Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain.

PubWeight™: 1.11‹?› | Rank: Top 10%

🔗 View Article (PMID 10386984)

Published in J Neurochem on July 01, 1999

Authors

N Laflamme1, S Rivest

Author Affiliations

1: Laboratory of Molecular Endocrinology, CHUL Research Center and Laval University, Sainte-Foy, Quebec, Canada.

Associated clinical trials:

Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia | NCT01082588

Articles citing this

NF-kappaB in neuronal plasticity and neurodegenerative disorders. J Clin Invest (2001) 2.78

MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem (2008) 1.86

Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infect Immun (2009) 1.18

A systematic analysis of the peripheral and CNS effects of systemic LPS, IL-1β, [corrected] TNF-α and IL-6 challenges in C57BL/6 mice. PLoS One (2013) 1.08

Hypothalamic mechanisms in cachexia. Physiol Behav (2010) 1.04

Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect Immun (2008) 1.04

LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-gamma-independent manner by a JNK signaling pathway in primary murine microglia. Brain Behav Immun (2009) 0.95

Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons. J Neuroinflammation (2014) 0.93

Why is neuroimmunopharmacology crucial for the future of addiction research? Neuropharmacology (2013) 0.89

The vasculome of the mouse brain. PLoS One (2012) 0.89

Immune-to-brain signaling and central prostaglandin E2 synthesis in fasted rats with altered lipopolysaccharide-induced fever. Am J Physiol Regul Integr Comp Physiol (2008) 0.85

Protein metabolism in slow- and fast-twitch skeletal muscle during turpentine-induced inflammation. Int J Exp Pathol (2008) 0.83

Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model. PLoS One (2012) 0.82

IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults. Front Cell Neurosci (2013) 0.82

Neuropeptides in the pathophysiology and treatment of cachexia. Curr Opin Support Palliat Care (2010) 0.82

Lipopolysacharide Rapidly and Completely Suppresses AgRP Neuron-Mediated Food Intake in Male Mice. Endocrinology (2016) 0.81

Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents. Endocrinology (2014) 0.79

Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus. J Neuroinflammation (2014) 0.78

Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells. Infect Immun (2014) 0.77

Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain. J Neuroinflammation (2013) 0.76

Effects of cordycepin on the microglia-overactivation-induced impairments of growth and development of hippocampal cultured neurons. PLoS One (2015) 0.76

Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice. Fluids Barriers CNS (2015) 0.76

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity. Front Aging Neurosci (2017) 0.75

Articles by these authors

Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J (2001) 2.41

Neuroprotective role of the innate immune system by microglia. Neuroscience (2007) 1.83

Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype. J Neurobiol (1998) 1.76

The LPS receptor (CD14) links innate immunity with Alzheimer's disease. FASEB J (2003) 1.75

Effect of stress on the activity of the hypothalamic-pituitary-gonadal axis: peripheral and central mechanisms. Biol Reprod (1991) 1.72

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior. J Neurosci (1994) 1.65

An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia. J Neurosci (1999) 1.55

Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kappa B activity in the brain during endotoxemia. J Neurosci (2000) 1.45

Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS. J Neurochem (2001) 1.41

Effects of circulating tumor necrosis factor on the neuronal activity and expression of the genes encoding the tumor necrosis factor receptors (p55 and p75) in the rat brain: a view from the blood-brain barrier. Neuroscience (1999) 1.40

Innate immune receptor expression in normal brain aging. Neuroscience (2007) 1.34

Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta. J Neurochem (1997) 1.26

Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor. J Immunol (2000) 1.17

The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations. Brain Pathol (1998) 1.16

Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease. Mol Psychiatry (2006) 1.16

Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation. Eur J Neurosci (1999) 1.12

Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain. J Neurochem (1998) 1.11

Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis. Eur J Immunol (2001) 1.11

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation. Mol Psychiatry (2008) 1.11

Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines. J Comp Neurol (2001) 1.10

Corticotropin-releasing factor activates c-fos, NGFI-B, and corticotropin-releasing factor gene expression within the paraventricular nucleus of the rat hypothalamus. Mol Endocrinol (1993) 1.09

Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. Ann Neurol (2001) 1.08

Regulation of the gene encoding tumor necrosis factor alpha (TNF-alpha) in the rat brain and pituitary in response in different models of systemic immune challenge. J Neuropathol Exp Neurol (1999) 1.06

Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer's disease. Genes Brain Behav (2008) 1.01

Effect of a chronic stress on CRF neuronal activity and expression of its type 1 receptor in the rat brain. Am J Physiol (1998) 0.99

Anti-inflammatory effects of prostaglandin E2 in the central nervous system in response to brain injury and circulating lipopolysaccharide. J Neurochem (2001) 0.97

Selective involvement of interleukin-6 in the transcriptional activation of the suppressor of cytokine signaling-3 in the brain during systemic immune challenges. Endocrinology (2000) 0.96

Expression of corticotropin-releasing factor and its receptors in the brain of lean and obese Zucker rats. Endocrinology (1996) 0.93

Interleukin-6 is a needed proinflammatory cytokine in the prolonged neural activity and transcriptional activation of corticotropin-releasing factor during endotoxemia. Endocrinology (1999) 0.92

Effect of immune and metabolic challenges on the luteinizing hormone-releasing hormone neuronal system in cycling female rats: an evaluation at the transcriptional level. Endocrinology (1997) 0.92

Corticotropin-releasing hormone and its receptors; an evaluation at the transcription level in vivo. Peptides (2001) 0.91

