O M Conneely

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev 1995 7.16
2 Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A 1998 2.76
3 Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science 2000 2.57
4 Dopaminergic and ligand-independent activation of steroid hormone receptors. Science 1991 2.33
5 Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol 1992 2.11
6 Dopamine activation of an orphan of the steroid receptor superfamily. Science 1991 1.78
7 Reproductive phenotpes of the progesterone receptor null mutant mouse. J Steroid Biochem Mol Biol 1996 1.55
8 Multifunctional roles of lactoferrin: a critical overview. Cell Mol Life Sci 2005 1.48
9 Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod 1998 1.44
10 Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology 1997 1.44
11 Structure of the chromosomal chicken progesterone receptor gene. Proc Natl Acad Sci U S A 1987 1.42
12 p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A 2001 1.35
13 Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis 1998 1.31
14 Molecular cloning of the chicken progesterone receptor. Science 1986 1.30
15 Orphan receptors: in search of a unifying hypothesis for activation. Mol Endocrinol 1992 1.30
16 Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone. Proc Natl Acad Sci U S A 1993 1.30
17 Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biol Reprod 1999 1.26
18 Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology 1997 1.26
19 Molecular cloning of the chicken avidin cDNA. Nucleic Acids Res 1987 1.25
20 Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc Natl Acad Sci U S A 1999 1.24
21 Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. J Neurochem 1999 1.21
22 A system for production of commercial quantities of human lactoferrin: a broad spectrum natural antibiotic. Biotechnology (N Y) 1995 1.21
23 Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors. Mol Endocrinol 1997 1.15
24 Involvement of the nuclear orphan receptor NURR1 in the regulation of corticotropin-releasing hormone expression and actions in human inflammatory arthritis. Arthritis Rheum 2001 1.09
25 Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Exp Neurol 1999 1.09
26 Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system. J Mol Neurosci 1996 1.07
27 Amino acid sequence of a chicken heat shock protein derived from the complementary DNA nucleotide sequence. Biochemistry 1986 1.06
28 Differential regulation of transcription by the NURR1/NUR77 subfamily of nuclear transcription factors. Gene Expr 1996 1.03
29 An alternative ligand-independent pathway for activation of steroid receptors. Recent Prog Horm Res 1995 1.00
30 Differential modes of activation define orphan subclasses within the steroid/thyroid receptor superfamily. Gene Expr 1992 1.00
31 Mutational analysis of the chicken progesterone receptor. J Biol Chem 1989 1.00
32 Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. J Endocrinol 2001 0.99
33 New insights into activation of the steroid hormone receptor superfamily. Trends Pharmacol Sci 1992 0.97
34 A reappraisal of progesterone action in the mammary gland. J Mammary Gland Biol Neoplasia 2000 0.97
35 Cloning and structural organization of the gene encoding the murine nuclear receptor transcription factor, NURR1. Gene 1997 0.96
36 Regulation of epidermal Langerhans cell migration by lactoferrin. Immunology 2000 0.94
37 High level expression of a truncated chicken progesterone receptor in Escherichia coli. J Biol Chem 1990 0.94
38 Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid. Mol Endocrinol 1987 0.93
39 Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins. J Biol Chem 1991 0.91
40 Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors. J Biol Chem 1991 0.91
41 Restricted spatiotemporal expression of lactoferrin during murine embryonic development. Endocrinology 1999 0.89
42 Intramitochondrial movement of adrenal sterol carrier protein with cholesterol in response to corticotropin. Proc Natl Acad Sci U S A 1984 0.88
43 Interaction of the chicken progesterone receptor with heat shock protein (HSP) 90. J Steroid Biochem 1989 0.87
44 Structural organization and regulation of the chicken estrogen receptor. Mol Endocrinol 1987 0.84
45 The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat 2000 0.84
46 Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line. J Steroid Biochem Mol Biol 1997 0.83
47 An inducible expression system for the production of human lactoferrin in Aspergillus nidulans. Gene 1992 0.83
48 Cooperative interactions between the amino- and carboxyl-terminal lobes contribute to the unique iron-binding stability of lactoferrin. J Biol Chem 1996 0.83
49 Direct activity of recombinant human lactoferrin against Helicobacter pylori. J Clin Microbiol 1996 0.83
50 Production of biologically active recombinant human lactoferrin in Aspergillus oryzae. Biotechnology (N Y) 1992 0.82
51 In situ detection of progesterone receptor mRNA in the chicken oviduct using probe-on slides. Biotechniques 1990 0.82
52 Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia. Oncogenesis 2012 0.81
53 Reconstitution of estrogen-dependent transcriptional activation of an adenoviral target gene in select regions of the rat mammary gland. Endocrinology 1998 0.81
54 Reproductive tissue-selective actions of progesterone receptors. Ernst Schering Res Found Workshop 2005 0.80
55 Structural organization of the mouse lactoferrin gene. Biochem Biophys Res Commun 1992 0.80
56 The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2. Proc Natl Acad Sci U S A 1987 0.80
57 Nucleotide and primary amino acid sequence of porcine lactoferrin. Biochim Biophys Acta 1992 0.80
58 Expression and characterization of recombinant murine lactoferrin. Gene 1997 0.79
59 Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. Biochemistry 1993 0.78
60 Molecular cloning of a novel member of the nuclear receptor superfamily related to the orphan receptor, TR2. Gene Expr 1994 0.78
61 Corticotropin specifically stimulates the uptake and intracellular movements of sterol carrier protein in adrenals. Endocr Res 1986 0.78
62 A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. Gene 1992 0.77
63 Distribution of membrane cholesterol of adrenal cortical cells after corticotropin stimulation. Biochem J 1983 0.77
64 Restricted spatiotemporal expression of lactoferrin during murine embryogenesis. Adv Exp Med Biol 1998 0.75
65 Regulation by lactoferrin of epidermal Langerhans cell migration. Adv Exp Med Biol 1998 0.75
66 Commercial production of lactoferrin, a multifunctional iron-binding glycoprotein. Biotechnol Genet Eng Rev 1997 0.75
67 Oestrogen receptor activation in the absence of ligand. Biochem Soc Trans 1995 0.75
68 Molecular cloning, expression and evaluation of phosphohydrolases for phytate-degrading activity. J Ind Microbiol 1995 0.75