Published in Ann N Y Acad Sci on June 29, 1999
Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev (2007) 5.22
Accumbens dopamine-acetylcholine balance in approach and avoidance. Curr Opin Pharmacol (2007) 1.35
Candidate genes for antidepressant response to selective serotonin reuptake inhibitors. Neuropsychiatr Dis Treat (2005) 0.86
Natural addiction: a behavioral and circuit model based on sugar addiction in rats. J Addict Med (2009) 0.84
Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice. J Neural Transm (Vienna) (2012) 0.80
Neurobiology of aversive states. Physiol Behav (2011) 0.80
A cholinergic hypothesis of the unconscious in affective disorders. Front Neurosci (2013) 0.78
The Role of Muscarinic Receptors in the Pathophysiology of Mood Disorders:A Potential Noveltreatment? Curr Neuropharmacol (2015) 0.76
Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain. Neuroreport (2001) 2.19
Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience (2005) 2.10
Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity. Neuroscience (2009) 2.09
Restricted eating with weight loss selectively decreases extracellular dopamine in the nucleus accumbens and alters dopamine response to amphetamine, morphine, and food intake. J Neurosci (1995) 1.77
Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response. Neuroscience (2006) 1.71
A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine. Neuroscience (2003) 1.67
Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci (1988) 1.60
Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens. Physiol Behav (1988) 1.50
Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane. J Physiol (1998) 1.29
Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens. Psychopharmacology (Berl) (2001) 1.27
Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain Res (1991) 1.22
A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion. Brain Res (1991) 1.20
Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose. Neuroscience (2008) 1.14
Hyperphagia and obesity following serotonin depletion by intraventricular p-chlorophenylalanine. Science (1976) 1.14
Self-injection of amphetamine directly into the brain. Psychopharmacology (Berl) (1983) 1.13
Effects of feeding and drinking on acetylcholine release in the nucleus accumbens, striatum, and hippocampus of freely behaving rats. J Neurochem (1992) 1.10
Galanin in the hypothalamus raises dopamine and lowers acetylcholine release in the nucleus accumbens: a possible mechanism for hypothalamic initiation of feeding behavior. Brain Res (1998) 1.09
An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release. Pharmacol Biochem Behav (1994) 1.04
Chronic food deprivation decreases extracellular dopamine in the nucleus accumbens: implications for a possible neurochemical link between weight loss and drug abuse. Obes Res (1995) 1.02
Feeding and self-stimulation. Ann N Y Acad Sci (1969) 1.00
Brain neurotransmitters in food and drug reward. Am J Clin Nutr (1985) 1.00
A small, removable microdialysis probe. Life Sci (1986) 1.00
Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain Res (1989) 1.00
In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal. Pharmacol Biochem Behav (2004) 1.00
Weak base model of amphetamine action. Ann N Y Acad Sci (1992) 0.99
Inescapable stress enhances extracellular acetylcholine in the rat hippocampus and prefrontal cortex but not the nucleus accumbens or amygdala. Neuroscience (1996) 0.99
Extracellular acetylcholine is increased in the nucleus accumbens following the presentation of an aversively conditioned taste stimulus. Brain Res (1995) 0.98
Corticotropin-releasing factor in the nucleus accumbens shell induces swim depression, anxiety, and anhedonia along with changes in local dopamine/acetylcholine balance. Neuroscience (2012) 0.97
Morphine and naloxone, i.p. or locally, affect extracellular acetylcholine in the accumbens and prefrontal cortex. Pharmacol Biochem Behav (1996) 0.97
Systemic morphine simultaneously decreases extracellular acetylcholine and increases dopamine in the nucleus accumbens of freely moving rats. Neuropharmacology (1991) 0.95
Interleukin-1 beta decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats. Brain Res (1991) 0.95
