Published in Protein Sci on November 01, 1999
CASTp: Computed Atlas of Surface Topography of proteins. Nucleic Acids Res (2003) 4.93
Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration. Protein Sci (2008) 1.44
Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature. EMBO J (2002) 1.20
Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C). EMBO J (2001) 0.98
Genetic and biochemical characterization of a novel umuD mutation: insights into a mechanism for UmuD self-cleavage. J Bacteriol (2001) 0.89
The Roles of UmuD in Regulating Mutagenesis. J Nucleic Acids (2010) 0.82
Multiple strategies for translesion synthesis in bacteria. Cells (2012) 0.80
Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A (1991) 119.63
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng (1997) 38.38
On the size of the active site in proteases. I. Papain. Biochem Biophys Res Commun (1967) 18.32
Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design. Protein Sci (1998) 7.03
PROMOTIF--a program to identify and analyze structural motifs in proteins. Protein Sci (1996) 6.76
RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation. Proc Natl Acad Sci U S A (1988) 4.41
RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis. Proc Natl Acad Sci U S A (1988) 4.12
Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor. Nature (1998) 3.37
Lysine-156 and serine-119 are required for LexA repressor cleavage: a possible mechanism. Proc Natl Acad Sci U S A (1987) 3.04
Families of serine peptidases. Methods Enzymol (1994) 2.94
Occluded molecular surface: analysis of protein packing. J Mol Recognit (1997) 1.76
Structure of the UmuD' protein and its regulation in response to DNA damage. Nature (1996) 1.66
Catalytic hydroxyl/amine dyads within serine proteases. Trends Biochem Sci (1997) 1.38
SOS-regulated proteins in translesion DNA synthesis and mutagenesis. Trends Biochem Sci (1995) 1.34
Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis. Nat Struct Biol (1997) 1.30
A serine and a lysine residue implicated in the catalytic mechanism of the Escherichia coli leader peptidase. J Biol Chem (1993) 1.12
Intermolecular cleavage by UmuD-like enzymes: identification of residues required for cleavage and substrate specificity. J Mol Biol (1999) 1.09
Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase. J Biol Chem (1997) 1.02
In addition to SEC11, a newly identified gene, SPC3, is essential for signal peptidase activity in the yeast endoplasmic reticulum. J Biol Chem (1997) 0.96
Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor. Nature (1998) 3.37
Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs. Nat Struct Biol (2001) 2.79
Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex. Nature (2000) 2.21
Structural and biochemical characterization of the type III secretion chaperones CesT and SigE. Nat Struct Biol (2001) 2.04
Calcium-binding sites in proteins: a structural perspective. Adv Protein Chem (1991) 1.86
Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell (2001) 1.84
Crystal structure of the class D beta-lactamase OXA-10. Nat Struct Biol (2000) 1.72
The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation. Biochemistry (2000) 1.50
Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion. Mol Microbiol (1999) 1.49
The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. Structure (1994) 1.41
The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target. Pharmacol Ther (2000) 1.28
Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin. Curr Biol (2000) 1.24
Structure and characterization of AgfB from Salmonella enteritidis thin aggregative fimbriae. J Mol Biol (2001) 1.14
Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies. Biochemistry (2001) 1.08
The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases. Biochemistry (2000) 1.08
Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP. J Biol Chem (2000) 1.07
Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase. Nat Struct Biol (2001) 1.06
Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,). Biochemistry (2000) 1.03
Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase. J Biol Chem (1997) 1.02
The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization. Biochemistry (2001) 0.99
Analysis of the role of antibody-dependent cellular cytotoxic antibody activity in murine neonatal herpes simplex virus infection with antibodies to synthetic peptides of glycoprotein D and monoclonal antibodies to glycoprotein B. J Clin Invest (1990) 0.92
The role of the conserved box E residues in the active site of the Escherichia coli type I signal peptidase. J Biol Chem (2000) 0.90
Effect of divalent metal cations on the dimerization of OXA-10 and -14 class D beta-lactamases from Pseudomonas aeruginosa. Biochemistry (2001) 0.86
Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues. Biochemistry (1992) 0.86
Catalysis and binding in L-ribulose-5-phosphate 4-epimerase: a comparison with L-fuculose-1-phosphate aldolase. Biochemistry (2001) 0.86
Mutational evidence of transition state stabilization by serine 88 in Escherichia coli type I signal peptidase. Biochemistry (2000) 0.84
Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II. Biochemistry (1991) 0.83
4Ca2+.troponin C forms dimers in solution at neutral pH that dissociate upon binding various peptides: small-angle X-ray scattering studies of peptide-induced structural changes. Biochemistry (1992) 0.81