Alterations in enzymatic antioxidant defence in diabetes mellitus--a rational approach.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 1741099)

Published in Postgrad Med J on January 01, 1999

Authors

E Szaleczky1, J Prechl, J Fehér, A Somogyi

Author Affiliations

1: 2nd Department of Medicine, Semmelweis University of Medicine, Budapest, Hungary.

Articles cited by this

An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase. Proc Natl Acad Sci U S A (1971) 8.82

Role of oxidative stress in development of complications in diabetes. Diabetes (1991) 8.27

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Lancet (1994) 6.71

Strategies of antioxidant defense. Eur J Biochem (1993) 3.60

Free radicals and diabetes. Free Radic Biol Med (1988) 3.22

Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem J (1987) 2.82

Hyperglycemic pseudohypoxia and diabetic complications. Diabetes (1993) 2.62

Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment. Diabetes (1987) 1.58

Copper, zinc, manganese, and magnesium status and complications of diabetes mellitus. Diabetes Care (1991) 1.53

Regulation of antioxidant enzymes. FASEB J (1992) 1.48

Free radicals in diabetic endothelial cell dysfunction. Free Radic Biol Med (1994) 1.42

Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia (1995) 1.16

Effect of insulin and oral glutathione on glutathione levels and superoxide dismutase activities in organs of rats with streptozocin-induced diabetes. Diabetes (1986) 1.16

Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals. Am J Physiol (1994) 1.14

Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am J Physiol (1992) 1.07

Antioxidant enzyme alterations in experimental and clinical diabetes. Mol Cell Biochem (1988) 1.04

Effect of glycemic control, race (white versus black), and duration of diabetes on reduced glutathione content in erythrocytes of diabetic patients. Metabolism (1994) 1.02

Non-enzymic glycation of human extracellular superoxide dismutase. Biochem J (1991) 1.02

Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetis mellitus. J Clin Endocrinol Metab (1992) 0.98

Bioassay of endothelium-derived relaxing factor in diabetic rat aorta. Am J Physiol (1992) 0.97

Glycation (non-enzymic glycosylation) inactivates glutathione reductase. Biochem J (1992) 0.97

Effect of insulin on impaired antioxidant activities in aortic endothelial cells from diabetic rabbits. Metabolism (1992) 0.90

Abnormal glutathione metabolism and increased cytotoxicity caused by H2O2 in human umbilical vein endothelial cells cultured in high glucose medium. Diabetologia (1994) 0.88

Erythrocyte lipid peroxidation and glutathione peroxidase activities in patients with diabetes mellitus. Horm Metab Res (1987) 0.88

Disturbances of micronutrient and antioxidant status in diabetes. Proc Nutr Soc (1991) 0.87

Lipid peroxidation, glutathione levels and changes in glutathione-related enzyme activities in streptozotocin-induced diabetic rats. Immunol Cell Biol (1994) 0.85

Alterations of the plasma selenium concentrations and the activities of tissue peroxide metabolism enzymes in streptozotocin-induced diabetic rats. Horm Metab Res (1988) 0.82

Hydroxyl radicals mediate injury to endothelium-dependent relaxation in diabetic rat. Mol Cell Biochem (1993) 0.82

Antioxidant enzyme status and lipid peroxidation in various tissues of diabetic and starved rats. Diabetes Res (1989) 0.81

[Glutathione metabolism in erythrocytes from patients with diabetes mellitus]. Hokkaido Igaku Zasshi (1991) 0.81

Red cell peroxide metabolism in diabetes mellitus. Horm Metab Res (1987) 0.81

Selenium status and lipoproteins in healthy and diabetic children. J Trace Elem Electrolytes Health Dis (1993) 0.81

Glutathione and glutathione-metabolizing enzymes in the erythrocytes of healthy children and in children with insulin-dependent diabetes mellitus, juvenile rheumatoid arthritis, coeliac disease and acute lymphoblastic leukaemia. Scand J Clin Lab Invest (1991) 0.81

Decreased susceptibility of liver mitochondria from diabetic rats to oxidative damage and associated increase in alpha-tocopherol. Free Radic Biol Med (1993) 0.80

[Experimental models in research of the pathomechanism of diabetes mellitus]. Orv Hetil (1996) 0.77

