Published in Front Neuroendocrinol on July 01, 1999
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia. Proc Natl Acad Sci U S A (2008) 3.21
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell (2008) 2.73
Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma. Neurology (2014) 2.67
The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2013) 2.27
Motivations and methods for analyzing pulsatile hormone secretion. Endocr Rev (2008) 2.01
Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors. Proc Natl Acad Sci U S A (2006) 1.52
Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth. J Clin Invest (2001) 1.51
Diagnosis and management of polycystic liver disease. Nat Rev Gastroenterol Hepatol (2013) 1.46
Cubilin and megalin in radiation-induced renal injury with labelled somatostatin analogues: are we just dealing with the kidney? Eur J Nucl Med Mol Imaging (2005) 1.44
The Treatment of Cushing's Disease. Endocr Rev (2015) 1.35
In situ maleimide bridging of disulfides and a new approach to protein PEGylation. Bioconjug Chem (2011) 1.33
The role of G protein-coupled receptors in the pathology of Alzheimer's disease. Nat Rev Neurosci (2011) 1.30
Treatment of malignant pheochromocytoma. Horm Metab Res (2009) 1.25
Acromegaly. Endocrinol Metab Clin North Am (2008) 1.23
Neuronostatin encoded by the somatostatin gene regulates neuronal, cardiovascular, and metabolic functions. J Biol Chem (2008) 1.19
Neuronal ciliary signaling in homeostasis and disease. Cell Mol Life Sci (2010) 1.17
Regulation of electroneutral NaCl absorption by the small intestine. Annu Rev Physiol (2011) 1.15
99mTc-EDDA/HYNIC-octreotate scintigraphy, an efficient method for the detection and staging of carcinoid tumours: results of 3 years' experience. Eur J Nucl Med Mol Imaging (2006) 1.13
Prospective evaluation of ⁶⁸Ga-DOTA-NOC PET-CT in phaeochromocytoma and paraganglioma: preliminary results from a single centre study. Eur Radiol (2011) 1.10
Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2009) 1.10
Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma. Gut (2004) 1.10
Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies. Gut (2002) 1.08
Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion. Nat Med (2015) 1.07
Activation of brain somatostatin 2 receptors stimulates feeding in mice: analysis of food intake microstructure. Physiol Behav (2010) 1.06
Pituitary somatostatin receptor signaling. Trends Endocrinol Metab (2010) 1.03
Clinical applications of Gallium-68. Appl Radiat Isot (2013) 1.02
Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target? Front Pharmacol (2013) 1.02
δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling. PLoS One (2014) 0.98
Central injection of the stable somatostatin analog ODT8-SST induces a somatostatin2 receptor-mediated orexigenic effect: role of neuropeptide Y and opioid signaling pathways in rats. Endocrinology (2010) 0.97
Oestrogen-mediated regulation of somatostatin receptor expression in human breast cancer cell lines assessed with 99mTc-depreotide. Eur J Nucl Med Mol Imaging (2004) 0.96
Neuronostatin inhibits cardiac contractile function via a protein kinase A- and JNK-dependent mechanism in murine hearts. Am J Physiol Regul Integr Comp Physiol (2009) 0.95
Peptide receptor radionuclide therapy using radiolabeled somatostatin analogs: focus on future developments. Clin Transl Imaging (2014) 0.95
PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms. Theranostics (2014) 0.95
Selective central activation of somatostatin receptor 2 increases food intake, grooming behavior and rectal temperature in rats. J Physiol Pharmacol (2010) 0.94
Current imaging strategies in rheumatoid arthritis. Am J Nucl Med Mol Imaging (2012) 0.94
Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes. Cell Rep (2013) 0.93
Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines. Cancer (2008) 0.93
Expression of Somatostatin Receptor (SSTR) Subtypes (SSTR-1, 2A, 3, 4 and 5) in Neuroendocrine Tumors Using Real-time RT-PCR Method and Immunohistochemistry. Acta Histochem Cytochem (2012) 0.93
Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics. Oncologist (2012) 0.92
Somatostatin agonists for treatment of acromegaly. Mol Cell Endocrinol (2007) 0.92
Somatostatin stimulates intestinal NHE8 expression via p38 MAPK pathway. Am J Physiol Cell Physiol (2010) 0.92
Neuropeptide receptors as potential drug targets in the treatment of inflammatory conditions. Br J Clin Pharmacol (2014) 0.91
Radio-guided surgery with the use of [99mTc-EDDA/HYNIC]octreotate in intra-operative detection of neuroendocrine tumours of the gastrointestinal tract. Eur J Nucl Med Mol Imaging (2007) 0.91
Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab (2012) 0.91
Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. J Med Chem (2009) 0.91
Beta(2)/beta(3)-di- and alpha/beta(3)-tetrapeptide derivatives as potent agonists at somatostatin sst(4) receptors. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.91
Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse model. Mol Endocrinol (2010) 0.91
Glucagon secretion and signaling in the development of diabetes. Front Physiol (2012) 0.90
68Ga-DOTATOC PET/CT and somatostatin receptor (sst1-sst5) expression in normal human tissue: correlation of sst2 mRNA and SUVmax. Eur J Nucl Med Mol Imaging (2011) 0.90
Effect of acupuncture at Foot-Yangming Meridian on gastric mucosal blood flow, gastric motility and brain-gut peptide. World J Gastroenterol (2007) 0.89
Somatostatin and somatostatin receptor gene expression in dominant and subordinate males of an African cichlid fish. Behav Brain Res (2007) 0.89
Somatostatin receptor type 2 mediates bombesin-induced inhibition of gastric acid secretion in mice. J Physiol (2003) 0.89
Somatostatin stimulates menin gene expression by inhibiting protein kinase A. Am J Physiol Gastrointest Liver Physiol (2008) 0.89
