J F Evans

Author PubWeight™ 82.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996 7.46
2 Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 1999 3.57
3 Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990 3.11
4 Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia 2012 3.04
5 Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 2000 2.89
6 Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res 1995 2.74
7 5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J Exp Med 1993 1.95
8 Identification of receptors for neuromedin U and its role in feeding. Nature 2000 1.60
9 Discovery and mapping of ten novel G protein-coupled receptor genes. Gene 2001 1.60
10 Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis. J Biol Chem 1990 1.54
11 Helping patients travel by air. CMAJ 1991 1.50
12 Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 2001 1.49
13 Polycistronic mRNAs code for polypeptides of the Vibrio harveyi luminescence system. J Bacteriol 1985 1.39
14 Mode of action of phenformin plus ethyloestrenol on fibrinolysis. Lancet 1971 1.39
15 Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes. Am J Respir Crit Care Med 2001 1.37
16 Methodological study and a recommended technique for determining the euglobulin lysis time. J Clin Pathol 1968 1.33
17 Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun 1999 1.32
18 The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor. Bioorg Med Chem Lett 1999 1.30
19 A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model. Br J Pharmacol 2010 1.27
20 Normal development following in vitro fertilization in the cow. Biol Reprod 1982 1.21
21 Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitis. Clin Exp Allergy 2003 1.18
22 Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2. Rheumatology (Oxford) 1999 1.16
23 Effect of ethyloestrenol combined with phenformin or with metformin on platelet stickiness and serum-cholesterol in patients with occlusive vascular disease. Lancet 1968 1.13
24 Fibrinolytic and defibrinating effect of phenformin plus ethyloestrenol in vivo. Lancet 1969 1.13
25 Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity. J Biol Chem 1999 1.10
26 Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor. Can J Physiol Pharmacol 1992 1.08
27 Orphan G protein-coupled receptors in the CNS. Curr Opin Pharmacol 2001 1.06
28 Leukotriene A3. A poor substrate but a potent inhibitor of rat and human neutrophil leukotriene A4 hydrolase. J Biol Chem 1985 1.06
29 Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. J Pharmacol Exp Ther 2010 1.04
30 Characterization of a 5-lipoxygenase-activating protein binding assay: correlation of affinity for 5-lipoxygenase-activating protein with leukotriene synthesis inhibition. Mol Pharmacol 1992 0.98
31 Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. Cancer Res 2001 0.97
32 Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase. Biochem Biophys Res Commun 1985 0.96
33 Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells. Biochem Pharmacol 1996 0.96
34 A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells. J Cell Biol 1992 0.96
35 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol 1992 0.95
36 Epidermoid carcinoma of the palate. Am J Surg 1981 0.91
37 Purification and characterisation of leukotriene A4 hydrolase from rat neutrophils. Biochim Biophys Acta 1985 0.90
38 Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors. Mol Pharmacol 1992 0.89
39 Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors. J Biol Chem 1991 0.89
40 In vitro synthesis of subunits of bacterial luciferase in an Escherichia coli system. J Bacteriol 1983 0.88
41 Stage III carcinoma of the breast. A detailed analysis. Ann Surg 1980 0.88
42 Activation of leukocyte movement and displacement of [3H]leukotriene B4 from leukocyte membrane preparations by (12R)- and (12S)-hydroxyeicosatetraenoic acid. Biochim Biophys Acta 1987 0.86
43 Pharmacodynamics and pharmacokinetics of AM103, a novel inhibitor of 5-lipoxygenase-activating protein (FLAP). Clin Pharmacol Ther 2010 0.83
44 Effect of hypophysectomy on the proliferation and differentiation of rat bone marrow stromal cells. Am J Physiol 1999 0.83