Articles by these authors

(truncated to the top 100)

Drug interactions with cimetidine. Clin Pharmacokinet (1982) 2.49

Impaired cimetidine absorption due to antacids and metoclopramide. Eur J Clin Pharmacol (1981) 1.86

Early syphilitic hepatitis. Lancet (1975) 1.64

IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease. Immunogenetics (1999) 1.62

Pharmacokinetic interactions of cimetidine 1987. Clin Pharmacokinet (1987) 1.58

Rectal administration of metronidazole provides therapeutic plasma levels in postoperative patients. N Engl J Med (1981) 1.45

Cimetidine-procainamide pharmacokinetic interaction in man: evidence of competition for tubular secretion of basic drugs. Eur J Clin Pharmacol (1983) 1.44

[Chronic gastritis and the presence of Helicobacter pylori in patients with non-ulcerative dyspepsia]. Orv Hetil (1991) 1.39

[Interferon therapy in chronic active viral hepatitis]. Orv Hetil (1995) 1.38

[Cytokine production in patients with systemic lupus erythematosus]. Orv Hetil (1991) 1.38

[Nitric oxide. Basic research and possible clinical use]. Orv Hetil (1996) 1.38

Clinical pharmacokinetics of cimetidine. Clin Pharmacokinet (1984) 1.32

Reduction of metformin renal tubular secretion by cimetidine in man. Br J Clin Pharmacol (1987) 1.29

Surface-induced dissociation: an effective tool to probe structure, energetics and fragmentation mechanisms of protonated peptides. J Mass Spectrom (1996) 1.25

Safety and efficacy of rituximab in nonviral cryoglobulinemia vasculitis: data from the French Autoimmunity and Rituximab registry. Arthritis Care Res (Hoboken) (2010) 1.25

Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis. Br J Clin Pharmacol (1981) 1.23

Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil. Eur J Clin Pharmacol (1984) 1.20

Clinical pharmacology: a declaration of intent. Br J Clin Pharmacol (2010) 1.18

Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone. J Pain Symptom Manage (1996) 1.16

Effects of verapamil on P-R-intervals in relation to verapamil plasma levels following single I.V. and oral administration and during chronic treatment. Klin Wochenschr (1980) 1.16

Fragmentation of protonated peptides: surface-induced dissociation in conjunction with a quantum mechanical approach. Anal Chem (1993) 1.15

Formation of amino acids and nucleotide bases in a Titan atmosphere simulation experiment. Astrobiology (2012) 1.15

A further link between innate and adaptive immunity: C3 deposition on antigen-presenting cells enhances the proliferation of antigen-specific T cells. Int Immunol (1998) 1.14

Thermal decomposition kinetics of protonated peptides and peptide dimers, and comparison with surface-induced dissociation. Rapid Commun Mass Spectrom (1995) 1.11

Simultaneous determination of the intravenous and oral pharmacokinetic parameters of D,L-verapamil using stable isotope-labelled verapamil. Eur J Clin Pharmacol (1981) 1.08

Adjuvant effect of gamma-inulin is mediated by C3 fragments deposited on antigen-presenting cells. J Leukoc Biol (2001) 1.02

Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs. J Pharmacol Exp Ther (1986) 1.02

Pharmacokinetics and bioavailability of cimetidine in gastric and duodenal ulcer patients. Clin Pharmacokinet (1980) 1.02

The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model. J Pharmacol Exp Ther (1994) 1.00

Average activation energies of low-energy fragmentation processes of protonated peptides determined by a new approach. Rapid Commun Mass Spectrom (1996) 0.99

Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes. Arch Biochem Biophys (1972) 0.98

Polymorphous low-grade adenocarcinoma of the nasopharynx. Case report and review of the literature. Strahlenther Onkol (2000) 0.97

Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Studies of the relative bioavailability of verapamil tablets. Eur J Clin Pharmacol (1981) 0.96

Dose and concentration dependent effect of ranitidine on procainamide disposition and renal clearance in man. Br J Clin Pharmacol (1984) 0.94

Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients. J Pain Symptom Manage (1997) 0.93

Influence of meso-caval shunt surgery on verapamil kinetics, bioavailability and response. Br J Clin Pharmacol (1980) 0.92