Functional circuitry in the brain of immune-challenged rats: partial involvement of prostaglandins. J Comp Neurol (1997) 0.91

The complement system is an integrated part of the natural innate immune response in the brain. FASEB J (2001) 0.91

The role of microglial cell subsets in Alzheimer's disease. Curr Alzheimer Res (2011) 0.90

Role of interdomain salt bridges in the pore-forming ability of the Bacillus thuringiensis toxins Cry1Aa and Cry1Ac. J Biol Chem (2001) 0.89

Fluoxetine induces the transcription of genes encoding c-fos, corticotropin-releasing factor and its type 1 receptor in rat brain. Neuroscience (1998) 0.89

Regulation of corticotropin-releasing factor type 1 (CRF1) receptor messenger ribonucleic acid in the paraventricular nucleus of rat hypothalamus by exogenous CRF. Endocrinology (1996) 0.88

C-fos mRNA pattern and corticotropin-releasing factor neuronal activity throughout the brain of rats injected centrally with a prostaglandin of E2 type. J Neuroimmunol (1996) 0.86

Inhibitory action of nitric oxide on circulating tumor necrosis factor-induced NF-kappaB activity and COX-2 transcription in the endothelium of the brain capillaries. J Neuropathol Exp Neurol (2001) 0.85

Mechanisms mediating the effects of cytokines on neuroendocrine functions in the rat. Ciba Found Symp (1993) 0.85

Analysis of the properties of Bacillus thuringiensis insecticidal toxins using a potential-sensitive fluorescent probe. J Membr Biol (2003) 0.85

Influence of interleukin-6 on neural activity and transcription of the gene encoding corticotrophin-releasing factor in the rat brain: an effect depending upon the route of administration. Eur J Neurosci (1997) 0.84

Influence of the estrous cycle on c-fos and CRH gene transcription in the brain of endotoxin-challenged female rats. Neuroendocrinology (1997) 0.82

Involvement of serotonergic pathways in mediating the neuronal activity and genetic transcription of neuroendocrine corticotropin-releasing factor in the brain of systemically endotoxin-challenged rats. Neuroscience (1999) 0.81

Reduced corticotropin-releasing factor and enhanced vasopressin gene expression in brains of mice with autoimmunity-induced behavioral dysfunction. J Neuroimmunol (1999) 0.81

Neuronal activity and transcription of proinflammatory cytokines, IkappaBalpha, and iNOS in the mouse brain during acute endotoxemia and chronic infection with Trypanosoma brucei brucei. J Neurosci Res (1999) 0.81

Luteinizing hormone secretion and corticotropin-releasing factor gene expression in the paraventricular nucleus of rhesus monkeys following cortisol synthesis inhibition. Endocrinology (1997) 0.80

A functional analysis of EP4 receptor-expressing neurons in mediating the action of prostaglandin E2 within specific nuclei of the brain in response to circulating interleukin-1beta. J Neurochem (2000) 0.80

Ovulatory cycle influences the stimulatory effect of stress on the expression of corticotropin-releasing factor receptor messenger ribonucleic acid in the paraventricular nucleus of the female rat hypothalamus. Endocrinology (1995) 0.79

Cloning of murine TReP-132, a novel transcription factor expressed in brain regions involved in behavioral and psychiatric disorders. Mol Psychiatry (2003) 0.79

Effect of immobilization stress on transcriptional activity of inducible immediate-early genes, corticotropin-releasing factor, its type 1 receptor, and enkephalin in the hypothalamus of borderline hypertensive rats. J Neurochem (1998) 0.77

Effect of dexfenfluramine on the transcriptional activation of CRF and its type 1 receptor within the paraventricular nucleus of the rat hypothalamus. Br J Pharmacol (1996) 0.77

Stress-induced genetic expression of a selective corticotropin-releasing factor-receptor subtype within the rat ovaries: an effect dependent on the ovulatory cycle. Biol Reprod (1995) 0.77

Tissue specificity of SNS response to exercise in mice exposed to low temperatures. Am J Physiol (1992) 0.77

Adrenalectomy attenuates the effect of chemical castration on energy balance in rats. J Nutr (1992) 0.76

Role of cyclo-oxygenase pathways in the stimulatory influence of immune challenge on the transcription of a specific CRF receptor subtype in the rat brain. J Chem Neuroanat (1996) 0.76

The role of exercise in thermogenesis and energy balance. Can J Physiol Pharmacol (1989) 0.76

Corticotropin-releasing factor and glucocorticoid receptor (GR) gene expression in the paraventricular nucleus of immune-challenged transgenic mice expressing type II GR antisense ribonucleic acid. J Mol Neurosci (1997) 0.76

Corticotropin-releasing factor (CRF) and stress-related reproductive failure: the brain as a state of the art or the ovary as a novel clue? J Endocrinol Invest (1995) 0.76

Alcohol-induced inhibition of LH secretion in intact and gonadectomized male and female rats: possible mechanisms. Alcohol Clin Exp Res (1992) 0.76

The 5-hydroxytryptamine agonist fenfluramine increases Fos-like immunoreactivity in the brain. Brain Res (1992) 0.75

Aging female brain: is there a change of adaptive stress? Aging (Milano) (1997) 0.75

Neuronal activation of the hypothalamic magnocellular system in response to oropharyngeal stimuli in the rat. J Neuroendocrinol (1997) 0.75

Reversible increase in energy deposition following castration induced by a gonadotropin releasing hormone agonist. Int J Obes (1991) 0.75

Effects of exercise on energy balance in meal-fed mice. Physiol Behav (1991) 0.75