K T Kivistö

Author PubWeight™ 72.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 1998 2.09
2 Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 1998 1.99
3 Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1998 1.49
4 Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clin Pharmacol Ther 1998 1.42
5 Activated charcoal alone and followed by whole-bowel irrigation in preventing the absorption of sustained-release drugs. Clin Pharmacol Ther 2001 1.40
6 Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999 1.34
7 The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin. Eur J Clin Pharmacol 1998 1.33
8 Interference of dairy products with the absorption of ciprofloxacin. Clin Pharmacol Ther 1991 1.32
9 Plasma concentrations of active simvastatin acid are increased by gemfibrozil. Clin Pharmacol Ther 2000 1.24
10 Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease. Neurology 2007 1.22
11 Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide. Clin Pharmacol Ther 2001 1.19
12 Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 1998 1.13
13 In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9). Br J Clin Pharmacol 2001 1.08
14 Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9. Drug Metab Dispos 2001 1.04
15 Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans. Drug Metab Dispos 2000 1.04
16 Rifampin decreases the plasma concentrations and effects of repaglinide. Clin Pharmacol Ther 2000 1.04
17 Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 2000 1.03
18 The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide. Clin Pharmacol Ther 2001 1.00
19 The clinical significance of food-drug interactions: a review. Med J Aust 1989 1.00
20 Milk and yoghurt do not impair the absorption of ofloxacin. Br J Clin Pharmacol 1992 1.00
21 Grapefruit juice substantially increases plasma concentrations of buspirone. Clin Pharmacol Ther 1998 0.98
22 Failure of oral activated charcoal to accelerate the elimination of amiodarone and chloroquine. Hum Exp Toxicol 1992 0.98
23 Effect of magnesium hydroxide on the absorption of tolfenamic and mefenamic acids. Eur J Clin Pharmacol 1988 0.97
24 Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site. Cancer Res 1997 0.95
25 A prospective study of acute poisonings in Finnish hospital patients. Hum Exp Toxicol 1998 0.95
26 Triazolam is ineffective in patients taking rifampin. Clin Pharmacol Ther 1997 0.94
27 Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate. Clin Pharmacol Ther 2001 0.94
28 Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole. Pharmacol Toxicol 1999 0.92
29 Identification of drugs ingested in acute poisoning: correlation of patient history with drug analyses. Ther Drug Monit 2000 0.92
30 Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors. Clin Pharmacol Ther 1999 0.91
31 Concentrations and effects of buspirone are considerably reduced by rifampicin. Br J Clin Pharmacol 1998 0.91
32 Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated consumption prolongs triazolam half-life. Eur J Clin Pharmacol 2000 0.90
33 Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration. Br J Clin Pharmacol 1997 0.89
34 Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride. Clin Pharmacol Ther 2001 0.87
35 The effect of activated charcoal on the absorption of fluoxetine, with special reference to delayed charcoal administration. Pharmacol Toxicol 1996 0.87
36 Effect of sucralfate on absorption of norfloxacin and ofloxacin. Antimicrob Agents Chemother 1994 0.87
37 Effect of activated charcoal on the pharmacokinetics of pholcodine, with special reference to delayed charcoal ingestion. Ther Drug Monit 1997 0.86
38 Clozapine serum concentrations are lower in smoking than in non-smoking schizophrenic patients. Pharmacol Toxicol 1999 0.86
39 The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin. Br J Clin Pharmacol 1994 0.86
40 Effect of an oral contraceptive preparation containing ethinylestradiol and gestodene on CYP3A4 activity as measured by midazolam 1'-hydroxylation. Br J Clin Pharmacol 2000 0.86
41 Enhancement of drug absorption by antacids. An unrecognised drug interaction. Clin Pharmacokinet 1994 0.86
42 Effect of fluconazole on plasma fluvastatin and pravastatin concentrations. Eur J Clin Pharmacol 2000 0.85
43 Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride. Clin Pharmacol Ther 2001 0.85
44 Effect of methylprednisolone on CYP3A4-mediated drug metabolism in vivo. Eur J Clin Pharmacol 2001 0.84
45 Efficacy of activated charcoal versus gastric lavage half an hour after ingestion of moclobemide, temazepam, and verapamil. Eur J Clin Pharmacol 2000 0.84
