The Rev protein is able to transport to the cytoplasm small nucleolar RNAs containing a Rev binding element.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMC 1369823)

Published in RNA on August 01, 1999

Authors

S B Buonomo1, A Michienzi, F G De Angelis, I Bozzoni

Author Affiliations

1: Istituto Pasteur, Fondazione Cenci-Bolognetti, Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy.

Articles cited by this

CRM1 is an export receptor for leucine-rich nuclear export signals. Cell (1997) 18.60

Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell (1997) 10.71

Exportin 1 (Crm1p) is an essential nuclear export factor. Cell (1997) 10.32

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell (1995) 9.98

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA. Proc Natl Acad Sci U S A (1989) 8.76

Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell (1996) 7.92

Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function. Cell (1989) 7.46

The small nucleolar RNAs. Annu Rev Biochem (1995) 6.26

Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell (1997) 5.60

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA. Chem Biol (1997) 5.49

The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell (1996) 5.14

A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J (1989) 4.91

Sno storm in the nucleolus: new roles for myriad small RNPs. Cell (1997) 4.60

Function and synthesis of small nucleolar RNAs. Curr Opin Cell Biol (1997) 4.52

HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA. Cell (1991) 4.43

The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev (1997) 4.26

The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm. Genes Dev (1994) 3.34

Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs. J Mol Biol (1996) 3.19

In vitro assembly of U1 snRNPs. EMBO J (1987) 3.18

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway. EMBO J (1997) 3.10

Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis. Mol Cell Biol (1997) 2.95

Transport of macromolecules between the nucleus and the cytoplasm. RNA (1998) 2.63

The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization. EMBO J (1998) 2.61

An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs. EMBO J (1991) 2.38

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev. J Virol (1999) 2.37

Gamma-monomethyl phosphate: a cap structure in spliceosomal U6 small nuclear RNA. Proc Natl Acad Sci U S A (1989) 2.34

Processing of the intron-encoded U16 and U18 snoRNAs: the conserved C and D boxes control both the processing reaction and the stability of the mature snoRNA. EMBO J (1996) 2.31

Antisense snoRNAs: a family of nucleolar RNAs with long complementarities to rRNA. Trends Biochem Sci (1995) 2.29

The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence. Genes Dev (1992) 2.24

Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs. Proc Natl Acad Sci U S A (1991) 2.19

Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein. J Virol (1990) 2.17

A novel small nucleolar RNA (U16) is encoded inside a ribosomal protein intron and originates by processing of the pre-mRNA. EMBO J (1993) 2.07

Elements essential for processing intronic U14 snoRNA are located at the termini of the mature snoRNA sequence and include conserved nucleotide boxes C and D. RNA (1996) 2.04

A common maturation pathway for small nucleolar RNAs. EMBO J (1995) 2.02

Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proc Natl Acad Sci U S A (1992) 1.96

The roles of nucleolar structure and function in the subcellular location of the HIV-1 Rev protein. J Cell Sci (1995) 1.93

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses. Nucleic Acids Res (1990) 1.90

Accumulation of U14 small nuclear RNA in Saccharomyces cerevisiae requires box C, box D, and a 5', 3' terminal stem. Mol Cell Biol (1992) 1.80

Expression of small, therapeutic RNAs in human cell nuclei. Gene Ther (1997) 1.71

Conserved boxes C and D are essential nucleolar localization elements of U14 and U8 snoRNAs. EMBO J (1998) 1.67

The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators. Trends Biochem Sci (1991) 1.67

In vitro assembly of the mouse U14 snoRNP core complex and identification of a 65-kDa box C/D-binding protein. RNA (1998) 1.43

In vivo identification of nuclear factors interacting with the conserved elements of box C/D small nucleolar RNAs. Mol Cell Biol (1998) 1.34

The regulation of export of mRNA from nucleus to cytoplasm. Curr Opin Cell Biol (1993) 1.33

Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain. J Virol (1994) 1.22

Small RNA chaperones for ribosome biogenesis. Science (1995) 1.16

The mechanisms controlling ribosomal protein L1 pre-mRNA splicing are maintained in evolution and rely on conserved intron sequences. Nucleic Acids Res (1992) 1.11

