Published in Oncogene on August 19, 1999
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Mol Cell Biol (2003) 1.72
NF-kappa B-mediated adaptive resistance to ionizing radiation. Free Radic Biol Med (2007) 1.58
Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling. J Biol Chem (2008) 1.30
ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model. Br J Cancer (2002) 1.18
CHK1 inhibitors in combination chemotherapy: thinking beyond the cell cycle. Mol Interv (2011) 1.14
Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor. Am J Pathol (2004) 1.11
ATM-NF-kappaB connection as a target for tumor radiosensitization. Curr Cancer Drug Targets (2007) 1.06
Crosstalk between ERK, AKT, and cell survival. Cancer Biol Ther (2014) 1.06
Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells. Mol Biol Cell (2002) 1.06
Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation. Stem Cells (2009) 1.01
Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Mol Biol Cell (2001) 1.00
Role and expression of FRS2 and FRS3 in prostate cancer. BMC Cancer (2011) 0.89
Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling. Am J Pathol (2010) 0.89
Targeted therapy against EGFR and VEGFR using ZD6474 enhances the therapeutic potential of UV-B phototherapy in breast cancer cells. Mol Cancer (2013) 0.82
New role for nuclear hormone receptors and coactivators in regulation of BRCA1-mediated DNA repair in breast cancer cell lines. Breast Cancer Res (2005) 0.81
Effect of nitric oxide donor and gamma irradiation on modifications of ERK and JNK in murine peritoneal macrophages. J Cell Commun Signal (2008) 0.75
Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate. Science (1993) 4.61
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway. J Biol Chem (2001) 2.37
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene (1997) 1.98
Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen. Cancer Res (2001) 1.98
Medical staffing in Ontario neonatal intensive care units. CMAJ (1989) 1.97
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro. EMBO J (1994) 1.95
Differentiation therapy of human cancer: basic science and clinical applications. Pharmacol Ther (2001) 1.71
Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biol Ther (2008) 1.61
Ordered phosphorylation of p42mapk by MAP kinase kinase. FEBS Lett (1992) 1.57
Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation. Mol Cell Biol (1996) 1.55
Autocrine loops with positive feedback enable context-dependent cell signaling. Am J Physiol Cell Physiol (2002) 1.55
Neutrophil plasma membranes. I. High-yield purification of human neutrophil plasma membrane vesicles by nitrogen cavitation and differential centrifugation. J Cell Biol (1980) 1.52
Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization. J Natl Cancer Inst (2001) 1.52
A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells. Proc Natl Acad Sci U S A (2001) 1.52
Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2. Mol Cell Biol (1993) 1.48
Identification, physical map location and sequence of the denV gene from bacteriophage T4. Nucleic Acids Res (1984) 1.46
Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation. Biochem J (1993) 1.45
The tumor volume and clonogen number relationship: tumor control predictions based upon tumor volume estimates derived from computed tomography. Int J Radiat Oncol Biol Phys (1995) 1.40
Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells. Cancer Res (2001) 1.38
Signal transduction and cellular radiation responses. Radiat Res (2000) 1.32
Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells. J Biol Chem (2001) 1.27
Evaluation of the precision of dimensional measurements of the mandible on panoramic radiographs. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (1998) 1.25
Activation of Raf by ionizing radiation. Nature (1996) 1.22
Genetic complementation of UV-induced DNA repair in Chinese hamster ovary cells by the denV gene of phage T4. Proc Natl Acad Sci U S A (1985) 1.21
Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells. Leukemia (2005) 1.21
The influence of quantitative tumor volume measurements on local control in advanced head and neck cancer using concomitant boost accelerated superfractionated irradiation. Int J Radiat Oncol Biol Phys (1995) 1.18
Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes. Mol Cell Biol (1997) 1.17
A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes. Mol Biol Cell (2000) 1.16
Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy. Cell Death Differ (2010) 1.16
Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation. Mol Biol Cell (2001) 1.16
Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver. Biochem J (1998) 1.16
Expression of a cloned denV gene of bacteriophage T4 in Escherichia coli. Proc Natl Acad Sci U S A (1985) 1.13
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells. Cancer Gene Ther (2010) 1.13
Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine. Mol Pharmacol (1997) 1.13
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways. Oncogene (2001) 1.10
Prevalent vertebral fractures among children initiating glucocorticoid therapy for the treatment of rheumatic disorders. Arthritis Care Res (Hoboken) (2010) 1.10
The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes. Mol Biol Cell (1998) 1.09
The effect of setup uncertainty on normal tissue sparing with IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys (2001) 1.08
Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation. Mol Cell Biol (1994) 1.08
Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells. Oncogene (1998) 1.06
Activation of tat-defective human immunodeficiency virus by ultraviolet light. New Biol (1990) 1.06
PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells. Nucleic Acids Res (2001) 1.05
A cancer terminator virus eradicates both primary and distant human melanomas. Cancer Gene Ther (2008) 1.05
The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells. Oncogene (2001) 1.04
Molecular mechanisms of radiation-induced accelerated repopulation. Radiat Oncol Investig (1999) 1.04
Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases. Int J Radiat Oncol Biol Phys (2000) 1.03
Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression. Hepatology (2001) 1.03
Photoactivated cross-linking of proteins within the erythrocyte membrane core. J Biol Chem (1976) 1.02
Distinctive gene expression profiles associated with Hepatitis B virus x protein. Oncogene (2001) 1.00
Radiosensitization of malignant glioma cells through overexpression of dominant-negative epidermal growth factor receptor. Clin Cancer Res (2001) 1.00
Calcium transport of Plasmodium chabaudi-infected erythrocytes. J Cell Biol (1982) 1.00
Comparison of adenylate cyclase and cAMP-dependent protein kinase in gametocytogenic and nongametocytogenic clones of Plasmodium falciparum. J Parasitol (1991) 1.00
Regulation of mda-7 gene expression during human melanoma differentiation. Oncogene (2000) 0.99
Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice. Biochem J (1998) 0.98
Targetting of protein phosphatase 1 to the sarcoplasmic reticulum of rabbit skeletal muscle by a protein that is very similar or identical to the G subunit that directs the enzyme to glycogen. Eur J Biochem (1990) 0.98
Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase. J Biol Chem (1995) 0.97
Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells. Radiat Res (1996) 0.97
Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway. Mol Cell Biol (1997) 0.97
Membrane potential of Plasmodium-infected erythrocytes. J Cell Biol (1982) 0.97
AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation. J Cell Physiol (2000) 0.95
Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling. Mol Pharmacol (1998) 0.95
Activation of Ras/Raf protects cells from melanoma differentiation-associated gene-5-induced apoptosis. Cell Death Differ (2006) 0.94
A truncated human xeroderma pigmentosum complementation group A protein expressed from an adenovirus sensitizes human tumor cells to ultraviolet light and cisplatin. Cancer Res (2001) 0.94
Factors determining outcome for breast-conserving irradiation with margin-directed dose escalation to the tumor bed. Int J Radiat Oncol Biol Phys (1998) 0.93
The inducible expression of dominant-negative epidermal growth factor receptor-CD533 results in radiosensitization of human mammary carcinoma cells. Clin Cancer Res (1999) 0.93
High affinity calcium binding sites on erythrocyte membrane proteins. Use of lanthanides as fluorescent probes. Biochim Biophys Acta (1974) 0.93
The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183. Mol Biol Cell (1994) 0.91
Membrane potential of erythrocytic stages of Plasmodium chabaudi free of the host cell membrane. Mol Biochem Parasitol (1986) 0.91
Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis. Am J Physiol Gastrointest Liver Physiol (2001) 0.91