46 Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Clin Pharmacol Ther 2000 0.84
47 The ex-vivo isolated, perfused human lung model: description and potential applications. Thorac Cardiovasc Surg 1996 0.83
48 Rifampin reduces plasma concentrations and effects of zolpidem. Clin Pharmacol Ther 1997 0.83
49 Different effects of products containing metal ions on the absorption of lomefloxacin. Clin Pharmacol Ther 1994 0.83
50 Effect of delayed administration of activated charcoal on the absorption of conventional and slow-release verapamil. J Toxicol Clin Toxicol 1997 0.82
51 Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram. Br J Clin Pharmacol 1999 0.82
52 Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000 0.81
53 Misleading use of correlation and regression in method-comparison studies of cyclosporine. Clin Chem 1993 0.81
54 Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride. Br J Clin Pharmacol 2000 0.81
55 Concentrations and effects of zopiclone are greatly reduced by rifampicin. Br J Clin Pharmacol 1997 0.80
56 Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methylprednisolone. Clin Pharmacol Ther 2000 0.80
57 Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone. Clin Pharmacol Ther 1998 0.79
58 The effect of fluvoxamine on the pharmacokinetics and pharmacodynamics of buspirone. Eur J Clin Pharmacol 1999 0.79
59 The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone. Eur J Clin Pharmacol 2000 0.79
60 Pharmacokinetics of diltiazem in massive overdose. Ther Drug Monit 1997 0.79
61 Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zolpidem. Eur J Clin Pharmacol 1998 0.79
62 The effect of dexamethasone on the pharmacokinetics of triazolam. Pharmacol Toxicol 1998 0.78
63 Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. Pharmacol Toxicol 1999 0.78
64 Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers. Pharmacol Toxicol 1999 0.78
65 The effects of magnesium hydroxide on the absorption and efficacy of two glibenclamide preparations. Br J Clin Pharmacol 1991 0.77
66 Stereoselective pharmacokinetics of cisapride in healthy volunteers and the effect of repeated administration of grapefruit juice. Br J Clin Pharmacol 2001 0.77
67 Effect of itraconazole on cerivastatin pharmacokinetics. Eur J Clin Pharmacol 1999 0.77
68 Lack of effect of terfenadine on the pharmacokinetics of the CYP3A4 substrate buspirone. Pharmacol Toxicol 1999 0.77
69 The cytochrome P450 3A4 inhibitor itraconazole markedly increases the plasma concentrations of dexamethasone and enhances its adrenal-suppressant effect. Clin Pharmacol Ther 2000 0.77
70 Prevention of chloroquine absorption by activated charcoal. Hum Exp Toxicol 1992 0.77
71 Grapefruit juice can increase the plasma concentrations of oral methylprednisolone. Eur J Clin Pharmacol 2000 0.77
72 Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole. Clin Pharmacol Ther 1998 0.77
73 Gastric decontamination performed 5 min after the ingestion of temazepam, verapamil and moclobemide: charcoal is superior to lavage. Br J Clin Pharmacol 2000 0.77
74 Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial. Clin Pharmacol Ther 2008 0.76
75 Effects of metronidazole on midazolam metabolism in vitro and in vivo. Eur J Clin Pharmacol 2000 0.75
76 Effects of milk and food on the absorption of enoxacin. Br J Clin Pharmacol 1995 0.75
77 Activated charcoal for chloroquine poisoning. BMJ 1993 0.75
78 Activated charcoal should replace the resins in the treatment of digoxin intoxication! Arch Intern Med 1989 0.75
79 Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam. Clin Pharmacol Ther 1999 0.75
80 Therapeutic cyclosporine monitoring: comparison of radioimmunoassay and high-performance liquid chromatography methods in organ transplant recipients. Ther Drug Monit 1990 0.75
81 The effects of glyceryl trinitrate and nicotinic acid ointments during cold exposure. Pharmacol Toxicol 1997 0.75
82 The effect of rifampin on the pharmacokinetics of oral and intravenous ondansetron. Clin Pharmacol Ther 1999 0.75
83 Quantitative immunohistochemical analysis of the glutathione S-transferase GSTM1: in situ phenotyping in archival material. Xenobiotica 1999 0.75
84 Desorption of furosemide from charcoal in vitro and in man. Int J Clin Pharmacol Ther 1994 0.75
85 The effect of pH on the in-vitro dissolution of three second-generation sulphonylurea preparations: mechanism of antacid-sulphonylurea interaction. J Pharm Pharmacol 1996 0.75
86 The effect of activated charcoal on the absorption and elimination of astemizole. Hum Exp Toxicol 1994 0.75