Nucleolar localization elements in U8 snoRNA differ from sequences required for rRNA processing. RNA (1998) 1.09

Transduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture. J Virol (1996) 1.04

Site-specific phosphorylation of the human immunodeficiency virus type-1 Rev protein accelerates formation of an efficient RNA-binding conformation. Biochemistry (1997) 0.97

Localization of HIV-1 RNA in mammalian nuclei. J Cell Biol (1996) 0.95

Cytotoxic activity of rev protein of human immunodeficiency virus type 1 by nucleolar dysfunction. Exp Cell Res (1993) 0.91

Articles by these authors

Xenopus laevis ribosomal protein genes: isolation of recombinant cDNA clones and study of the genomic organization. Nucleic Acids Res (1981) 2.53

The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc Natl Acad Sci U S A (2007) 2.34

Processing of the intron-encoded U16 and U18 snoRNAs: the conserved C and D boxes control both the processing reaction and the stability of the mature snoRNA. EMBO J (1996) 2.31

Nucleotide sequences of cloned cDNA fragments specific for six Xenopus laevis ribosomal proteins. Gene (1982) 2.13

A novel small nucleolar RNA (U16) is encoded inside a ribosomal protein intron and originates by processing of the pre-mRNA. EMBO J (1993) 2.07

Expression of two Xenopus laevis ribosomal protein genes in injected frog oocytes. A specific splicing block interferes with the L1 RNA maturation. J Mol Biol (1984) 2.03

Expression of ribosomal-protein genes in Xenopus laevis development. Cell (1982) 1.96

Ribosomal protein production in normal and anucleolate Xenopus embryos: regulation at the posttranscriptional and translational levels. Cell (1985) 1.89

Nucleotide sequence of the L1 ribosomal protein gene of Xenopus laevis: remarkable sequence homology among introns. EMBO J (1985) 1.86

The ribosomal protein L2 in S. cerevisiae controls the level of accumulation of its own mRNA. EMBO J (1991) 1.62

Expression of ribosomal protein genes and regulation of ribosome biosynthesis in Xenopus development. Trends Biochem Sci (1989) 1.61

In vitro study of processing of the intron-encoded U16 small nucleolar RNA in Xenopus laevis. Mol Cell Biol (1994) 1.57

The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae. Mol Cell Biol (1990) 1.56

The accumulation of mature RNA for the Xenopus laevis ribosomal protein L1 is controlled at the level of splicing and turnover of the precursor RNA. EMBO J (1987) 1.51

Yeast snoRNA accumulation relies on a cleavage-dependent/polyadenylation-independent 3'-processing apparatus. EMBO J (2000) 1.47

Replication of ribosomal DNA in Xenopus laevis. Eur J Biochem (1981) 1.45

Identification of the sequences responsible for the splicing phenotype of the regulatory intron of the L1 ribosomal protein gene of Xenopus laevis. Mol Cell Biol (1992) 1.45

Sequences coding for the ribosomal protein L14 in Xenopus laevis and Xenopus tropicalis; homologies in the 5' untranslated region are shared with other r-protein mRNAs. Nucleic Acids Res (1986) 1.42

Two different snoRNAs are encoded in introns of amphibian and human L1 ribosomal protein genes. Nucleic Acids Res (1993) 1.39

Processing of the intron-encoded U18 small nucleolar RNA in the yeast Saccharomyces cerevisiae relies on both exo- and endonucleolytic activities. Mol Cell Biol (1998) 1.38

Ribosomal protein L2 in Saccharomyces cerevisiae is homologous to ribosomal protein L1 in Xenopus laevis. Isolation and characterization of the genes. J Biol Chem (1988) 1.38

In vivo identification of nuclear factors interacting with the conserved elements of box C/D small nucleolar RNAs. Mol Cell Biol (1998) 1.34

Isolation and structural analysis of ribosomal protein genes in Xenopus laevis. Homology between sequences present in the gene and in several different messenger RNAs. J Mol Biol (1982) 1.30

