Published in Lancet on October 23, 1999
Dengue virus structural differences that correlate with pathogenesis. J Virol (1999) 4.26
Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons. J Virol (2000) 3.61
Microevolution and virulence of dengue viruses. Adv Virus Res (2003) 3.41
Ecological and immunological determinants of dengue epidemics. Proc Natl Acad Sci U S A (2006) 2.92
Recent advances in deciphering viral and host determinants of dengue virus replication and pathogenesis. J Virol (2006) 2.76
Dengue: defining protective versus pathologic immunity. J Clin Invest (2004) 2.73
Selection for virulent dengue viruses occurs in humans and mosquitoes. J Virol (2005) 2.50
Infection of human cells by dengue virus is modulated by different cell types and viral strains. J Virol (2000) 2.49
Invasion and maintenance of dengue virus type 2 and type 4 in the Americas. J Virol (2005) 2.44
Clade replacements in dengue virus serotypes 1 and 3 are associated with changing serotype prevalence. J Virol (2005) 2.35
Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Sci Transl Med (2011) 2.29
Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus. Vector Borne Zoonotic Dis (2001) 2.20
Epidemiology of dengue virus in Iquitos, Peru 1999 to 2005: interepidemic and epidemic patterns of transmission. PLoS Negl Trop Dis (2010) 2.17
Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti. Am J Trop Med Hyg (2003) 2.16
Aedes aegypti vectorial capacity is determined by the infecting genotype of dengue virus. Am J Trop Med Hyg (2006) 2.07
American genotype structures decrease dengue virus output from human monocytes and dendritic cells. J Virol (2003) 2.03
Dengue hemorrhagic fever in infants: research opportunities ignored. Emerg Infect Dis (2002) 2.03
Dynamic effects of antibody-dependent enhancement on the fitness of viruses. Proc Natl Acad Sci U S A (2005) 2.02
Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E. PLoS Pathog (2007) 1.97
The history of dengue outbreaks in the Americas. Am J Trop Med Hyg (2012) 1.87
Fever from the forest: prospects for the continued emergence of sylvatic dengue virus and its impact on public health. Nat Rev Microbiol (2011) 1.86
Dengue virus evolution and virulence models. Clin Infect Dis (2007) 1.64
Dengue virus serotype 4, northeastern Peru, 2008. Emerg Infect Dis (2009) 1.63
Mosquitoes put the brake on arbovirus evolution: experimental evolution reveals slower mutation accumulation in mosquito than vertebrate cells. PLoS Pathog (2009) 1.56
Natural attenuation of dengue virus type-2 after a series of island outbreaks: a retrospective phylogenetic study of events in the South Pacific three decades ago. Virology (2010) 1.53
Dengue--quo tu et quo vadis? Viruses (2011) 1.50
Potential of ancestral sylvatic dengue-2 viruses to re-emerge. Virology (2006) 1.49
The early whole-blood transcriptional signature of dengue virus and features associated with progression to dengue shock syndrome in Vietnamese children and young adults. J Virol (2010) 1.47
Superior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virus. BMC Ecol (2008) 1.41
Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2. BMC Infect Dis (2004) 1.35
Neutralizing antibodies after infection with dengue 1 virus. Emerg Infect Dis (2007) 1.33
Time-varying, serotype-specific force of infection of dengue virus. Proc Natl Acad Sci U S A (2014) 1.33
Spatial dimensions of dengue virus transmission across interepidemic and epidemic periods in Iquitos, Peru (1999-2003). PLoS Negl Trop Dis (2012) 1.32
Use of a short fragment of the C-terminal E gene for detection and characterization of two new lineages of dengue virus 1 in India. J Clin Microbiol (2006) 1.32
Diabetes with hypertension as risk factors for adult dengue hemorrhagic fever in a predominantly dengue serotype 2 epidemic: a case control study. PLoS Negl Trop Dis (2012) 1.29
Reduced risk of disease during postsecondary dengue virus infections. J Infect Dis (2013) 1.25
Clinical findings and pro-inflammatory cytokines in dengue patients in Western India: a facility-based study. PLoS One (2010) 1.23
Asymmetric competitive suppression between strains of dengue virus. BMC Microbiol (2008) 1.21
Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response. J Virol (2000) 1.18
Clinical and virological study of dengue cases and the members of their households: the multinational DENFRAME Project. PLoS Negl Trop Dis (2012) 1.17
A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis. J Virol (2011) 1.17
Assessing and maximizing the acceptability of global positioning system device use for studying the role of human movement in dengue virus transmission in Iquitos, Peru. Am J Trop Med Hyg (2010) 1.14
Meta-analysis of all immune epitope data in the Flavivirus genus: inventory of current immune epitope data status in the context of virus immunity and immunopathology. Viral Immunol (2010) 1.14
Correlation of serotype-specific dengue virus infection with clinical manifestations. PLoS Negl Trop Dis (2012) 1.13
Assessing the potential of a candidate dengue vaccine with mathematical modeling. PLoS Negl Trop Dis (2012) 1.11
Long-term and seasonal dynamics of dengue in Iquitos, Peru. PLoS Negl Trop Dis (2014) 1.10
Acute arboviral infections in Guinea, West Africa, 2006. Am J Trop Med Hyg (2010) 1.08
Initial assessment of the acceptability of a Push-Pull Aedes aegypti control strategy in Iquitos, Peru and Kanchanaburi, Thailand. Am J Trop Med Hyg (2011) 1.05
Zika Virus Emergence and Expansion: Lessons Learned from Dengue and Chikungunya May Not Provide All the Answers. Am J Trop Med Hyg (2016) 1.03
Understanding the dengue viruses and progress towards their control. Biomed Res Int (2013) 1.02
Identification of clinical factors associated with severe dengue among Thai adults: a prospective study. BMC Infect Dis (2015) 1.02
Laboratory surveillance of dengue in Argentina, 1995-2001. Emerg Infect Dis (2003) 1.02
Validation of probability equation and decision tree in predicting subsequent dengue hemorrhagic fever in adult dengue inpatients in Singapore. Am J Trop Med Hyg (2011) 1.01
The impact of transgenic mosquitoes on dengue virulence to humans and mosquitoes. Am Nat (2009) 1.01
Fever versus fever: the role of host and vector susceptibility and interspecific competition in shaping the current and future distributions of the sylvatic cycles of dengue virus and yellow fever virus. Infect Genet Evol (2013) 0.99
Circulation of different lineages of Dengue virus 2, genotype American/Asian in Brazil: dynamics and molecular and phylogenetic characterization. PLoS One (2013) 0.97
Variation in virulence of dengue virus. Lancet (1999) 0.96
Emergence of the severe syndrome and mortality associated with dengue and dengue-like illness: historical records (1890 to 1950) and their compatibility with current hypotheses on the shift of disease manifestation. Clin Microbiol Rev (2009) 0.95
Controversies in dengue pathogenesis. Paediatr Int Child Health (2012) 0.95
Both viremia and cytokine levels associate with the lack of severe disease in secondary dengue 1 infection among adult Chinese patients. PLoS One (2010) 0.92
Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis. Nat Rev Microbiol (2013) 0.91
Lineage II of Southeast Asian/American DENV-2 is associated with a severe dengue outbreak in the Peruvian Amazon. Am J Trop Med Hyg (2014) 0.88
Difference between the abilities of human Fcgamma receptor-expressing CV-1 cells to neutralize American and Asian genotypes of dengue virus 2. Clin Vaccine Immunol (2008) 0.88
Phylogenetic reconstruction of dengue virus type 2 in Colombia. Virol J (2012) 0.87
Evaluation of location-specific predictions by a detailed simulation model of Aedes aegypti populations. PLoS One (2011) 0.87
Breaking the symmetry: immune enhancement increases persistence of dengue viruses in the presence of asymmetric transmission rates. J Theor Biol (2013) 0.86
Conservation of the DENV-2 type-specific and DEN complex-reactive antigenic sites among DENV-2 genotypes. Virology (2011) 0.85
Homology of complete genome sequences for dengue virus type-1, from dengue-fever- and dengue-haemorrhagic-fever-associated epidemics in Hawaii and French Polynesia. Ann Trop Med Parasitol (2010) 0.84
Specific genetic markers for detecting subtypes of dengue virus serotype-2 in isolates from the states of Oaxaca and Veracruz, Mexico. BMC Microbiol (2008) 0.83