In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes. Steroids (2000) 0.90

Prediction of bioavailability for drugs with a high first-pass effect using oral clearance data. Eur J Clin Pharmacol (1982) 0.90

Miniature ionization chamber detector developed for X-ray microprobe measurements. J Synchrotron Radiat (2003) 0.90

Application of stable labelled drugs in clinical pharmacokinetic investigations. Clin Pharmacokinet (1983) 0.90

Changes in the glycoprotein fractions of blood serum and lymph in croton oil-induced inflammation. Acta Med Acad Sci Hung (1969) 0.89

Amyloid tumor in the lachrymal gland. Ann Ophthalmol (1971) 0.88

Allelic variation at the interleukin 1beta gene is associated with decreased bone mass in patients with inflammatory bowel diseases. Gut (2001) 0.88

Effects of two bioflavonoids on certain cellular immune reactions in vitro. Acta Physiol Hung (1990) 0.88

Effect of the bioflavonoid silymarin on the in vitro activity and expression of superoxide dismutase (SOD) enzyme. Acta Physiol Hung (1991) 0.88

Cholecystitis, gallstones and free radical reactions in human gallbladder. Med Sci Monit (2001) 0.88

Modulation of the humoral immune response by antibody-mediated antigen targeting to complement receptors and Fc receptors. J Immunol (1999) 0.87

Multicenter evaluation of the Sepsityper™ extraction kit and MALDI-TOF MS for direct identification of positive blood culture isolates using the BD BACTEC™ FX and VersaTREK(®) diagnostic blood culture systems. J Appl Microbiol (2014) 0.87

Looking back: editors' pick of 2008. Br J Clin Pharmacol (2009) 0.87

Inhibition by salicylates of various calcifying connective tissue reactions. Arch Int Pharmacodyn Ther (1969) 0.87

Biochemical markers in carbon-tetrachloride-and galactosamine-induced acute liver injuries: the effects of dihydroquinoline-type antioxidants. Br J Exp Pathol (1982) 0.87

Ultrastructural localization of Hsp-72 examined with a new polyclonal antibody raised against the truncated variable domain of the heat shock protein. Cell Stress Chaperones (1999) 0.87

Significant differences in the interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in a Hungarian population with inflammatory bowel disease. Scand J Gastroenterol (1999) 0.86

Pharmacokinetics and metabolism of antipyrine (phenazone) after intravenous and oral administration. Arzneimittelforschung (1982) 0.86

Increased cell proliferation in chronic Helicobacter pylori positive gastritis and gastric carcinoma--correlation between immuno-histochemistry and Tv image cytometry. Anal Cell Pathol (2000) 0.86

Disposition and removal of metronidazole in patients undergoing haemodialysis. Eur J Clin Pharmacol (1983) 0.85

Effect of alkyl substitution at the amide nitrogen on amide bond cleavage: electrospray ionization/surface-induced dissociation fragmentation of substance P and two alkylated analogs. J Mass Spectrom (1996) 0.85

Effects of strontium on the physicochemical characteristics of hydroxyapatite. Calcif Tissue Int (2004) 0.85

Sensitization by corn oil for the production of cardiac necroses by various steroids and sodium salts. Am J Cardiol (1969) 0.85

[Liver-protective action of silymarin therapy in chronic alcoholic liver diseases]. Orv Hetil (1989) 0.85

Antioxidant defense in erythrocytes and plasma of patients with active and quiescent Crohn disease and ulcerative colitis: a chemiluminescent study. Clin Chem (1999) 0.84

Ultrastructural localization of somatostatin- and substance P-immunoreactive nerve fibers in the feline liver. Gastroenterology (1992) 0.84

Oxidative damage in alcoholic liver disease. Eur J Gastroenterol Hepatol (2001) 0.84

CT densitometry of the brain: a novel method for early detection and assessment of irradiation induced brain edema. Neoplasma (2002) 0.84

In vitro study of elements in herbal remedies. Biol Trace Elem Res (2006) 0.84

Lysosomal enzymes in sera and granulocytes of patients with chronic liver diseases. Int J Tissue React (1981) 0.84

Preserved structural and functional characteristics of common carotid artery in properly treated normoglycemic women with gestational diabetes mellitus. Acta Physiol Hung (2011) 0.83