Acetylcholine release in ventral tegmental area by hypothalamic self-stimulation, eating, and drinking. Pharmacol Biochem Behav (2000) 0.94
Feeding can enhance dopamine turnover in the prefrontal cortex. Brain Res Bull (1990) 0.94
Maternal hormonal manipulations in rats cause obesity and increase medial hypothalamic norepinephrine release in male offspring. Brain Res Dev Brain Res (1995) 0.94
Nucleus accumbens muscarinic receptors in the control of behavioral depression: antidepressant-like effects of local M1 antagonist in the Porsolt swim test. Neuroscience (2001) 0.93
Role of melanin-concentrating hormone in the control of ethanol consumption: Region-specific effects revealed by expression and injection studies. Physiol Behav (2010) 0.92
Plasticity of quantal size in ventral midbrain dopamine neurons: possible implications for the neurochemistry of feeding and reward. Appetite (1998) 0.91
Aversion to lateral hypothalamic stimulation caused by intragastric feeding or obesity. J Comp Physiol Psychol (1969) 0.89
Neurotensin self-injection in the ventral tegmental area. Brain Res (1987) 0.89
Glutamate release in the nucleus accumbens is involved in behavioral depression during the PORSOLT swim test. Neuroscience (2003) 0.89
Simultaneous microdialysis and amphetamine infusion in the nucleus accumbens and striatum of freely moving rats: increase in extracellular dopamine and serotonin. Brain Res Bull (1987) 0.88
Weight regulation in normal and hypothalamic hyperphagic rats. J Comp Physiol Psychol (1966) 0.88
Effects of superoxide anions on endothelial Ca2+ signaling pathways. Arterioscler Thromb Vasc Biol (1998) 0.87
Feeding: neural control of intake. Annu Rev Physiol (1971) 0.87
Neurotensin: a new 'reward peptide'. Brain Res (1984) 0.86
Hypothalamic infusion of amphetamine increases serotonin, dopamine and norepinephrine. Physiol Behav (1988) 0.86
Norepinephrine microinjections in the hypothalamic paraventricular nucleus increase extracellular dopamine and decrease acetylcholine in the nucleus accumbens: relevance to feeding reinforcement. J Neurochem (1997) 0.86
Feeding induced by opiates injected into the paraventricular hypothalamus. Peptides (1983) 0.85
Supraadditive effect of d-fenfluramine plus phentermine on extracellular acetylcholine in the nucleus accumbens: possible mechanism for inhibition of excessive feeding and drug abuse. Pharmacol Biochem Behav (2000) 0.85
Microdialysis evidence that acetylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine. Brain Res (1991) 0.85
"Copulation-reward site" in the posterior hypothalamus. Science (1966) 0.84
Overeating and obesity from damage to a noradrenergic system in the brain. Science (1973) 0.83
Mechanisms of L-NG nitroarginine/indomethacin-resistant relaxation in bovine and porcine coronary arteries. Br J Pharmacol (1996) 0.83
Feeding increases extracellular serotonin in the lateral hypothalamus of the rat as measured by microdialysis. Brain Res (1989) 0.82
Rats self-inject a dopamine antagonist in the lateral hypothalamus where it acts to increase extracellular dopamine in the nucleus accumbens. Pharmacol Biochem Behav (1995) 0.82
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: I. Inhibition by serotonin. Brain Res (1993) 0.82
Hypothalamic self-stimulation and stimulation escape in relation to feeding and mating. Fed Proc (1979) 0.82
Serotonin release in lateral and medial hypothalamus during feeding and its anticipation. Brain Res Bull (1990) 0.82
Systemic and local cocaine increase extracellular serotonin in the nucleus accumbens. Pharmacol Biochem Behav (1996) 0.81
A remote insertion technique for intracerebral microinjections in freely moving animals. J Neurosci Methods (1993) 0.81
Aversive hypothalamic stimulation releases acetylcholine in the nucleus accumbens, and stimulation-escape decreases it. Brain Res (2001) 0.80
Neurotensin: effects of hypothalamic and intravenous injections on eating and drinking in rats. Peptides (1984) 0.80
Endogenous opiate reward induced by an enkephalinase inhibitor, thiorphan, injected into the ventral midbrain. Behav Neurosci (1984) 0.79
