Published in Ann Neurol on November 01, 1999
Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging. Neuropathol Appl Neurobiol (2015) 1.86
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am J Pathol (2006) 1.68
A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia. Neurology (2006) 1.62
Long-term assessment of striatal dopamine transporters in Parkinsonian patients with intrastriatal embryonic mesencephalic grafts. Eur J Nucl Med Mol Imaging (2006) 1.46
Piericidin A aggravates Tau pathology in P301S transgenic mice. PLoS One (2014) 1.40
The cytoskeleton in neurodegenerative diseases. J Pathol (2004) 1.35
Proteopathic tau seeding predicts tauopathy in vivo. Proc Natl Acad Sci U S A (2014) 1.28
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy. Hum Mol Genet (2011) 1.12
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Orphanet J Rare Dis (2006) 0.97
The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Front Neurosci (2015) 0.91
Alternative splicing of exon 10 in the tau gene as a target for treatment of tauopathies. BMC Neurosci (2008) 0.89
Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation. J Neural Transm (Vienna) (2007) 0.88
The aetiology of idiopathic Parkinson's disease. Mol Pathol (2001) 0.88
Tau mutants bind tubulin heterodimers with enhanced affinity. Proc Natl Acad Sci U S A (2014) 0.85
Familial autosomal dominant cortico-basal degeneration with the P301S mutation in the tau gene: an example of phenotype variability. J Neurol (2005) 0.82
Parkinsonism, movement disorders and genetics in frontotemporal dementia. Nat Rev Neurol (2016) 0.79
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathol Commun (2013) 0.79
Cellular factors modulating the mechanism of tau protein aggregation. Cell Mol Life Sci (2015) 0.79
FTDP-17: phenotypical heterogeneity within P301S. Ann Neurol (2000) 0.78
Characterization of Movement Disorder Phenomenology in Genetically Proven, Familial Frontotemporal Lobar Degeneration: A Systematic Review and Meta-Analysis. PLoS One (2016) 0.78
Novel G335V mutation in the tau gene associated with early onset familial frontotemporal dementia. Neurogenetics (2005) 0.78
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathol (2015) 0.77
Tau physiology and pathomechanisms in frontotemporal lobar degeneration. J Neurochem (2016) 0.76
Systematic review and meta-analysis of Japanese familial Alzheimer's disease and FTDP-17. J Hum Genet (2015) 0.75
Seizures in corticobasal degeneration: a case report. Neurocase (2009) 0.75
Clinicopathologic heterogeneity in FTDP-17 due to MAPT p.P301L mutation, including a patient with globular glial tauopathy. Neuropathol Appl Neurobiol (2016) 0.75
Epilepsy in the elderly: Special considerations and challenges. Ann Indian Acad Neurol (2014) 0.75
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature (1998) 15.24
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science (1997) 5.54
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy. Nat Genet (1998) 3.62
n of 1 trials comparing a non-steroidal anti-inflammatory drug with paracetamol in osteoarthritis. BMJ (1994) 3.34
DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology (2007) 2.86
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin. Science (1987) 2.48
Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog. Neuron (2001) 2.38
Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression. Neuroscience (2005) 2.36
A radiation hybrid map of the zebrafish genome. Nat Genet (1999) 2.31
CSF filtration is an effective treatment of Guillain-Barré syndrome: a randomized clinical trial. Neurology (2001) 2.16
Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology (2004) 2.14
Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci (1995) 2.10
Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group. Mov Disord (2000) 2.10
Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish. J Neurosci (1999) 2.07
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Neurol Sci (2003) 1.90
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am J Hum Genet (1999) 1.87
Multiple cerebral aneurysms as delayed complication of left cardiac myxoma: a case report and review. Acta Neurol Scand (2005) 1.87
Sputum examination for the diagnosis of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Am Rev Respir Dis (1986) 1.84
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease. Neurology (2004) 1.83
Normal IPT and IBZM SPECT in drug-naive and levodopa-treated idiopathic restless legs syndrome. Neurology (2001) 1.83
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat Genet (2001) 1.83
EANM procedure guidelines for brain tumour imaging using labelled amino acid analogues. Eur J Nucl Med Mol Imaging (2006) 1.79
CSF glial markers correlate with survival in amyotrophic lateral sclerosis. Neurology (2010) 1.77
A new gene, encoding an anion transporter, is mutated in sialic acid storage diseases. Nat Genet (1999) 1.76
Familial aggregation in frontotemporal dementia. Neurology (1998) 1.76
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes (2001) 1.76
Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options. Eur J Neurol (2009) 1.76
Laparoscopic transperitoneal procedure for routine repair of groin hernia. Br J Surg (2002) 1.75
Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype. Ann Neurol (1999) 1.74
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. Am J Hum Genet (2001) 1.71
Axonal damage markers in cerebrospinal fluid are increased in ALS. Neurology (2006) 1.69
Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11. Hum Mol Genet (1994) 1.68
Familial aggregation of parkinsonism in progressive supranuclear palsy. Neurology (2009) 1.68
Perinatal cerebral intraventricular hemorrhage. J Pediatr (1972) 1.66
The combination of hypointense and hyperintense signal changes on T2-weighted magnetic resonance imaging sequences: a specific marker of multiple system atrophy? Arch Neurol (1999) 1.66
