PubRank

L H Tsai

Author PubWeight™ 96.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 1996 8.41
2 Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 1999 5.53
3 A decade of CDK5. Nat Rev Mol Cell Biol 2001 5.24
4 A family of human cdc2-related protein kinases. EMBO J 1992 4.96
5 A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. Mol Cell Biol 1996 4.61
6 Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 1995 4.48
7 Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 2000 4.31
8 Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature 1992 4.21
9 Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature 1999 3.50
10 NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron 2000 3.45
11 Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 1997 2.96
12 Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron 2000 2.82
13 Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol 2000 2.81
14 Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci U S A 1995 2.70
15 The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev 1996 2.59
16 Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science 1992 2.13
17 The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature 1998 2.01
18 p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci 2001 1.87
19 Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. Chem Biol 2000 1.71
20 p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. J Biol Chem 1998 1.63
21 Structure and regulation of the CDK5-p25(nck5a) complex. Mol Cell 2001 1.57
22 Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2. J Biol Chem 2000 1.31
23 Cdk5 on the brain. Cell Growth Differ 2001 1.21
24 The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc Natl Acad Sci U S A 1996 1.15
25 The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. Genes Dev 1997 1.09
26 A novel disruption of cortical development in p35(-/-) mice distinct from reeler. J Comp Neurol 1998 1.07
27 Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase. Proc Natl Acad Sci U S A 1999 1.07
28 Abnormal morphological and functional organization of the hippocampus in a p35 mutant model of cortical dysplasia associated with spontaneous seizures. J Neurosci 2001 1.07
29 Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase. Curr Biol 2000 1.06
30 Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse. J Neurocytol 1997 0.93
31 The early effect of pelvic floor muscle exercise after transurethral prostatectomy. J Urol 1998 0.91
32 Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5. J Neurochem 1996 0.91
33 Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells. J Cell Physiol 2001 0.90
34 Callosal axon guidance defects in p35(-/-) mice. J Comp Neurol 1999 0.88
35 Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1. J Biomol NMR 2000 0.88
36 The role of the p35/cdk5 kinase in cortical development. Results Probl Cell Differ 2000 0.88
37 The cyclin-dependent kinase family. Cold Spring Harb Symp Quant Biol 1991 0.87
38 Cyclin E-p27 opposition and regulation of the G1 phase of the cell cycle in the murine neocortical PVE: a quantitative analysis of mRNA in situ hybridization. Cereb Cortex 1999 0.87
39 Synaptic localization of p39, a neuronal activator of cdk5. Neuroreport 2000 0.87
40 Characterization of carbapenem-nonsusceptible Klebsiella pneumoniae bloodstream isolates at a Taiwanese hospital: clinical impacts of lowered breakpoints for carbapenems. Eur J Clin Microbiol Infect Dis 2012 0.85
41 Bloodstream infections caused by IMP-8-producing Enterobacteriaceae isolates: the need for clinical laboratory detection of metallo-β-lactamases? Eur J Clin Microbiol Infect Dis 2012 0.85
42 Cell cycle control. Adv Exp Med Biol 2000 0.82
43 Activity and regulation of p35/Cdk5 kinase complex. Methods Enzymol 2000 0.78
44 Neuroscience. A kinase to dampen the effects of cocaine? Science 2001 0.77
45 Vasoactive intestinal polypeptide provokes acetylcholine release from the myenteric plexus. Am J Physiol 1986 0.77
46 Protective effect of excitatory amino acids on cold-restraint stress-induced gastric ulcers in mice: role of cyclic nucleotides. Dig Dis Sci 2001 0.76
47 Backbone 1H, 15N, and 13C resonance assignments of ARPP-19. J Biomol NMR 2001 0.76
48 Cdk5 at the junction. Nat Neurosci 2001 0.75
49 Pharmacological characterization of alpha 2-adrenoceptors in isolated jejunum of rabbits. Chin J Physiol 1992 0.75
50 Influence of whole-body mechanical vibration on altitude convulsion threshold. Chin J Physiol 1978 0.75
51 Inactivation of Formosan snake venoms in vitro by the crude extract of Aristolochia radix. Taiwan Yi Xue Hui Za Zhi 1975 0.75
52 Whole-body mechanical vibration and incidence of decompression-induced pulmonary hemorrhage in mice. Taiwan Yi Xue Hui Za Zhi 1982 0.75
53 Immunobiologic, cytogenetic and drug response features of a newly established cell line (SCRC-1) from renal small cell carcinoma. J Urol 2000 0.75