Somatostatin and its receptors contribute in a tissue-specific manner to the sex-dependent metabolic (fed/fasting) control of growth hormone axis in mice. Am J Physiol Endocrinol Metab (2010) 0.88
Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas. BMC Endocr Disord (2010) 0.88
Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever. Antiviral Res (2011) 0.88
Mechanisms of action and resistance of somatostatin analogues for the treatment of hepatocellular carcinoma: a message not well taken. Dig Dis Sci (2008) 0.88
Mechanisms underlying modulation of monocarboxylate transporter 1 (MCT1) by somatostatin in human intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2009) 0.87
The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function. World J Surg (2011) 0.87
Evaluation of differentially expressed genes identified in keratoconus. Mol Vis (2009) 0.87
Imaging in neuroendocrine tumors: an update for the clinician. Int J Endocr Oncol (2015) 0.87
Constitutive somatostatin receptor activity determines tonic pituitary cell response. Mol Endocrinol (2009) 0.86
Somatostatin receptor type 2 antagonism improves glucagon and corticosterone counterregulatory responses to hypoglycemia in streptozotocin-induced diabetic rats. Diabetes (2011) 0.86
Pattern of Fos expression in the brain induced by selective activation of somatostatin receptor 2 in rats. Brain Res (2010) 0.86
Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats. Neurogastroenterol Motil (2011) 0.86
Continuing pursuit for ideal systemic anticancer radiotherapeutics. Invest New Drugs (2011) 0.86
Peripheral PACAP inhibits gastric acid secretion through somatostatin release in mice. Br J Pharmacol (2004) 0.85
Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex. Front Neuroanat (2014) 0.85
Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies. Psychopharmacology (Berl) (2008) 0.85
64Cu-labeled somatostatin analogues conjugated with cross-bridged phosphonate-based chelators via strain-promoted click chemistry for PET imaging: in silico through in vivo studies. J Med Chem (2014) 0.84
Somatostatin inhibits potassium-evoked glutamate release by activation of the sst(2) somatostatin receptor in the mouse retina. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.84
Effects of octreotide and insulin on colon cancer cellular proliferation and correlation with hTERT activity. Oncoscience (2014) 0.84
Octreotide induces caspase activation and apoptosis in human hepatoma HepG2 cells. World J Gastroenterol (2011) 0.84
Colocalization of somatostatin receptors and epidermal growth factor receptors in breast cancer cells. Cancer Cell Int (2006) 0.84
Mapping of somatostatin receptor types in GH or/and PRL producing pituitary adenomas. J Clin Pathol (2006) 0.84
Effect of pasireotide on glucose- and growth hormone-related biomarkers in patients with inadequately controlled acromegaly. Endocrine (2016) 0.84
Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor. J Physiol (2007) 0.83
Tumoral prostate shows different expression pattern of somatostatin receptor 2 (SSTR2) and phosphotyrosine phosphatase SHP-1 (PTPN6) according to tumor progression. Adv Urol (2009) 0.83
Selective hepatic arterial infusion of In-111-DTPA-Phe1-octreotide in neuroendocrine liver metastases. Eur J Nucl Med Mol Imaging (2008) 0.83
A review of the use of somatostatin analogs in oncology. Onco Targets Ther (2013) 0.83
Differential regulation of somatostatin receptors 1 and 2 mRNA and protein expression by tamoxifen and estradiol in breast cancer cells. J Carcinog (2005) 0.83
Characterization of intracellular signaling mediated by human somatostatin receptor 5: role of the DRY motif and the third intracellular loop. Endocrinology (2009) 0.82
Promoter hypermethylation-related reduced somatostatin production promotes uncontrolled cell proliferation in colorectal cancer. PLoS One (2015) 0.82
Acupuncture for visceral pain: neural substrates and potential mechanisms. Evid Based Complement Alternat Med (2014) 0.82
Localisation of somatostatin and somatostatin receptors in benign and malignant ovarian tumours. Br J Cancer (2002) 0.82
The somatostatin analogue octreotide inhibits angiogenesis in the earliest, but not in advanced, stages of portal hypertension in rats. J Cell Mol Med (2008) 0.82
Established and potential therapeutic applications of octreotide in palliative care. Support Care Cancer (2008) 0.82
Prostaglandin E2 increases the expression of the neurokinin1 receptor in adult sensory neurones in culture: a novel role of prostaglandins. Br J Pharmacol (2003) 0.82
Tumor-associated macrophages in glioblastoma multiforme-a suitable target for somatostatin receptor-based imaging and therapy? PLoS One (2015) 0.82
Anxiolytic-like effects of somatostatin isoforms SST 14 and SST 28 in two animal models (Rattus norvegicus) after intra-amygdalar and intra-septal microinfusions. Psychopharmacology (Berl) (2011) 0.81
Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis). Endocrinology (2011) 0.81
Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice. Am J Physiol Gastrointest Liver Physiol (2011) 0.81
Axotomy-induced changes in the chemical coding pattern of colon projecting calbindin-positive neurons in the inferior mesenteric ganglia of the pig. J Mol Neurosci (2013) 0.81
Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells. J Exp Clin Cancer Res (2009) 0.81
Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer. Br J Cancer (2013) 0.81
The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth. PLoS One (2009) 0.81
Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5. Mol Endocrinol (2012) 0.81
Constitutive somatostatin receptor subtype-3 signaling suppresses growth hormone synthesis. Mol Endocrinol (2014) 0.80
Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse. PLoS One (2014) 0.80
The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III. Evid Based Complement Alternat Med (2011) 0.80