PubRank

M L Sinnott

Author PubWeight™ 41.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The mechanism of action of beta-galactosidase. Effect of aglycone nature and -deuterium substitution on the hydrolysis of aryl galactosides. Biochem J 1973 1.91
2 The effect of methanol and dioxan on the rates of the beta-galactosidase-catalysed hydrolyses of some beta-D-galactrophyranosides: rate-limiting degalactosylation. The ph-dependence of galactosylation and degalactosylation. Biochem J 1973 1.68
3 The necessity of magnesium cation for acid assistance aglycone departure in catalysis by Escherichia coli (lacZ) beta-galactosidase. Biochem J 1978 1.20
4 The beta-galactosidase-catalysed hydrolyses of beta-d-galactopyranosyl pyridium salts. Rate-limiting generation of an enzyme-bound galactopyranosyl cation in a process dependent only on aglycone acidity. Biochem J 1974 1.18
5 Affinity labelling with a deaminatively generated carbonium ion. Kinetics and stoicheiometry of the alkylation of methionine-500 of the lacZ beta-galactosidase of Escherichia coli by beta-D-galactopyranosylmethyl-p-nitrophenyltriazene. Biochem J 1978 1.16
6 The interaction of 1-fluoro-D-glucopyranosyl fluoride with glucosidases. Biochem J 1991 1.10
7 Key residues in subsite F play a critical role in the activity of Pseudomonas fluorescens subspecies cellulosa xylanase A against xylooligosaccharides but not against highly polymeric substrates such as xylan. J Biol Chem 1997 1.09
8 -galactosidase-catalysed hydrolysis of -D-galactopyranosyl azide. Biochem J 1971 1.09
9 Ions, ion-pairs and catalysis by the lacZ beta-galactosidase of Escherichia coli. FEBS Lett 1978 1.06
10 The catalytic consequences of experimental evolution. Transition-state structure during catalysis by the evolved beta-galactosidases of Escherichia coli (ebg enzymes) changed by a single mutational event. Biochem J 1989 1.02
11 Turnover of beta-galactosidase in fibroblasts from patients with genetically different types of beta-galactosidase deficiency. Biochem J 1981 0.99
12 Methionine 500, the site of covalent attachment of an active site-directed reagent of beta-galactosidase. J Biol Chem 1978 0.97
13 Purification and mechanistic properties of an extracellular alpha-L-arabinofuranosidase from Monilinia fructigena. Biochem J 1987 0.97
14 The catalytic consequences of experimental evolution. Studies on the subunit structure of the second (ebg) beta-galactosidase of Escherichia coli, and on catalysis by ebgab, an experimental evolvant containing two amino acid substitutions. Biochem J 1992 0.96
15 The role of magnesium ions in beta-galactosidase hydrolyses. Studies on charge and shape of the beta-galactopyranosyl binding site. Biochem J 1973 0.96
16 Lysozyme-catalysed hydrolysis of some beta-aryl di-N-acetylchitobiosides. Biochem J 1967 0.96
17 Large changes of transition-state structure during experimental evolution of an enzyme. Biochem J 1993 0.95
18 A solvent-isotope-effect study of proton transfer during catalysis by Escherichia coli (lacZ) beta-galactosidase. Biochem J 1990 0.95
19 Specific inactivation of lysosomal glycosidases in living fibroblasts by the corresponding glycosylmethyl-p-nitrophenyltriazenes. Biochem J 1980 0.94
20 A kinetic-isotope-effect study of catalysis by Vibrio cholerae neuraminidase. Biochem J 1993 0.92
21 Lignocellulose degradation by Phanerochaete chrysosporium: purification and characterization of the main alpha-galactosidase. Biochem J 1999 0.91
22 Goat liver beta-mannosidases: molecular properties, inhibition and inactivation of the lysosomal and nonlysosomal forms. Enzyme 1985 0.90
23 Investigation of alpha-deuterium kinetic isotope effects on the purine nucleoside phosphorylase reaction by the equilibrium-perturbation technique. Biochem J 1989 0.89
