen ICI 182,780 and two aromatase inhibitors. Clin Cancer Res 1998 0.89
85 The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells. Biochem Biophys Res Commun 1989 0.88
86 Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol 1991 0.88
87 Endocrine therapy of human breast cancer cells: the role of secreted polypeptide growth factors. Cancer Cells 1989 0.88
88 Stromal influences on transformation of human mammary epithelial cells overexpressing c-myc and SV40T. J Cell Physiol 1990 0.87
89 Hormonal control of human breast cancer cell lines. Cancer Surv 1986 0.87
90 Binding and internalization of alpha 2-microglobulin by cultured fibroblasts. Effects of monovalent ionophores. Exp Cell Res 1982 0.86
91 Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc. Oncogene 2001 0.85
92 Epidermal growth factor-dependent cell cycle progression is altered in mammary epithelial cells that overexpress c-myc. Clin Cancer Res 1998 0.85
93 Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice. Mol Carcinog 1996 0.85
94 An unusual sex steroid-binding protein in mature male rat liver cytosol. Endocrinology 1978 0.85
95 Antiestrogen resistance in ER positive breast cancer cells. Breast Cancer Res Treat 1994 0.84
96 Growth factor and sex steroid interactions in breast cancer. J Mammary Gland Biol Neoplasia 1996 0.84
97 Modulation by estrogen and growth factors of transforming growth factor-alpha and epidermal growth factor receptor expression in normal and malignant human mammary epithelial cells. Recent Results Cancer Res 1989 0.83
98 Progestins and antiprogestins in mammary tumour growth and metastasis. Hum Reprod 1994 0.83
99 17 Alpha-ethinyl estradiol is more potent than estradiol in receptor interactions with isolated hepatic parenchymal cells. Endocrinology 1981 0.83
100 Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice. Br J Cancer 2004 0.83
101 Growth regulatory peptide production by human breast carcinoma cells. J Steroid Biochem 1988 0.83
102 Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways. Cell Growth Differ 1994 0.82
103 Mitogenic regulation of normal and malignant breast epithelium. Yale J Biol Med 1990 0.82
104 Transforming growth factor-beta induces platelet-derived growth factor (PDGF) messenger RNA and PDGF secretion while inhibiting growth in normal human mammary epithelial cells. Mol Endocrinol 1990 0.82
105 Growth control of normal and malignant breast epithelium. Prog Clin Biol Res 1990 0.82
106 The inter-relationships between ovarian-independent growth, tumorigenicity, invasiveness and antioestrogen resistance in the malignant progression of human breast cancer. J Endocrinol 1989 0.82
107 Transgenic mouse models of breast cancer. Breast Cancer Res Treat 1996 0.82
108 Regulation of the expression of c-Myc by beta1 integrins in epithelial cells. Oncogene 2001 0.81
109 Expression of 67 kDa laminin receptor in human breast cancer cells: regulation by progestins. Clin Exp Metastasis 1993 0.81
110 Role for Bcl-xL in the regulation of apoptosis by EGF and TGF beta 1 in c-myc overexpressing mammary epithelial cells. Biochem Biophys Res Commun 1996 0.80
111 Stress influence on development of hepatocellular tumors in transgenic mice overexpressing TGF alpha. Acta Oncol 1995 0.79
112 Postsurgical oral administration of uracil and tegafur inhibits progression of micrometastasis of human breast cancer cells in nude mice. Clin Cancer Res 1997 0.79
113 Dual regulation of the epidermal growth factor family of growth factors in breast cancer by sex steroids and protein kinase C. J Steroid Biochem Mol Biol 1996 0.79
114 Activation of protein kinase C by phorbol esters modulates alpha2beta1 integrin on MCF-7 breast cancer cells. Exp Cell Res 1999 0.78
115 Female and male green monkey liver estrogen receptor. Biochem Pharmacol 1979 0.78
116 Estrogens regulate production of specific growth factors in hormone-dependent human breast cancer. Ann N Y Acad Sci 1986 0.77
117 Estrogen receptor in rat liver: translocation to the nucleus in isolated parenchymal cells. Endocrinology 1979 0.77
118 Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat. Breast Cancer Res Treat 2001 0.77
119 Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. Cancer Res 1989 0.77
120 Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis. Breast Cancer Res Treat 1996 0.77