Patterns of extracellular norepinephrine in the paraventricular hypothalamus: relationship to circadian rhythm and deprivation-induced eating behavior. Life Sci (1989) 0.79
Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion. Psychopharmacology (Berl) (1991) 0.79
Effects of feeding and insulin on extracellular acetylcholine in the amygdala of freely moving rats. Brain Res (1998) 0.78
Patterns of extracellular 5-hydroxyindoleacetic acid (5-HIAA) in the paraventricular hypothalamus (PVN): relation to circadian rhythm and deprivation-induced eating behavior. Pharmacol Biochem Behav (1989) 0.78
Hypothalamic Lesions by Electrocauterization: Disinhibition of Feeding and Self-Stimulation. Science (1965) 0.78
Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis. Brain Res Bull (1989) 0.78
Hypothalamic serotonin in treatments for feeding disorders and depression as studied by brain microdialysis. J Clin Psychiatry (1991) 0.78
Fenfluramine administered systemically or locally increases extracellular serotonin in the lateral hypothalamus as measured by microdialysis. Brain Res (1989) 0.78
Hyperphagia following intraventricular p-chlorophenylalanine-, leucine- or tryptophan-methyl esters: lack of correlation with whole brain serotonin levels. Pharmacol Biochem Behav (1979) 0.78
Effects of conditioned taste aversion on extracellular serotonin in the lateral hypothalamus and hippocampus of freely moving rats. Brain Res (1991) 0.78
Dopamine release in the nucleus accumbens by hypothalamic stimulation-escape behavior. Brain Res (1998) 0.78
Inhibition and disinhibition of self-stimulation and feeding: hypothalamic control and postingestional factors. J Comp Physiol Psychol (1968) 0.78
Galanin and alcohol dependence: neurobehavioral research. Neuropeptides (2005) 0.78
Hupothalamic hyperphagia: dissociation from hyperphagia following destruction of noradrenergic neurons. Science (1975) 0.78
Chronic clozapine selectively decreases prefrontal cortex dopamine as shown by simultaneous cortical, accumbens, and striatal microdialysis in freely moving rats. Pharmacol Biochem Behav (1995) 0.78
Neurotransmitters in the control of feeding and its rewards: monoamines, opiates, and brain-gut peptides. Res Publ Assoc Res Nerv Ment Dis (1984) 0.77
Phencyclidine (PCP) injected in the nucleus accumbens increases extracellular dopamine and serotonin as measured by microdialysis. Life Sci (1988) 0.77
Pharmacologic control of feeding. Annu Rev Pharmacol Toxicol (1977) 0.77
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: II. Inhibition by gamma-aminobutyric acid. Brain Res (1993) 0.77
Brain monoamines in the modulation of self-stimulation, feeding, and body weight. Res Publ Assoc Res Nerv Ment Dis (1981) 0.77
Influence of p-chloroamphetamine on female sexual reflexes and brain monoamine levels. Brain Res (1977) 0.77
The appetite suppressant, d-fenfluramine, decreases self-stimulation at a feeding site in the lateral hypothalamus. Pharmacol Biochem Behav (1989) 0.77
Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions. Eur J Pharmacol (1997) 0.76
Sulpiride injections in the lateral hypothalamus induce feeding and drinking in rats. Pharmacol Biochem Behav (1988) 0.76
Suppression of norepinephrine-elicited feeding by neurotensin: evidence for behavioral, anatomical and pharmacological specificity. Brain Res (1985) 0.76
Diminished amphetamine anorexia and enhanced fenfluramine anorexia after midbrain 6-hydroxydopamine. Psychopharmacology (Berl) (1984) 0.76
Physiological control of hypothalamically elicited feeding and drinking. J Comp Physiol Psychol (1970) 0.76
Increased tilt-cage activity after serotonin depletion by 5,7-dihydroxytryptamine. Neuropharmacology (1978) 0.76
Amphetamine-induced overeating and overweight in rats. Life Sci (1981) 0.76
Chronic lithium administration enhances serotonin release in the lateral hypothalamus but not in the hippocampus in rats. A microdialysis study. J Neural Transm Gen Sect (1990) 0.76
Dopamine in the lateral hypothalamus may be involved in the inhibition of locomotion related to food and water seeking. Brain Res Bull (1990) 0.76
Overeating after midbrain 6-hydroxydopamine: prevention by central injection of selective catecholamine reuptake blockers. Brain Res (1982) 0.76