Published in J Neurochem on August 01, 1999
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog Neurobiol (2006) 3.17
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. J Biol Chem (2001) 1.90
Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr Drug Targets (2006) 1.78
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem (2003) 1.56
Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder. Pharmacol Rev (2013) 1.52
Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling. Mol Cell Biol (2003) 1.41
Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders. Pharmacol Ther (2010) 1.39
HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse. J Neurochem (2006) 1.31
HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs. J Biol Chem (2011) 1.28
Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons. Am J Pathol (2010) 1.25
Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway. Mol Cell Biol (2002) 1.22
Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol (2008) 1.18
IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. J Immunol (2011) 1.18
Molecular targets of opiate drug abuse in neuroAIDS. Neurotox Res (2005) 1.16
Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine. Am J Pathol (2011) 1.15
GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals. Neurobiol Dis (2008) 1.10
Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis. J Proteome Res (2010) 1.08
Histone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes. J Neuroimmune Pharmacol (2010) 1.08
Opiate drug use and the pathophysiology of neuroAIDS. Curr HIV Res (2012) 1.07
Molecular pathology of neuro-AIDS (CNS-HIV). Int J Mol Sci (2009) 1.04
Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment. J Neurovirol (2009) 1.02
Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax. J Neurosci (2010) 1.01
GSK3beta in ethanol neurotoxicity. Mol Neurobiol (2009) 1.01
Effects of valproic acid coadministration on plasma efavirenz and lopinavir concentrations in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother (2004) 0.97
M- and T-tropic HIVs promote apoptosis in rat neurons. J Neuroimmune Pharmacol (2008) 0.96
Autophagy in dementias. Brain Pathol (2012) 0.95
HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1. J Gene Med (2006) 0.93
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS Res Ther (2010) 0.92
Role of β-catenin/TCF-4 signaling in HIV replication and pathogenesis: insights to informing novel anti-HIV molecular therapeutics. J Neuroimmune Pharmacol (2011) 0.92
Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS. J Neurovirol (2008) 0.91
Antiplatelet activity of valproic acid contributes to decreased soluble CD40 ligand production in HIV type 1-infected individuals. J Immunol (2010) 0.90
Interplay between Wnt/β-catenin signaling and HIV: virologic and biologic consequences in the CNS. J Neuroimmune Pharmacol (2012) 0.89
Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology (2011) 0.88
HIV-1 Tat inhibits NGF-induced Egr-1 transcriptional activity and consequent p35 expression in neural cells. J Cell Physiol (2008) 0.88
Involvement of the p53 and p73 transcription factors in neuroAIDS. Cell Cycle (2008) 0.87
Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction. J Cereb Blood Flow Metab (2014) 0.87
Suppression of immunodeficiency virus-associated neural damage by the p75 neurotrophin receptor ligand, LM11A-31, in an in vitro feline model. J Neuroimmune Pharmacol (2011) 0.84
Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: implications for synaptic dysfunction and neuronal damage. Biochim Biophys Acta (2013) 0.84
Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction. Mol Ther (2012) 0.84
Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders. J Neuroimmune Pharmacol (2014) 0.84
Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice. Eur J Pharmacol (2012) 0.83
Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS. J Neuroinflammation (2011) 0.83
Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury. Int J Clin Exp Pathol (2013) 0.83
Mitogen-activated protein kinase p38 in HIV infection and associated brain injury. J Neuroimmune Pharmacol (2011) 0.83
Biological targets for isatin and its analogues: Implications for therapy. Biologics (2007) 0.82
Morphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neurites. PLoS One (2014) 0.80
Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol (2015) 0.80
Evaluation of acute antiapoptotic effects of Li+ in neuronal cell cultures. J Neural Transm (Vienna) (2006) 0.80
Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. Curr HIV Res (2015) 0.79
The ART of HIV therapies: dopaminergic deficits and future treatments for HIV pediatric encephalopathy. Expert Rev Anti Infect Ther (2009) 0.79
Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication. J Virol (2013) 0.79
Glycogen synthase kinase-3beta (GSK-3beta) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons. J Neurovirol (2009) 0.79
Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. Br J Pharmacol (2014) 0.78
HIV-1 Tat-Mediated Calcium Dysregulation and Neuronal Dysfunction in Vulnerable Brain Regions. Curr Drug Targets (2015) 0.78
GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity. Mol Cell Neurosci (2015) 0.77
The role of tau protein in HIV-associated neurocognitive disorders. Mol Neurodegener (2014) 0.76
Chronic lithium feeding reduces upregulated brain arachidonic acid metabolism in HIV-1 transgenic rat. J Neuroimmune Pharmacol (2012) 0.75
Oligodendrocyte Injury and Pathogenesis of HIV-1-Associated Neurocognitive Disorders. Brain Sci (2016) 0.75
Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells. Acta Pharmacol Sin (2013) 0.75
Are Structural Changes Induced by Lithium in the HIV Brain Accompanied by Changes in Functional Connectivity? PLoS One (2015) 0.75
Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. N Engl J Med (1994) 2.84
Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature (1998) 2.69
Enhancer element at the 3'-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene. J Biol Chem (1991) 2.55
Yield and impact of emergency capsule enteroscopy in severe obscure-overt gastrointestinal bleeding. Endoscopy (2012) 2.52
Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease. J Exp Med (1992) 2.48
Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A. J Virol (1999) 2.42
Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual. J Virol (1988) 2.24
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Res (1999) 2.02
Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. J Neuroimmunol (1999) 1.76
An open prospective randomised trial to reduce the pain of blood glucose testing: ear versus thumb. BMJ (2000) 1.61
Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine. J Clin Microbiol (1995) 1.57
Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A. Clin Infect Dis (1998) 1.55
Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy. J Neurovirol (1995) 1.52
Rectal administration of metronidazole provides therapeutic plasma levels in postoperative patients. N Engl J Med (1981) 1.45
U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture. Proc Natl Acad Sci U S A (1998) 1.39
Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. J Immunol (2000) 1.38
Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro. Biochem Biophys Res Commun (1999) 1.36
Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons. J Neurosci (1998) 1.33
Emergency intubation for acutely ill and injured patients. Cochrane Database Syst Rev (2008) 1.31
Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. J Biol Chem (1996) 1.27
Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis (1994) 1.24
Seasonal mood disorders. Patterns of seasonal recurrence in mania and depression. Arch Gen Psychiatry (1993) 1.24
Comparison of cell cycle arrest, transactivation, and apoptosis induced by the simian immunodeficiency virus SIVagm and human immunodeficiency virus type 1 vpr genes. J Virol (2001) 1.21
HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism. J Biol Chem (1998) 1.20
Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV). FEBS Lett (1987) 1.19
Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice. Brain (2005) 1.16
Platelet-activating factor receptor activation. An initiator step in HIV-1 neuropathogenesis. J Biol Chem (1998) 1.16
Effects of zidovudine use during pregnancy on resistance and vertical transmission of human immunodeficiency virus type 1. Clin Infect Dis (1995) 1.16
Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Mol Cell Biol (1995) 1.14
Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini. J Virol (1994) 1.13
Human immunodeficiency virus type 1 Tat protein induces death by apoptosis in primary human neuron cultures. J Neurovirol (1997) 1.13
A rapid and sensitive assay for histone acetyl-transferase activity. Nucleic Acids Res (1998) 1.12
Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. Eur J Neurosci (2001) 1.06
HIV-1 infection of the developing nervous system: central role of astrocytes in pathogenesis. Virus Res (1994) 1.04
Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. J Neurochem (2001) 1.03
Antibodies to HTLV-III/LAV in Venezuelan patients with acute malarial infections. N Engl J Med (1986) 1.01
Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries. J Clin Endocrinol Metab (2000) 1.01
Distribution of glutamate transporter subtypes during human brain development. J Neurochem (1997) 1.01
Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity. J Virol (1995) 1.00
Human herpesvirus 6. Clin Infect Dis (2001) 0.99
Impact of a pharmacokinetics consultation service on clinical outcomes in an ambulatory-care epilepsy clinic. Am J Hosp Pharm (1988) 0.99
Detection of human herpesvirus 6 by reverse transcription-PCR. J Clin Microbiol (1999) 0.99
Functional identification and analysis of cis-acting sequences which mediate genome cleavage and packaging in human herpesvirus 6. J Virol (1998) 0.98