45 Cloning and characterization of the human leukotriene A4 hydrolase gene. Eur J Biochem 1995 0.83
46 The pharmacology of L-670,596, a potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist. Can J Physiol Pharmacol 1989 0.83
47 Leukotriene B3, leukotriene B4 and leukotriene B5; binding to leukotriene B4 receptors on rat and human leukocyte membranes. Prostaglandins 1986 0.82
48 Analogs of leukotriene B4: effects of modification of the hydroxyl groups on leukocyte aggregation and binding to leukocyte leukotriene B4 receptors. Prostaglandins 1987 0.82
49 Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells. Mol Pharmacol 1994 0.82
50 Antibody response in the bovine genital tract to intrauterine infusion of Actinomyces pyogenes. Res Vet Sci 1990 0.82
51 A new class of leukotriene biosynthesis inhibitor: the development of MK-0591. J Lipid Mediat 1993 0.81
52 Effects of clofibrate on fibrinolysis, platelet stickiness, plasma-fibrinogen, and serum-cholesterol. Lancet 1968 0.81
53 Effects on platelet stickiness and fibrinolysis of phenformin combined with ethyloestrenol or stanozolol. Lancet 1970 0.80
54 Characterization of monoclonal antibodies against human leukocyte 5-lipoxygenase. Prostaglandins Leukot Essent Fatty Acids 1992 0.80
55 Structural requirements for the binding of fatty acids to 5-lipoxygenase-activating protein. Eur J Pharmacol 1994 0.80
56 Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells. Eur J Biochem 1993 0.80
57 Malignant melanoma and its precursors. The growing need for early identification. Postgrad Med 1986 0.79
58 Dorsomedial hypothalamic lesions alter intake of an imbalanced amino acid diet in rats. J Nutr 1998 0.79
59 Pharmacodynamics, pharmacokinetics, and safety of AM211: a novel and potent antagonist of the prostaglandin D2 receptor type 2. J Clin Pharmacol 2011 0.78
60 Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase. J Med Chem 1995 0.78
61 In vitro fertilization of cow ova. Theriogenology 1978 0.77
62 Effects of dorsomedial hypothalamic nuclei lesions on intake of an imbalanced amino acid diet. Am J Physiol 1999 0.77
63 Fertilization and early development of cow ova. Biol Reprod 1980 0.77
64 Effect of circular motion exercise on bone modeling and bone mass in young rats: an animal model of isometric exercise. J Musculoskelet Neuronal Interact 2001 0.77
65 Neutrophil aggregation and chemokinesis assays. Methods Enzymol 1988 0.77
66 Creating instructional media to meet the needs of preschool hearing-impaired children with developmental disabilities. Am Ann Deaf 1981 0.75
67 In utero conversion of supraventricular tachycardia with digoxin and procainamide at 17 weeks' gestation. Am J Perinatol 1992 0.75
68 A Note on the Pathology of Kala-Azar or Beri-Beri of Assam. Ind Med Gaz 1892 0.75
69 A Note on the Condition of the Blood in Malaria. Br Med J 1888 0.75
70 Regional perinatal care: Kansas/1979. J Kans Med Soc 1980 0.75
71 Leukotriene B4 receptors on rat and human neutrophil membranes. Methods Enzymol 1988 0.75
72 The lipoxins. Stereochemical identification and determination of their biosynthesis. J Biol Chem 1985 0.75
73 The lipoxins: determination of their biosynthesis. Pharmacol Res Commun 1986 0.75
74 Radiation absorbed doses to the walls of hollow organs. J Nucl Med 1998 0.75
75 Aerobic fitness and emotional arousal: a reply to Zimmerman and Fulton. Percept Mot Skills 1982 0.75
76 Studies of retention and stability of a horizontally polymerized bonded phase for reversed-phase liquid chromatography. J Chromatogr A 2000 0.75
77 Aerobic fitness and emotional arousal: a further response to Zimmerman and Fulton. Percept Mot Skills 1983 0.75
78 Erie, PA, hospital achieves 'productivity without trauma'. Hospitals 1984 0.75
79 Structural characterization of the covalent attachment of leukotriene A3 to leukotriene A4 hydrolase. Arch Biochem Biophys 1998 0.75
80 Chemical and enzymatic syntheses of lipoxin A: stereochemical assignment of natural lipoxin A and its possible biosynthesis. Adv Prostaglandin Thromboxane Leukot Res 1985 0.75
81 Inflammatory effector mechanisms in asthma. Am J Respir Crit Care Med 1995 0.75
82 A Note on the Pathology of Kala-Azar, or Beri-Beri, of Assam. Ind Med Gaz 1892 0.75