Functional characterization and potential applications for enhanced green fluorescent protein- and epitope-fused human M1 muscarinic receptors.

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Published in J Neurochem on August 01, 1999

Authors

C Weill1, J L Galzi, S Chasserot-Golaz, M Goeldner, B Ilien

Author Affiliations

1: Laboratoire de Chimie Bio-Organique, UMR 7514 CNRS, Illkirch, France.

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New mutants to explore nicotinic receptor functions. Trends Pharmacol Sci (1992) 0.86

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Cysteine mutants as chemical sensors for ligand-receptor interactions. Trends Pharmacol Sci (2001) 0.86

Activation of Epstein-Barr virus promoters by a growth-factor and a glucocorticoid. FEBS Lett (1991) 0.86

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Cryophotolysis of ortho-nitrobenzyl derivatives of enzyme ligands for the potential kinetic crystallography of macromolecules. Chembiochem (2001) 0.82

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The acetylcholine receptor: a model of an allosteric membrane protein mediating intercellular communication. Ciba Found Symp (1992) 0.79

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Trp82 and Tyr332 are involved in two quaternary ammonium binding domains of human butyrylcholinesterase as revealed by photoaffinity labeling with [3H]DDF. Biochemistry (1998) 0.79

Chromogranin A induces a neurotoxic phenotype in brain microglial cells. J Biol Chem (1998) 0.79

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Photoactivatable opiate derivatives as irreversible probes of the mu-opioid receptor. J Med Chem (1990) 0.77

A photoaffinity probe for the polyamine site regulating the NMDA receptor. Eur J Pharmacol (1995) 0.77

Novel photoactivatable agonist of the nicotinic acetylcholine receptor of potential use for exploring the functional activated state. J Neurochem (1996) 0.77

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The acetylcholine receptor: functional architecture and regulation. Adv Second Messenger Phosphoprotein Res (1990) 0.77

Photochemical labeling of membrane-associated and channel-forming domains of proteins directed by energy transfer. FEBS Lett (1994) 0.77

Differentiation of solubilized dopamine receptors from spirodecanone binding sites in rat striatum. FEBS Lett (1980) 0.77

The hypophysis controls expression of SNAP-25 and other SNAREs in the adrenal gland. J Neurocytol (2002) 0.77

6-Coumarin diazonium salt: a specific affinity label of the Torpedo acetylcholinesterase peripheral site. Mol Pharmacol (1995) 0.76

2-Diazohistidinyl thyrotropin-releasing hormone (TRH): a photosensitive TRH analog. J Recept Res (1991) 0.76

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Trp279 is involved in the binding of quaternary ammonium at the peripheral site of Torpedo marmorata acetylcholinesterase. Eur J Biochem (1994) 0.75

Steroid metabolism in normal and transformed liver cells. Relation with glucocorticoid antagonism. Cancer Biochem Biophys (1985) 0.75

Insight in the exocytotic process in chromaffin cells: regulation by trimeric and monomeric G proteins. Biochimie (2000) 0.75

Antiproliferative action of the steroid RU486 in cultured human lymphoma cells. Cancer Lett (1993) 0.75

Regulation of acetylcholine receptor gene expression by neural factors and electrical activity during motor endplate formation. Biochem Soc Symp (1990) 0.75

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Binding studies of the antiglucocorticoid RU38486 in Daudi and Raji lymphoma cells. J Steroid Biochem (1989) 0.75

Pharmacological and structural integrity of muscarinic M2 acetylcholine receptors produced in Sf9 insect cells. Eur J Pharmacol (1997) 0.75

Aryldiazonium salts as photoaffinity labels of the nicotinic acetylcholine receptor PCP binding site. FEBS Lett (1985) 0.75

Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor. J Med Chem (1987) 0.75

Non peptide photoaffinity probes of the mu-opioid receptor. Prog Clin Biol Res (1990) 0.75

An approach to the mechanism of the potent antiglucocorticoid: 17 beta-hydroxy-11 beta-4-dimethylaminophenyl-17 alpha-propynyl-estra-4,9-dien-3-one. J Steroid Biochem (1984) 0.75

[Bacterial toxins: useful for studying G-proteins implicated in the mechanism of exocytosis in neuroendocrine cells]. J Soc Biol (1999) 0.75

Metabolism and antiproliferative effect of the glucocorticoid antagonist RU38486 in cultured liver and hepatoma cells. J Steroid Biochem (1986) 0.75