Incomplete Protection against Dengue Virus Type 2 Re-infection in Peru. PLoS Negl Trop Dis (2016) 0.81
Association between nutritional status and dengue infection: a systematic review and meta-analysis. BMC Infect Dis (2016) 0.80
Role of cognitive parameters in dengue hemorrhagic fever and dengue shock syndrome. J Biomed Sci (2013) 0.80
Variation in inflammatory/regulatory cytokines in secondary, tertiary, and quaternary challenges with dengue virus. Am J Trop Med Hyg (2012) 0.78
High producing tumor necrosis factor alpha gene alleles in protection against severe manifestations of dengue. Int J Med Sci (2015) 0.78
Meta-Analysis of Dengue Severity during Infection by Different Dengue Virus Serotypes in Primary and Secondary Infections. PLoS One (2016) 0.78
The molecular and clinical features of dengue during outbreak in Jambi, Indonesia in 2015. Pathog Glob Health (2016) 0.76
Phylogenetic analysis of the envelope protein (domain III) of dengue 4 viruses. Salud Publica Mex (2002) 0.75
Differential replicative ability of clinical dengue virus isolates in an immunocompetent C57BL/6 mouse model. BMC Microbiol (2015) 0.75
Capturing the dynamics of pathogens with many strains. J Math Biol (2015) 0.75
Genomic approaches for understanding dengue: insights from the virus, vector, and host. Genome Biol (2016) 0.75
Some Artifacts Encountered in Stained Preparations of Tubercle Bacilli: I. Non-Acid-fast Forms Arising From Mechanical Treatment. J Bacteriol (1944) 7.94
Is there an inapparent dengue explosion? Lancet (1999) 7.28
Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody. J Exp Med (1977) 7.01
Cytoplasmic fibrils in living cultured cells. A light and electron microscope study. Protoplasma (1967) 6.38
Morphology of Microtubules of Plant Cell. Science (1964) 6.22
Fine structure of cell division in Chlamydomonas reinhardi. Basal bodies and microtubules. J Cell Biol (1968) 5.83
Human skin Langerhans cells are targets of dengue virus infection. Nat Med (2000) 5.74
Studies on the microtubules in heliozoa. II. The effect of low temperature on these structures in the formation and maintenance of the axopodia. J Cell Biol (1967) 5.67
Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak. Am J Epidemiol (1984) 5.62
Studies on microtubules in Heliozoa. I. The fine structure of Actinosphaerium nucleofilum (Barrett), with particular reference to the axial rod structure. Protoplasma (1965) 5.31
The Fine Structure of the Parenchymal Cell of the Normal Rat Liver: I. General Observations. Am J Pathol (1965) 5.30
THE FINE STRUCTURE OF CLOTS FORMED FROM PURIFIED BOVINE FIBRINOGEN AND THROMBIN: A STUDY WITH THE ELECTRON MICROSCOPE. J Exp Med (1947) 4.70
Microtrabecular lattice of the cytoplasmic ground substance. Artifact or reality. J Cell Biol (1979) 4.61
Observations related to pathogensis of dengue hemorrhagic fever. VI. Hypotheses and discussion. Yale J Biol Med (1970) 4.41
Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever. Am J Trop Med Hyg (1969) 4.41
Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol Med (1970) 4.30
Antibody-enhanced dengue virus infection in primate leukocytes. Nature (1977) 4.18
In vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody. J Infect Dis (1979) 3.90
Rubella: reinfection of vaccinated and naturally immune persons exposed in an epidemic. N Engl J Med (1970) 3.88
Epidemiologic studies on Dengue in Santiago de Cuba, 1997. Am J Epidemiol (2000) 3.70
Detection of diverse HIV-1 genetic subtypes in the USA. Lancet (1995) 3.41
Rethinking mitosis. Cell (1982) 3.34
Effectiveness of live-attenuated Japanese encephalitis vaccine (SA14-14-2): a case-control study. Lancet (1996) 3.30
Hemorrhagic fevers of Southeast Asia and South America: a comparative appraisal. Prog Med Virol (1967) 3.22
Stereo high-voltage electron microscopy of whole cells of the human diploid line, WI-38. Am J Anat (1976) 3.06
Microtubules in the spermatids of the domestic fowl. J Cell Biol (1967) 2.85
An electron microscopy study of the effects on dibutyryl cyclic AMP on Chinese hamster ovary cells. Cell (1974) 2.85
