Published in Blood on January 01, 2000
Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol (2009) 9.41
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother (2008) 6.55
Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood (2000) 4.78
Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol Immunother (2010) 3.00
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function. Blood (2007) 2.65
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med (2010) 2.06
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes. PLoS One (2008) 1.92
Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology (2008) 1.41
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci. Int J Exp Pathol (2007) 1.39
Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5. J Exp Med (2012) 1.28
Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth. PLoS One (2009) 1.24
Cytomegalovirus MCK-2 controls mobilization and recruitment of myeloid progenitor cells to facilitate dissemination. Blood (2005) 1.15
Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine. Cancer Immunol Immunother (2012) 1.10
Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination. Cancer Immunol Immunother (2009) 1.08
Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res (2014) 1.06
Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells. J Immunol (2010) 1.04
Gammadelta T-cells: potential regulators of the post-burn inflammatory response. Burns (2008) 1.01
Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice. J Clin Invest (2011) 1.01
Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells. J Leukoc Biol (2012) 1.00
Advances in the development of cancer immunotherapies. Trends Immunol (2012) 0.96
Central role for interleukin-4 in regulating nitric oxide-mediated inhibition of T-cell proliferation and gamma interferon production in schistosomiasis. Infect Immun (2002) 0.93
Conditions that diminish myeloid-derived suppressor cell activities stimulate cross-protective immunity. Infect Immun (2008) 0.92
Administration of cyclophosphamide changes the immune profile of tumor-bearing mice. J Immunother (2010) 0.91
Injury-induced GR-1+ macrophage expansion and activation occurs independently of CD4 T-cell influence. Shock (2011) 0.89
Radiation combined with thermal injury induces immature myeloid cells. Shock (2012) 0.87
Myeloid-derived suppressor cells: a double-edged sword? Int J Exp Pathol (2011) 0.85
T Cell Stimulatory Effects of Korean Red Ginseng through Modulation of Myeloid-Derived Suppressor Cells. J Ginseng Res (2011) 0.85
Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination. Cancer Immunol Immunother (2009) 0.84
Enhanced T-cell-independent antitumor effect of cyclophosphamide combined with anti-CD40 mAb and CpG in mice. J Immunother (2011) 0.84
Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response. Oncoimmunology (2014) 0.84
Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS One (2014) 0.84
mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors. Sci Rep (2016) 0.84
Phenotype, development, and biological function of myeloid-derived suppressor cells. Oncoimmunology (2015) 0.80
Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide. Cell Immunol (2012) 0.80
Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor γ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. J Immunol (2015) 0.80
Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer. J Transl Med (2011) 0.78
Recovery of humoral immunity is critical for successful antiviral therapy in disseminated mouse adenovirus type 1 infection. Antimicrob Agents Chemother (2008) 0.78
Inducible nitric oxide synthase response and associated cytokine gene expression in the spleen of mice infected with Clonorchis sinensis. Parasitol Res (2015) 0.76
Immunostimulatory Effects of Melphalan and Usefulness in Adoptive Cell Therapy with Antitumor CD4+ T Cells. Crit Rev Immunol (2016) 0.75
Chemotherapy-induced myeloid suppressor cells and antitumor immunity: The Janus face of chemotherapy in immunomodulation. Oncoimmunology (2014) 0.75
Chemotherapeutic agent-mediated elimination of myeloid-derived suppressor cells. Oncoimmunology (2017) 0.75
Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol (1995) 2.68
Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J Exp Med (2001) 2.22
Antigen-specific T lymphocyte clones. I. Characterization of a T lymphocyte clone expressing antigen-specific suppressive activity. J Exp Med (1981) 2.10
Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur J Immunol (1992) 1.96
Use of cloned populations of mouse lymphocytes to analyze cellular differentiation. Cell (1981) 1.95
Inhibition of translation in eukaryotic systems by harringtonine. Eur J Biochem (1977) 1.87
Antigen-specific T lymphocyte clones. II. Purification and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells. J Exp Med (1981) 1.86
Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate. Microb Drug Resist (2001) 1.82
Cathepsin D in host stromal cells, but not in tumor cells, is associated with aggressive behavior in node-negative breast cancer. Hum Pathol (1996) 1.81
Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-alpha and IFN-gamma through a nitric oxide-dependent mechanism. Immunol Lett (1992) 1.65
