| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
New azole antifungals. 3. Synthesis and antifungal activity of 3-substituted-4(3H)-quinazolinones.
|
J Med Chem
|
1998
|
2.26
|
|
2
|
Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines.
|
J Med Chem
|
2001
|
1.41
|
|
3
|
Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial.
|
Ann Intern Med
|
2000
|
1.09
|
|
4
|
Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization.
|
Br J Pharmacol
|
2012
|
1.07
|
|
5
|
[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.
|
J Med Chem
|
1994
|
0.89
|
|
6
|
Inhibition of rat liver microsomal fatty acid chain elongation by gemfibrozil in vitro.
|
FEBS Lett
|
1992
|
0.88
|
|
7
|
Relationship between plasma lipids and palmitoyl-CoA hydrolase and synthetase activities with peroxisomal proliferation in rats treated with fibrates.
|
Br J Pharmacol
|
1994
|
0.87
|
|
8
|
Differential inhibition of long-chain acyl-CoA hydrolases by hypolipidemic drugs in vitro.
|
Biochem Pharmacol
|
1992
|
0.87
|
|
9
|
Fibrates modify rat hepatic fatty acid chain elongation and desaturation in vitro.
|
Biochem Pharmacol
|
1993
|
0.86
|
|
10
|
Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock.
|
Br J Pharmacol
|
1996
|
0.86
|
|
11
|
Long-term protective effect of UR-12670 after warm renal ischemia in uninephrectomized rats.
|
Kidney Int
|
1999
|
0.85
|
|
12
|
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation.
|
Br J Pharmacol
|
1995
|
0.85
|
|
13
|
Cytosolic lipogenic enzymes: effect of fibric acid derivatives in vitro.
|
Life Sci
|
1993
|
0.84
|
|
14
|
Gemfibrozil modifies acyl composition of liver microsomal phospholipids from guinea-pigs without promoting peroxisomal proliferation.
|
Biochem Pharmacol
|
1993
|
0.84
|
|
15
|
Defense related phytohormones regulation in arbuscular mycorrhizal symbioses depends on the partner genotypes.
|
J Chem Ecol
|
2014
|
0.83
|
|
16
|
Differential effects of fibrates on the acyl composition of microsomal phospholipids in rats.
|
Br J Pharmacol
|
1995
|
0.83
|
|
17
|
Influence of lipid profile and fatty acid composition on the oxidation behavior of rat and guinea pig low density lipoprotein.
|
Comp Biochem Physiol B Biochem Mol Biol
|
1998
|
0.83
|
|
18
|
Protective effect of UR-12670 on chronic nephropathy induced by warm ischaemia in ageing uninephrectomized rats.
|
Nephrol Dial Transplant
|
2001
|
0.83
|
|
19
|
Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity.
|
J Med Chem
|
2001
|
0.83
|
|
20
|
Disubstituted tetrahydrofurans and dioxolanes and PAF antagonists.
|
J Med Chem
|
1991
|
0.82
|
|
21
|
In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1.
|
Inflamm Res
|
2000
|
0.82
|
|
22
|
In vitro effect of clofibric acid derivatives on rat hepatic microsomal electron transport chains.
|
Biochem Pharmacol
|
1991
|
0.82
|
|
23
|
Cold ischemia in the absence of alloreactivity induces chronic transplant nephropathy through a process mediated by the platelet-activating factor.
|
Transplantation
|
2000
|
0.81
|
|
24
|
Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid.
|
Mol Pharmacol
|
1999
|
0.81
|
|
25
|
Synthesis and structure-activity relationships of 1-acyl-4-((2-methyl-3-pyridyl)cyanomethyl)piperazines as PAF antagonists.
|
J Med Chem
|
1993
|
0.80
|
|
26
|
Effect of endotoxin and platelet-activating factor on rat vascular permeability: role of vasoactive mediators.
|
J Lipid Mediat Cell Signal
|
1997
|
0.79
|
|
27
|
New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol.
|
J Med Chem
|
1998
|
0.79
|
|
28
|
Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat.
|
Br J Pharmacol
|
2000
|
0.79
|
|
29
|
Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cells.
|
Br J Pharmacol
|
2001
|
0.78
|
|
30
|
Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells.
|
J Lipid Res
|
2001
|
0.78
|
|
31
|
Decreased susceptibility to copper-induced oxidation of rat-lipoproteins after fibrate treatment: influence of fatty acid composition.
|
Br J Pharmacol
|
1996
|
0.77
|
|
32
|
Different effects of fibrates on the microsomal fatty acid chain elongation and the acyl composition of phospholipids in guinea-pigs.
|
Br J Pharmacol
|
1995
|
0.76
|
|
33
|
The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis.
|
Br J Pharmacol
|
2012
|
0.76
|
|
34
|
Lipoprotein composition and oxidative modification during therapy with gemfibrozil and lovastatin in patients with combined hyperlipidaemia.
|
Br J Clin Pharmacol
|
1998
|
0.75
|
|
35
|
4-substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists.
|
J Med Chem
|
1992
|
0.75
|
|
36
|
Effects of a new platelet-activating factor antagonist, UR-12670, on several endotoxic shock markers in rats.
|
Drugs Exp Clin Res
|
1997
|
0.75
|
|
37
|
UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model.
|
Inflamm Res
|
2010
|
0.75
|
|
38
|
Design of potent linear PAF antagonists.
|
J Med Chem
|
1991
|
0.75
|
|
39
|
(Pyridylcyanomethyl)piperazines as orally active PAF antagonists.
|
J Med Chem
|
1992
|
0.75
|
|
40
|
Alternative binding assay of GP IIb/IIIa antagonists with a nonradioactive labeling method of platelets.
|
Thromb Res
|
2001
|
0.75
|
|
41
|
In vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity.
|
Arzneimittelforschung
|
1992
|
0.75
|
|
42
|
Design, synthesis, and structure-activity relationship studies of novel 1-[(1-acyl-4-piperidyl)methyl]-1H-2- methylimidazo[4,5-c]pyridine derivatives as potent, orally active platelet-activating factor antagonists.
|
J Med Chem
|
1996
|
0.75
|
|
43
|
In vitro study of caffeic acid-bovine serum albumin interaction.
|
Eur J Drug Metab Pharmacokinet
|
1988
|
0.75
|
|
44
|
Characterization of [3H]apafant binding to PAF receptor on rabbit platelet membranes: a comparison of a microplate filtration system and a standard method.
|
J Pharmacol Toxicol Methods
|
1996
|
0.75
|