Dengue viruses and mononuclear phagocytes. II. Identity of blood and tissue leukocytes supporting in vitro infection. J Exp Med (1977) 2.84
Original antigenic sin in dengue. Am J Trop Med Hyg (1983) 2.82
Microtrabecular structure of the axoplasmic matrix: visualization of cross-linking structures and their distribution. J Cell Biol (1980) 2.81
A prospective seroepidemiologic study on dengue in children four to nine years of age in Yogyakarta, Indonesia I. studies in 1995-1996. Am J Trop Med Hyg (1999) 2.78
Development and evaluation of serotype- and group-specific fluorogenic reverse transcriptase PCR (TaqMan) assays for dengue virus. J Clin Microbiol (2001) 2.75
Dengue and chikungunya virus infection in man in Thailand, 1962-1964. IV. Epidemiologic studies in the Bangkok metropolitan area. Am J Trop Med Hyg (1969) 2.62
A "MICROTUBULE" IN PLANT CELL FINE STRUCTURE. J Cell Biol (1963) 2.48
Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection. J Infect Dis (1973) 2.48
Respiratory hospital admissions and summertime haze air pollution in Toronto, Ontario: consideration of the role of acid aerosols. Environ Res (1994) 2.47
A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells. J Cell Biol (1984) 2.46
Shock associated with dengue infection. I. Clinical and physiologic manifestations of dengue hemorrhagic fever in Thailand, 1964. J Pediatr (1966) 2.45
Dengue haemorrhagic fever--a public health problem and a field for research. Bull World Health Organ (1980) 2.39
Mosquito-borne haemorrhagic fevers of South and South-East Asia. Bull World Health Organ (1966) 2.39
Haiti: absence of dengue hemorrhagic fever despite hyperendemic dengue virus transmission. Am J Trop Med Hyg (2001) 2.35
Simplified plaque reduction neutralization assay for dengue viruses by semimicro methods in BHK-21 cells: comparison of the BHK suspension test with standard plaque reduction neutralization. J Clin Microbiol (1985) 2.31
A scanning electron microscope study of surface features of viral and spontaneous transformants of mouse Balb-3T3 cells. J Cell Biol (1973) 2.30
The cytomatrix: a short history of its study. J Cell Biol (1984) 2.19
Protective efficacy of oral whole-cell/recombinant-B-subunit cholera vaccine in Peruvian military recruits. Lancet (1994) 2.16
Centriole replication during ciliogenesis in the chick tracheal epithelium. Z Zellforsch Mikrosk Anat (1969) 2.13
Observations related to the pathogenesis of dengue hemorrhagic fever. II. Antigenic and biologic properties of dengue viruses and their association with disease response in the host. Yale J Biol Med (1970) 2.13
Dengue d chikungunya virus infection in man in Thailand, 1962-1964. II. Observations on disease in outpatients. Am J Trop Med Hyg (1969) 2.11
Detection of West Nile virus by the polymerase chain reaction and analysis of nucleotide sequence variation. Am J Trop Med Hyg (1993) 2.07
Dengue chikungunya virus infection in man in Thailand, 1962-1964. 3. Clinical, epidemiologic, and virologic observations on disease in non-indigenous white persons. Am J Trop Med Hyg (1969) 2.07
Stabilization and the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition. Proc Natl Acad Sci U S A (1981) 2.05
Intestinal triglyceride absorption in the rat. An electron microscopical study. J Cell Biol (1967) 2.05
Electron microscopy of critical point dried whole cultured cells. J Microsc (1975) 2.04
The cytoplasmic matrix: its volume and surface area and the diffusion of molecules through it. Proc Natl Acad Sci U S A (1985) 2.01
Studies of excitable membranes. II. A comparison of specializations at neuromuscular junctions and nonjunctional sarcolemmas of mammalian fast and slow twitch muscle fibers. J Cell Biol (1976) 1.97
Hemorrhagic fever in Thailand; recent knowledge regarding etiology. Jpn J Med Sci Biol (1967) 1.94
Immune enhancement of viral infection. Prog Allergy (1982) 1.94
Mayaro virus disease: an emerging mosquito-borne zoonosis in tropical South America. Clin Infect Dis (1999) 1.93
Vertical transmission of West Nile virus by Culex and Aedes species mosquitoes. Am J Trop Med Hyg (1993) 1.86
The Alexander D. Langmuir Lecture. The pathogenesis of dengue. Molecular epidemiology in infectious disease. Am J Epidemiol (1981) 1.85