The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system. Prog Neurobiol (1998) 1.53
An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem (2000) 1.52
[Relationship between T-cells subsets and prognostic markers in HIV-1-infected children]. Med Clin (Barc) (2001) 1.39
Induction of cyclooxygenase-2 on activated T lymphocytes: regulation of T cell activation by cyclooxygenase-2 inhibitors. J Immunol (1999) 1.36
Translation elongation factor 2 is part of the target for a new family of antifungals. Antimicrob Agents Chemother (1998) 1.30
Inhibition of nuclear factor kappaB activation by a virus-encoded IkappaB-like protein. J Biol Chem (1998) 1.30
Down-regulation by tumor necrosis factor-alpha of neutrophil cell surface expression of the sialophorin CD43 and the hyaluronate receptor CD44 through a proteolytic mechanism. Eur J Immunol (1991) 1.22
Activities of sordarins in murine histoplasmosis. Antimicrob Agents Chemother (1999) 1.21
Microcin 7: purification and properties. Biochem Biophys Res Commun (1984) 1.21
Cellular adhesion mediated by factor J, a complement inhibitor. Evidence for nucleolin involvement. J Biol Chem (1998) 1.21
Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha. J Biol Chem (2001) 1.19
A conformational epitope expressed upon association of CD3-epsilon with either CD3-delta or CD3-gamma is the main target for recognition by anti-CD3 monoclonal antibodies. J Immunol (1991) 1.16
Initiation of the polypeptide chain by reticulocyte cell-free systems. Survey of different inhibitors of translation. Eur J Biochem (1976) 1.15
The CD3-gamma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes. EMBO J (1991) 1.12
Intra-Golgi transport inhibition by megalomicin. J Biol Chem (1996) 1.11
Antigen-specific T lymphocyte clones. III. Papain splits purified T suppressor molecules into two functional domains. J Exp Med (1982) 1.08
Bombesin induces cyclooxygenase-2 expression through the activation of the nuclear factor of activated T cells and enhances cell migration in Caco-2 colon carcinoma cells. Oncogene (2006) 1.06
Trypanosoma cruzi-induced molecular mimicry and Chagas' disease. Curr Top Microbiol Immunol (2005) 1.01
Narciclasine: an antitumour alkaloid which blocks peptide bond formation by eukaryotic ribosomes. FEBS Lett (1975) 0.99
Alteration of macrophage function by a Trypanosoma cruzi membrane mucin. J Immunol (1997) 0.99
Cloning and DNA sequence analysis of a bacteriocin gene of Serratia marcescens. J Gen Microbiol (1992) 0.99
Dominant T- and B-cell epitopes in an autoantigen linked to Chagas' disease. J Clin Invest (2001) 0.98
An endoplasmic reticulum retention signal in the CD3 epsilon chain of the T-cell receptor. Nature (1992) 0.98
Ribosomal P-protein stalk function is targeted by sordarin antifungals. J Biol Chem (1998) 0.98
Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines. J Immunol (1994) 0.98
Opportunistic infections and organ-specific diseases in HIV-1-infected children: a cohort study (1990-2006). HIV Med (2009) 0.98
Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain. J Immunol (1995) 0.97
Tumor necrosis factor-alpha activation of NF-kappa B requires the phosphorylation of Ser-471 in the transactivation domain of c-Rel. J Biol Chem (2000) 0.97
Inhibitors of polypeptide elongation on yeast polysomes. J Antibiot (Tokyo) (1975) 0.97
Naïve and memory CD4+ T cells and T cell activation markers in HIV-1 infected children on HAART. Clin Exp Immunol (2001) 0.96
Early myeloid cells are high producers of nitric oxide upon CD40 plus IFN-gamma stimulation through a mechanism dependent on endogenous TNF-alpha and IL-1alpha. Eur J Immunol (2000) 0.96
Preserved immune system in long-term asymptomatic vertically HIV-1 infected children. Clin Exp Immunol (2003) 0.95
Cot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells. J Biol Chem (2001) 0.95
Anaemia in advanced chronic fasciolosis. Acta Trop (2008) 0.93
Bruceantin, a novel inhibitor of peptide bond formation. Biochim Biophys Acta (1978) 0.92
Megalomicin inhibits HIV-1 replication and interferes with gp160 processing. Virology (1997) 0.92
Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: role of tumor necrosis factor alpha. Eur J Immunol (1995) 0.92
PI4P5-kinase Ialpha is required for efficient HIV-1 entry and infection of T cells. J Immunol (2008) 0.92
Induction of antibodies reactive to cardiac myosin and development of heart alterations in cruzipain-immunized mice and their offspring. Eur J Immunol (2000) 0.91
Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT. J Virol (1998) 0.91
Proteins synthesized by inducer T cells: evidence for a mitogenic peptide shared by inducer molecules that stimulate different cell types. Cell (1982) 0.91
Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile. J Control Release (2012) 0.90
Inhibitory effects of the Trypanosoma cruzi membrane glycoprotein AGC10 on the expression of IL-2 receptor chains and secretion of cytokines by subpopulations of activated human T lymphocytes. Eur J Immunol (1999) 0.90
IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta. J Immunol (1997) 0.89
