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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999 17.72
2 A role for ghrelin in the central regulation of feeding. Nature 2001 8.12
3 Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochem Biophys Res Commun 2001 2.13
4 Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors. Circulation 2001 1.86
5 Identification of human beta-defensin-2 in respiratory tract and plasma and its increase in bacterial pneumonia. Biochem Biophys Res Commun 1998 1.29
6 Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus. Neurosci Lett 2002 1.23
7 Central effects of neuromedin U in the regulation of energy homeostasis. Biochem Biophys Res Commun 2000 1.15
8 Ghrelin in neonatal rats: distribution in stomach and its possible role. J Endocrinol 2002 1.03
9 Differences in MHC class I self peptide repertoires among HLA-A2 subtypes. J Immunol 1995 1.02
10 Comprehensive analysis of HLA genes in Takayasu arteritis in Japan. Int J Cardiol 1996 1.01
11 Purification and identification of neuromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3). Biochem Biophys Res Commun 2000 0.98
12 Involvement of dendritic cells in sarcoidosis. Thorax 2004 0.96
13 Spermatic cord metastases from gastric cancer with elevation of serum hCG-beta: a case report. Jpn J Clin Oncol 2000 0.96
14 Identification of hBD-3 in respiratory tract and serum: the increase in pneumonia. Eur Respir J 2006 0.95
15 Familial leptomeningeal amyloidosis with a transthyretin variant Asp18Gly representing repeated subarachnoid haemorrhages with superficial siderosis. J Neurol Neurosurg Psychiatry 2004 0.90
16 Cloning and characterization of a cDNA encoding a precursor for human uroguanylin. Biochem Biophys Res Commun 1996 0.90
17 Isolation and sequence determination of 6- and 8-kDa precursors of human neutrophil peptides from bone marrow, plasma and peripheral blood neutrophils. Biochem Biophys Res Commun 1995 0.87
18 Tissue distribution, cellular source, and structural analysis of rat immunoreactive uroguanylin. Endocrinology 1998 0.87
19 Down regulation of the prepro-orexin gene expression in genetically obese mice. Brain Res Mol Brain Res 1999 0.87
20 Polymorphisms in the 5'-flanking region of tumor necrosis factor-alpha gene in patients with rheumatoid arthritis. Tissue Antigens 1999 0.85
21 Widespread distribution of orexin in rat brain and its regulation upon fasting. Biochem Biophys Res Commun 1999 0.84
22 Galanin-like peptide promotes feeding behaviour via activation of orexinergic neurones in the rat lateral hypothalamus. J Neuroendocrinol 2006 0.84
23 Urine and plasma levels of uroguanylin and its molecular forms in renal diseases. Kidney Int 1997 0.83
24 Nucleotide sequence and expression of rat beta-defensin-1: its significance in diabetic rodent models. Nephron 2001 0.82
25 High peroxidative susceptibility of fish oil polyunsaturated fatty acid in cultured rat hepatocytes. Toxicol Appl Pharmacol 1994 0.81
26 A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells. Pathol Int 1999 0.81
27 Determination of free hydroxyproline and proline in human serum by high-performance liquid chromatography using 4-(5,6-dimethoxy-2-phthalimidinyl)phenylsulfonyl chloride as a pre-column fluorescent labelling reagent. Analyst 1995 0.81
28 Recombinant granulocyte colony-stimulating factor induces production of human neutrophil peptides in lung cancer patients with neutropenia. Regul Pept 2000 0.81
29 Acute incremental exercise decreases plasma ghrelin level in healthy men. Horm Metab Res 2007 0.80
30 Identification of 10-kDa proguanylin as a major guanylin molecule in human intestine and plasma and its increase in renal insufficiency. Biochem Biophys Res Commun 1994 0.80
31 On the mechanism of action of luteinizing hormone-releasing factor and prolactin release inhibiting factor. Endocrinology 1973 0.80
32 Jh gene sequence analysis in a patient with Waldenström's macroglobulinaemia with subsequent development of immunoblastic lymphoma. Clin Mol Pathol 1995 0.79
33 Characterization of the gammac chain among 27 unrelated Japanese patients with X-linked severe combined immunodeficiency (X-SCID). Hum Genet 2000 0.79
34 Effects of simultaneous rhG-CSF and methylprednisolone "pulse" therapy on hepatitis A virus-associated haemophagocytic syndrome. Eur J Haematol 1995 0.79
35 Characterization of orexin-A and orexin-B in the microdissected rat brain nuclei and their contents in two obese rat models. Neurosci Lett 1999 0.79
36 Detection of a new TIGR gene mutation in a Japanese family with primary open angle glaucoma. Jpn J Ophthalmol 1999 0.79
37 Human herpesvirus-6 encephalitis after bone marrow transplantation: magnetic resonance imaging could identify the involved sites of encephalitis. Eur J Haematol 1998 0.79
38 Neuropeptide W is present in antral G cells of rat, mouse, and human stomach. J Endocrinol 2006 0.78
39 Metabolic features of rats resistant to a high-fat diet. Obes Res Clin Pract 2013 0.78
40 Determination of total hydroxyproline and proline in human serum and urine by HPLC with fluorescence detection. Biol Pharm Bull 1996 0.78