[Standardized laparoscopic hernioplasty vs. Shouldice repair. Results of a randomized comparative study]. Chirurg (1995) 1.65
Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. Neurosci Lett (2000) 1.65
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Mol Psychiatry (2010) 1.63
Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A double-blind, placebo-controlled trial. N Engl J Med (1990) 1.61
Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22. Brain (2001) 1.59
Paroxysmal choreoathetosis/spasticity (DYT9) is caused by a GLUT1 defect. Neurology (2011) 1.58
Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry (2012) 1.57
Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. Eur J Hum Genet (2002) 1.56
Inguinal hernia repair: current surgical techniques. Langenbecks Arch Surg (2011) 1.56
Histoplasmosis in immunosuppressed patients. Am J Med (1978) 1.54
Hereditary vascular retinopathy, cerebroretinal vasculopathy, and hereditary endotheliopathy with retinopathy, nephropathy, and stroke map to a single locus on chromosome 3p21.1-p21.3. Am J Hum Genet (2001) 1.54
Phenotypic expression of the DYT1 mutation: a family with writer's cramp of juvenile onset. Ann Neurol (1998) 1.53
Influence of thyroid-stimulating hormone levels on uptake of FDG in recurrent and metastatic differentiated thyroid carcinoma. J Nucl Med (2000) 1.50
Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau. Am J Pathol (1998) 1.50
Skin involvement in amyotrophic lateral sclerosis. Lancet (1996) 1.49
Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol (1992) 1.49
Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment. Eur J Nucl Med (2000) 1.48
Zebrafish mutations affecting retinotectal axon pathfinding. Development (1996) 1.47
Proton magnetic resonance spectroscopy in Kennedy syndrome. Arch Neurol (1999) 1.44
Perception of Fourier and non-Fourier motion by larval zebrafish. Nat Neurosci (2000) 1.43
Indium-111 pentetreotide in the diagnostic work-up of patients with bronchogenic carcinoma. Eur J Nucl Med (1994) 1.42
Genome-wide association study of Tourette's syndrome. Mol Psychiatry (2012) 1.42
[Neurogenesis in the adult brain: from bench to bedside?]. Fortschr Neurol Psychiatr (2008) 1.41
Falls among healthy, community-dwelling, older women: a prospective study of frequency, circumstances, consequences and prediction accuracy. Aust N Z J Public Health (1999) 1.41
A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36. Genomics (1999) 1.40
Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome. Hum Mol Genet (1999) 1.40
Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety. Proc Natl Acad Sci U S A (2001) 1.39
D2 receptor occupancy under recommended and high doses of olanzapine: an iodine-123-iodobenzamide SPECT study. J Psychopharmacol (2000) 1.39
Phenotypic variation in hereditary frontotemporal dementia with tau mutations. Ann Neurol (1999) 1.39
Acute encephalopathy with vigabatrin. Lancet (1993) 1.38
Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene. Am J Hum Genet (2000) 1.38
Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Comparison with Parkinson's disease and controls. Brain (2000) 1.35
Clinical and genetic studies on 12 preaxial polydactyly families and refinement of the localisation of the gene responsible to a 1.9 cM region on chromosome 7q36. J Med Genet (1999) 1.35
Influence of cranioplasty on postural blood flow regulation, cerebrovascular reserve capacity, and cerebral glucose metabolism. J Neurosurg (2000) 1.35
Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study. J Neurol Neurosurg Psychiatry (2004) 1.35
Preservation of diffusion tensor properties during spatial normalization by use of tensor imaging and fibre tracking on a normal brain database. Phys Med Biol (2007) 1.32
Laparoscopic surgery complications associated with trocar tip design: review of literature and own results. J Laparoendosc Adv Surg Tech A (1999) 1.32
An assessment of protein secondary structure prediction methods based on amino acid sequence. Biochim Biophys Acta (1976) 1.28
Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly. J Med Genet (2005) 1.27
High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study. J Neural Transm (Vienna) (2004) 1.26
Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis. J Neurol (2010) 1.26
Serum parathyroid hormone is associated with increased mortality independent of 25-hydroxy vitamin d status, bone mass, and renal function in the frail and very old: a cohort study. J Clin Endocrinol Metab (2004) 1.25
Accidental inoculation blastomycosis. Cutis (1977) 1.25
The primary erythermalgia-susceptibility gene is located on chromosome 2q31-32. Am J Hum Genet (2001) 1.24
A dynein mutation attenuates motor neuron degeneration in SOD1(G93A) mice. Exp Neurol (2006) 1.23
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology (2003) 1.22
Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells. Exp Neurol (2001) 1.21
Starnberg trial on epidemiology of Parkinsonism and hypertension in the elderly. Prevalence of Parkinson's disease and related disorders assessed by a door-to-door survey of inhabitants older than 65 years. Arch Neurol (1995) 1.21
Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe. Hum Mutat (2003) 1.20
An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Mol Psychiatry (2012) 1.18
In vivo imaging of activated microglia using [11C]PK11195 and positron emission tomography in patients after ischemic stroke. Neuroreport (2000) 1.18
Deletion of exon 18 is a frequent mutation in glycogen storage disease type II. Biochem Biophys Res Commun (1994) 1.17
Demonstration of acid-fast rods in sarcoidosis. Am Rev Respir Dis (1970) 1.16
Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration. J Neural Transm (Vienna) (2004) 1.15
The effect of a single base pair deletion (delta T525) and a C1634T missense mutation (pro545leu) on the expression of lysosomal alpha-glucosidase in patients with glycogen storage disease type II. Hum Mol Genet (1994) 1.14