PubRank

J M McCune

Author PubWeight™ 111.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. N Engl J Med 2001 5.33
2 Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat Med 1999 4.74
3 Infection of the SCID-hu mouse by HIV-1. Science 1988 4.37
4 Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J Immunol Methods 2001 4.25
5 HIV induces thymus depletion in vivo. Nature 1993 3.73
6 Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med 2001 3.69
7 Long-term human hematopoiesis in the SCID-hu mouse. J Exp Med 1990 3.59
8 HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol 2008 3.36
9 Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse. J Exp Med 1993 2.81
10 HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes. Am J Transplant 2007 2.50
11 Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS 2001 2.47
12 Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA. Proc Natl Acad Sci U S A 2002 2.46
13 Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nat Med 1998 2.27
14 Impaired replication of protease inhibitor-resistant HIV-1 in human thymus. Nat Med 2001 2.13
15 HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo. Immunity 1995 2.07
16 Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse. J Virol 1994 1.87
17 Isolation and immunologic characterization of a human. B-lymphocyte-specific, cell surface antigen. J Exp Med 1976 1.74
18 CCR5- and CXCR4-utilizing strains of human immunodeficiency virus type 1 exhibit differential tropism and pathogenesis in vivo. J Virol 1998 1.72
19 Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication. Proc Natl Acad Sci U S A 1993 1.70
20 Direct evidence for thymic function in adult humans. J Exp Med 1999 1.70
21 Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent. J Immunol 1991 1.65
22 CXCR4 and CCR5 expression delineates targets for HIV-1 disruption of T cell differentiation. J Immunol 1998 1.64
23 Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis. J Virol 1996 1.61
24 Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice. J Exp Med 1999 1.61
25 Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds. Antimicrob Agents Chemother 1996 1.54
26 Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry. Antimicrob Agents Chemother 1996 1.51
27 Two types of Ia-positive T cells. Synthesis and exchange of Ia antigens. J Exp Med 1980 1.47
28 Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. J Infect Dis 2000 1.43
29 T cell turnover in HIV-1 disease. Immunity 1997 1.35
30 Loss of cytomegalovirus-specific CD4+ T cell responses in human immunodeficiency virus type 1-infected patients with high CD4+ T cell counts and recurrent retinitis. J Infect Dis 2001 1.32
31 Implantation and maintenance of functional human bone marrow in SCID-hu mice. Blood 1992 1.31
32 Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia. J Exp Med 1980 1.28
33 Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse. J Immunol 1991 1.26
34 Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects. Virology 2001 1.23
35 Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N-termini and different C-termini. J Exp Med 1980 1.21
36 Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouse. Proc Natl Acad Sci U S A 1991 1.21
37 Enhanced representation of HL-A antigens on human lymphocytes after mitogenesis induced by phytohemagglutinin or Epstein-Barr virus. Proc Natl Acad Sci U S A 1975 1.20
38 Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells. J Exp Med 1991 1.16
39 Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo. Blood 1998 1.14
40 Reversal of human immunodeficiency virus type 1-associated hematosuppression by effective antiretroviral therapy. Clin Infect Dis 2000 1.14
41 J chain biosynthesis in pre-B cells and other possible precursor B cells. J Exp Med 1981 1.10
42 Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner. J Infect Dis 1991 1.07
43 Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice. J Exp Med 1999 1.06
44 Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: evidence of indirect mechanisms. J Immunol 1999 1.03
45 Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice. Antimicrob Agents Chemother 2000 1.03
46 Development of a human thymic organ culture model for the study of HIV pathogenesis. AIDS Res Hum Retroviruses 1995 1.00
47 Causal relationships between HIV-1 coreceptor utilization, tropism, and pathogenesis in human thymus. AIDS Res Hum Retroviruses 2000 0.98
48 The immunoglobulin-like structure of human histocompatibility antigens. Fed Proc 1976 0.97
49 The scid-hu mouse: current status and potential applications. Curr Top Microbiol Immunol 1989 0.94
50 Human hematolymphoid cells in SCID mice. Curr Opin Immunol 1994 0.94
51 R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus. J Virol 1999 0.90
52 Cytomegalovirus (CMV)-specific CD4+ T lymphocyte immune function in long-term survivors of AIDS-related CMV end-organ disease who are receiving potent antiretroviral therapy. J Infect Dis 2001 0.89
53 Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro. Proc Natl Acad Sci U S A 1981 0.89
54 Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. J Exp Med 1987 0.88
55 Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans. Genes Immun 2011 0.86
56 Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320. Antimicrob Agents Chemother 1998 0.85
57 Ig biosynthesis in a human pre-B cell line. J Immunol 1981 0.85
58 Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1. J Virol 2000 0.85
59 Superantigen-mediated deletion of specific T cell receptor V beta subsets in the SCID-hu Thy/Liv mouse is induced by staphylococcal enterotoxin B, but not HIV-1. J Immunol 1997 0.84
60 A membrane-bound Fas decoy receptor expressed by human thymocytes. J Biol Chem 2000 0.82
61 Direct evaluation of radiation damage in human hematopoietic progenitor cells in vivo. Radiat Res 1994 0.81
62 Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains. J Exp Med 1981 0.81
63 Human neural xenografts: progress in developing an in-vivo model to study human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV) infection. Adv Neuroimmunol 1994 0.78
64 Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal. J Immunol 1999 0.77
65 UV irradiation of polystyrene pipets releases PCR inhibitors. Biotechniques 1998 0.76
66 Today's SCID-hu mouse. Nature 1990 0.76
67 Pseudotypes in HIV-infected mice. Science 1990 0.76
68 Epstein-Barr virus associated lymphoproliferative disease in mice and men. Lab Invest 1991 0.75
69 Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. Lymphat Res Biol 2006 0.75
70 Furry flasks? Nat Biotechnol 1998 0.75
71 The diversity of T cells. N Engl J Med 2001 0.75