Published in Curr Opin Biotechnol on October 01, 1999
A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity. Proc Natl Acad Sci U S A (2000) 2.66
Remote control of neuronal signaling. Pharmacol Rev (2011) 2.66
Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. J Cell Biol (2001) 1.73
Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo. RNA (2000) 1.51
DsRed as a potential FRET partner with CFP and GFP. Biophys J (2003) 1.45
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs. Nucleic Acids Res (2001) 1.43
Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32). J Virol (2006) 1.34
Independent and high-level dual-gene expression in adult stem-progenitor cells from a single lentiviral vector. Gene Ther (2009) 1.13
Novel fluorescence-based screen to identify small synthetic internal ribosome entry site elements. Mol Cell Biol (2001) 1.07
Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors. BMC Biotechnol (2004) 0.99
Translation of the F protein of hepatitis C virus is initiated at a non-AUG codon in a +1 reading frame relative to the polyprotein. Nucleic Acids Res (2005) 0.96
Reprogramming axonal behavior by axon-specific viral transduction. Gene Ther (2012) 0.95
Protein coexpression using FMDV 2A: effect of "linker" residues. Biomed Res Int (2013) 0.92
Improvement of reporter activity by IRES-mediated polycistronic reporter system. Nucleic Acids Res (2008) 0.90
Conditional gene expression in the mouse inner ear using Cre-loxP. J Assoc Res Otolaryngol (2012) 0.89
Multimodal protein constructs for herbivore insect control. Toxins (Basel) (2012) 0.89
Optimisation of the foot-and-mouth disease virus 2A co-expression system for biomedical applications. BMC Biotechnol (2013) 0.88
Use of bicistronic vectors in combination with flow cytometry to screen for effective small interfering RNA target sequences. Biochem Biophys Res Commun (2010) 0.87
An internal ribosome entry site directs translation of the 3'-gene from Pelargonium flower break virus genomic RNA: implications for infectivity. PLoS One (2011) 0.85
The use of an adeno-associated viral vector for efficient bicistronic expression of two genes in the central nervous system. Methods Mol Biol (2014) 0.83
Rescuing infertility of Pick1 knockout mice by generating testis-specific transgenic mice via testicular infection. Sci Rep (2013) 0.83
Using RNA inverse folding to identify IRES-like structural subdomains. RNA Biol (2013) 0.83
An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells. PLoS One (2013) 0.81
Translational control of Scamper expression via a cell-specific internal ribosome entry site. Nucleic Acids Res (2003) 0.81
Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways. PLoS One (2015) 0.80
Tobacco etch virus protein P1 traffics to the nucleolus and associates with the host 60S ribosomal subunits during infection. J Virol (2014) 0.79
Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay. BMC Mol Biol (2010) 0.78
Efficient and reproducible generation of high-expressing, stable human cell lines without need for antibiotic selection. BMC Biotechnol (2008) 0.76
Engineering Strategies to Decode and Enhance the Genomes of Coral Symbionts. Front Microbiol (2017) 0.76
Angiostrongylus cantonensis cathepsin B-like protease (Ac-cathB-1) is involved in host gut penetration. Parasite (2015) 0.75
Robust Transgene Expression from Bicistronic mRNA in the Green Alga Chlamydomonas reinhardtii. G3 (Bethesda) (2016) 0.75
Construction of recombinant adenovirus containing picorna-viral 2A-peptide sequence for the co-expression of neuro-protective growth factors in human umbilical cord blood cells. Spinal Cord (2015) 0.75
Live Attenuated Vaccine Based on Duck Enteritis Virus against Duck Hepatitis A Virus Types 1 and 3. Front Microbiol (2016) 0.75