Successful substitution of rectal metronidazole administration for intravenous use. Lancet (1983) 0.83

Changes induced by vascular antigens in the aorta of guinea-pigs: immunological and morphological studies. Br J Exp Pathol (1978) 0.83

Serum lipids and lipoproteins in chronic liver disease. Acta Med Acad Sci Hung (1976) 0.83

Left ventricular beta 1 and beta 2 adrenoceptor mRNA expression in normal and volume overloaded human heart. Cardiovasc Res (1991) 0.83

Lack of inhibition of tolbutamide hydroxylation by cimetidine in man. Eur J Clin Pharmacol (1986) 0.82

Rapid and sensitive high-performance liquid chromatographic assay for metformin in plasma and urine using ion-pair extraction techniques. J Chromatogr (1986) 0.82

Cardiac rehabilitation in different geographic areas. Adv Cardiol (1986) 0.82

Collagenolysis and regeneration in corneal burnings. Ophthalmologica (1972) 0.82

Ultrastructural changes induced in the liver of rats by various steroid compounds. Virchows Arch B Cell Pathol (1971) 0.82

Comparison of cerebral pharmacokinetics of buprenorphine and norbuprenorphine in an in vivo sheep model. Xenobiotica (2007) 0.82

Inflammation, topical stress and the concept of pluricausal diseases. Biochem Pharmacol (1968) 0.82

Ischemic retinal alterations in cardiac arrest. Ann Ophthalmol (1979) 0.82

Role of endothelin-1 in diabetes mellitus. Diabetes Metab Rev (1998) 0.82

Hepatitis syphilitica. A clinico-pathological study of 25 cases. Acta Hepatogastroenterol (Stuttg) (1977) 0.81

[The observation of edema in the substantia alba during postoperative brain irradiation. The role of computed tomographic studies]. Strahlenther Onkol (1998) 0.81

[Effect of silimarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol)]. Orv Hetil (1990) 0.81

Evaluation of the dose uniformity for double-plane high dose rate interstitial breast implants with the use of dose reference points and dose non-uniformity ratio. Radiother Oncol (2000) 0.81

H1 histamine receptor antagonist inhibits constitutive growth of Jurkat T cells and antigen-specific proliferation of ovalbumin-specific murine T cells. Semin Cancer Biol (2000) 0.81

The effect of superoxide dismutase in the myocardium during reperfusion in the dog. Free Radic Biol Med (1992) 0.81

[Crowned dens syndrome: three new cases]. Rev Med Interne (2003) 0.81

Adrenomedullin and diabetes mellitus. Diabetes Metab Res Rev (2001) 0.80

Evidence of in vivo peroxynitrite formation in patients with colorectal carcinoma, higher plasma nitrate/nitrite levels, and lower protection against oxygen free radicals. J Clin Gastroenterol (2000) 0.80

Acceleration and inhibition of wound healing by topical treatment with different types of inflammatory irritants. Am J Surg (1969) 0.80

The importance of interstitial radiotherapy in the treatment of the base of tongue tumors: a retrospective analysis. Neoplasma (2001) 0.80

Pharmacokinetics of pholcodine in healthy volunteers: single and chronic dosing studies. Br J Clin Pharmacol (1988) 0.80

Corneal toxicity of xylazine and clonidine, in combination with ketamine, in the rat. Ophthalmic Res (2001) 0.80

Biochemical studies on the anticalcinotic effect of sodium salicylate. Can J Physiol Pharmacol (1969) 0.80

Rate measurements of the hydrolysis of complex organic macromolecules in cold aqueous solutions: implications for prebiotic chemistry on the early Earth and Titan. Astrobiology (2008) 0.80

Prevention of renal necrosis by stress. JAMA (1967) 0.79

Protection against dimethylnitrosamine toxicity by pregnenolone-16 -carbonitrile. Nat New Biol (1972) 0.79

The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation. Phytother Res (2000) 0.79

Quantitative measurement of endothelium derived nitric oxide production of the internal mammary artery bypass graft during extracorporeal circulation. Eur J Cardiothorac Surg (2001) 0.79

Effect of the natural bioflavonoid antioxidant silymarin on superoxide dismutase (SOD) activity and expression in vitro. Biotechnol Ther (1993) 0.79