Splicing of Xenopus laevis ribosomal protein RNAs is inhibited in vivo by antisera to ribonucleoproteins containing U1 small nuclear RNA. J Mol Biol (1984) 1.23

Identification of the cis-elements mediating the autogenous control of ribosomal protein L2 mRNA stability in yeast. EMBO J (1995) 1.22

A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells. Leukemia (2009) 1.21

Characterization of histone genes isolated from Xenopus laevis and Xenopus tropicalis genomic libraries. Nucleic Acids Res (1982) 1.18

Construction of a recombinant bacterial plasmid containing DNA sequences for a mouse embryonic globin chain. Nucleic Acids Res (1979) 1.17

Gene dosage alteration of L2 ribosomal protein genes in Saccharomyces cerevisiae: effects on ribosome synthesis. Mol Cell Biol (1988) 1.13

Release of U18 snoRNA from its host intron requires interaction of Nop1p with the Rnt1p endonuclease. EMBO J (2001) 1.11

Inefficient in vitro splicing of the regulatory intron of the L1 ribosomal protein gene of X.laevis depends on suboptimal splice site sequences. Biochem Biophys Res Commun (1992) 1.11

The mechanisms controlling ribosomal protein L1 pre-mRNA splicing are maintained in evolution and rely on conserved intron sequences. Nucleic Acids Res (1992) 1.11

Expression of the gene for ribosomal protein L1 in Xenopus embryos: alteration of gene dosage by microinjection. Genes Dev (1988) 1.05

Fibrillarin binds directly and specifically to U16 box C/D snoRNA. RNA (2000) 1.04

Identification of a novel element required for processing of intron-encoded box C/D small nucleolar RNAs in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.04

Epstein-Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29b. Oncogene (2009) 0.98

The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells. Cell Death Dis (2012) 0.97

A novel Mn++-dependent ribonuclease that functions in U16 SnoRNA processing in X. laevis. Biochem Biophys Res Commun (1997) 0.94

Emerging role for microRNAs in acute promyelocytic leukemia. Curr Top Microbiol Immunol (2007) 0.91

Complementarity of conserved sequence elements present in 28S ribosomal RNA and in ribosomal protein genes of Xenopus laevis and Xenopus tropicalis. Gene (1986) 0.89

Inhibition of human immunodeficiency virus type 1 replication by nuclear chimeric anti-HIV ribozymes in a human T lymphoblastoid cell line. Hum Gene Ther (1998) 0.89

RNA-protein interactions in the nuclei of Xenopus oocytes: complex formation and processing activity on the regulatory intron of ribosomal protein gene L1. Mol Cell Biol (1994) 0.89

U1 small nuclear RNA chimeric ribozymes with substrate specificity for the Rev pre-mRNA of human immunodeficiency virus. Proc Natl Acad Sci U S A (1996) 0.87

Ribosomal-protein synthesis is not autogenously regulated at the translational level in Xenopus laevis. Dev Biol (1985) 0.86

MicroRNAs and hematopoietic differentiation. Cold Spring Harb Symp Quant Biol (2006) 0.85

Intracellular ribozyme applications. Biochem Soc Trans (2002) 0.83

Self-cleaving motifs are found in close proximity to the sites utilized for U16 snoRNA processing. Gene (1995) 0.82

Use of adenoviral VAI small RNA as a carrier for cytoplasmic delivery of ribozymes. RNA (1997) 0.81

Clustered and interspersed repetitive DNA sequences in four amphibian species with different genome size. Biochim Biophys Acta (1978) 0.80

The primary sequence of the Schizosaccharomyces pombe protein homologous to S.cerevisiae ribosomal protein L2. Nucleic Acids Res (1993) 0.80

p62, a novel Xenopus laevis component of box C/D snoRNPs. RNA (2000) 0.79

U86, a novel snoRNA with an unprecedented gene organization in yeast. Biochem Biophys Res Commun (2001) 0.78

Splicing control of the L1 ribosomal protein gene of X.laevis: structural similarities between sequences present in the regulatory intron and in the 28S ribosomal RNA. Mol Biol Rep (1990) 0.75

Biosynthesis of U16 snoRNA in early development of X. laevis. Biochem Biophys Res Commun (1997) 0.75