Activation by synergism between endotoxin and lymphokines of the mouse macrophage cell line J774 against infection by Trypanosoma cruzi. Parasite Immunol (1987) 0.89
Replication of human immunodeficiency virus-1 in primary human T cells is dependent on the autocrine secretion of tumor necrosis factor through the control of nuclear factor-kappa B activation. J Allergy Clin Immunol (1997) 0.88
Phosphodiesterase 4 inhibitors prevent cytokine secretion by T lymphocytes by inhibiting nuclear factor-kappaB and nuclear factor of activated T cells activation. J Pharmacol Exp Ther (2001) 0.88
Physical association and functional relationship between protein kinase C zeta and the actin cytoskeleton. Eur J Immunol (1995) 0.88
A tubulin-related 55 kilodalton surface antigen recognized by different Trypanosoma cruzi stage-specific monoclonal antibodies from infected mice. Mol Biochem Parasitol (1988) 0.88
Viral phenotype affects the thymic production of new T cells in HIV-1-infected children. AIDS (2001) 0.88
Encephalitozoon microsporidia modulates p53-mediated apoptosis in infected cells. Int J Parasitol (2006) 0.88
Characterization of a glycosyl-phosphatidylinositol-anchored membrane protein from Trypanosoma cruzi. Infect Immun (1991) 0.88
Regulation of human immunodeficiency virus type 1 replication in human T lymphocytes by nitric oxide. J Virol (2001) 0.87
Specific patterns of CD4-associated immunosenescence in vertically HIV-infected subjects. Clin Microbiol Infect (2012) 0.87
Restriction of poliovirus RNA translation in a human monocytic cell line. Eur J Biochem (1989) 0.87
Expression of IkappaBalpha in the nucleus of human peripheral blood T lymphocytes. Oncogene (1999) 0.86
Allelic selection of human IL-2 gene. Eur J Immunol (2000) 0.86
Specific effect of anti-transferrin antibodies on natural killer cells directed against tumor cells. Evidence for the transferrin receptor being one of the target structures recognized by NK cells. J Immunol (1985) 0.86
Inhibitory effects of 'cap' analogues on globin mRNA and encephalomyocarditis RNA translation in a reticulocyte cell-free system. Eur J Biochem (1980) 0.85
Involvement of nitric oxide on the cytokine induced growth of glial cell. Biochem Biophys Res Commun (1993) 0.85
The efficacy of photochemical treatment with methylene blue and light for the reduction of Trypanosoma cruzi in infected plasma. Vox Sang (2006) 0.85
A colorimetric assay based on cell viability for the indirect detection of intracellular replication and killing of Trypanosoma cruzi. J Immunol Methods (1987) 0.85
Sino-nasal adenocarcinoma: epidemiological and clinico-pathological study of 34 cases. J Otolaryngol (1993) 0.84
Affinity-purified antigen-specific products produced by T cells share epitopes recognized by heterologous antisera raised against several different antigen-specific products from T cells. Cell Immunol (1983) 0.84
Female sex hormones regulate the Th17 immune response to sperm and Candida albicans. Hum Reprod (2013) 0.84
Serum levels of fibrosis biomarkers measured early after liver transplantation are associated with severe hepatitis C virus recurrence. Transpl Infect Dis (2009) 0.83
Bacteriocin 28b, a chromosomally encoded bacteriocin produced by most Serratia marcescens biotypes. Res Microbiol (1996) 0.83
Immunological properties of a DNA plasmid encoding a chimeric protein of herpes simplex virus type 2 glycoprotein B and glycoprotein D. Vaccine (2003) 0.83
Disruption in cytokine and chemokine production by T-cells in vertically HIV-1-infected children. Acta Paediatr (2001) 0.83
Alkylating nucleosides 1. Synthesis and cytostatic activity of N-glycosyl(halomethyl)-1,2,3-triazoles. A new type of alkylating agent. J Med Chem (1979) 0.83
Mapping of genetic deletions on the long arm of chromosome 22 in human pancreatic adenocarcinomas. Anticancer Res (2001) 0.83
Correlation of viral load and CD8 T-lymphocytes with development of neurological manifestations in vertically HIV-1-infected infants. A prospective longitudinal study. Neuropediatrics (1999) 0.83
Laminin receptor in lymph node negative breast carcinoma. Cancer (1999) 0.83
EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity. Oncogene (2011) 0.82
Antiparasitic effects of the intra-Golgi transport inhibitor megalomicin. Antimicrob Agents Chemother (1998) 0.82
Dexamethasone induces lipocalin-type prostaglandin D synthase gene expression in mouse neuronal cells. J Neurochem (2000) 0.82
Inhibition of interleukin 2-induced proliferation of cloned murine T cells by glucocorticoids. Possible involvement of an inhibitory protein. Eur J Immunol (1988) 0.82
Synergy of tumor necrosis factor with protein kinase C activators on T cell activation. Eur J Immunol (1990) 0.82
GP 50/55, a membrane antigen of Trypanosoma cruzi involved in autoimmunity and immunosuppression. Biol Res (1993) 0.81
Megalomicin disrupts lysosomal functions. J Cell Sci (1997) 0.81
Alzheimer's amyloid precursor protein is expressed on the surface of hematopoietic cells upon activation. Biochim Biophys Acta (1996) 0.81
Different functional sites on rIFN-alpha 2 and their relation to the cellular receptor binding site. J Immunol (1987) 0.81
Regulation of interleukin-2 responses by phosphatidic acid. Eur J Immunol (1992) 0.81