41 Uroguanylin level in umbilical cord blood. Pediatr Int 2001 0.78
42 Effective simultaneous rhG-CSF and methylprednisolone "pulse" therapy in agranulocytosis associated with systemic lupus erythematosus. Am J Hematol 1994 0.77
43 Significance of antibodies to streptococcal M protein in psoriatic arthritis and their association with HLA-A*0207. Tissue Antigens 1996 0.77
44 [Thoracoscopic extended thymectomy in conjunction with a collar incision of the neck for cases of myasthenia gravis]. Kyobu Geka 1996 0.76
45 [Diagnosis and follow-up of ovarian cancer by a combination assay of serum sialyl SSEA-1 antigen and CA125 levels]. Nihon Gan Chiryo Gakkai Shi 1989 0.76
46 [A study of defensins in bronchoalveolar lavage fluid in patients with diffuse panbronchiolitis]. Kansenshogaku Zasshi 1995 0.76
47 A case of late onset cardiac amyloidosis with a new transthyretin variant (lysine 92). Hum Pathol 2001 0.75
48 Ampullary somatostatinoma in a patient with von Recklinghausen's disease. J Gastroenterol 1996 0.75
49 [A role for orexins and melanin-concentrating hormone in the central regulation of feeding behavior]. Nihon Rinsho 2001 0.75
50 [Thoracoscopic surgery of lung tumors]. Nihon Kyobu Geka Gakkai Zasshi 1996 0.75
51 [Blood flow of grafted stomach for esophageal reconstruction using the doppler ultrasound method]. Rinsho Kyobu Geka 1981 0.75
52 Clinical evaluations of the tumor marker sialyl SSEA-1 antigen for clinical gynecological disease. Gynecol Obstet Invest 1990 0.75
53 [Anastomotic technic of reconstruction using stomach after total esophagectomy (ante-thoracic route)]. Rinsho Kyobu Geka 1981 0.75
54 [A kinesiologic study on the slow stiff opening of the fingers in cervical cord lesions--particularly in cervical spondylotic myelopathy (author's transl)]. Nihon Seikeigeka Gakkai Zasshi 1980 0.75
55 CO 2 laser conization for cervical intraepithelial neoplasia: a comparison with cold knife conization during pregnancy. J Clin Laser Med Surg 1991 0.75
56 [Influence of pneumoperitoneum on respiratory function during urological laparoscopic surgery]. Nihon Hinyokika Gakkai Zasshi 1995 0.75
57 [The cytoimmunological effect of concomitant use of sizofiran (SPG) on advanced uterine cervical cancer treated with radiation]. Nihon Gan Chiryo Gakkai Shi 1989 0.75
58 Differential diagnosis of ovarian cancer, benign ovarian tumor and endometriosis by a combination assay of serum sialyl SSEA-1 antigen and CA125 levels. Gynecol Obstet Invest 1990 0.75
59 [One-stage bilateral lung volume reduction surgery with median sternal incision for diffuse pulmonary emphysema]. Nihon Kyobu Geka Gakkai Zasshi 1997 0.75
60 [A comparison between CO2 laser conization and cold knife conization in clinical diagnosis of cervical intraepithelial neoplasia]. Nihon Sanka Fujinka Gakkai Zasshi 1989 0.75
61 Polymerase chain reaction-based HLA-A genotyping and its application to matching in kidney transplantation. Transplant Proc 1995 0.75
62 Fatal transfusion-associated graft-versus-host disease. Transfusion 1994 0.75
63 [Studies on pregnancy after CO2 laser conization for cervical intraepithelial neoplasia]. Nihon Gan Chiryo Gakkai Shi 1989 0.75
64 Benefit of simultaneous rhG-CSF and methylprednisolone 'pulse' therapy for methotrexate-induced bone marrow failure in rheumatoid arthritis. Int J Hematol 1997 0.75
65 [Fine structure of the ultracentrifuged central nervous tissue. (3)]. Nihon Seirigaku Zasshi 1967 0.75
66 [A case of advanced uterine cervical cancer responsive to continuous intra-arterial chemotherapy using an implanted drug delivery system]. Gan To Kagaku Ryoho 1989 0.75
67 [Studies of intra-arterial hypertensive chemotherapy with cisplatin and peplomycin in advanced cancer of the uterine cervix--suitable dose of angiotensin II determined by intra-arterial digital subtraction angiography]. Nihon Sanka Fujinka Gakkai Zasshi 1988 0.75
68 [Metastatic endometrial stromal sarcoma successfully treated by intra-arterial hypertension chemotherapy with CDDP and ADM]. Gan To Kagaku Ryoho 1990 0.75
69 Simultaneous determination of cholesterol and cholestanol in human serum by high-performance liquid chromatography using 3-(5,6-methylenedioxy-2-phthalimidyl)benzoyl azide as precolumn fluorescent labelling reagent. J Chromatogr 1993 0.75
70 Formol-dichromate fixative for electron microscopy. J Electron Microsc (Tokyo) 1966 0.75
71 [Studies on renal dysfunction after intra-arterial hypertensive chemotherapy (CDDP, PEP) for advanced cancer of the uterine cervix--serum.urinary alpha 1-microglobulin, beta 2-microglobulin and urinary lysozyme, albumin]. Nihon Sanka Fujinka Gakkai Zasshi 1990 0.75
72 [Effects and side effects of hypertensive intra-arterial chemotherapy (CDDP, PEP) in advanced cancer of the uterine cervix]. Gan To Kagaku Ryoho 1989 0.75
73 [Six-year experience with sonometrics of the prostate. I: Contribution of sonometrics to diagnosis]. Nihon Hinyokika Gakkai Zasshi 1986 0.75
74 [Reverse-Y cardioplasty for achalasia]. Rinsho Kyobu Geka 1983 0.75
75 [Early esophageal cancer]. Rinsho Kyobu Geka 1981 0.75