24 Effects of deuterium substitution alpha and beta to the reaction centre, 18O substitution in the leaving group, and aglycone acidity on hydrolyses of aryl glucosides and glucosyl pyridinium ions by yeast alpha-glucosidase. A probable failure of the antiperiplanar-lone-pair hypothesis in glycosidase catalysis. Biochem J 1985 0.88
25 Identification of Asp-130 as the catalytic nucleophile in the main alpha-galactosidase from Phanerochaete chrysosporium, a family 27 glycosyl hydrolase. Biochemistry 2000 0.87
26 Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/ A224H/L225V/T226A/D262G mutant. Biochem J 2001 0.86
27 One-proton catalysis by the alpha-L-arabinofuranosidase III of Monilinia fructigena. Biochem J 1988 0.83
28 Phanerochaete chrysosporium and its natural substrate. FEMS Microbiol Rev 1994 0.82
29 Hydrolyses of alpha- and beta-cellobiosyl fluorides by cellobiohydrolases of Trichoderma reesei. Biochem J 1993 0.82
30 On the antiperiplanar lone pair hypothesis and its application to catalysis by glycosidases. Biochem J 1984 0.82
31 Substrate specificity in glycoside hydrolase family 10. Tyrosine 87 and leucine 314 play a pivotal role in discriminating between glucose and xylose binding in the proximal active site of Pseudomonas cellulosa xylanase 10A. J Biol Chem 2000 0.82
32 Affinity labeling via deamination reactions. CRC Crit Rev Biochem 1982 0.81
33 Hydrolyses of alpha- and beta-cellobiosyl fluorides by Cel6A (cellobiohydrolase II) of Trichoderma reesei and Humicola insolens. Biochem J 2000 0.80
34 Catalysis by the large subunit of the second beta-galactosidase of Escherichia coli in the absence of the small subunit. Biochem J 1995 0.80
35 Dependence upon pH of steady-state parameters for the beta-galactosidase-catalysed hydrolyses of beta-D-galactopyranosyl derivatives of different chemical types. Eur J Biochem 1978 0.80
36 Interaction of the lacZ beta-galactosidase of Escherichia coli with some beta-D-galactopyranoside competitive inhibitors. Biochem J 1979 0.80
37 Catalytic consequences of experimental evolution: catalysis by a 'third-generation' evolvant of the second beta-galactosidase of Escherichia coli, ebgabcde, and by ebgabcd, a 'second-generation' evolvant containing two supposedly 'kinetically silent' mutations. Biochem J 1995 0.78
38 Inhibition of the alpha-L-arabinofuranosidase III of Monilinia fructigena by 1,4-dideoxy-1,4-imino-L-threitol and 1,4-dideoxy-1,4-imino-L-arabinitol. Biochem J 1990 0.78
39 Polarimetry and 13C n.m.r. show that the hydrolyses of beta-D-glucopyranosyl fluoride by beta(1-->3)-glucanases from Phanerochaete chrysosporium and Sporotrichum dimorphosporum have opposite stereochemistries. Biochem J 1993 0.77
40 Hydrolysis of glycosylpyridinium ions by anomeric-configuration-inverting glycosidases. Carbohydr Res 1993 0.77
41 Competitive inhibition of the inverting beta-xylosidase of Bacillus pumilus 12 by monosaccharide derivatives of different structural and conformational types. A possible natural substrate. Biochem J 1983 0.75
42 beta-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. Biochem J 1991 0.75
43 Salmonella typhimurium neuraminidase acts with inversion of configuration. Biochem J 1993 0.75
44 Larger increases in sensitivity to paracatalytic inactivation than in catalytic competence during experimental evolution of the second beta-galactosidase of Escherichia coli. Biochem J 1997 0.75
45 A new affinity ligand for the isolation of a single 'feruloyl esterase' (FAE-III) from Aspergillus niger. Bioorg Med Chem 2000 0.75
46 Inactivation of GM1-ganglioside beta-galactosidase by a specific inhibitor: a model for ganglioside storage disease. Ann Neurol 1987 0.75
47 Definition of the substrate specificity of the 'sensing' xylanase of Streptomyces cyaneus using xylooligosaccharide and cellooligosaccharide glycosides of 3,4-dinitrophenol. J Biotechnol 1997 0.75