121 Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGF alpha mice. Brain Res 1992 0.77
122 Characterization of a novel amphiregulin-related molecule in 12-O-tetradecanoylphorbol-13-acetate-treated breast cancer cells. J Cell Physiol 1996 0.77
123 The cellular response of human breast cancer to estrogen. Prog Clin Biol Res 1988 0.77
124 Purification and characterization of a novel growth factor from human breast cancer cells. Biochemistry 1992 0.77
125 Involvement of Na+ and HCO-3 in receptor-mediated endocytosis of alpha 2-macroglobulin, epidermal growth factor, and vesicular stomatitis virus. J Cell Physiol 1982 0.77
126 Mechanisms of normal and malignant breast epithelial growth regulation. J Steroid Biochem 1989 0.76
127 Estrogens regulate production of specific growth factors in hormone-dependent human breast cancer. J Lab Clin Med 1987 0.76
128 Regulation of breast cancer cells by hormones and growth factors: effects on proliferation and basement membrane invasiveness. Horm Res 1989 0.76
129 The role of erbB-2 and its ligands in growth control of malignant breast epithelium. J Steroid Biochem Mol Biol 1992 0.76
130 Estrogen receptors in the male. Arch Androl 1981 0.76
131 Are cellular adhesion molecules involved in the metastasis of breast cancer? Breast Cancer Res Treat 1994 0.76
132 Detection of cyclin messenger RNAs by nonradioactive ribonuclease protection assay: a comparison of four detection methods. Biotechniques 1995 0.76
133 Assay of mitogen-induced effects on cellular incorporation of precursors for scavenger, de novo, and net DNA synthesis. Methods Enzymol 1987 0.75
134 Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility. Br J Cancer 1993 0.75
135 A breast cancer Website. Breast Cancer Res Treat 1999 0.75
136 Regulation of basement membrane invasiveness in human breast cancer model systems. Mol Cell Endocrinol 1991 0.75
137 Growth factors, oncogenes and anti-oncogenes in cancer. Trends Pharmacol Sci 1989 0.75
138 Characterization of mammary-derived growth factor 1 receptors and response in human mammary epithelial cell lines. J Biol Chem 1990 0.75
139 Receptor-bound estrogens and their metabolites in the nucleus of the isolated rat liver parenchymal cell. Mol Pharmacol 1980 0.75
140 Inhibition by bacitracin of high affinity binding of 125I-alpha 2M to plasma membranes. FEBS Lett 1981 0.75
141 Microinjection of anticlathrin antibodies into cultured fibroblasts: clathrin-coated structures in receptor-mediated endocytosis and in exocytosis. Cold Spring Harb Symp Quant Biol 1982 0.75
142 The role of growth factors in breast cancer. A panel discussion. Breast Cancer Res Treat 1988 0.75
143 Production and characterization of mammary-derived growth factor 1 in mammary epithelial cell lines. Biochemistry 1992 0.75
144 Estrogen receptor in liver of male and female rats: endocrine regulation and molecular properties. Biol Reprod 1979 0.75
145 Isolation of receptosomes (endosomes) from human KB cells. Methods Enzymol 1985 0.75
146 Application of flow cytometry in the analysis and sterile sorting of cell populations based on integrin expression. Methods Mol Biol 1999 0.75
147 Invasion-inhibiting factor 2-albumin conjugate inhibits invasion and spontaneous metastasis of MKL-4 human breast cancer cells transplanted into female nude mice. Clin Exp Metastasis 1996 0.75
148 Secreted and cellular polypeptide patterns of MCF-7 human breast cancer cells following either estrogen stimulation or v-H-ras transfection. Cancer Res 1989 0.75
149 The role of erbB-2 and its ligands in growth control of malignant breast epithelium. Princess Takamatsu Symp 1991 0.75
150 Steroid hormone-growth factor interactions in proliferative controls of the mammary gland and breast cancer: a rapidly evolving perspective. J Steroid Biochem Mol Biol 2002 0.75
151 Mechanisms of hormone and cytotoxic drug interactions in the development and treatment of breast cancer. Prog Clin Biol Res 1990 0.75
152 MDGF1: a multifunctional growth factor in human milk and human breast cancer. Cancer Treat Res 1994 0.75
153 Molecular aspects of breast cancer. J Mammary Gland Biol Neoplasia 1996 0.75
154 In vitro nuclear translocation of the estrogen receptor in the hepatic parenchymal cell from male rats. Mol Pharmacol 1980 0.75
155 Receptor-induced phosphorylation by mammary-derived growth factor 1 in mammary epithelial cell lines. J Biol Chem 1992 0.75