Dengue fever in U.S. troops during Operation Restore Hope, Somalia, 1992-1993. Am J Trop Med Hyg (1995) 1.81
The ground substance of the living cell. Sci Am (1981) 1.81
Evaluation of a dipstick enzyme-linked immunosorbent assay for detection of antibodies to dengue virus. Clin Diagn Lab Immunol (1997) 1.78
Detection of Francisella tularensis in blood by polymerase chain reaction. J Clin Microbiol (1993) 1.75
Transformations in the structure of the cytoplasmic ground substance in erythrophores during pigment aggregation and dispersion. I. A study using whole-cell preparations in stereo high voltage electron microscopy. J Cell Biol (1977) 1.70
Superomedial pedicle technique of reduction mammaplasty. Plast Reconstr Surg (1989) 1.68
Changing association between community occupational structure and ischaemic heart disease mortality in the United States. Lancet (1987) 1.67
Selective primary health care: strategies for control of disease in the developing world. XI. Dengue. Rev Infect Dis (1984) 1.66
Enhancement of dengue virus infection in monocytes by flavivirus antisera. Am J Trop Med Hyg (1980) 1.65
Specializations of the unit membrane. Protoplasma (1967) 1.64
Sustained reduction of proteinuria in type 2 (non-insulin-dependent) diabetes following diet-induced reduction of hyperglycaemia. Diabetologia (1984) 1.60
Microtubules in the formation and development of the primary mesenchyme in Arbacia punctulata. I. The distribution of microtubules. J Cell Biol (1969) 1.60
Dengue virus replication enhancement in peripheral blood leukocytes from immune human beings. Proc Soc Exp Biol Med (1976) 1.60
Panel studies of acute health effects of air pollution. I. Cardiopulmonary symptoms in adults, New York, 1971-1972. Environ Res (1976) 1.60
Isolation of viruses from mosquitoes (Diptera: Culicidae) collected in the Amazon Basin region of Peru. J Med Entomol (2005) 1.57
Microtubules in intracellular locomotion. Ciba Found Symp (1973) 1.56
Studies on the pathogenesis of dengue infection in monkeys. I. Clinical laboratory responses to primary infection. J Infect Dis (1973) 1.55
Heterogeneity of infection enhancement of dengue 2 strains by monoclonal antibodies. J Immunol (1984) 1.54
The epidemiology of malaria in an epidemic area of the Peruvian Amazon. Am J Trop Med Hyg (2000) 1.52
Inhibitors of dynein activity block intracellular transport in erythrophores. Nature (1982) 1.52
Epidemic dengue transmission in southern Sumatra, Indonesia. Trans R Soc Trop Med Hyg (2001) 1.51
In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus. J Clin Invest (1983) 1.50
Etiologies of the experimental dengues of Siler and Simmons. Am J Trop Med Hyg (1974) 1.49
Replication of dengue viruses in cultures of peripheral blood leukocytes from dengue-immune rhesus monkeys. J Infect Dis (1976) 1.49
Observations related to pathogenesis of dengue hemorrhagic fever. 3. Virologic studies of fatal disease. Yale J Biol Med (1970) 1.48
Antibody response in dengue and dengue hemorrhagic fever. Jpn J Med Sci Biol (1967) 1.47
Human immunodeficiency virus type 1 neutralizing antibody serotyping using serum pools and an infectivity reduction assay. AIDS Res Hum Retroviruses (1996) 1.46
Venezuelan equine encephalitis and Oropouche virus infections among Peruvian army troops in the Amazon region of Peru. Am J Trop Med Hyg (1997) 1.45
Observations related to pathogenesis of dengue hemorrhagic fever. I. Experience with classification of dengue viruses. Yale J Biol Med (1970) 1.45
Dengue and chikungunya virus infection in man in Thailand, 1962-1964. V. Epidemiologic observations outside Bangkok. Am J Trop Med Hyg (1969) 1.44
Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections. J Infect Dis (1973) 1.42
Measurement of antibody-dependent infection enhancement of four dengue virus serotypes by monoclonal and polyclonal antibodies. J Gen Virol (1990) 1.40
Positive response to edrophonium in patients with neurotoxic envenoming by cobras (Naja naja philippinensis). A placebo-controlled study. N Engl J Med (1986) 1.40
Epidemic keratoconjunctivitis at a U.S. military base: Republic of the Philippines. Mil Med (1991) 1.39