A J Dorner

Author PubWeight™ 80.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature 1981 16.61
2 In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysate. J Virol 1984 4.54
3 Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals. Nucleic Acids Res 1984 4.19
4 Determinants for receptor interaction and cell killing on the avian retrovirus glycoprotein gp85. Cell 1986 3.80
5 Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol Cell Biol 1997 3.70
6 Identification of the initiation site of poliovirus polyprotein synthesis. J Virol 1982 3.62
7 Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins. J Biol Chem 1997 3.22
8 Molecular basis of host range variation in avian retroviruses. J Virol 1985 2.19
9 Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J Biol Chem 1988 1.96
10 Cleavage sites within the poliovirus capsid protein precursors. J Virol 1982 1.95
11 The fate of VPg during in vitro translation of poliovirus RNA. FEBS Lett 1981 1.74
12 Identification of a poliovirus neutralization epitope through use of neutralizing antiserum raised against a purified viral structural protein. Virology 1983 1.61
13 Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J Immunol 1996 1.60
14 Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells. Mol Cell Biol 1989 1.36
15 Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling. Pharmacogenomics J 2001 1.34
16 Regulation of PACE propeptide-processing activity: requirement for a post-endoplasmic reticulum compartment and autoproteolytic activation. Proc Natl Acad Sci U S A 1992 1.23
17 Defining mechanisms of action of interleukin-11 on the progression of radiation-induced oral mucositis in hamsters. Oral Oncol 2000 1.22
18 The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII. J Biol Chem 1991 1.21
19 Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions. J Clin Invest 1999 1.21
20 Hematopoietic, immunomodulatory and epithelial effects of interleukin-11. Leukemia 1999 1.16
21 High level synthesis of immunoglobulins in Chinese hamster ovary cells. J Immunol 1990 1.16
22 Protein-linked RNA of poliovirus is competent to form an initiation complex of translation in vitro. Nature 1980 1.13
23 IL-11 regulates macrophage effector function through the inhibition of nuclear factor-kappaB. J Immunol 1997 1.12
24 Analysis of synthesis, processing, and secretion of proteins expressed in mammalian cells. Methods Enzymol 1990 1.10
25 The structure of poliovirus replicative form. Nucleic Acids Res 1980 1.07
26 The importance of N- and O-linked oligosaccharides for the biosynthesis and in vitro and in vivo biologic activities of erythropoietin. Blood 1991 1.04
27 Molecular effects of recombinant human interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease. Lab Invest 1998 0.98
28 Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung. Pharmacogenomics J 2006 0.97
29 Interleukin-11 modulates Th1/Th2 cytokine production from activated CD4+ T cells. J Interferon Cytokine Res 2001 0.97
30 Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage: reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis. Osteoarthritis Cartilage 2009 0.96
31 Interleukin-11 induces intestinal epithelial cell growth arrest through effects on retinoblastoma protein phosphorylation. Am J Pathol 1996 0.94
32 Conversion of pre-proparathyroid hormone to proparathyroid hormone by dog pancreatic microsomes. Biochemistry 1978 0.93
33 Interleukin-11 reduces T-cell-dependent experimental liver injury in mice. Hepatology 1999 0.93
34 Interleukin-11. A gp130 cytokine. Ann N Y Acad Sci 1998 0.87
35 In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response. Clin Exp Allergy 2008 0.83
36 The therapeutic utility of Interleukin-11 in the treatment of inflammatory disease. Expert Opin Investig Drugs 1998 0.83
37 Formation in vitro of membrane-bound polysomes containing parathyroid hormone messenger ribonucleic acid. Biochemistry 1979 0.82
38 von Willebrand factor elevates plasma factor VIII without induction of factor VIII messenger RNA in the liver. Blood 1999 0.82
39 Protective effect of rhIL-11 in a murine model of acetaminophen-induced hepatotoxicity. Toxicol Pathol 2001 0.81
40 Dose-dependent and schedule-dependent effects of interleukin-12 on antigen-specific CD8 responses. J Interferon Cytokine Res 2000 0.79
41 A CTL assay requiring only 150 microliter of mouse blood. J Immunol Methods 2000 0.79
42 Pharmacogenomic analysis of rhIL-11 treatment in the HLA-B27 rat model of inflammatory bowel disease. Pharmacogenomics J 2002 0.78
43 IL-12-Dependent enhancement of CTL response to weak class I-restricted peptide immunogens requires coimmunization with T helper cell immunogens. Clin Immunol 2000 0.78
44 Recombinant human interleukin-11 does not affect functions of purified human neutrophils in vitro. J Interferon Cytokine Res 1998 0.77
45 Experience with voluntary and required genomic data submissions to the FDA: summary report from track 1 of the third FDA-DIA-PWG-PhRMA-BIO pharmacogenomics workshop. Pharmacogenomics J 2006 0.75
46 Subcutaneous or oral administration of rhIL-11 modulated the contact hypersensitivity response. Cytokine 2000 0.75
47 Mechanistic toxicogenomic analysis of WAY-144122 administration in Sprague-Dawley rats. Toxicol Appl Pharmacol 2004 0.75
48 Immune response enhancement by in vivo administration of B7.2Ig, a soluble costimulatory protein. Clin Immunol 1999 0.75
49 In vivo absorption properties of orally administered recombinant human interleukin-11. Pharm Res 2000 0.75