In vivo gene delivery and expression by bacteriophage lambda vectors. J Appl Microbiol (2007) 0.98
Testing for antibodies to AIDS-associated retrovirus (HTLV-III/LAV) by indirect fixed cell immunofluorescence: specificity, sensitivity, and applications. J Med Virol (1986) 0.97
Simultaneous in situ detection of apoptosis and necrosis in monolayer cultures by TUNEL and trypan blue staining. Biotechniques (1997) 0.96
Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. Neuropsychopharmacology (1993) 0.95
Retroviral etiology of the acquired immune deficiency syndrome (AIDS). AIDS Res (1986) 0.94
SIVsmm infection of macaque and mangabey monkeys: correlation between in vivo and in vitro properties of different isolates. Dev Biol Stand (1990) 0.93
In situ trypan blue staining of monolayer cell cultures for permanent fixation and mounting. Biotechniques (1997) 0.93
Increased prevalence of electrophysiological abnormalities in children with psychological, physical, and sexual abuse. J Neuropsychiatry Clin Neurosci (1993) 0.93
Outcome of patients with obscure gastrointestinal bleeding after negative capsule endoscopy: results of a one-year follow-up study. Gastroenterol Clin Biol (2010) 0.92
HIV-1-induced neuronal injury in the developing brain. J Leukoc Biol (1999) 0.92
Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis. Neuropathol Appl Neurobiol (1999) 0.91
Polypharmacy in an Australian teaching hospital. Preliminary analysis of prevalence, types of drugs and associations. Med J Aust (1986) 0.91
Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells. J Neurochem (2000) 0.91
Expression of the T4 molecule (AIDS virus receptor) by human brain-derived cells. FEBS Lett (1987) 0.90
Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virology (1996) 0.90
Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells. Cell Differ (1974) 0.90
Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14. Virology (1998) 0.89
ELAC2 polymorphisms and prostate cancer risk: a meta-analysis based on 18 case-control studies. Prostate Cancer Prostatic Dis (2010) 0.89
Identification and analysis of a novel heparin-binding glycoprotein encoded by human herpesvirus 7. J Virol (2000) 0.89
Mitogenic up-regulation of the PRL-1 protein-tyrosine phosphatase gene by Egr-1. Egr-1 activation is an early event in liver regeneration. J Biol Chem (1999) 0.89
Enhanced responsiveness to nuclear factor kappa B contributes to the unique phenotype of simian immunodeficiency virus variant SIVsmmPBj14. J Virol (1994) 0.89
The tyrosine-17 residue of Nef in SIVsmmPBj14 is required for acute pathogenesis and contributes to replication in macrophages. Virology (1998) 0.88
Prevalence of AIDS-associated retrovirus and antibodies among male homosexuals at risk for AIDS in Greenwich Village. AIDS Res (1986) 0.88
Neuropathogenesis of AIDS. Mol Med Today (1996) 0.88
In situ amplification and detection of HIV-1 DNA in fixed pediatric AIDS brain tissue. Hum Pathol (1996) 0.87
SIVsmmPBj14 induces expression of a mucosal integrin on macaque lymphocytes. Virology (1996) 0.87
Release of the neuronal glycoprotein ICAM-5 in serum after hypoxic-ischemic injury. Ann Neurol (2000) 0.87
Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14. J Virol (1998) 0.86
Audit and scientific management of drug use in an Australian teaching hospital. Aust Health Rev (1982) 0.86
Berberine attenuates doxorubicin-induced cardiotoxicity in mice. J Int Med Res (2011) 0.86
Rare AU-1-like G3P[9] human rotaviruses with a Kun-like NSP4 gene detected in children with diarrhea in Italy. J Clin Microbiol (2007) 0.85
Adjunctive therapies for HIV-1 associated neurologic disease. Neurotox Res (2005) 0.85
Meta-analysis confirms that a common G/C variant in the pre-miR-146a gene contributes to cancer susceptibility and that ethnicity, gender and smoking status are risk factors. Genet Mol Res (2012) 0.84
Endoscopic band ligation could decrease recurrent bleeding in Mallory-Weiss syndrome as compared to haemostasis by hemoclips plus epinephrine. Aliment Pharmacol Ther (2009) 0.84
Efficient gene transfer into human monocyte-derived macrophages using defective lentiviral vectors. Cell Mol Biol (Noisy-le-grand) (2003) 0.84
Prospective audit of an aminoglycoside consultative service in a general hospital. Med J Aust (1992) 0.83
Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis. Neuropathol Appl Neurobiol (1995) 0.83
Excitotoxicity and dopaminergic dysfunction in the acquired immunodeficiency syndrome dementia complex. Therapeutic implications. Arch Neurol (1991) 0.83
Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis. Neuropathol Appl Neurobiol (1997) 0.83
Halothane resistance in Drosophila melanogaster: development of a model and gene localization techniques. Anesth Analg (1996) 0.83
Successful substitution of rectal metronidazole administration for intravenous use. Lancet (1983) 0.83